1.Malignant Glomus Tumor Arising in Benign Glomus Tumor.
Seung Sam PAIK ; Eun Sun KIM ; Young Chun MOON ; Chan Kum PARK ; Moon Hyang PARK ; Jung Dal LEE
Korean Journal of Pathology 1997;31(3):280-283
The glomus tumor is a distinct neoplasm composed of modified perivascular smooth-muscle cells identical to those described in the glomus body. Malignant glomus tumor, also referred to as glomangiosarcoma, is exceedingly rare. It has been subdivided into locally infiltrative glomus tumor, glomangiosarcoma arising in a benign glomus tumor, and glomangiosarcoma arising in de novo. A few cases of malignant glomus tumor arising in a benign glomus tumor have been reported. A 55-year-old man underwent resection of a solitary nodule in the right shoulder area. The tumor was biphasic with a typical benign glomus tumor at the periphery and the central sarcomatous area composed of oval to elongated pleomorphic cells with a single prominent nucleolus and occasional mitotic figures. Both tumor components showed intense staining for vimentin, smooth muscle actin, and muscle specific actin. Herein, we report a case of a malignant glomus tumor arising in a benign glomus tumor with an immunohistochemical study and a review of literatures.
Actins
;
Glomus Tumor*
;
Humans
;
Middle Aged
;
Muscle, Smooth
;
Shoulder
;
Vimentin
2.Non-Hodgkin's Lymphoma of the Uterine Cervix: 3 cases report.
Chan Pil PARK ; Young Hyeh KO ; Jung Dal LEE ; Moon Il PARK ; Kyung Tai KIM ; Sam Hyun CHO
Korean Journal of Pathology 1995;29(3):368-373
Three patients with primary non-Hodgkin's lymphoma of the uterine cervix are reported and the literature is reviewed. All the three patients in the current study presented with vaginal bleeding. They were found to have diffuse large cleaved cell lymphoma, one of which was multilobated variant with marked sclerosis. Histologically, differential diagnsis from undifferentiated small cell carcinoma, endometrial stromal sarcoma & other sarcomas was difficult and requires special stains including immunobistochemical study. Vaginal pap smears were diagnosed as 'class V; malignant lymphoma' in only one patient. Immunologically, two cases were beta-cell lineage and one case was T-cell lineage. All the patients were treated with chemotherapy only and showed good responses.
3.The Effect of Uterine Environment during Peri-implantation Period on theUltrastructure of Zona Pellucida in Mouse Oocytes and Embryos.
Sungwon HAN ; Ho Sam CHUNG ; Hee Gyoo KANG ; Ho Joon LEE ; Myung Chan GYE ; Sung Rye KIM ; Moon Kyoo KIM
Korean Journal of Fertility and Sterility 1999;26(3):345-354
In the studies on the hatching mechanisms in mammals, many investigators focused on the embryonic intrinsic factor(s) in in vitro culture, but the uterine environment as the extrinsic factor(s) is thought to play an important role in hatching mechanism. Therefore, to evaluate the effect of uterine environment on the hatching event in vivo, the immature(GV) and ovulated(MII) oocytes, and the late 2-cell embryos of mouse were transferred to pseudopregnant foster mother's uterus during peri-implantation period. So it was verified whether there would happen hatching by only uterine environment independently on embryonic stage. The ultrastructural changes of the zona surface of transferred group were compared with those of in vivo and vitro group by SEM. 36 hrs after transfer, the immature and ovulated oocytes almost degenerated, and the late 2-cell embryos developed to various embryonic stages. However, the embryos which didn't develop to blastula stage did not hatch. The ultrastructural network of ZP in transferred group seemed to be smoothed uniformly, which was different from in vitro group. In conclusion, it is suggested that the uterine environment during peri-implantation period enhances the embryo hatching by provoking the structural change of ZP.
