1.Keratosis Lichenoides Chronica with Pachyonychia Congenita-like Nail Changes.
Myung Soo CHA ; Kyeong Han YOON ; Soo Chan KIM
Annals of Dermatology 1996;8(2):164-167
A 26-year-old man presented with a 7-month history of hyperkeratotic skin lesions on both elbows and heels. He also had marked subungal hyperkeratosis and splinter hemorrhage on the finger and toe nails. A biopsy specimen from the elbow revealed lichenoid re-actions with areas of epidermal atrophy with alternating acanthosis and foci of parakeratosis. We made a diagnosis of keratosis lichenoides chronica based on the characteristic clinicopathologic findings. We have treated the patient with etretinate, but only the skin lesions on the elbows and heels responded to treatment.
Acitretin
;
Adult
;
Atrophy
;
Biopsy
;
Diagnosis
;
Elbow
;
Etretinate
;
Fingers
;
Heel
;
Hemorrhage
;
Humans
;
Keratosis*
;
Nails, Malformed*
;
Parakeratosis
;
Skin
;
Toes
2.A Granuloma Caused by Candida guilliermondii.
Young Soo HAN ; Ki Chan MOON ; Soo Nam KIM
Annals of Dermatology 1990;2(2):109-112
No abstract available.
Candida*
;
Granuloma*
3.The effects of adriamycin on twitch force and membrane potential in an isolated Guinea-pig papillary muscle.
Chan Uhng JOO ; Pyung Han HWANG ; Jung Soo KIM ; Hee Cheol YU ; Soo Wan CHAE
Journal of the Korean Pediatric Society 1991;34(5):677-681
No abstract available.
Doxorubicin*
;
Membrane Potentials*
;
Membranes*
;
Papillary Muscles*
4.Diagnosis of Xeroderma Pigmentosum by Measuring Unscheduled DNA Synthesis.
Kyu Han KIM ; Phil Soo AHN ; Jin Ho CHUNG ; Kyoung Chan PARK
Annals of Dermatology 1996;8(2):135-139
No abstract available.
Diagnosis*
;
DNA*
;
Ichthyosis*
;
Xeroderma Pigmentosum*
5.A clinical study on cardiovascular disease of children taken cardiac catheterization and cineangiography.
Gi Yeon SONG ; Seog Beom CHO ; Pyoung Han HWANG ; Chan Uhng JOO ; Jung Soo KIM
Journal of the Korean Pediatric Society 1992;35(7):949-956
No abstract available.
Cardiac Catheterization*
;
Cardiac Catheters*
;
Cardiovascular Diseases*
;
Child*
;
Cineangiography*
;
Heart Defects, Congenital
;
Humans
6.Clinicopathological correlation in endometrial carcinoma.
Byung Soo HAN ; Hak Hee LEE ; Joon SONG ; Chan Yong PARK
Korean Journal of Obstetrics and Gynecology 1992;35(4):562-570
No abstract available.
Endometrial Neoplasms*
;
Female
7.Two Cases of Bullous Pemphigoid Showing the Characteristics of Herpes Gestationis Autoantibodies.
Kyeong Han YOON ; Mi Ra YOON ; Il Joo LEE ; Soo Chan KIM
Korean Journal of Dermatology 1998;36(3):451-455
Bullous pemphigoid(BP) and herpes gestationis(HG) are subepidermal bullous diseases which show clinical and immunological similarities. Both diseases show immune deposits along the basement membrane zone and their autoantibodies bind a common antigenic site within the non-collagenous stretch of the 180 kDa BPAG2 ectodomain. Besides its association with pregnancy, HG has some characteristic features that distinguish it from BP. The serum of patients with HG often contains an IgG that avidly fixes complement, and showes IgG1 subclass predominance. We report here two cases of non-pregnant young women presenting clinical and histological features of bullous pemphigoid or herpes gestationis. The immunopathology, IgG subtyping and immunoblotting studies showed that the autoantibodies in the patients were the characteristic ones of herpes gestationis. The patients might be a subtype of BP that have characteristics of autoantibodies of HG patients.
Autoantibodies*
;
Basement Membrane
;
Complement System Proteins
;
Female
;
Humans
;
Immunoblotting
;
Immunoglobulin G
;
Pemphigoid Gestationis*
;
Pemphigoid, Bullous*
;
Pregnancy
8.A Case of Infantile Nyofibromatosis.
