1.Expression of E-cadherin in Experimental Bladder Carcinogenesis Induced by N-butyl-n-4-hydroxybutyl Nitrosamine.
Yun Chan CHOI ; Eun Sik LEE ; Won Hee PARK
Korean Journal of Urology 2000;41(7):838-843
No abstract available.
Cadherins*
;
Carcinogenesis*
;
Urinary Bladder*
2.Multilocular Cystic Renal Cell Carcinoma: A case report.
Ki Jung YUN ; Weon Cheol HAN ; Chan CHOI ; Hyung Bae MOON ; Joung Sik RIM
Korean Journal of Pathology 1992;26(3):314-316
Multilocular cystic renal cell carcinoma appears to be a distinct and rare subtype of renal cell carcinoma with characteristic gross and microscopic features. Multilocular cystic renal cell carcinoma should be separated from multilocular cyst, multilocular cystic nephroma, and renal cell carcinoma with cystic degeneration. We present a case of multilocular cystic renal cell carcinoma. A 61-year-old man presented with right flank pain for 4 years. The computerized tomography revealed multilocular cystic mass in the upper pole of right kidney. The cystic mass measured 4.5x4 cm. The cyst was multilocular and locules not communicated with each other. The solid area was not present. Microscopically, the locules were lined by flat or cuboidal neoplastic clear cells. The clear cells were focally aggregated in the septa. The nephron was not present in the septa.
Male
;
Humans
;
Cysts
3.Clinical Significance of Double Contrast Arthrography
Key Yong KIM ; Duk Yun CHO ; Chan Il PARK ; Jae Gon SEO ; Jun Sik PARK
The Journal of the Korean Orthopaedic Association 1977;12(4):673-679
Double contrast arthrography has been widely accepted as a method to diagnose the internal derangement of the knee. It is a safe and technically simple procedure permitting accurate diagnosis of lesions of the menisci. In 20 cases operated upon, with the diagnosis of internal derangement of the knee, we performed double contrast arthrography before surgery. We analysed the cases concerning the diagnostic accuracy of arthrography, its clinical significance and discrepancies between arthrographic findings and postoperative lesions. The results were as follows: 1. The cases consisted of 16 cases of meniscal lesion, 4 cases of ligamentous lesion and 3 cases of loose body. 2. In the meniscal lesions, 14 of the 16 cases (87.5%) were diagnosed accurately by arthrography, Therefore arthrography was more useful in diagnosing meniscal lesions as compared with clincal symptoms (69%). 3. In cases of ligamentous lesions arthrography was not significant-ly helfpful, in contrast clinical signs afforded important clues. 4. We encountered 1 case of false positive and 1 case of false negative.
Arthrography
;
Diagnosis
;
Knee
;
Ligaments
;
Methods
4.The Correlation between the Degree of Enophthalmos and the Extent of Fracture in Medial Orbital Wall Fracture Left Untreated for Over Six Months: A Retrospective Analysis of 81 Cases at a Single Institution.
Yun Sik SUNG ; Chan Min CHUNG ; In Pyo HONG
Archives of Plastic Surgery 2013;40(4):335-340
BACKGROUND: In patients with medial orbital wall fracture, predicting the correlation between the degree of enophthalmos and the extent of fracture is essential for deciding on surgical treatment. We conducted this retrospective study to identify the correlation between the two parameters. METHODS: We quantitatively analyzed the correlation between the area of the bone defect and the degree of enophthalmos on computed tomography scans in 81 patients with medial orbital wall fracture who had been left untreated for more than six months. RESULTS: There was a significant linear positive correlation between the area of the medial orbital wall fracture and the degree of enophthalmos with a formula of E=0.705A+0.061 (E, the degree of enophthalmos; A, the area of bone defect) (Pearson's correlation coefficient, 0.812) (P<0.05). In addition, that there were no cases in which the degree of enophthalmos was greater than 2 mm when the area of the medial orbital wall fracture was smaller than 1.90 cm2. CONCLUSIONS: Our results indicate not only that 2 mm of enophthalmos corresponds to a bone defect area of approximately 2.75 cm2 in patients with medial orbital wall fracture but also that the degree of enophthalmos could be quantitatively predicted based on the area of the bone defect even more than six months after trauma.
