1.A Case of Cryptococcosis with Advanced Pulmonary Tuberculosis.
Hi Ju PARK ; Yong Joon KIM ; Sang Kun JUNG ; Chan Yung KIM
Journal of the Korean Pediatric Society 1986;29(1):95-100
No abstract available.
Cryptococcosis*
;
Tuberculosis, Pulmonary*
2.A case of polyethemia associated CAPD on a chronic renal failure patient.
Chan Su JEONG ; Jung Woong LEE ; Kyung Kun HAN ; Jong Hyun KIM ; Young Sung JAE
Korean Journal of Nephrology 1992;11(4):482-486
No abstract available.
Humans
;
Kidney Failure, Chronic*
;
Peritoneal Dialysis, Continuous Ambulatory*
3.A Case of Relapsing Polychondritis.
Yong Joon KIM ; Hee Joo JEON ; Bong Joon CHUNG ; Hi Ju PARK ; Sang Kun JUNG ; Chan Yung KIM
Journal of the Korean Pediatric Society 1986;29(12):76-81
No abstract available.
Polychondritis, Relapsing*
4.A Case of Relapsing Polychondritis.
Yong Joon KIM ; Hee Joo JEON ; Bong Joon CHUNG ; Hi Ju PARK ; Sang Kun JUNG ; Chan Yung KIM
Journal of the Korean Pediatric Society 1986;29(12):76-81
No abstract available.
Polychondritis, Relapsing*
5.A Case of Lymphangioma of the Large Intestine Removed by Colonoscopic Polypectomy.
Kun Hoon SONG ; Hyo Min YOO ; Won Ho KIM ; Ki Ho PARK ; Jin Kyung KANG ; In Suh PARK ; Yoon Jung CHOI ; Chan Il PARK
Korean Journal of Gastrointestinal Endoscopy 1993;13(2):401-404
Lymphangioma occuring in the gastrointestinal tract is a rare benign tumor, which is composed of lymphatic vessels of various size. A sharply demarcated smooth, soft, cystic submucosal tumor which is easily compressible and covered with normal mucosa is a characteristic eadoscapic feature. Recently, we experienced a case of lymphangioma in ascendmg colon and removed it successfully by colonoscopic snare polypectomy.
Colon
;
Colonoscopy
;
Gastrointestinal Tract
;
Intestine, Large*
;
Lymphangioma*
;
Lymphatic Vessels
;
Mucous Membrane
;
SNARE Proteins
6.Tissue Plasminogen Activator in the Treatment of Fibrinous Membrane after Cataract Surgery.
Jung Il MOON ; Sung Kun CHUNG ; Yoon Won MYONG ; Sang Moon CHUNG ; Chan PARK ; Nam Ho BAEK ; Sang Wook RHEE
Journal of the Korean Ophthalmological Society 1991;32(5):328-333
We injected tPA into the anterior chamber of 43 pesudophakic eyes with moderate to severe fibrinous membrane which had developed following cataract surgery from January, 1990 to August, 1990 at St. Mary's hospital. The results were as follows: 1. Intraocular tPA injection was resulted in complete fibrinolysis within 1 hour in 38 of 43 eyes and patial fibrinolysis in 5 of 43. 2. No corneal endothelial cell loss was found, and tPA did not appear to cause a significant rise in intraocular pressure. 3. Complications of tPA injection included mild, transient, periocular pain(3 eyes), anterior chamber fibrin debris(2 eyes) and anterior chamber hemorrhage(1 eye). The results indicated that tPA is dramatically effective for the clearance of fibrinous membrane after cataract surgery.
Anterior Chamber
;
Cataract*
;
Corneal Endothelial Cell Loss
;
Fibrin*
;
Fibrinolysis
;
Intraocular Pressure
;
Membranes*
;
Tissue Plasminogen Activator*
7.Prolonged Ischemic Cerebral Infarct in the Rat after Middle Cerebral Artery Occlusion: Part 1:Evolution and Time Course of the Infarction.
