1.A Case of Classic Kaposi's Sarcoma Developing on the Face.
Joon Soo PARK ; Hyo Chan JANG ; Hyun CHUNG ; Jeong Im SIN
Korean Journal of Dermatology 2005;43(11):1576-1578
Classic Kaposi's sarcoma is a human herpesvirus-8 associated with a multicentric lymphoangioproliferative tumor primarily arising in the lower extremities, but rarely in the head and neck. We herein report a 63-year-old man with primary classic Kaposi's sarcoma on the face. He presented with asymptomatic, erythematous papules on the nasal ala which had been noticed 2 months earlier. Histopathologic examination and nested polymerase chain reaction analysis in the tissue disclosed typical features of Kaposi's sarcoma.
Head
;
Humans
;
Lower Extremity
;
Middle Aged
;
Neck
;
Polymerase Chain Reaction
;
Sarcoma, Kaposi*
2.Risk Factors of Readmission to Hospital for Pneumonia in Children.
Yu Chan HONG ; Eom Ji CHOI ; Sin Ae PARK
Pediatric Infection & Vaccine 2017;24(3):146-151
PURPOSE: We analyzed the risk factors affecting readmission of children with pneumonia. METHODS: We retrospectively analyzed the medical records of pediatric patients admitted to the Department of Pediatrics at the Jeonju Presbyterian Medical Center from January 2007 to August 2016. We classified patients who were readmitted with pneumonia within 30 days of discharge as the readmission group and patients who were admitted with pneumonia for the first time as the first admission group. RESULTS: Among 158 patients, the study (readmission) group included 82 patients and the control (first admission) group included 76 patients. Age, the percentage of segmented neutrophils and lymphocytes, the number of admissions in the last 12 months, the associated diseases (respiratory diseases such as asthma), and the affection of the right upper lung were analyzed as risk factors for readmission. However, based on a regression analysis, only age and associated diseases were found to be significant risk factors. The rate of readmission increased with younger age. When there were associated diseases, the rate of readmission also increased. CONCLUSIONS: Young age and associated diseases were significant risk factors for readmission for patients with pediatric pneumonia. When pediatric patients are admitted with pneumonia, if they are young and/or have associated diseases, a comprehensive approach is needed to reduce the rate of readmission with careful consideration of precise examination, treatment, timing of discharge, and follow-up.
Child*
;
Follow-Up Studies
;
Humans
;
Jeollabuk-do
;
Lung
;
Lymphocytes
;
Medical Records
;
Neutrophils
;
Patient Readmission
;
Pediatrics
;
Pneumonia*
;
Protestantism
;
Retrospective Studies
;
Risk Factors*
3.Risk Factors of Readmission to Hospital for Pneumonia in Children.
Yu Chan HONG ; Eom Ji CHOI ; Sin Ae PARK
Pediatric Infection & Vaccine 2017;24(3):146-151
PURPOSE: We analyzed the risk factors affecting readmission of children with pneumonia. METHODS: We retrospectively analyzed the medical records of pediatric patients admitted to the Department of Pediatrics at the Jeonju Presbyterian Medical Center from January 2007 to August 2016. We classified patients who were readmitted with pneumonia within 30 days of discharge as the readmission group and patients who were admitted with pneumonia for the first time as the first admission group. RESULTS: Among 158 patients, the study (readmission) group included 82 patients and the control (first admission) group included 76 patients. Age, the percentage of segmented neutrophils and lymphocytes, the number of admissions in the last 12 months, the associated diseases (respiratory diseases such as asthma), and the affection of the right upper lung were analyzed as risk factors for readmission. However, based on a regression analysis, only age and associated diseases were found to be significant risk factors. The rate of readmission increased with younger age. When there were associated diseases, the rate of readmission also increased. CONCLUSIONS: Young age and associated diseases were significant risk factors for readmission for patients with pediatric pneumonia. When pediatric patients are admitted with pneumonia, if they are young and/or have associated diseases, a comprehensive approach is needed to reduce the rate of readmission with careful consideration of precise examination, treatment, timing of discharge, and follow-up.
Child*
;
Follow-Up Studies
;
Humans
;
Jeollabuk-do
;
Lung
;
Lymphocytes
;
Medical Records
;
Neutrophils
;
Patient Readmission
;
Pediatrics
;
Pneumonia*
;
Protestantism
;
Retrospective Studies
;
Risk Factors*
4.Comparison of Thiopental Sodium and Propofol as to the Effects of Anesthesia Induction and Hemodynamic Changes to Endotracheal Intubation.