Decision Support Systems, Clinical
;
Enophthalmos
;
Humans
;
Orbit
;
Orbital Fractures
;
Retrospective Studies
5.Acute myelogenous leukemia following etoposide and cisplatin combination chemotherapy for small cell carcinoma of the lung.
Jin Ki PAEK ; Chan Wook PARK ; Jee Yun LEE ; Jong Ho WON ; Dae Sik HONG ; Hee Sook PARK
Korean Journal of Hematology 1992;27(1):123-127
No abstract available.
Carcinoma, Small Cell*
;
Cisplatin*
;
Drug Therapy, Combination*
;
Etoposide*
;
Leukemia, Myeloid, Acute*
;
Lung*
6.Small hepatocellular carcinoma; treatment with subsegmental intrahepatic arterial injection of radioliodinated fatty acid ester.
Hyung Sik YOO ; Jong Tae LEE ; Ki Whang KIM ; Chang Yun PARK ; Byung Soo KIM ; Heung Jai CHOI ; Kyong Sik LEE ; Chan Il PARK
Journal of the Korean Cancer Association 1992;24(3):411-421
No abstract available.
Carcinoma, Hepatocellular*
7.Extralobar Pulmonary Sequestration located in Right Oblique Fissure with Unusual Vascularture.
Chan Sik YUN ; Jae il JUNG ; Jae Wuk KIM ; Young Chul YUN ; Hong Sup LEE ; Hye Kyung LEE
The Korean Journal of Thoracic and Cardiovascular Surgery 2001;34(6):502-505
Pulmonary sequestration is an abnormal lung tissue that does not communicate with tracheobronchial tree, and that receives blood supply from anomalous arteries. Pulmonary sequestration is divided into two anatomical forms, intralobar and extralobar. Extralobar pulmonary sequestration is usually located between the diaphragm and the lower lobe and has systemic arterial supply and venous drainage, and most patients are diagnosed in their infancy. We report an extralobar pulmonary sequestration located between the right upper lobe and the lower lobe in a 48-year-old female adult, which has anomalous blood supply from the right pulmonary artery and venous drainage directly into the left atrium.
Adult
;
Arteries
;
Bronchopulmonary Sequestration*
;
Diaphragm
;
Drainage
;
Female
;
Heart Atria
;
Humans
;
Lung
;
Middle Aged
;
Pulmonary Artery
8.Pharmacokinetics of Dehydroevodiamine Following Intravenous Administration in Rats.
Seong Yun KIM ; Chan Soo MOON ; Yun Sik CHOI ; Sang Bok LEE
The Korean Journal of Physiology and Pharmacology 2004;8(1):65-67
Dehydroevodiamine (DHED) is one of the bioactive components of the Chinese herbal medicine Wu-chu-yu-tang that has been shown to produce various pharmacological effects. In the present study, we investigated the pharmacokinetics of DHED after intravenous administration of two doses (2.5 and 5 mg/kg) in anesthetized rats. The plasma concentration of DHED was measured by reverse-phase high-performance liquid chromatography with UV detection. The mean area under the curve of the time-concentration profile was 21.9 and 53.9 microgram-min/ml after the 2.5- and 5-mg/kg doses, respectively, and the volume of distribution was 1584.9 and 1580.6 ml following 2.5- and 5-mg/kg doses, respectively. Plasma concentration profiles versus time were compatible with a two-compartment model and first-order kinetics. The terminal elimination half-life was 91.8+/-16.6 min and 78.7+/-11.9 min in the dose of 2.5 and 5 mg/kg, respectively. This is the first report to study the pharmacokinetics of DHED in animals.