Sung Nam CHANG ; Tae Hyun PARK ; Kyeong Han YOON ; Soo Chan KIM
Korean Journal of Dermatology 1994;32(5):907-910
Infantile myofibromatosis is an uncommon, benign, probably hamai tomatous proliferation of myofibroblasts. This lesions are most often present before the age of 2 years, show a male predomenance and may be multiple or solitary. The solitary lesions arise in the dermis, subcutis, or deep soft tissue, most commonly in the head and neek region or trunk. The elinical coirse is benign and spontaneous regression is not infrequent. A female newborn presented with a turmr lesion on the upper portion of the right eyelid. Physical examination showed a firm, non-tender, fixed, erythematous, 3 x 3cm sized tumor. Histologic examinatign revealed a spindle cell tumor in the deimis with a whorled arrangemant and grouped fescicles. There was no evidence for potential visceval and bony involvement. Follow-up examination at 6 months of aige revealed a remarkable degree of spoitaneous involution.
Dermis
;
Eyelids
;
Female
;
Follow-Up Studies
;
Head
;
Humans
;
Infant, Newborn
;
Male
;
Myofibroblasts
;
Myofibromatosis
;
Physical Examination
9.Incidence of Sore Throat after Tracheal Intubation and Postoperative.
Gi Baeg HWANG ; Soo Il LEE ; Han Suk PARK ; Chan Jong CHUNG
Korean Journal of Anesthesiology 1997;33(3):533-539
BACKGROUND: Sore throat is one of the most common complications of intubation. There are many factors that affect the incidence of sore throat and the succinylcholine-induced myalgia. Our study is to reveal the influences of these factors on the postoperative sore throat and the succinylcholine-induced myalgia. METHODS: One thousand and seven patients in ASA class I or II undergoing elective surgery under general anesthesia were studied, except patients undergoing brain surgery, open heart surgery, operation in oro-, naso-pharynx and larynx, and uncooperated psychiatric. We checked age, sex, patient controlled analgesia and nasogastric tube, size and kind of tube, operation position, duration of intubation and anesthetic agent. At 24~38 hours after operation, the patients were questioned about pre- and postoperative sore throat, or myalgia. RESULTS: Sore throat after endotracheal intubation developed more frequently in woman (32.8%) than man (25.9%). The older the patients, the lower the incidence of sore throat (p<0.05). The longer the anesthesia duration, the lower the incidence of sore throat (p<0.05). Succinylcholine, patient controlled analgesia, nasogastric tube, endotracheal tube, operation position, maintenance anesthetic agents and the amount of smoking did not affect the incidence of sore throat. The incidence of succinylcholine-induced myalgia was lower in elderly or patients who were administered nondepolarizing muscle relaxant. CONCLUSIONS: The incidences of sore throat and myalgia were 29% and 15%, respectively. There were significant differences in incidence of sore throat and myalgia depending on the gender, age, duration of operation, but the controllable factors which reduce the incidence of sore throat were not found. Nondepolarizing muscle relaxants could reduce the occurrence of postoperative myalgia.
Aged
;
Analgesia, Patient-Controlled
;
Anesthesia
;
Anesthesia, General
;
Anesthetics
;
Brain
;
Female
;
Humans
;
Incidence*
;
Intubation*
;
Intubation, Intratracheal
;
Larynx
;
Myalgia
;
Pharyngitis*
;
Smoke
;
Smoking
;
Succinylcholine
;
Thoracic Surgery
10.Ultrastructural Study of Vitiligo.
Chan Woo JEONG ; Il Yeong SON ; Un Cheol YEO ; Joungho HAN ; Eil Soo LEE
Annals of Dermatology 2001;13(3):158-162
BACKGROUND: There is a long-standing controversy whether melanocytes in vitiligo of more than 1 year duration are actually lost or still present. Resolving this matter is essential in understanding the underlying pathology and for the development of the treatment. On previous immunohistochemical and ultrastructural studies of vitiligo lesions, damage of melanocyte and keratinocyte in early lesions were reported and complete absence of melanocyte in long standing lesions were known. OBJECTIVE: This study aimed to determine the existence of the differences in pathologic changes in melanocytes according to the duration of the lesion. METHODS: We investigated the vitiliginous skin samples from 31 patients with early(less than 1 year duration) vitiligo and 30 patients with long standing(l to 5 years duration) vitiligo under the electron microscopy. RESULTS: Multiple degenerative changes in melanocytes were observed in the early and long standing lesions. In long standing lesions, degeneration of melanocytes including pyknotic, in-dented nuclei, vacuolated cytoplasms and blunted dendrites were more pronounced than early lesions. Even in long standing lesions, definite or presumptive melanocytes were observed in 16(53.3%) of 30 cases. CONCLUSION: Our results suggest that the melanocytes of vitiligo lesions were damaged and that the percentage of degenerative changes increase in accordance with the duration of the lesion. However, in long standing lesions as well as in early lesions, some residual melanocytes can be observed ultrastructurally.
Cytoplasm
;
Dendrites
;
Humans
;
Keratinocytes
;
Melanocytes
;
Microscopy, Electron
;
Pathology
;
Skin
;
Vitiligo*