1.Clinical Significance of DNA Ploidy in Epithelial Ovarian Malignancy.
Byung Young LEE ; Hyun Chan KIM
Korean Journal of Gynecologic Oncology and Colposcopy 1996;7(4):283-290
Prognosis and biologic behavior of malignant ovarian tumors have been assessed by clinical staging, morphological grading and many other variables. Recently DNA ploidy measured by flow cytometry has been suggested as an additional important indicator of the tumor behavior and prognosis. The author measured DNA ploidy, S-phase fraction and DNA Index in 36 patients of epithelial ovarian tumors(17 were malignant, and 19 were borderline) by flow cytometric analysis of paraffin embedded tumor blocks. Comparing with FIGO stage, tumor grade, histologic type and others, the author investigated the clinical significance of the results of flow cytometric analysis. The results obtained as follows : (continue)
DNA*
;
Flow Cytometry
;
Humans
;
Paraffin
;
Ploidies*
;
Prognosis
2.A study on fracture strength and color by the design of metal coping in ceramo metal crown.
Myung Ho LEE ; Young Chan JEON
The Journal of Korean Academy of Prosthodontics 1992;30(1):103-124
No abstract available.
Crowns*
3.Inflammatory Pseudotumor of the Liver: A case report.
Sang Chirl LEE ; Chang Su LEE ; Chan Young LEE
Korean Journal of Gastrointestinal Endoscopy 1987;7(1):87-89
The term "collagenous colitis" was coined by Lindstrom in 1976 to describe the patient with chronic watery diarrhea who had normal rectal mucosa by proctoscopy but who had a thick subepithelial collagenous deposit on biopsy, and now collagenous colitis is recognized as one of the more common causes of chronic diarrhea of obscure origin. But in this country only a few case has been reported. We have seen a 68-year-old man with chronic watery diarrhea with abdominal pain. Physical examination, laboratory and radiologic studies were no abnormal finding. Colonoscopy disclosed grossly normal mucosa through the entire colon but by histologic examination there are chronic inflammation in the lamina propria and thickened subepithelial collagen layer. Symptoms and pathologic findings of patient improved after treatment with sulfasalazine and prednisolone. (Korean J Castraintest Endosc 17: 79-84, 1997)
Abdominal Pain
;
Aged
;
Biopsy
;
Colitis, Collagenous
;
Collagen
;
Colon
;
Colonoscopy
;
Diarrhea
;
Granuloma, Plasma Cell*
;
Humans
;
Inflammation
;
Liver*
;
Mucous Membrane
;
Numismatics
;
Physical Examination
;
Prednisolone
;
Proctoscopy
;
Sulfasalazine
4.Syringocystadenoma Papilliferum Giganteum: Report of A Case.
Young Chan CHOI ; Young Keun KIM ; Sung Nack LEE
Korean Journal of Dermatology 1977;15(4):493-497
Syringocystadenoma papilliferum is s rare tumor of disputed origin that was first reorted by peterson in 1892. Theclinical features of syringocystadenoma papilliferum are not constant. It may be present at birth or develop later in life. Its appearance varies from an irregular, flat, grey or reddish area to a grey or dark brown. raised and cauliflower-like surface. Sometimes it is moist, flesh or pedunculated and occasionally a verrucous plaque, or cyst may be seen. The typical lesion occurs most frequently on the scalp, and is a hairless smooth plaque until puberty, when a nodular verrucous transformation occurs. A 39 years old male patient had egg sized (3*5cm) and yellowish red colored verrucous tumor mass on his epigastric area, which had grown up slowly for 7 years. The diagnosis of syringocysyadenoma papilliferum was confirmed by histological examination. We repoet a case of syringocystadenoma papilliferum in unusually large size on the epigastric area.
Adolescent
;
Adult
;
Diagnosis
;
Humans
;
Male
;
Ovum
;
Parturition
;
Puberty
;
Scalp
5.Assesment of tubal patency : Transvaginal sonosalpingography(TV-SSG) versus hysterosalpingography(HSG).
Jae Young LEE ; Byung Young LEE ; Eun Kwan LEE ; Byung Ik LEE ; Hyun Chan KIM
Korean Journal of Obstetrics and Gynecology 1993;36(7):1962-1966
No abstract available.
Equidae*
6.Chromomycosis: A case report.
So Young JIN ; Chan Il PARK ; Yoo Bock LEE
Korean Journal of Pathology 1985;19(3):365-367
Chromomycosis is a chronic localized infection of the cutaneous and subcutaneous tissues and characterized by verrucoid, ulcerated and crusted lesions with sclerotic margins. It histologically show confluent granulomatous nodules containing large giant cells of the foreign body type. The organisms are differ from other yeastform fungi by the characteristic chestnut-brown color and by the septate division. A case of 51 year old woman with chromomycosis at submental area is presented.
Female
;
Humans
7.Epidemiological conditions of Metagonimus yokogawai infection in Hadong Gun, Gyeongsang Nam Do.
