1.Analysis of Aqueous Humor Calcium and Phosphate from Cataract Eyes with and without Diabetes Mellitus.
Chan Joong KIM ; Sang Kyung CHOI
Korean Journal of Ophthalmology 2007;21(2):90-94
PURPOSE: To compare the levels of calcium and phosphorus in the aqueous humor and serum of diabetics and non-diabetics. METHODS: We divided patients into two groups: seventy-six non-diabetic cataract patients and fifty-two diabetic cataract patients. The diabetic group was divided again into three subgroups: twenty-six patients with no diabetic retinopathy, thirteen patients with non-proliferative diabetic retinopathy, and thirteen patients with proliferative diabetic retinopathy. The authors compared the levels of calcium and phosphorus in the serum and aqueous humor of cataract patients. Statistic analysis was performed to form two comparisons: 1) a comparison between non-diabetics and diabetics and 2) a comparison among non-diabetics and the three subgroups of diabetics. RESULTS: In serum, calcium levels did not statistically differ between non-diabetics and diabetics. The phosphorus level was also not significantly different. In the aqueous humor, however, while calcium levels did not differ significantly, the phosphorus levels in diabetics were considerably higher than those in non-diabetics. When non-diabetics were compared to the three diabetic subgroups, calcium levels did not differ in serum or aqueous humor, but the phosphorus levels in diabetics with proliferative diabetic retinopathy were significantly higher than those in non-diabetics, diabetics without diabetic retinopathy, and diabetics with non-proliferative diabetic retinopathy. CONCLUSIONS: The level of phosphorus in the aqueous humor and serum of diabetics was significantly increased, especially in diabetics with proliferative diabetic retinopathy. This result may be related to hydrophilic acrylic IOL opacification. Future studies regarding the pathogenic role of a high concentration of aqueous humor and serum phosphorus are required.
Aged
;
Aged, 80 and over
;
Aqueous Humor/*chemistry
;
Biological Markers/analysis
;
Calcium/*analysis
;
Cataract/complications/*metabolism
;
Diabetic Retinopathy/complications/*metabolism
;
Female
;
Humans
;
Male
;
Middle Aged
;
Phosphorus/*analysis
;
Regression Analysis
;
Retrospective Studies
2.Analysis of Aqueous Humor Calcium and Phosphate from Cataract Eyes with and without Diabetes Mellitus.
Chan Joong KIM ; Sang Kyung CHOI
Korean Journal of Ophthalmology 2007;21(2):90-94
PURPOSE: To compare the levels of calcium and phosphorus in the aqueous humor and serum of diabetics and non-diabetics. METHODS: We divided patients into two groups: seventy-six non-diabetic cataract patients and fifty-two diabetic cataract patients. The diabetic group was divided again into three subgroups: twenty-six patients with no diabetic retinopathy, thirteen patients with non-proliferative diabetic retinopathy, and thirteen patients with proliferative diabetic retinopathy. The authors compared the levels of calcium and phosphorus in the serum and aqueous humor of cataract patients. Statistic analysis was performed to form two comparisons: 1) a comparison between non-diabetics and diabetics and 2) a comparison among non-diabetics and the three subgroups of diabetics. RESULTS: In serum, calcium levels did not statistically differ between non-diabetics and diabetics. The phosphorus level was also not significantly different. In the aqueous humor, however, while calcium levels did not differ significantly, the phosphorus levels in diabetics were considerably higher than those in non-diabetics. When non-diabetics were compared to the three diabetic subgroups, calcium levels did not differ in serum or aqueous humor, but the phosphorus levels in diabetics with proliferative diabetic retinopathy were significantly higher than those in non-diabetics, diabetics without diabetic retinopathy, and diabetics with non-proliferative diabetic retinopathy. CONCLUSIONS: The level of phosphorus in the aqueous humor and serum of diabetics was significantly increased, especially in diabetics with proliferative diabetic retinopathy. This result may be related to hydrophilic acrylic IOL opacification. Future studies regarding the pathogenic role of a high concentration of aqueous humor and serum phosphorus are required.