Chun Kun PARK ; Chul Ku JUNG ; Dal Soo KIM ; Moon Chan KIM ; Joon Ki KANG
Journal of Korean Neurosurgical Society 1989;18(4):505-514
Although evolution and time course of ischemic brain infarct should be a matter of interest to investigators in the research of brain ischemia as well as traumatic brain injury, few papers have ever been reported. Authors observed quantitatively sequential changes of infarct size and regional cerebral blood flow(rCBF) to assess the evolution of focal ischemic brain infarct in the rat following left MCAO. Fifteen rats, weighting 250 g to 370 g, were used in this experiment. The experiment animals were divided into three groups: 6, 24 and 48 hours groups(HG) after MCAO. The rCBF of bilateral caudate nuclei was measured by hydrogen clearance methods. Areas of brain infarction were delineated by tripheny-tetrazolium chloride(TTC) at the preselected 8 coronal levels of forebrain. The areas of brain damage were drawn on scale diagrams(x4 actual size) of forebrain and measured by a plannimeter. In the experimental groups, just after MCAO, rCBF of the ipsilateral caudate nucleus was reduced to 29.4+/-6.5 to 24.5+/-7.9 ml/100 g/min from the basal value of around 117 to 121 ml/100 g/min and showed a tendency of getting more reduced to 19.4+/-7.6 ml/100 g/min by 48 hours. The rCBF of the contralateral caudate nucleus was maintained in the basal value throughout the experiment. Comparing the total amounts of ischemic damage of 48 HG to those of 5 and 24 HG, the infarction size was significantly increased in cerebral hemisphere as well as cerebral cortex and caudate nucleus(p<0.05). But there was not any significant difference between 6 and 24 HG. The experiment provides evidence for the evolution of focal ischemic brain infarct without any further change of decreased rCBF. The data suggest that it is desirable to observe the change of pathologic findings by not less then 48 hours following the arterial occlusion in the study of ischemic brain infarction in the rat, particularly as long as ischemic damage is delineated by TTC.
Animals
;
Brain
;
Brain Infarction
;
Brain Injuries
;
Brain Ischemia
;
Caudate Nucleus
;
Cerebral Cortex
;
Cerebrum
;
Humans
;
Hydrogen
;
Infarction*
;
Infarction, Middle Cerebral Artery*
;
Middle Cerebral Artery*
;
Prosencephalon
;
Rats*
;
Research Personnel
8.Serum Leptin Levels in Patients with Thyroid Dysfunction.
Min hO SONG ; Young Kun KIM ; Heung Kyu RO ; Hee Jung HAN ; Won Chan JOO ; Jin Ho WON ; Yoon KIM ; Hyun Jin KIM ; Soo Heung CHAE
Journal of Korean Society of Endocrinology 1999;14(2):372-378
BACKGROUND: Leptin, the product of ob gene, is an important circulating hormone for the regulation of homeostasis of body weight and enegy expenditure. There was a previous reports that thyroid hormone is one of regulating factors of leptin gene expression in vitro. The aim of this study was designed to evaluate the role of thyroid hormone levels in the regulation of circulating leptin concentrations in human. METHODS: A total 16S subjects were studied; 76 patients with Graves disease, 49 patients with Hashimoto disease and 43 control sujjects. The correlation between thryoid hormone and leptin levels were analyzed and serum leptin levels were compared among the groups which was classified by thyroid functional status. Serum leptin concentratios were measured by radioimmunoassay. RESULTS: There were no significant differences in serum leptin levels between the groups of control, Graves disease and Hashimoto disease. The hypothyroid groups of Graves disease which was induced by excessive antithyroid drug treatment showed significant low levels(5.6 +/-2.8 ng/mL) compared to control(9.6 +/- 5.2 ng/ml) and thyrotoxic groups(10.0 +/- 5,0 ng/mL) CONCLUSION: The hypothyroid patients showed low levels of serum leptin concentrations it may indicate that thyroid horrnone play a role in the appropriate secretion of leptin in human.
Body Weight
;
Gene Expression
;
Graves Disease
;
Hashimoto Disease
;
Health Expenditures
;
Homeostasis
;
Humans
;
Leptin*
;
Radioimmunoassay
;
Thyroid Gland*
9.A Clinical Analysis of Hypertensive Intracerebral Hematoma.