Dong Chan KIM ; On Young LEE ; Eui Beom JEONG
The Korean Journal of Parasitology 1979;17(1):51-59
An epidemiological investigation was conducted on Metagonimus yokogawai infection in Hadong Gun (County), Gyeongsang Nam Do, Korea, and following findings were obtained. Overall prevalence rate of Metagonimus yokogawai infection was 29.1 percent from a total of 1,163 inhabitants examined. By area of river and stream, Seomjin-gang R.: 9.5 percent (out of 95 inhabitants examined) in Jeondo Ri in the lower river, 19.9 percent (156) at Dugog Ri near Hadong town, and 90.8 percent (65) in Tab Ri of Hwagae Myeon where Hwagae-cheon Stream joins; Hwagae-Cheon Stream: 42.2 percent (45) in Yonggang Ri of the middle stream and 27.5 percent (72) in Daeseong Ri of the upper stream; Hoengcheon-gang R.: 54.7 percent (161) in Gojeol Ri of the lower river, 40.6 percent (128) in Hoengcheon Ri of the middle stream, and 5.4 percent (93) in Jungi Ri of the upper stream, and 43.8 percent (89) in Uge Ri located along a tributary of the Hoengcheon-gang R. and 4.0 percent (101) in Jangam Ri which is located about 4 km away from the river; Deogcheon-gang R.: 18.5 percent (54) in Munam Ri; Gwangog-cheon Stream: 2.8 percent (107) in Gwangog Ri. The difference in prevalence rate of the infection by area was correlated with the opportunity and amount of raw eating of sweetfish by the inhabitants in the respective areas. By age and sex, the overall prevalence rate increased from young age group and reached a peak at 20-29 age group and then the rate decreased gradually. In high endemic areas, however, a peak level of the rate lasted up to 40-49 age group in male. On the other hand, in low endemic areas, the rate was significantly lower in female, though moderate level of the infection was seen in male. The overall prevalence rate was higher in male than in female and the difference was greater in middle age groups. The most significant mode of infection by the inhabitants was the raw eating of sweetfish which commonly harbour metacercariae of M. yokogawai during summer through autumn. Besides, it was noted that the infection can be acquired through contamination with the metacercariae on food of various side-dish and kitchen utensils as well as on hands of a cook when such fish are prepared or handled. The inhabitants usually begin to acquire infection from early June of a year when fishing of sweetfish opens and acquire infection more frequently in July and August when fish are caught more productively and favored for raw consumption by inhabitants. From September, sweetfish are no more favored for raw consumption and accordingly are dried and cooked in this season. The infection in the sweetfish Plecoglossus altivelis as the second intermediate host was first observed from May with low level of infection and the intensity of infection in a fish rapidly increased until reaching a peak in October when sweetfish season normally ends. The first intermediate host snail of M. yokogawai in this area was Semisulcospira coreana (Martens) which is widely distributed in the streams and rivers in this locality.
parasitology-helminth-trematoda
;
Metagonimus yokogawai
;
metacercaria
;
Plecoglossus altivelis
;
epidemiology
8.Analysis of Mitochondrial DNA in Patients with Essential Tremor.
Uhn LEE ; Young Mi YOO ; Chan Jong YOO
Journal of Korean Neurosurgical Society 2000;29(2):188-195
No abstract available.
DNA, Mitochondrial*
;
Essential Tremor*
;
Humans
9.Scleroderma Treated with Penicillamine-D.
Young Chan CHOI ; Yoon Kee PARK ; Sung Nack LEE
Korean Journal of Dermatology 1977;15(4):483-492
Scleroderma is an incidious and chronic disease of unknown cause. The clinical picute of scleroderma is characterized by the apperance of circumscribed of diffuse, hard, smooth, ivory colored areas that are immobile upon upon the underlying tissues. It may be classified to as a localized form (morphea) and a systemic scleroderma or progressive systemic sclerosis (PSS) which is characterized by diffuse involvment of the connective tissue of the skin and certain intemal organs. The authors observed 3 cases of PSS and 6 cases of morphea. They have complained of marked sclerosis or thickening of skin or slowly developing dyspneadue to interstitial pulmonary fibrosis which were confirmed by chest X-ray. Recently, penicillamine-D has been advocated as a beneficial agent in scleroderma by Asboe-Hansen. therefore, penicillamine-D was administered to the above patients. Two of PSS were markedly improved with normal skin softness. Two of morphea were also moderately improved. Other patients remained stationary or no effect.
Chronic Disease
;
Connective Tissue
;
Humans
;
Pulmonary Fibrosis
;
Scleroderma, Diffuse
;
Scleroderma, Localized
;
Scleroderma, Systemic
;
Sclerosis
;
Skin
;
Thorax
10.Expression of bcl-2 and c-myc Proteins in Epidermal and Melanocytic Tumors.
Young Ha OH ; Chan Kum PARK ; Jung Dal LEE
Korean Journal of Pathology 1996;30(9):810-818
bcl-2 and c-myc protein expression were studied in 44 epidermal (8 seborrheic keratoses, 21 squamous cell carcinomas, and 15 basal cell carcinomas), and 26 melanocytic tumors(8 nevi, and malignant melanomas) by immunohistochemistry using the specific anti-bcl-2 and anti-c-myc monoclonal antibodies. 14 out of 15 basal cell carcinomas(BCC) (93.3%) showed expression of bcl-2 protein, 12 of which (85.7%) showed coexpression of c-myc protein. In the melanocytic tumors, 7 out of 8 nevi showed bcl-2 expression (87.5%). Five of these 7 cases (62.5%) also showed c-myc protein expression. Eight of 18 malignant melanomas(MM) (44.4%) showed expression of bcl-2 protein and 7 of these 8 cases (38.9%) also showed c-myc protein expression. All seborrheic keratoses and squamous cell carcinoma(SCC) were negative for bcl-2 proteins. 12 of 15 SCCs(80%) were positive for c-myc protein. In conclusion, bcl-2 and c-myc proteins were coexpressed in BCCs, nevi, and MMs. Coexpression of bcl-2 and c-myc proteins in these tumors was statistically significant(p<0.01), while no considerable differences of bcl-2 and c-myc expression were found between nevi and MMs. These results suggests that bcl-2 may cooperate with c-myc to promote tumorigenesis of BCCs, nevi, and MMs(p<0.01).
Cell Transformation, Neoplastic