3.Primitive Neuroectodermal Tumor of the Ovary: A case report .
Chan Kwon JUNG ; Eun Sun JUNG ; Youn Soo LEE ; Byung Kee KIM ; Sun Moo KIM
Korean Journal of Pathology 1999;33(8):631-635
Primitive neuroectodermal tumors (PNET) of the ovary are rare tumors with an exclusive or almost exclusive malignant neuroectodermal composition, and are generally regarded as a monodermal expression of an ovarian teratoma. The tumors are basically identical with the lesions of the same name occuring typically in the central nervous system of children. These tumors consist chiefly of undifferentiated small cells resembling neuroblasts. There are also mature, well- differentiated neuroectodermal cells, such as astrocytes and ependymal cells. We report a case of ovarian PNET with glial and neuroblastic differentiation and focal teratomatous foci of non-neural tissue in a 17-year-old female.
Adolescent
;
Astrocytes
;
Central Nervous System
;
Child
;
Female
;
Humans
;
Neural Plate
;
Neuroectodermal Tumors, Primitive*
;
Ovary*
;
Teratoma
4.Effect of Interleukin-10 on Development of Murine Collagen-induced Arthritis.
Bin YOO ; Chan KIM ; Seung Won CHOI ; Mi Jung KIM ; Sun Whan OH ; Hee Bom MOON
The Journal of the Korean Rheumatism Association 1997;4(2):111-120
OBJECTIVE: To evaluate the effect of IL-10 on development of collagen-induced arthritis, on humoral and cellular immunity and on the endogenous production of IL-10 in DBA/1J mice. METHODS: DBA/1J mice were immunized with chicken type II collagen in Freund s complete adjuvant. Murine recombinant IL-10 was given intraperitoneally twice a week from the day of second immunization (week 3) in doses of 0.002ug, 0. 02ug and 0. 2ug for 3 different groups, respectively. Dexamethasone was injected in one group to suppress the arthritis development and this group was used as negative control group. Levels of anti-collagen antibodies, serum IL-10 and stimulation indices of splenic monocytes to collagen were measured at the end of study. RESULTS: The 0. 02ug IL-10 and 0. 2ug IL-10 treated groups developed earlier and more severe arthritis (week 6 and 8) compared to that of the control group while the 0. 002ug IL-10 group has shown similar course to the control group in terms of incidence and severity of arthritis, At week 10, all groups with or without IL-10 injections developed arthritis with similar degree of severity while dexamethasone group showed far less incidence and severity of arthritis. The serum levels of anti-collagen antibody, IL-10 and spleen monocyte stimulation indices to collagen antigen showed no difference among control group, IL-10 injected groups and dexamethasone injected group. CONCLUSION: This study shows IL-10 could worsen the arthritis in CIA with the dosage used in this study without significant influence on the level of anti-collagen antibodies or stimulation indices of spenic monocyte to collagen.
Animals
;
Antibodies
;
Arthritis
;
Arthritis, Experimental*
;
Chickens
;
Collagen
;
Collagen Type II
;
Dexamethasone
;
Immunity, Cellular
;
Immunization
;
Incidence
;
Interleukin-10*
;
Mice
;
Monocytes
;
Spleen
5.Clinical study of hysterosalpingography in infertile women.
Jung Ok REW ; Byung Sun KIM ; Dong Keun KIM ; Hye Ryun OH ; Chan Moo PARK
Korean Journal of Obstetrics and Gynecology 1992;35(11):1621-1629
No abstract available.
Female
;
Humans
;
Hysterosalpingography*
6.Systolic pressure amplification of the aortic pressure in children with congenital heart disease.
Chan Uhng JOO ; Byoung Geun LEE ; Sun Jun KIM ; Jung Soo KIM
Journal of the Korean Pediatric Society 1993;36(2):232-238
Direct intraarterial measurement of blood pressure is an important diagnostic procedure in critical patients and premature baby care. Direct measurement was more accepted and confident method in physician than the indirect methods. But the presence of a significant amplification of systolic pressure in peripheral artery may lead to important error. So we have investigated the degree of the systolic pressure amplification from the ascending aorta to the femoral artery in children. Pressure waves recorded in the ascending aorta, aortic arch, diaphragmatic level of the descending aorta, common iliac artery, and femoral artery in 37 patients with congenital heart disease, aged 9 months to 21 years old (mean 7.16 yrs old) during diagnostic cardiac catheterization. The results were as follows 1) Amplification of the systolic pressure increased progressively from the ascending aorta to the femoral artery (16.7%) 2) Diastolic pressure decreased progressively from the ascending aorta to the femoral artery (6.5%) 3) Mean pressure decreased progressively from the ascending aorta to the femoral artery (1.5%) 4) Pulse pressure increased progressively from the ascending aorta to the femoral artery (42.8%) 5) There was significant drop (7%) of the systolic pressure of the ascending aorta compared with that of left ventricle. The results showed that the peripheral amplifications were limited to the systolic and pulse pressure, but the diastolic and mean pressure in peripheral arteries were lower than that of central artery.
Aorta
;
Aorta, Thoracic
;
Arterial Pressure*
;
Arteries
;
Blood Pressure*
;
Cardiac Catheterization
;
Cardiac Catheters
;
Child*
;
Femoral Artery
;
Heart Defects, Congenital*
;
Heart Ventricles
;
Humans
;
Iliac Artery
;
Young Adult
7.Primitive Neuroectodermal Tumor Associated with Mature Cystic Teratoma of the Ovary: A case report.