Animals
;
Blastula
;
Embryonic Structures*
;
Herpes Zoster*
;
Humans
;
Mammals
;
Mice*
;
Oocytes*
;
Research Personnel
;
Uterus
;
Zona Pellucida*
4.Arthroscopic Repair for Traumatic Peripheral Tear of Triangular Fibrocartilage Complex.
Seung Ju JEON ; Chan Sam MOON ; Ho Seung JEON ; Haeng Kee NOH ; Sung Hwan KIM
Journal of the Korean Fracture Society 2007;20(4):330-334
PURPOSE: To assess the results of an arthroscopic repair for traumatic peripheral tears of triangular fibrocartilage complex (TFCC, Palmer type Ib). MATERIALS AND METHODS: 10 patients with traumatic peripheral TFCC tear were treated with outside-in technique with arthroscope and evaluated with an average follow-up of 19 months (range, 15 to 28 months). The clinical outcomes were assessed with investigation of pain, range of motion, grip strength, return to job and patient's satisfaction. RESULTS: The arthroscopic repair of traumatic peripheral TFCC tear resulted in significant pain relief and increase in functional ability of wrist, that is, 8 excellent, 1 good and 1 fair results. At last follow-up, the average of flexion was 79° (range 76~86°), average of extension was 78° (range 70~84°), average pronation was 85° (range 75~91°) and average supination was 87° (range 79~92°). Nine patients except one were back to their original job. CONCLUSION: Arthroscopic repair of traumatic peripheral TFCC tear could be used for pain relief and increase in functional ability of wrist.
Arthroscopes
;
Follow-Up Studies
;
Hand Strength
;
Humans
;
Pronation
;
Range of Motion, Articular
;
Supination
;
Tears*
;
Triangular Fibrocartilage*
;
Wrist
5.Arthroscopic Repair for Traumatic Peripheral Tear of Triangular Fibrocartilage Complex.
Seung Ju JEON ; Chan Sam MOON ; Ho Seung JEON ; Haeng Kee NOH ; Sung Hwan KIM
Journal of the Korean Fracture Society 2007;20(4):330-334
PURPOSE: To assess the results of an arthroscopic repair for traumatic peripheral tears of triangular fibrocartilage complex (TFCC, Palmer type Ib). MATERIALS AND METHODS: 10 patients with traumatic peripheral TFCC tear were treated with outside-in technique with arthroscope and evaluated with an average follow-up of 19 months (range, 15 to 28 months). The clinical outcomes were assessed with investigation of pain, range of motion, grip strength, return to job and patient's satisfaction. RESULTS: The arthroscopic repair of traumatic peripheral TFCC tear resulted in significant pain relief and increase in functional ability of wrist, that is, 8 excellent, 1 good and 1 fair results. At last follow-up, the average of flexion was 79° (range 76~86°), average of extension was 78° (range 70~84°), average pronation was 85° (range 75~91°) and average supination was 87° (range 79~92°). Nine patients except one were back to their original job. CONCLUSION: Arthroscopic repair of traumatic peripheral TFCC tear could be used for pain relief and increase in functional ability of wrist.
Arthroscopes
;
Follow-Up Studies
;
Hand Strength
;
Humans
;
Pronation
;
Range of Motion, Articular
;
Supination
;
Tears*
;
Triangular Fibrocartilage*
;
Wrist
6.Effect of Shifting from Combination Therapy to Monotherapy of alpha-Blockers or 5alpha-Reductase Inhibitors on Prostate Volume and Symptoms in Patients with Benign Prostatic Hyperplasia.
