No abstract available.
Ferritins* ; Humans

No abstract available.
Child* ; Heart Diseases* ; Heart* ; Humans ; Incidence* ; Tricuspid Valve Insufficiency*

No abstract available.
Achilles Tendon* ; Xanthomatosis*

No abstract available.

Regional left ventricular dysfunction is common in patients with coronary artery disease and accurate analysis of regional dysfunction is of particular interest. For the quantitative assessment of regional dysfunction, we measured regional ejection fraction by radial sector division method in 19 patients with acute myocardial infarction and 13 normal controls who had multigated blood pool scan. And two independent observer analyzed regional wall motion using 5 point grading system in 18 patients undergoing radionuclide ventricular cineangiography. The results obtained were as follows : 1) Regional wall motion scores for the gated blood pool study agreed completely in 72 of 108 segments (66.7%) and agreed within 1 grade in 88 of 108 segments(81.5%) and agreement rate is lowest in the septal area. 2) Global left ventricular ejection fraction was 63.2+/-4.2% in normal controls, 36.6+/-6.8% in extensive anterior wall infarction group and 52.6+/-9.7% in inferior wall infarction group. The value of extensive anterior wall infarction group was significantly lower than that of inferior wall infarction group(p<0.005). 3) Regional left ventricular ejection fraction by radial sector division method in normal control group were as follows : area 1 ; 56.5+/-6.7%, area 2 : 77.9+/-4.8%, area 3 ;84.3+/-5.5%, area 4 : 76.8+/-6.6%, area 5 ; 84.7+/-7.6%, area 6 ; 85.9+/-11.2%, area 7 ; 75.5+/-12.3%, area 8 ; 74.9+/-14.0%, area 9 ; 75.5+/-8.8%, area 10 ; 54.2+/-11.0%, 11 ; 34.5+/-16.3, area 12 ; 37.1+/-18.0%. 4) Mean regional ejection fraction in 7 patients with anterior wall infarction showed significantly lower values in area 4 to area 8, and in area 2 to area 5 in case of inferior wall infarction group. 5) We thought that regional ejection fraction obtained by radial sector division method is valuable index for the management and evaluation of patients with coronary artery disease.
Cineangiography ; Coronary Artery Disease ; Humans ; Infarction ; Myocardial Infarction* ; Septum of Brain ; Stroke Volume ; Ventricular Dysfunction, Left

To create an experimental glaucoma model in rabbit and to study the effect of elevated intraocular pressure (IOP) on rabbits ocular tissues, we treated trabecular meshwork of 7 adult pigmented rabbits with Q-switched Nd:YAG laser. And then we studied the IOP lowering effect of topical verapamil in experimental glaucoma model. The IOP and outflow facility were measured with an applanation pneumotonograph (Alcon, Texas). During sustained rap elevation, 50ul of 0.25% verapamil was instilled in one eye and normal saline in the fellow eye. The IOP was measured 1, 2, 4, 8 hours after instillation. The measurement was repeated twice at 2 weeks interval. After 5 weeks, the IOP increased from an average baseline IOP of 16.6mmHg to 25.51mmHg, an increase of 55.6%. The outflow facility was decreased from 0.21 microliter/min/mmHg to 0.09 microliter/min/mmHg. There were statistically significant reductions in IOP in both verapamil and placebo-treated eyes(p<0.05). The reduction was greater in verapamil-treated eyes than in placebo-treated eyes(p<0.05). Maximal reduction of IOP was observed 2 hours after single-drop of verapamil, with significant reduction of IOP up to 4 hours duration(p<0.05). During the observation period of this study, cupping of the optic nerve head developed. Histopathologic examination revealed extensive scarring of the anterior chamber angle structure. There are marked hyaline degeneration of retinal ganglion cells in temporal retina.
Adult ; Anterior Chamber ; Cicatrix ; Glaucoma* ; Humans ; Hyalin ; Intraocular Pressure ; Optic Disk ; Rabbits* ; Retinal Ganglion Cells ; Trabecular Meshwork ; Verapamil*