Aged
;
Aged, 80 and over
;
Aqueous Humor/*chemistry
;
Biological Markers/analysis
;
Calcium/*analysis
;
Cataract/complications/*metabolism
;
Diabetic Retinopathy/complications/*metabolism
;
Female
;
Humans
;
Male
;
Middle Aged
;
Phosphorus/*analysis
;
Regression Analysis
;
Retrospective Studies
3.Corneal Endothelial Cell Change with Different Phacoemulsification Time in Diabetic Patients.
Chan Joong KIM ; Sang Kyung CHOI
Journal of the Korean Ophthalmological Society 2007;48(11):1473-1478
PURPOSE: To investigate the difference in corneal endothelial cell loss between diabetic and non-diabetic patients who were divided by the degree of phacoemulsification time after phacoemulsification with intraocular lens implantation. METHODS: Forty eyes of 30 patients with diabetes and 47 eyes of 36 patients without diabetes were divided by phacoemulsification time into 3 groups: less than 40 seconds, from 40 to 80 seconds and over 80 seconds. The corneal endothelial cell density was compared before and 1, 4 and 16 weeks after phacoemulsification by one-way ANOVA. Bivariate correlation analysis was used to identify the correlation between phacoemulsification time and the endothelial density before and 1, 4 and 16 weeks after phcoemulsification. RESULTS: The endothelial cell densities in diabetic and non-diabetic patients with different phacoemulsification time were not significantly different when compared before and 1, 4 and 16 weeks after phacoemulsification (P>0.05). Phacoemulsificaiton time and endothelial cell loss at 1, 4 and 16 weeks also showed no significant correlation. CONCLUSIONS: Diabetes and differences in phacoemulsification time had no significant influence on corneal endothelial cell loss. This result suggests uncomplicated phacoemulsificaion is a safe method for cataract extraction in patients with or without diabetes.
Cataract
;
Cataract Extraction
;
Cornea
;
Corneal Endothelial Cell Loss
;
Endothelial Cells*
;
Endothelium
;
Humans
;
Lens Implantation, Intraocular
;
Phacoemulsification*
4.The Effect of Lithotomy Position on Hyperbaric Tetracaine Spinal Anesthesia.
Joong Ho KIM ; Chan KIM ; Whun Kon PARK ; Ryoung CHOI
Korean Journal of Anesthesiology 1990;23(2):243-246
The effect of hyperbaric tetracaine spinal anesthesia was studied in 40 patients having genitourinary surgery in the horizontal lithotomy position. Patients were randomly assigned to one of two groups, after spinal injection, patients in one group were placed immediately in the supine and horizontal lithotomy position, and patients in the second group were placed immediatley in the supine and horizontal position for 10 minutes and then placed into the horizontal 1thotomy position. There were no statistically significant differences in anesthesia sensory level and heart rate of patients placed immediately in the horizontal lithotomy position compared to the patients kept in the supine position for the first 10 minutes after receiving the spinal anesthetic. The ranges of systolic blood pressure were all within normal limits, although systolic blood pressure showed a difference at 5,10 and 60 minute intervals after anesthesia. We conclude that immediate application of the horizontal lithotomy position can be safely practiced in the anesthesia of genitourinary surgery.
Anesthesia
;
Anesthesia, Spinal*
;
Blood Pressure
;
Heart Rate
;
Humans
;
Injections, Spinal
;
Supine Position
;
Tetracaine*
5.A Case of Papillary Tubular Adenoma (Tubulopapillary Hidradenoma).
Kyoung Ae JANG ; Il Joong PARK ; Jee Ho CHOI ; Kyung Jeh SUNG ; Kee Chan MOON ; Jai Kyoung KOH
Annals of Dermatology 1999;11(3):197-201
Tubular apocrine adenoma and papillary eccrine adenoma are rare sweat gland neoplasms that appear as a small solitary lesion on the scalp or extremities, respectively. Although these lesions are thought to be distinct entities, there are enough similarities between them to group them under the term tubulopapillary hidradenoma or papillary tubular adenoma. We describe a case showing many tubular structures with papillary projection, syringocystadenoma-like structures, and eccrine hirocystoma-like structures in the axillary area. The term of papillary tubular adenoma or tubulopapillary hidradenoma may be prefered in this case.
Acrospiroma
;
Adenoma*
;
Extremities
;
Scalp
;
Sweat Gland Neoplasms
6.One Case of Pulmonary Thromboembolism Suspected during Cesarean Section.
