2.Renin Assay: Part 1. Study on Plasma Renin Activity in Various Diseases.
Korean Circulation Journal 1973;3(1):19-31
1. Present study was made to observe the plasma renin activity in the patients of benign essential hypertension, malignant hypertension, acute or chronic glomerulonephritis, liver cirrhosis with or without ascites, congestive heart failure, and massive bleeding due to various causes. 2. It was found that the substance with constrictive action on the rat colon had the hypertensive action. 3. The normotensive group showed the renin activity of 1.81+/-1.18ng/ml. 4. Benign hypertension group showed the level of 3.14+/-3.27 ng/ml which was the significantly elevated level compared to the normal group. 5. Malignant hypertensive group showed 8.47+/-9.48 ng/ml, which was not only the apparently elevated value than that of normal group, but also showed significant difference from that of benign essential hypertension. 6. The levels of 5.6+/-2.88 ng/ml and 27.5+/-12.36 ng/ml in chronic and acute glomerulonephritis respectively showed the significantly elevated level than the normal group, and the difference between the acute and chronic glomerulonephritis was also found to be significant. 7. The hepatic cirrhosis with or without ascites showed the level of 3.77+/-2.83 ng/ml and 0.80+/-0. ng/ml respectively. The value of the former was the significantly elevated compared with the normal group, and the later was lowered. 8. The level of 11.11+/-4.12 ng/ml was significantly elevated compared to that of normal group in congestive heart failure. 9. It is suggested that the renin activity assumes to be changed to the kind and the phase of the diseases and according to present data of elevated renin activity in essential hypertension, renin may play a secondary role in essential hypertension rather than to be a primary.
Animals
;
Ascites
;
Colon
;
Glomerulonephritis
;
Heart Failure
;
Hemorrhage
;
Humans
;
Hypertension
;
Hypertension, Malignant
;
Liver Cirrhosis
;
Plasma*
;
Rats
;
Renin*
3.A Clinical and Histopathologic Study of Epidermal Cysts.
Annals of Dermatology 1994;6(2):157-161
BACKGROUND: Epidermal cysts are the most common of all cysts. OBJECTIVE: The purpose of this paper is to report the clinical and histopathologic features of epidermal cysts. METHODS: We reviewed the clinical and histopathologic features of 205 cases that were diagnosed with epidermal cysts at the department of dermatology in Anam Hospital of Korea University for 11 years, from January 1983 to December 1993. RESULTS: 1. Of the 3,400 cases of skin biopsy specimens, 205 cases were epidermal cysts(6%). There were 141 male cases (68.8%) and 64 female cases (32.2%). The ratio of male to female was 1:0.45. 2. Most patients with epidermal cysts belonged to age ranging from 20 to 59 with the highest incidence in the 3rd decade. 3. The site of predilection of the epidermal cysts were face 94(45.9%), trunk 37(18.0%), neck 23(11.2%), leg 21(10.2%), arm 19(9.3%),scalp 7(3.4%), scrotum 2(1.0%), and vagina 2(1.0%). 4. Histopathologically, 61 cases (29.3%) were ruptured. The most common cystic wall change was acanthosis followed by atrophy, hyperplasia, hypergranulosis, parakeratotis, basalioma-like change, squamous eddies, dyskeratosis. The most common cystic content was keratinous material followed by parakeratotic cells, pigment, bacterial colony, RBC, inflammatory cells, hair shaft, calcification, trichilemmal keratinization, pilomatricoma-like change. The most common stromal change was giant cells followed by fibrosis, granulation tissue formation,vessel proliferation, pigment. CONCLUSION: According to our results, which agree with those of Chung, the epidermal cysts occur as a disease particular to young men, especially on the face. Histopathologically, when an epidermal cyst ruptures and the contents of the cyst are released into the dermis, a considerable foreign body reaction with numerous multinucleated giant cells results.
Arm
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Atrophy
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Biopsy
;
Dermatology
;
Dermis
;
Epidermal Cyst*
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Female
;
Fibrosis
;
Foreign-Body Reaction
;
Giant Cells
;
Granulation Tissue
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Hair
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Humans
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Hyperplasia
;
Incidence
;
Korea
;
Leg
;
Male
;
Neck
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Rupture
;
Scrotum
;
Skin
;
Vagina
4.A clinical study of bloody nipple discharge.
Journal of the Korean Surgical Society 1993;44(6):809-813
No abstract available.
Nipples*
5.A Randomized Double - Blind Clinical Trial of 2,000cc vs. 4,000cc Preparation with Balanced Lavage Solution (Golytely) for Colonoscopy.
Chan Wook PARK ; Moon Sung LEE ; Jin Hong KIM ; Sung Won CHO ; Chan Sup SHIM
Korean Journal of Gastrointestinal Endoscopy 1991;11(2):369-378
To determine the most effective and tolerable method of preparation with Golytely for colonoscopy, 141 consecutive cases were randomly allocated to drink either 2,000cc(74 cases, Group I) or 4,000cc(67 cases, Group 2), with infusion rate of 1,000cc/h. The reaults were as follows. 1) The rates of effective colonic clearance in group 1 and group 2 was 94.6% and 94.0%, respectively. There is no significance difference between two groups. 2) There was no significant difference in the ingested volume until the first bowel movement and the time required for rectal efflunt to be clear between two groups. 3) Patient acceptance was higher in group 1 than in group 2. 4) Side effects were less noticed in group 1 than group 2, and incraased in body weight (average 0.8 kg) after ingestion of Golytely was observed only in group 2.
