1.A Case of Forehead Plaque as an Initial Sign of Tuberous Sclerosis.
You Chan KIM ; Jeong Hwa LEE ; Yong Woo CINN
Korean Journal of Dermatology 1995;33(1):201-205
Tuberous sclerosis is a systemic disorder of hamartoma format on includes facial angiofibromas, subungal fibromas, hypomelanic maciles Shagreens patches. The earliest skin manifestation of tuberous sileiule, but it may appear later. We present a case of fibrous plaqu a recognized skin signs. Forehead plaque can be the earliest skin near in many organs. Skin involvement less forehead fibrous plaques, and vsis is usually hypornelanotic inacipearing before any of these more festation of tuberous sclerosis. Its presence may lead to early diagnosis and appropriate genetic couise hng hut may be a poor prognostic sign.
Angiofibroma
;
Early Diagnosis
;
Fibroma
;
Forehead*
;
Hamartoma
;
Skin
;
Skin Manifestations
;
Tuberous Sclerosis*
2.A Case of Eyelid oil Granuloma Caused by High Pressure Injury.
You Chan KIM ; Yong Woo CINN ; Jeong Hwa LEE
Korean Journal of Dermatology 1995;33(1):197-200
Oil granuloma is a foreignbody reaction which occurs after injection of lipid usually for cosmetic or therapeutic reasons. I present a case of eyelid oil granuloma caused by accidental high pressure injury in a 39-year-old man. The patient had a 2 x 0.5cm sized, firm, normardear subcutaneous nodule on the Rt. upper eyelid. Histopathologic examination showed a characteris swiss-cheese appearance. Eyelid oil granuloma caused by high pressure injury is very rare and my case is the first described in Korean medical literatures.
Adult
;
Eyelids*
;
Granuloma*
;
Humans
3.The Significance of Nesidiodysplasia of the Pancreas.
Soo Im CHOI ; Woo Hee JEONG ; Chan Il PARK
Korean Journal of Pathology 1990;24(1):10-15
To elucidate the significance of the nesidiodysplasia of pancreas, histological re-evaluation and immunohistochemical studies for insulin, glucagon and somatostatin were done on 16 consecutive cases (5 premature babies, 2 stillborns, 5 infants and 3 adults) in which paraffin blocks of the pancreas were available. Only one infant was hypoglycemic. All 16 pancreases showed changes of nesidiodysplasia which appeared immunohistochemically to have isulin, glucagon and /or somatostatin. The histologic patterns of nesidiodysplasia included ductoendocrine proliferation, endocrine cell dysplasia, adenomatosis, septal islet, islket cell hypertrophy and islet hypertrophy. All the patterns of nesidiodysplasia except for the adenomatosis were seen in premature babies, infants, stillborns and adults with or without hypoglycemia. The adenomatosis was found only in the hypoglycemic infant. The result suggests that all patterns of nesidiodysplasia of other than the adenomatosis does not imply the pathologic basis of hypoglycemia.
Infant
;
Adult
;
Male
;
Female
;
Humans
4.A Case of 13 Ring Chromosome Syndrome.
Chan Jeong PARK ; Byeong Il LIM ; Hyeon Jeong CHO ; Kih Yeon SONG ; Kwang Woo KIM
Journal of the Korean Child Neurology Society 1998;5(2):383-387
We have experienced a case of 13 ring chromosome in a 40-month-old girl who demonstrated psychomotor retardation with delayed speech, growth retardation, hearing loss(left), microcephaly, trigonocephaly with flat occiput, hypertelorism, epicanthal folds, microophthalmia, broad prominamt nasal bridge, high arched palate, micrognathia, large auricles and other anomalies. Cytogenetic studies of peripheral blood lymphocytes with differential staining of chromosomes revealed 46, XX, r13. Her parents' karyotypes were normal. We reported the case with the review of the associated literatures.
Child, Preschool
;
Craniosynostoses
;
Cytogenetics
;
Female
;
Hearing
;
Humans
;
Hypertelorism
;
Karyotype
;
Lymphocytes
;
Microcephaly
;
Palate
;
Ring Chromosomes*
5.Ultrastructural Study of Vitiligo.
Chan Woo JEONG ; Il Yeong SON ; Un Cheol YEO ; Joungho HAN ; Eil Soo LEE
Annals of Dermatology 2001;13(3):158-162
BACKGROUND: There is a long-standing controversy whether melanocytes in vitiligo of more than 1 year duration are actually lost or still present. Resolving this matter is essential in understanding the underlying pathology and for the development of the treatment. On previous immunohistochemical and ultrastructural studies of vitiligo lesions, damage of melanocyte and keratinocyte in early lesions were reported and complete absence of melanocyte in long standing lesions were known. OBJECTIVE: This study aimed to determine the existence of the differences in pathologic changes in melanocytes according to the duration of the lesion. METHODS: We investigated the vitiliginous skin samples from 31 patients with early(less than 1 year duration) vitiligo and 30 patients with long standing(l to 5 years duration) vitiligo under the electron microscopy. RESULTS: Multiple degenerative changes in melanocytes were observed in the early and long standing lesions. In long standing lesions, degeneration of melanocytes including pyknotic, in-dented nuclei, vacuolated cytoplasms and blunted dendrites were more pronounced than early lesions. Even in long standing lesions, definite or presumptive melanocytes were observed in 16(53.3%) of 30 cases. CONCLUSION: Our results suggest that the melanocytes of vitiligo lesions were damaged and that the percentage of degenerative changes increase in accordance with the duration of the lesion. However, in long standing lesions as well as in early lesions, some residual melanocytes can be observed ultrastructurally.