Administration, Intravenous*
;
Animals
;
Asian Continental Ancestry Group
;
Chromatography, High Pressure Liquid
;
Chromatography, Liquid
;
Half-Life
;
Herbal Medicine
;
Humans
;
Injections, Intravenous
;
Kinetics
;
Pharmacokinetics*
;
Plasma
;
Rats*
9.Aortoesophageal Fistula after Prosthetic Patch Aortoplasty for Mycotic Aneurysm of the Descending Thoracic Aorta.
Hong Sup LEE ; Jae Wuk KIM ; Jae Il JUNG ; Chan Sik YUN ; Sun Hun LEE ; Young Chul YOON ; Bon Il KU ; Chang Ho KIM
The Korean Journal of Thoracic and Cardiovascular Surgery 2000;33(10):839-842
Aortoesophageal fistula is an uncommon and fatal complication after surgery of aortic aneurysm. A case of aortoesophageal fistula as a complication of synthetis patch aortoplasty for mycotic aneurysm of descending thoracic aorta is described. After 3 months since patch aortoplasty for mycotic aneurysm of descending thoracic aorta this patient visited the emergency room due to melena and hematemesis. After gastrofiberoscopy and computed tomography the patient was taken ot the operating room. The surgical intervention was performed in two steps. Median sternotomy and midline laparotomy were made. Hemashield's Dacron(16mm) bypass between ascending thoracic aorta and infra-renal abdominal aorta was established first. Through the posterolateral thoracotomy false aneurysm and previous Hemashield's Dacron patch of descending aorta were resected. The two ends of the aorta were sutured and esophageal fistula was repaired. The esophageal suture line and the stumps were covered with omental graft. Thirty months later the patient has had no difficulty referable to the aortic surgery.
Aneurysm, False
;
Aneurysm, Infected*
;
Aorta
;
Aorta, Abdominal
;
Aorta, Thoracic*
;
Aortic Aneurysm
;
Emergency Service, Hospital
;
Esophageal Fistula
;
Fistula*
;
Hematemesis
;
Humans
;
Laparotomy
;
Melena
;
Operating Rooms
;
Polyethylene Terephthalates
;
Sternotomy
;
Sutures
;
Thoracotomy
;
Transplants
10.Comparison of Short-term Surgical Outcomes of Ahmed Glaucoma Valve Implant between 96 mm2 and 184 mm2 of the Surface Area.
Sang Joon OH ; In Sik KIM ; Young Jae HONG ; Gong Jae SEONG ; Chan Yun KIM
Journal of the Korean Ophthalmological Society 2004;45(11):1872-1879
PURPOSE: To compare the short-term surgical outcomes of Ahmed glaucoma valve implant with a surface area between 96 mm2 and 184 mm2. METHODS: The outcomes of thirteen eyes of 13 patients with refractory glaucoma who had undergone 96 mm2-sized Ahmed glaucoma valve implantation were compared with those of 13 eyes of 13 patients with 184 mm2-sized Ahmed glaucoma valve implantation. RESULTS: Average age and preoperative intraocular pressure (IOP) were statistically indistinguishable between the two groups (p=0.54 and 0.40, respectively). Average follow-up period and final IOP were also statistically similar (p=0.15 and 1.00, respectively). Comparing the overall IOPs and the numbers of antiglaucoma medications, the IOP of postoperative day 1 with the 184 mm2-group was only relatively lower (p=0.07). The 2-year success rates were 18.0% for the 96 mm2-group and 69.2% for the 184 mm2-group (Ed-there is no respective comparison here) with Kaplan-Meier survival analysis (p=0.0018). The rates of complications and re-operation were similar between the two groups. CONCLUSIONS: The average postoperative IOPs were not statistically different between the two groups. However, the success rate was better in the 184 mm2-group than in the 96 mm2-group.
Follow-Up Studies
;
Glaucoma*
;
Humans
;
Intraocular Pressure