Body Weight
;
Colon
;
Colonoscopy*
;
Eating
;
Humans
;
Therapeutic Irrigation*
6.Endoscopic Prosthesis in Malignant Stricture.
Moon Sung LEE ; Chan Wook PARK ; Jin Hong KIM ; Sung Won CHO ; Chan Sup SHIM
Korean Journal of Gastrointestinal Endoscopy 1991;11(2):363-367
Non-operative palliative treatment for malignant colonic obstruction can sometimes be accomplished by the insertion of anorectal tube, endoscopic balloon dilation or endoscopic laser therapy. But these methods have some disadvantages, such as limitaation of activity, need of repetitive treatment and high-risk of perforation. Endoscopic prosthesis is generally accepted as a safe, effective palliative treatment for malignant esophageal stricture, because this method has no above disadvantages. Neverthless, there is only a few experence with endoecopic prosthesis in malignant colorectal stricture over the world. We report two cases which were safely, effectively performed endoscopic prosthesis in palliative treatment for their malignant rectal strictures.
Colon
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Constriction, Pathologic*
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Esophageal Stenosis
;
Laser Therapy
;
Palliative Care
;
Prostheses and Implants*
7.Endoscopic Enucleation of a Gastric Lipoma by Strip Biopsy.
Moon Sung LEE ; Chan Wook PARK ; Jin Hong KIM ; Sung Won CHO ; Chan Sup SHIM
Korean Journal of Gastrointestinal Endoscopy 1991;11(2):273-277
Gastric lipomas are rare benign submucosal tumors which can present the diagnostic and therapeutic problems. The preferred treattment is observation or local excision. Since preoperative diagnosis and differentation from malignant tumors can be difficult by use of the conventional diagnostic modalities such as X-ray or endoscopic examination, patients are sometimes subjected to more extensive surgical procedures than warranted. As to the diagnosis of submucosal tumors of the upper digestive tract, a newly developed diagnostic modality of endoscopic ultrasonography(EUS) allows us to visuialize the structures underlying the gastrointestinal wall in a noninvasive maneuver, and can contribute to make differential diagnosis and decision of management. Strip biopsy is an endascopic tissue resection technique which permits resection of both mucosal and submucosal tissue regardless of the morphological type of the lesion, because the submucosal saline injections during the procedures make the flat or depressed lesions to be elevated. Now, we report a 56-yr-old female which had a Yamada type I polypoid gastric submucosal lipoma in the antrum, which could be performed the different diagnosis and successful endoscopic removal by endoscopic ultrasonography and strip biopsy.
Biopsy*
;
Diagnosis
;
Diagnosis, Differential
;
Endosonography
;
Female
;
Gastrointestinal Tract
;
Humans
;
Lipoma*
8.Estimation of the Depth of Invasion in Depressed Type of Early Gastric Cancer by Endoscopic Ultrasonography.
Jin Hong KIM ; Chan Wook PARK ; Moon Sung LEE ; Sung Won CHO ; Chan Sup SHIM
Korean Journal of Gastrointestinal Endoscopy 1991;11(2):261-271
A new method for combining ultrasonography snd endoscopy, endoscopic ultrasonography (EUS), was developed to improve the diagnostic accuracy of ultrasound by direct image of the target lesion via the gastrointestinal lumen. EUS has the unique ability to provide clear sonographic images of the wall structure of the stomach. This capability can be ultilized in assessing the depth of cancer invasion of the stomach by identifying which layer the ultrasonographic change extends to. However, the depressed types of early gastric cancer(EGC) are often accompanied by ulcerative change in the tumor foci. And the ultrasonographic picture is also influenced by the ulcerative change. (continue...)
Endoscopy
;
Endosonography*
;
Stomach
;
Stomach Neoplasms*
;
Ulcer
;
Ultrasonography
9.The clinical evaluation for children with orthostatic proteinuria.
Chan Sung LEE ; Chong Guk LEE ; Sang Woo KIM
Journal of the Korean Pediatric Society 1989;32(11):1520-1525
No abstract available.
Child*
;
Humans
;
Proteinuria*
10.Syringocystadenoma Papilliferum Giganteum: Report of A Case.
Young Chan CHOI ; Young Keun KIM ; Sung Nack LEE
Korean Journal of Dermatology 1977;15(4):493-497
Syringocystadenoma papilliferum is s rare tumor of disputed origin that was first reorted by peterson in 1892. Theclinical features of syringocystadenoma papilliferum are not constant. It may be present at birth or develop later in life. Its appearance varies from an irregular, flat, grey or reddish area to a grey or dark brown. raised and cauliflower-like surface. Sometimes it is moist, flesh or pedunculated and occasionally a verrucous plaque, or cyst may be seen. The typical lesion occurs most frequently on the scalp, and is a hairless smooth plaque until puberty, when a nodular verrucous transformation occurs. A 39 years old male patient had egg sized (3*5cm) and yellowish red colored verrucous tumor mass on his epigastric area, which had grown up slowly for 7 years. The diagnosis of syringocysyadenoma papilliferum was confirmed by histological examination. We repoet a case of syringocystadenoma papilliferum in unusually large size on the epigastric area.
Adolescent
;
Adult
;
Diagnosis
;
Humans
;
Male
;
Ovum
;
Parturition
;
Puberty
;
Scalp