Young Ju KIM ; Mi Yeong JEON ; Mi Sun KANG ; Chan Hwan KIM
Korean Journal of Pathology 1996;30(12):1150-1154
Malignant transformation of benign cystic teratomas of the ovary is rare, with an incidence rate of 1-3%. The most common malignancy associated with benign cystic teratoma of the ovary is squamous cell carcinoma, which represents 90% of malignant transformations, followed by adenocarcinoma and carcinoid. Primary malignant neuroectodermal tumor in a mature cystic teratoma is extremely rare and microscopically can be subclassified as differentiated, primitive, and anaplatic. We experienced a case of primitive neuroectodermal tumor (PNET) associated with mature cystic teratoma of the ovary in a 11-year-old girl. Grossly, the ovary was a unilocular cyst which contained sebum material and disclosed several large, yellow to gray-tan polypoid excresences attached to the inner cystic wall. Except a large, fish-flesh, soft mass, the other polypoid masses were covered with sebum and contained small pieces of cartilage and tooth, and microscopically represented as mature teratoma. The large, fish-flesh, soft mass disclosed sheets and lobules of closely packed small cells with thin fibrovascular septa, which frequently replacing and encroaching the mature cystic teratoma. The small tumor cells were uniform and made up of round to oval nuclei with coarse chromatin and prominent nucleoli, very similar to those of PNET of the central nervous system.
Incidence
;
Cysts
;
Adenocarcinoma
8.Safety and Feasibility of Thallium-201 Myocardial SPECT with Intravenous Infusion of Disodium Sdenosine Trophosphate ( ATP ) in the Diagnosis of Coronary Artery disease.
Moon Sun PAI ; Chan H PARK ; Seok NAM ; Yoon Won KIM ; Han Soo KIM
Korean Journal of Nuclear Medicine 1998;32(3):250-258
PURPOSE: ATP (adenosine triphosphate) is a potent coronary vasodilator with a rapid onset of action and a very short half-life. Myocardial perfusion scintigraphy with intravenous ATP has not yet been sufficiently proven in the diagnosis, follow-up, and risk stratification of coronary artery disease. The purpose of this study was to evaluate the safety, feasibility and diagnostic accuracy of pharmacologic stress thallium-201 myocardial SPECT using an intravenous ATP infusion in patients with suspected coronary artery disease. MATERIALS AND METHODS: Thalliurn-201 myocardial SPECT in 319 patients with suspected coronary artery disease were performed after the infusion of ATP (0.08 mg/kg/min for 6 rnin). The adverse effects were carefully monitored. Coronary angiography was also performed within 3 weeks. RESULTS: Although 76.5% of the patients had sorne adverse effects, they were transient, mild, and well tolerated. In all patients, the ATP infusion protocol was completed and only 2 patients required aminophylline. The adverse effects were dyspnea in 63%, headache in 31%, flushing in 21%, chest pain in 14% and abdominal discomfort in 5% of the patients. The sensitivity and specificity were 80% and 90% respectively. CONCLUSION: Thallium-201 myocardial SPECT after 6 min-infusion of ATP at a rate of 0.08 mg/kg/min is safe and has a diagnostic value in detecting coronary artery disease.
Adenosine Triphosphate*
;
Aminophylline
;
Chest Pain
;
Coronary Angiography
;
Coronary Artery Disease*
;
Coronary Vessels*
;
Diagnosis*
;
Dyspnea
;
Flushing
;
Follow-Up Studies
;
Half-Life
;
Headache
;
Humans
;
Infusions, Intravenous*
;
Perfusion Imaging
;
Sensitivity and Specificity
;
Tomography, Emission-Computed, Single-Photon*
9.A Case of Complicated BPPV(Benign Paroxismal Positional Vertigo) .
Myoung Chan KIM ; Ji Sun KIM ; Yang Hee OH ; Sang Yong CHUNG ; Chung Ku RHEE
Journal of the Korean Balance Society 2004;3(1):180-183
Canalith repositioning maneuver is effective to treat benign paroxysmal positional vertigo(BPPV). This case showed complicated form of the BPPV such as changes of canalolithiasis to cupulolithiasis, involvement of one canal to two canals and from unilateral to bilateral involvement during the reposition maneuver. This patient was diagnosed as left lateral canalolithiasis at first. After left barbecue maneuver, the type was changed to the right posterior cupulolithiasis. Semont maneuver was performed and then the type of BPPV was changed to combined type with right posterior canalolithiasis and left lateral canalolithiasis. We performed left barbecue maneuver and right Epley maneuver. Then the type of BPPV was changed to left lateral cupulolithiasis. After Brandt-Daroff maneuver and left barbecue maneuver, nystagmus and dizziness disappeared finally.
Dizziness
;
Humans
10.Activity of quinolones and virulence to isolated aerobic bacteria from the intraabdominal abscess.
Chan Hoon YU ; Hee Sun KIM ; Tai Il JEON ; Sung Kwang KIM
Journal of the Korean Society for Microbiology 1991;26(3):233-240
No abstract available.
Abscess*
;
Bacteria, Aerobic*
;
Quinolones*
;
Virulence*