Kye Hee YOO ; Young Il KIM ; Jung Kun SUH ; Hoon Kap LEE ; Ki Chan LEEM ; Jeong Wha CHU
Journal of Korean Neurosurgical Society 1987;16(1):87-102
Hypertensive intracerebral hematoma is a serious and potentially lethal condition. The indication of surgery in this hematoma is still controversial. Authors have treated 335 cases of hypertensive intracerebral hematomas which were confirmed by computerized tomography between July 1, 1982 and June 30, 1986. The hematomas have been classified according to their modes of extension on computerized tomography. The outcome was assessed on their basis of activity daily living. According to our study, moderate and severe types of putaminal hematoma cases have shown better results with surgery than conservative management. Mortality was 23.7 percent in surgery and 35.3 percent in conservative management.
Hematoma*
;
Mortality
;
Putaminal Hemorrhage
10.Cerebroelectrophysiological Studies on the Cerebrocerebellar Projections in the Increased Intracranial Pressure.
Sang Won LEE ; Joon Ki KANG ; Moon Chan KIM ; Chun Kun PARK ; Chul Ku JUNG ; Young KIM ; Jin Un SONG
Journal of Korean Neurosurgical Society 1987;16(1):139-156
We investigated the electrophysiological changes in the cerebral cortical evoked potentials(CEP's) and subsequent changes in the regional cerebral blood flow(rCBF) following increased intracranial pressure(ICP) in cats. A small balloon connected to a fine polyethylene tube was placed on the epidural space of the left parietal region through a small burr hole and inflated with saline in increment of 0.2 ml to simulate the expanding mass. The ICP was maintained at 150 mmH2O and 250 mmH2O levels during the experimental period. The study was conducted with 30 adult cats, weighing between 2.7 and 4.5kg. The animals were anesthetized with pentobarbital (50mg/kg) intraperitonially and tracheostomy was performed to maintain self respiration. Two small burr holes were made on both frontal regions for rCBF measurement and a small burr hole was made on the right primary sensorimotor cortex for a cerebral cortical stimulating electrode. A recording electrode for CEP's was placed on the dura of the left cerebellar hemisphere. For experiments, animals were divided into 3 groups. Group I:Animals(n=10) with 80mmH2O of ICP, Group II:Animals(n=10) with 150 mmH2O of ICP, Group III:Animals(n=10) with 250mmH2O of ICP. The CEP's and rCBF measurements were carried out in each animal before and immediately after increased ICP(IICP), at the 30th min, 60th min, 90th min, 120th min, 150th min and 180th min after IICP. The rCBF was measured by hydrogen clearance method. The results were as follows ; 1. A significant elevation of the systolic blood pressure was observed after the 60th min in both IICP groups. 2. 1) Group II animals showed a significant reduction of rCBF by 10.5% and 39.5% in the right frontal lobe at the 60th min and 180th min after IICP, and by 19.8% and 57.7% in the left frontal lobe at the 60th min and 180th min after IICP, respectively. 2) Group III animals showed also a significant reduction of rCBF by 18.2% and 54.4% in the right frontal lobe at the 60th min and 180th min after IICP, and by 62.9% and 84.7% in the left frontal lobe at the 60th min and 180th min after IICP, respectively. 3) Reductions of the rCBF of the left frontal lobe in the Group III animals were greater than those of the Group II animals. 3. 1) Changes of amplitude and latency in the CEP's were more prominent in the Group III animals than those of the Group II animals. 2) Changes of the late components of CEP's(N2) might represent derangements of the neural activity of the descending reticular formation in brainstem. 4. A close correlation was found between CEP's and rCBF changes, which suggested being a threshold relationship. In conclusion, it is assumed that the detection of CEP's in the cerebellum is a quite valuable prognostic tool to evaluate the neural activity of the non-specific reticular formation and specific somatosensory pathways in the acute intracranial hypertension. The prolongated latencies and suppressed amplitude in the CEP's indicate the presence of damages in brainstem multisynaptic pathways.
Adult
;
Animals
;
Blood Pressure
;
Brain Stem
;
Cats
;
Cerebellum
;
Electrodes
;
Epidural Space
;
Frontal Lobe
;
Humans
;
Hydrogen
;
Intracranial Hypertension
;
Intracranial Pressure*
;
Pentobarbital
;
Polyethylene
;
Rabeprazole
;
Respiration
;
Reticular Formation
;
Tracheostomy