No abstract available.
Factor X*

Retinal hemorrhages in the newborn infant were first described shortly after the invention of the ophthalmoscope(Jaeger. 1961). Frequency of the retinal hemorrhages in the newborn infant has been reported to be between 2.6 and 50%. We postulate that the retinal hemorrhages are caused by maternal factors and fetal factors. Maternal factors include delivery type, maternal age, duration of pregnancy, parity, duration of labor, and maternal blood pressure. Fetal factors include color of the amnionic fluid, body weight, and sex. We examined the fundus of 161 newborn infants and investigated the above factors that influenced the retinal hemorrhages. The results were as follows: 1. The overall incidence of the retinal hemorrhages were 35.4%. 2. According to the delivery types, retinal hemorrhages were found in 57.9% after vacuum extraction, in 41.7% after induction delivery, in 33.8% after spontaneous delivery, and in 13.5% after Cesarean section. 3. As the duration of pregnancy increased in complicated delivery, retinal hemorrhages also tendted to increase. 4. The incidence of hemorrhages were greater in the hypertensive mother and abnormal color of amnionic fluid in spontaneous delivery. 5. The incidence of retinal hemorrhages were greater in the high body weight, multipara, and normal duration of labor. 6. Retinal hemorrhages were not related the maternal age and fetal sex. 7. Retinal hemorrhages were absorbed within four weeks.
Amnion ; Blood Pressure ; Body Fluids ; Body Weight ; Cesarean Section ; Female ; Hemorrhage ; Humans ; Incidence ; Infant, Newborn ; Inventions ; Maternal Age ; Mothers ; Parity ; Pregnancy ; Retinal Hemorrhage* ; Retinaldehyde* ; Vacuum

A statistical study was done on arrhythmia of the aged who were older than 60 during the period 1963~1972 at Seoul national University Hospital. This study included 6,511 patients among 40,000 total patients. The results were as follows. 1) Arrhythmias were observed among 3,058 patients(46.97%). Sinus irregularitis were the most frequent arrhythmia. 2) Except sinus irregularities premature beat (38.3%), atrial fibrillation (16.1%), bundle branch block (10.5%), atriovenricular block (10.5%), atrioventricular escape beat (5.1%), atrioventricular junctional rhythm (4.9%), wandering pacemaker(4.0%) and paroxysmal tachycardia(2.5%) were frequent arrhythmias. 3) Cardiovascular disease was major underlying disease. In cardiovascular disease group, the incidence of arrhythmia was 51.15% which was three times as high as non-cardiovascular and normal group. 4) Most arrhythmias were more frequently observed among the aged except bundle branch block and ventricular paroxysmal tachycardia. 5) The incidence of arrhythmia was similar among the aged except pre-excitation syndrome which was predisposed to woman. 6) Arrhythmia was most frequently observed in coronary heart disease. 7) Among sinus irregularities, simus bradycardia was more frequent in the aged. 8) There were no significant differences in frequency of arrhythmia between non-cardiovascular disease group patients and normal group.
Arrhythmias, Cardiac* ; Atrial Fibrillation ; Bradycardia ; Bundle-Branch Block ; Cardiac Complexes, Premature ; Cardiovascular Diseases ; Coronary Disease ; Female ; Humans ; Incidence ; Pre-Excitation Syndromes ; Seoul ; Statistics as Topic* ; Tachycardia, Paroxysmal ; United Nations

Nerve fiber bundle index(NFBI) is a new index which detects visual field depression in 21 nerve fiber bundle zones, reflecting the topographical arrangement of visual field defects. We applied this index to 39 eyes with normal visual field and 131 eyes with early glau-comatous field defect(mean defect Area Under Curve ; Depression ; Glaucoma* ; Nerve Fibers* ; ROC Curve ; Visual Fields