Hyoung Woo KIM ; Dae Geun MOON ; Hyun Min KIM ; Jong Ho HWANG ; Soon Chan KIM ; Sam Geuk NAM ; Jun Tag PARK
Korean Journal of Urology 2011;52(10):681-686
PURPOSE: Combination therapy of alpha-blockers and 5alpha-reductase inhibitors (5-ARIs) is widely used for the treatment of benign prostatic hyperplasia (BPH). We aimed to study the effect on prostate volume and symptoms of shifting to monotherapy in patients who previously received a combination therapy. MATERIALS AND METHODS: A prospective study was conducted of 60 patients who were diagnosed with BPH. Patients were aged 45 years or older and had a prostate volume of 30 cc or more, International Prostate Symptom Score (IPSS) of 12 or above, maximal flow rate (Qmax) of 15 ml/s or less, and prostate-specific antigen (PSA) level of less than 10 ng/ml. The patients initially received a combination therapy of doxazosin 4 mg/day and finasteride 5 mg/day for 3 months and were then randomly assigned to receive monotherapy for 3 months. The factors were then compared. RESULTS: A total of 30 patients were assigned to doxazosin (group 1) and 30 to finasteride (group 2) after the combination therapy. The percentage changes in prostate volume, IPSS, and Qmax during the period from post-combination therapy to post-monotherapy were not significantly different between the two groups (p=0.052, 0.908, 0.081), whereas PSA significantly decreased in group 2 (p<0.001). IPSS was not significantly different at post-combination therapy and at post-monotherapy in both groups (p=0.858, 0.071). The prostate volume significantly increased from 40.97 cc at post-combination therapy to 44.29 cc at post-monotherapy in group 1 (p=0.001) and insignificantly increased from 38.32 cc to 38.61 cc in group 2 (p=0.696). CONCLUSIONS: Although the duration of drug administration was short in this study, 5-ARI monotherapy could maintain the alleviated symptoms and reduce the risk of acute urinary retention and surgery due to prostate regrowth in BPH patients whose symptoms improved with combination therapy.
Adrenergic alpha-Antagonists
;
Aged
;
Doxazosin
;
Finasteride
;
Humans
;
Prospective Studies
;
Prostate
;
Prostate-Specific Antigen
;
Prostatic Hyperplasia
;
Urinary Retention
7.Surgical Treatment of Symptomatic Accessory Navicular in Adolescent.
Jong Min KIM ; Sung Hoon JUNG ; Byeong Mun PARK ; Chan Sam MOON ; Kil Hyeong LEE
Journal of Korean Foot and Ankle Society 2010;14(1):36-40
PURPOSE: To investigate the results of surgical treatment of the symptomatic accessory navicular in adolescent. MATERIALS AND METHODS: 11 patients who were 11~16 years old with symptomatic accessory navicular were identified between 2001 and 2009. Six cases were diagnosed after trauma and 8 cases were diagnosed by accident with painful bony protrusion on medial aspect of foot. In cases after at least 3 months of ineffective conservative treatment, patients were treated by resection of accessory navicular and reattachment of tibialis posterior tendon to the apex of the medial longitudinal arch using periosteum and ligamentous soft tissue without transposition of its course. And then short leg cast was applied for correction of the flat foot (if it is combined) which was molded into the longitudinal arch with the talonavicular joint released and foot inverted during about 6 weeks. RESULTS: All were type II accessory navicular without tibialis posterior tendon lesions. In most cases pain was improved, results were excellent in seven and good in four. Calcaneal pitch angle and talus-first metatarsal angle was improved about 4.64degrees and 5.79degrees in average. CONCLUSION: Symptomatic accessory navicular in adolescent might not be associated with the tibialis posterior tendon lesions. The surgical treatment composed of excision of the accessory navicular with simple replication of the tibialis posterior tendon without altering its course led to good results in most cases. The procedure has a low rate of complications. And it is easy to be performed with a good satisfaction.
Adolescent
;
Flatfoot
;
Foot
;
Fungi
;
Humans
;
Joints
;
Leg
;
Ligaments
;
Metatarsal Bones
;
Periosteum
;
Tendons
8.Comparison of Surgical Outcomes of Percutaneous K-Wire Fixation in Bony Mallet Fingers with Use of Towel Clip versus 18-Gauge Needle.