Won Joong KIM ; Seung Ju SHIN ; Woo Seob JANG ; Byoung Sung KIM ; Kwang Hyun KIM ; Mi Young CHOI ; Chan PARK
Korean Journal of Perinatology 2001;12(3):348-352
No abstract available.
Cesarean Section*
;
Female
;
Pregnancy
;
Pulmonary Embolism*
7.Association of Metabolic Factors and Prostate-Specific Antigen Levels with Prostate Volume in Medical Check-ups.
Eun Hee NAH ; Han Ik CHO ; Joong Chan CHOI
Laboratory Medicine Online 2014;4(4):212-217
BACKGROUND: Baseline prostate volume (PV) is related with the progression of benign prostatic hyperplasia (BPH). Although recent studies have reported the relationship between BPH and metabolic syndrome, the findings are inconsistent. Thus, this study was performed to investigate the association of PV with metabolic factors and prostate-specific antigen (PSA) in individuals with normal PV and clarify the factors associated with benign prostate enlargement (BPE), including PSA. METHODS: We selected 3,915 health examinees aged >40 yr with a PSA level <4 ng/mL who underwent ultrasonography of the prostate as part of a routine health check-up. These individuals were classified into two groups according to PV: normal PV (PV <30 mL) and BPE (PV > or =30 mL). We investigated the association of PV with metabolic factors and PSA using multiple linear regression analysis, and clarified the factors associated with BPE using logistic regression analysis. RESULTS: The factors associated with PV were PSA, age, and waist circumference in individuals with normal PV. The factors associated with BPE were age, body mass index (BMI), and PSA. The logistic regression analysis adjusted for age and confounding factors showed that individuals with a BMI of 23-24.9 kg/m2, 25-29.9 kg/m2, and > or =30 kg/m2 had higher odds ratios of 1.580 (95% confidence interval, 1.171-2.131; P=0.003), 1.767 (1.332-2.344; P<0.001), and 2.024 (1.042-3.933; P=0.038), respectively, for BPE than individual with a BMI <23 kg/m2. CONCLUSIONS: Abdominal obesity was significantly associated with PV in individuals with normal PV, whereas obesity was an associated metabolic factor of BPE. PSA level was positively associated with PV.
Body Mass Index
;
Linear Models
;
Logistic Models
;
Obesity
;
Obesity, Abdominal
;
Odds Ratio
;
Prostate*
;
Prostate-Specific Antigen*
;
Prostatic Hyperplasia
;
Ultrasonography
;
Waist Circumference
8.Comparison of Three Types of Hernioplasty Using Meshes for Adult Inguinal Hernia: Lichtenstein, Mesh-plug, Prolene Hernia System.
Chan Joong CHOI ; Ki Jae PARK ; Sung Heun KIM
Journal of the Korean Surgical Society 2009;76(2):109-114
PURPOSE: The aim of this study was to compare three types of hernioplasty using a mesh: Lichtenstein, Mesh-plug and Prolene Hernia System. METHODS: From February 2002 to April 2007, we retrospectively studied the clinical outcome of 138 cases of adult inguinal hernia patients who had operations performed with the use of mesh. Three types of mesh operations were composed of Lichtenstein repair group (LR group; N=18), Mesh plug repair group (MR group; N=38) and Prolene hernia system group (PHS group; N=82). The Clinical features and outcomes of the three groups were compared by age, sex, operation time, lengths of hospital stay, numbers of post-operative intravenous analgesics, complications, and recurrence. RESULTS: Mean age of three groups was 50.2+/-20.7, 51.0+/-18.4 and 61.5+/-15.9 years for LR. MR, PHS groups, respectively. The PHS group was significantly older than other two groups (P=0.002). The sex, operation time and lengths of hospital stay were not significantly different among the three groups. Numbers of intravenous analgesics used after the operations were 1.7+/-1.2, 2.7+/-2.2, 3.3+/-2.0 in the LR, MR, PHS groups, respectively. A lesser amount of IV analgesics was injected into the LR group than the PHS group. Although some complications occurred such as wound infection, hematoma, dehiscence, testicular edema in the three groups, there were no significant differences among the three groups. There were no recurrences in all three groups. CONCLUSION: We could not find any better outcome among the LR, MR and PHS groups.