Myung Ha YOON ; Chan Jin PARK ; Young Sin HAN
Korean Journal of Anesthesiology 1995;28(5):626-633
The purpose of this study is to compare thiopental sodium and propofol as to the effects of anesthesia induction and hemodynamic changes associated with endotracheal intubation. Forty healthy adult patients, scheduled for elective surgery under general anesthesia, were randomly assigned to receive either thiopental sodium 5 mg/kg (Group 1, n =20) or propofol 2 mg/kg (Group 2, n=20) as an induction agent. Endotracheal intubation was performed following injection of succinylcholine 1 mg/kg. Anesthesia was maintained with 1.5~2% ethrane and 50% N2O in O2. The results were as follows, 1) Both thiopental sodium and propofol revealed high incidence of pain in the site of injection (13/20, 10/20, respectively). 2) The time from the start of injection to spontaneous closing of eyes and to loss of eyelid reflex were 42 and 43 sec in group 1 and 46 and 51 sec in group 2, respectively. 3) The loss of respiratory efforts. Occured in all cases and took 65 and 59 sec, in group 1 and 2 respectively. 4) The blood pressure was more decreased in group 2 than group 1 during induction period, but there was no significant difference between two groups. Also, there was no significant difference of the heart rate between two groups. 5) The increments of systolic blood pressure and rate-pressure-product to endotrachal intubation in group 2 were less than group 1 at time of immediate and 1 minute after intubation. Also, the increments of mean arterial pressure, disastolic blood presure and heart rate were lessen in group 2 than group 1. The retum of blood pressure, heart rate and RPP to the control was fasten in group 2 than group l. In conclusion, propofol may be an alternative to thiopental sodium in patients who require endotracheal intubation without hemodynamic instability.
Adult
;
Anesthesia*
;
Anesthesia, General
;
Arterial Pressure
;
Blood Pressure
;
Enflurane
;
Eyelids
;
Heart Rate
;
Hemodynamics*
;
Humans
;
Incidence
;
Intubation
;
Intubation, Intratracheal*
;
Propofol*
;
Reflex
;
Succinylcholine
;
Thiopental*
5.The Effect of Nutrition Education Program in Physical Health, Nutritional Status and Health-Related Quality of Life of the Elderly in Seoul.
Yoonjung CHOI ; Chan KIM ; Yoo Sin PARK
The Korean Journal of Nutrition 2007;40(3):270-280
This study was performed to investigate the effects of nutrition education program in physical health, nutritional status and health-related quality of life (HRQoL )of the Elderly in Seoul. Nutrition education program was consisted of healthy eating, prevention and diet therapy of obesity, diabetes, cardiovascular disease, and osteoporosis. Seventy eight free-living elderly people (13 male, 65 female ), aged > or =60 years participated in this program. Before and after nutri-tion education program, we surveyed the general characteristics, physical health, general health, nutrition status, and health-related quality of life to the subjects. All the subjects were divided into program completers (N =47 )and non-completers (N =31 ). All the data were analyzed by student t-test, chi-square test, paired t-test, and marginal homo-geneity test using SPSS 9.0 version at p <0.05. After nutrition education program, physical activity and ADL maintained, however IADL improved in program noncompleters. In eating habits, 'slow eating' significantly improved in program completers in program completers. Nutrition knowledge and recognition scores were significantly increased in both groups, and accuracy score was significantly increased in program completers. However, nutrient-intakes of %RDA were not significantly changed in both groups, and it seemed to be more influenced by other factors such as 'family income' or 'family type' than by the nutrition education program. In HRQoL, social functioning was improved after nutrition education program in both groups (p <0.05 ). The nutrition education program has more effects on the pro-gram completers than on the noncompleters, and it is also needed social supports for the Elderly to fulfill their nutrient requirements.
Activities of Daily Living
;
Aged*
;
Cardiovascular Diseases
;
Diet Therapy
;
Eating
;
Education*
;
Female
;
Humans
;
Male
;
Motor Activity
;
Nutritional Status*
;
Obesity
;
Osteoporosis
;
Quality of Life*
;
Seoul*
6.Abdominal Pregnancy Presenting as Massive Lower Gastrointestinal Bleeding.
Man Woo KIM ; Sin Hee PARK ; Sang Yong CHOI ; Guk Hyun BAE ; Ho Sung KIM ; Kwang Chan LEE ; Chin Seung KIM
Journal of the Korean Surgical Society 2004;67(4):338-341
An ectopic pregnancy in the abdominal organs is very rare. Primary intestinal pregnancy is considered the rarest form of extrauterine pregnancy, and only a few well-documented cases have been reported. Herein, a case of an abdominal pregnancy in a 25-year-old woman, with massive lower gastrointestinal bleeding, is reported. The source of bleeding could not be identified, despite gastroscopy, ultrasonography and angiography investigations. A diagnostic laparotomy disclosed an abdominal pregnancy, causing an erosion of the jejunal wall at the site of the pregnancy, with massive lower gastrointestinal bleeding. An abdominal pregnancy is seldom included in the differential diagnosis of lower gastrointestinal bleeding. The possibility of intestinal erosion in an abdominal pregnancy should be borne in mind in cases of lower gastrointestinal bleeding.
Adult
;
Angiography
;
Diagnosis, Differential
;
Female
;
Gastroscopy
;
Hemorrhage*
;
Humans
;
Laparotomy
;
Pregnancy
;
Pregnancy, Abdominal*
;
Pregnancy, Ectopic
;
Ultrasonography
7.Prognostic Value of Apoptosis in Breast Cancer.