Ho Seung JEON ; Chan Sam MOON ; Seo Goo KANG ; Kyeong Seop SONG ; Uk Hyun CHOI
Journal of the Korean Society for Surgery of the Hand 2013;18(1):1-8
PURPOSE: The purpose was to describe comparative analysis of the surgical outcome of percutaneous K-wire fixation of bony mallet fingers reduced with towel clip and 18-gauge needle. METHODS: We analyzed the bony mallet finger patients with more than twelve months follow-up after percutaneous K-wire fixation. The patients were randomly divided into two groups. Eighteen fingers were treated with closed reduction using towel clip and 18 other fingers were treated with closed reduction using 18-gauge needle. RESULTS: Radiographs showed bony union and no subluxation in all cases after K-wire removal. The average extension lag was 2.8degrees/1.9degrees, and range of motion of distal interphalangeal joint was 70.3degrees/75degrees respectively. According to Crawford's criteria, excellent results were obtained in 9/11 fingers, good results in 8/7 fingers, and poor result in 1/0 finger, respectively. CONCLUSION: 18-gauge needle reduction in percutaneous K-wire fixation is considered less invasive and useful method for treatment of bony mallet finger with comparable results with towel clip reduction.
Fingers
;
Follow-Up Studies
;
Humans
;
Joints
;
Needles
;
Range of Motion, Articular
9.Treatment of Metacarpal Shaft Fractures with Retrograde Intramedullary Kirschner-Wire Fixation.
Chan Sam MOON ; Ho Seung JEON ; Seung Ju JEON ; Young Ray SEO ; Haeng Kee NOH
Journal of the Korean Society for Surgery of the Hand 2010;15(1):1-7
PURPOSE: The purpose of this study is to evaluate the clinical results of retrograde intramedullary fixation of metacarpal shaft fractures using two pre-bent Kirschner wires. MATERIALS AND METHODS: Between March 2006 and May 2008, 19 cases (17 patients) of metacarpal shaft fractures were treated with the retrograde intramedullary Kirschner-wire fixation and followed at least one year. The exclusion criteria were thumb metacarpal fractures, comminuted fractures and irreducible metacarpal spiral shaft fracture by closed manipulation. At final follow up all the cases were assessed with total active motion(TAM), rotational deformity, bony union and angular deformity based on the plain radiographes. RESULTS: At the last follow-up, all cases achieved bony union. Five cases showed less than 5degrees of dorsal angular deformity. The average union period was 6.3 weeks (range, 5-9weeks). Fifteen cases (79%) showed excellent results, four cases good results based on TAM. No case showed rotational deformity. Two cases had skin irritation by distal wire end, which was subsided after wire removal. CONCLUSIONS: In patients with a metacarpal shaft fracture, retrograde intramedullary fixation using two pre-bent K-wires can provide satisfactory clinical results.
Bone Wires
;
Congenital Abnormalities
;
Follow-Up Studies
;
Fractures, Comminuted
;
Humans
;
Skin
;
Thumb
10.Clinical Analysis of Chemonucleolysis for Treatment of Lumbar Disc Herniation.
Jowa Hyuk IHM ; Seung Chan BAEK ; Sam Kyu KO ; Yong Chul CHI ; Byung Yeran CHOI ; Choong Bae MOON ; Soo Ho CHO
Yeungnam University Journal of Medicine 1986;3(1):171-177
During last 48 months, in our department 5 patients with single or multiple herniated lumbar discs have received chemonucleolysis. Forty-one of r51 cases have single level herniation and remaining cases have multiple level. Age distribution were from 19 to 59 years old. Over 4 months (longest case: 18 months) follow up revealed as follows: 40 cases (78%) revealed excellent results: 4 cases (7.8%) received discectomy 3-6 months after chemonucleolysis because of recurred symptoms: no anaphylaxis and no major complications were noted.
Age Distribution
;
Anaphylaxis
;
Diskectomy
;
Follow-Up Studies
;
Humans
;
Intervertebral Disc Chemolysis*