Adult
;
Analgesics
;
Edema
;
Hematoma
;
Hernia
;
Hernia, Inguinal
;
Herniorrhaphy
;
Humans
;
Hydrogen-Ion Concentration
;
Length of Stay
;
Polypropylenes
;
Recurrence
;
Retrospective Studies
;
Wound Infection
9.Bilateral Rapid Distraction of Mandible.
Sukwha KIM ; Joong Hyuk CHOI ; Jae Chan KIM ; Chul Gyoo PARK ; Woo Jung KIM
Journal of the Korean Cleft Palate-Craniofacial Association 2003;4(2):95-99
Bilateral mandibular hypoplasia is found in Treacher Collins syndrome, Pierre Robin sequence, and bilateral craniofacial microsomia. It causes many aesthetic and functional problems such as facial deformities with malocclusion and airway problems. We have corrected bilateral hypoplastic mandible with distraction osteogenesis, which is a highlighted method in mandibular lengthening. For last 3 years 8 months, We applied this method to four bilateral cases, where were Treacher Collins syndrome patients and bilateral craniofacial microsomia patient in rapid multidirectional fashion. A complete ostectomy was made at angle of the mandible and the mandible was fixed 5 days after lengthening was started serially 1mm every 12 hours. After consolidation period for one to three month, the device was removed. We have distracted the mandibles in vertical plane, left.18.8mm, right. 13.4mm, in horizontal plane, left 13.9mm, right 13.7mm on the average. We could achieve good aesthetic results, and their airway problems were improved without any complications.
Congenital Abnormalities
;
Goldenhar Syndrome
;
Humans
;
Malocclusion
;
Mandible*
;
Mandibulofacial Dysostosis
;
Osteogenesis, Distraction
;
Pierre Robin Syndrome
10.The Diagnostic Accuracy of Preoperative T- staging of Gastric Cancer Using EUS and CT.
Ki Han KIM ; Min Chan KIM ; Seok Reyol CHOI ; Ghap Joong JUNG ; Hyung Ho KIM
Journal of the Korean Gastric Cancer Association 2003;3(4):182-185
PURPOSE: Preoperative staging of gastric cancer is crucial because the treatment modality and the prognosis depend upon the stage of gastric cancer. Current treatment modalities for early gastric cancer have focused on the quality of life. Endoscopic ultrasonography (EUS) and abdominal computed tomography (CT) are commonly used diagnostic tools to evaluate the invasiveness (T stage) of the primary tumor. The purpose of this paper is to evaluate the sensitivity and the specificity of preoperative EUS and CT in comparison with postoperative pathology. MATENRIALS AND METHODS: From October 2001 to October 2002, EUS and abdominal CT were performed simultaneously on 75 patients who underwent radical gastric surgery for the treatment of gastric cancer. Through analyzing the clinical T stage and the pathologic T stage, We evaluated the diagnostic sensitivities and specificities of endoscopic ultrasonography and abdominal computed tomography. RESULTS: The male-to-female sex ratio was 1:0.6 (males:47, females:28). The mean age was 55.4 years in males (range:28~81) and 54.4 years in females (range:23~77). The clinical T stage based on EUS included 22 T1mm, 7 T1sm, 22 T2, and 24 T3. The clinical T stage based on CT included 20 Tx, 23 T2, and 32 T3. The permanent pathologic report confirmed 23 T1mm, 10 T1sm, 17 T2, 24 T3, and 1 T4. The sensitivity and specificity of EUS were 84.2% and 94.7%, respectively. However, the sensitivity and specificity of abdominal CT were 53.3% and 77.0%, respectively. CONCLUSION: Our data suggest that EUS is a very useful diagnostic tool for evaluating the T stage of gastric cancer because EUS has higher specificity than abdominal CT. Therefore, EUS may have a significant role as a preoperative diagnostic modality in patients undergoing minimally invasive surgery.
Endosonography
;
Female
;
Humans
;
Male
;
Pathology
;
Prognosis
;
Quality of Life
;
Sensitivity and Specificity
;
Sex Ratio
;
Stomach Neoplasms*
;
Surgical Procedures, Minimally Invasive
;
Tomography, X-Ray Computed