Ho Suck SONG ; Dae Sung YOON ; Chan Heun PARK ; Eun Sook NAM ; Hyung Sick SIN
Journal of the Korean Surgical Society 1998;55(4):492-497
The aim of this study was to determine if the apoptotic degree could predict the prognosis for breast cancer in mastectomy specimens and to establish if any association existed between the apoptotic degree and clinical variables such as age, size, hormone receptor, lymph node metastasis, stage, result of follow up. The apoptotic degree, defined as the number of morphologically identified apoptotic bodies in the view of a 200X microscope, was calculated for 59 breast cancers. We applied an immunohistochemical procedure for staining the apoptotic cells in parapin sections of 59 breast cancers. The histochemical method used for the analysis of apoptosis was based on the detection of DNA breaks by terminal transferase-mediated in situ end labeling (TUNEL). The results were as follows; 1. An association between apoptotic degree and age was demonstrable (p=0.050). 2. No association between apoptotic degree and tumor size was demonstrable. 3. No association between apoptotic degree and lymph node metastasis was demonstrable. 4. An association between apoptotic degree and stage was demonstrable. 5. No association between apoptotic degree and hormone receptor was demonstrable (p=0.023). 6. No association between apoptotic degree and follow up results was demonstrable, however a low apoptotic degree showed a tendency for a poor clinical outcome, and this result had partiall statistical significance. Thus provisionally its value as an independent prognostic index has yet to be established and demands more study.
Apoptosis*
;
Breast Neoplasms*
;
Breast*
;
DNA Breaks
;
Follow-Up Studies
;
Lymph Nodes
;
Mastectomy
;
Neoplasm Metastasis
;
Prognosis
8.The Effect of Corpus Callosotomy in the Lithium-Pilocarpine Induced Status Epileptic Rats.
Sin Soo JEUN ; Yung Gil HONG ; Chun Kun PARK ; Mun Chan KIM ; Chang Rak CHOI ; Joon Ki KANG
Journal of Korean Neurosurgical Society 1999;28(5):603-611
Section of the corpus callosum(SCC) is a useful surgical therapy in selected types of epilepsy, i.e., tonic, atonic, and intractable generalized convulsive seizures. The object of this study was to determine effect of SCC on behaviors, electroencephalography(EEG) and Fos expression in the lithium-pilocarpine model of status epilepticus in the rat. A total of 40 Sprague-Dawley rats were used. They were divided into two groups: control and lesioned group, 20 rats for each. The control group had no callosal section and was injected with lithium-pilocarpine. The lesioned group had callosal section before lithium-pilocarpine injection. In each group, ten rats were used for behavior and EEG monitoring and other 10 were used for Fos expression. The results were as follows: 1) In the SCC group, four(40%) rats never developed status epilepticus, among them two(20%) never exhibited any seizure, while all of the control group developed seizure and status epilepticus. None of the SCC animals died until 24 hours after lithium-pilocarpine injection but 70% of the control animals died within 24 hours of status epilepticus. This difference was statistically significant(p<0.05). 2) The mean latency to the first seizure, status epilepticus and periodic epileptiform discharges after lithium-pilocarpine injection were 34.7+/-2.6min, 32.3+/-1.8min and 180.4+/-9.8min, respectively, in the SCC group, while was 21.0+/-2.0min, 58.2+/-6.9min and 215.6+/-7.2min, respectively, in the control group. These latencies were significantly longer than in the control group(p<0.05). 3) There was a massive Fos expression on the cerebral cortex in the control group at 4 hours after lithiumpi-locarpine injection , while it was less in the SCC group. This difference was statistically significant(p<0.05). In conclusion, complete corpus callosotomy had contributed to the protective effect on the development of status epilepticus in the lithium-pilocarpine model which was similar to that observed in humans. And result of Fos expression suggest that Fos immunohistochemisty may be useful in the study of seizure pathways as a metabolic marker in the lithium-pilocarpine model.
Animals
;
Cerebral Cortex
;
Electroencephalography
;
Epilepsy
;
Humans
;
Rats*
;
Rats, Sprague-Dawley
;
Seizures
;
Status Epilepticus
9.Erratum: Correction of Nomenclature of BRAF Mutation.
Uiju CHO ; Woo Jin OH ; Ja Seong BAE ; Sohee LEE ; Young Sub LEE ; Gyeong Sin PARK ; Youn Soo LEE ; Chan Kwon JUNG
Journal of Korean Medical Science 2014;29(10):1439-1439
We made a mistake in our recently published article.
10.Serum lipid level and risk factor analysis of hypercholesterolemia during continuous ambulatory peritoneal dialysis.
Heung Soo KIM ; Ki Yong KIM ; Chan Sin PARK ; Han Sun CHO ; Kyu Hun CHOI ; Sung Kyu HA ; Ho Young LEE ; Dae Suk HAN ; Moon Jae KIM
Korean Journal of Nephrology 1992;11(4):417-426
No abstract available.
Hypercholesterolemia*
;
Peritoneal Dialysis, Continuous Ambulatory*
;
Risk Factors*