No abstract available.
Atrophy ; Pityriasis* ; Tinea Versicolor*

Circumscribed palmar or plantar hypokeratosis is a rare dermatosis, and it consists of asymptomatic erythematous, well-circumscribed and depressed patch with scaly borders on the palm or sole. It usually affects middle-aged or elderly women. Histopathologically, it has a sharp stair between the normal and involved skin, and a demarcated area with an abrupt decrease in the horny layer thickness. We report herein a case of circumscribed palmar hypokeratosis that was successfully treated with cryotherapy.
Aged ; Cryotherapy ; Female ; Humans ; Skin ; Skin Diseases

Circumscribed palmar or plantar hypokeratosis is a rare dermatosis, and it consists of asymptomatic erythematous, well-circumscribed and depressed patch with scaly borders on the palm or sole. It usually affects middle-aged or elderly women. Histopathologically, it has a sharp stair between the normal and involved skin, and a demarcated area with an abrupt decrease in the horny layer thickness. We report herein a case of circumscribed palmar hypokeratosis that was successfully treated with cryotherapy.
Aged ; Cryotherapy ; Female ; Humans ; Skin ; Skin Diseases

BACKGROUND: Female pattern hair loss (FPHL) is the most common type of pattern hair loss in women. It has been suggested that FPHL is associated with several serological abnormalities. OBJECTIVE: The aim of this study is to investigate the clinical characteristics and serological abnormalities of the Korean FPHL patients and to compare them with the data from the Korea National Health and Nutrition Examination Survey V and other relative reports. METHODS: We retrospectively evaluated the age, duration and comorbidities in 264 Korean patients who have been diagnosed with FPHL. Serum levels of serum iron, total iron binding capacity, ferritin, hemoglobin, free thyroxine (T4), thyroid stimulating hormone, testosterone and 25-(OH) vitamin D were being investigated. RESULTS: FPHL was most commonly found in patients aged from 20 to 29 years old and 55% of the patients visited the hospital one year after the onset of FPHL. In FPHL patients, the levels of testosterone, hemoglobin, serum ferritin, 25-(OH) vitamin D, thyroid stimulating hormone were all significantly higher than the average Korean adult women. And, the free thyroxine level was significantly lower than the average Korean adult women. When analyzed according to the menopausal status, premenopausal FPHL patients showed significantly higher serum levels of hemoglobin, ferritin, and 25-(OH) vitamin D than those of the Korean adult women. But, the postmenopausal FPHL patients showed significantly higher serum levels of 25-(OH) vitamin D than those of Korean adult women. CONCLUSION: The levels of ferritin, testosterone and vitamin D of FPHL patients were elevated higher than those of the Korean adult women. To confirm these results in the future, further large scaled evaluation is suggested.
Adult ; Comorbidity ; Female* ; Ferritins ; Hair* ; Humans ; Iron ; Korea ; Nutrition Surveys ; Retrospective Studies ; Testosterone ; Thyrotropin ; Thyroxine ; Vitamin D

No abstract available.
Female ; Humans

No abstract available.
Alopecia ; Minoxidil

Disseminated superficial porokeratosis is a keratinization disorder characterized by multiple brown, atrophic patches with sharply demarcated and hypertrophic ridges. Atypical cases of disseminated superficial porokeratosis with acute exacerbation accompanied by severe pruritus have been reported as "eruptive pruritic papular porokeratosis" or "inflammatory disseminated superficial porokeratosis." We report a case of inflammatory disseminated superficial porokeratosis in a 53-year-old man who was successfully treated with oral isotretinoin.
Humans ; Isotretinoin ; Keratins ; Middle Aged ; Porokeratosis ; Pruritus

Erlotinib is a small-molecule tyrosine kinase inhibitor (TKI) of the epidermal growth factor receptor (EGFR). Erlotinib has been used primarily to treat non-small cell lung cancer. In addition to its role in tumor cells, EGFR is also an important regulator of growth and differentiation in the skin and hair. Therefore, EGFR-TKIs have been associated with a number of cutaneous side effects including follicular acneiform eruptions, cutaneous xerosis, chronic paronychia, desquamation, seborrheic dermatitis, and hair texture changes. Herein, we report a rare case of a 61-year-old woman who was treated with erlotinib and experienced cicatricial alopecia.
Acneiform Eruptions ; Alopecia ; Carcinoma, Non-Small-Cell Lung ; Dermatitis, Seborrheic ; Female ; Hair ; Humans ; Middle Aged ; Paronychia ; Protein-Tyrosine Kinases ; Quinazolines ; Receptor, Epidermal Growth Factor ; Skin ; Erlotinib Hydrochloride

Follicular mycosis fungoides is a distinct variant of mycosis fungoides. Clinically, it occurs mostly in adults, affecting more males than females. It is manifested as pruritic follicular papules, acneiform lesions, or indurated plaques, typically in the head and neck. Histopathologically, it is characterized by infiltration of atypical T lymphocytes with cerebriform nuclei in the follicular epithelium (folliculotropism). We report a case of follicular mycosis fungoides manifested as a milia-like lesion combined with the patch stage of mycosis fungoides, which was treated with radiotherapy.
Adult ; Epithelium ; Female ; Head ; Humans ; Male ; Mycosis Fungoides* ; Neck ; Radiotherapy ; T-Lymphocytes

Lichen Planus Pigmentosus (LPP), an uncommon variant of lichen planus, is clinically characterized by insidious onset of diffuse or reticulated hyperpigmented patches on the sun-exposed areas and flexural folds. Histopathologic findings of LPP show atrophic epidermis with vacuolar degeneration of the basal cell layer and sparse lichenoid lymphohistiocytic infiltration with melanophages in the dermis. Although there have been few reports of LPP, clinical and histological pathogenesis and prognosis are not well known. Herein, we describe a case of linear LPP along the Blaschko's lines in 34-year old Korean man who presented with linear hyperpigmented, dark brown patches on his left thigh, repeatedly developing new lesions of erythematous reticular patches since puberty. This report shows the early events of LPP and the protracted course.
Dermis ; Epidermis ; Lichen Planus ; Lichens ; Prognosis ; Puberty ; Thigh