Cytoplasm
;
Dendrites
;
Humans
;
Keratinocytes
;
Melanocytes
;
Microscopy, Electron
;
Pathology
;
Skin
;
Vitiligo*
6.A Clinical Study of Recurrent Intussusception.
Hae Ok KIM ; Jae Oh KIM ; Jeong Woo SUK ; Keun Chan SOHN
Journal of the Korean Pediatric Society 1981;24(12):1173-1184
No abstract available.
Intussusception*
7.Post-zoster Granuloma.
Hyang Joon PARK ; Jeong Heon LEE ; You Chan KIM ; Yong Woo CINN
Annals of Dermatology 1998;10(1):64-66
We present a patient who developed granuloma in a previous herpes zoster scar (post-zoster granuloma). The development of granuloma in healed herpes zoster lesions may represent an atypical delayed hypersensitivity reaction to viral antigens or tissue antigens altered by the virus. To our knowledge, this is the first case reported in Korean literature.
Antigens, Viral
;
Cicatrix
;
Granuloma*
;
Herpes Zoster
;
Humans
;
Hypersensitivity, Delayed
8.A Case of Giant Basal Cell Carcinoma.
Jeong Heon LEE ; Hyang Joon PARK ; You Chan KIM ; Yong Woo CINN
Annals of Dermatology 1997;9(3):236-238
Giant basal cell carcinoma(BCC) is a clinical expression of a large-sized BCC, which can cause extensive local invasion and disfigurement and have a particular capacity for metastasis. In the development of this large tumor, several risk factors including patient neglect, aggressive histological features and long duration, are identified. We have observed a very large BCC on the forehead of anlderly man for more than 4 years. He had been suffering from psychiatric disease for a long time, and patient neglect due to this problem played a crucial role in the development of this giant BCC.
Carcinoma, Basal Cell*
;
Forehead
;
Humans
;
Neoplasm Metastasis
;
Risk Factors
9.Two Cases of Neurofibrosarcoma Arising from Cutaneous Neurofibroma in Patients with Neurofibromatosis.
Jeong Heon LEE ; You Chan KIM ; Hyang Joon PARK ; Yong Woo CINN
Korean Journal of Dermatology 1998;36(5):924-927
Neurofibrosarcoma is the most common malignant change in patients with neurofibromatosis. But the incidence of neurofibrosarcoma arising from cutaneous neurofibroma is very low. We report two cases of neurofibrosarcoma arising from cutaneous neurofibroma in patients with neurofibromatosis showing typical clinical manifestations.
Humans
;
Incidence
;
Neurofibroma*
;
Neurofibromatoses*
;
Neurofibrosarcoma*
10.A Survey on the Mode of Working of Estheticians in OECD Member Nations andSome Asian Countries in Relation to Medical Service.
Chan Woo JEONG ; Seung Kyung HANN ; Chang Hun HUH ; Hae Jun SONG
Korean Journal of Dermatology 2008;46(9):1149-1154
In 2008, Korea has enacted new ordinances about the role of estheticians, but this law can be interpreted ambiguously, restricting hiring of estheticians in medical clinics. The purpose of the study is to obtain information about medical-esthetic systems in other countries. We have taken a survey of this object from 30 OECD & Asian countries, and the questionnaires returned from a total of 22 countries (Australia, Austria, Canada, Denmark, Finland, France, Germany, Hungary, Japan, Netherlands, New Zealand, Norway, Portugal, Slovak Republic, Spain, Switzerland, Turkey, United Kingdom, United States, Singapore, Israel, and Thailand), were used for the final analysis. The results are summarized as follows. In most countries, estheticians working independently deal with only healthy, normal skin. In most countries, estheticians working independently have no right to operate any medical instruments. In all 17 countries that returned the questionnaires medical clinics can employ estheticians, and only theses estheticians who belong to the medical clinics can handle the non-invasive medical instruments under the supervision of doctors. In 17 countries that have related legal regulations, nurses, under the control of doctors, can perform wider range of duties in various settings than estheticians. The survey concludes that the duties of estheticians are closely related with medical skin care services and estheticians can perform various non-invasive medical procedures only under the control of doctors. From consulting a variety of medical-esthetic systems in other countries, we propose that the estheticians be allowed to work in medical clinics to provide better medical services for the patients and to make more chances of employment for themselves.
Asian Continental Ancestry Group
;
Austria
;
Canada
;
Denmark
;
Employment
;
Finland
;
France
;
Germany
;
Great Britain
;
Humans
;
Hungary
;
Israel
;
Japan
;
Jurisprudence
;
Korea
;
Netherlands
;
New Zealand
;
Norway
;
Organization and Administration
;
Portugal
;
Questionnaires
;
Singapore
;
Skin
;
Skin Care
;
Slovakia
;
Social Control, Formal
;
Spain
;
Switzerland
;
Turkey
;
United States