Objective: Previous studies have reported an association between cancer-related symptoms and perceived social support (PSS). The objective of this study was to analyze whether Chemotherapy-Induced Peripheral Neuropathy (CIPN), a prevalent side effect of chemotherapy, varies according to PSS level using a validated tool for CIPN at prospective follow-up. Methods: A total of 39 breast cancer patients were evaluated for PSS using the Multidimensional Scale of Perceived Social Support (MSPSS) prior to chemotherapy and were subsequently grouped into one of two categories for each subscale: low-to-moderate PSS and high PSS. CIPN was prospectively evaluated using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Chemotherapy-Induced Peripheral Neuropathy 20 (CIPN20) at five time points. A linear mixed-effects model with square root transformation was employed to investigate whether the CIPN20 scales varied by PSS level and time point. Results: Statistical analysis of the MSPSS total scale and subscales revealed a significant effect of the friends subscale group and time point on the CIPN20 sensory scale. The sensory scale score of CIPN20 was found to be lower in participants with high PSS from friends in comparison to those with low-to-moderate PSS at 1 month post-chemotherapy (p=0.010). Conclusion This is the first study to prospectively follow the long-term effect of pre-treatment PSS from friends on CIPN. Further studies based on larger samples are required to analyze the effects of PSS on the pathophysiology of CIPN.

Objective: Previous studies have reported an association between cancer-related symptoms and perceived social support (PSS). The objective of this study was to analyze whether Chemotherapy-Induced Peripheral Neuropathy (CIPN), a prevalent side effect of chemotherapy, varies according to PSS level using a validated tool for CIPN at prospective follow-up. Methods: A total of 39 breast cancer patients were evaluated for PSS using the Multidimensional Scale of Perceived Social Support (MSPSS) prior to chemotherapy and were subsequently grouped into one of two categories for each subscale: low-to-moderate PSS and high PSS. CIPN was prospectively evaluated using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Chemotherapy-Induced Peripheral Neuropathy 20 (CIPN20) at five time points. A linear mixed-effects model with square root transformation was employed to investigate whether the CIPN20 scales varied by PSS level and time point. Results: Statistical analysis of the MSPSS total scale and subscales revealed a significant effect of the friends subscale group and time point on the CIPN20 sensory scale. The sensory scale score of CIPN20 was found to be lower in participants with high PSS from friends in comparison to those with low-to-moderate PSS at 1 month post-chemotherapy (p=0.010). Conclusion This is the first study to prospectively follow the long-term effect of pre-treatment PSS from friends on CIPN. Further studies based on larger samples are required to analyze the effects of PSS on the pathophysiology of CIPN.

Objective: Previous studies have reported an association between cancer-related symptoms and perceived social support (PSS). The objective of this study was to analyze whether Chemotherapy-Induced Peripheral Neuropathy (CIPN), a prevalent side effect of chemotherapy, varies according to PSS level using a validated tool for CIPN at prospective follow-up. Methods: A total of 39 breast cancer patients were evaluated for PSS using the Multidimensional Scale of Perceived Social Support (MSPSS) prior to chemotherapy and were subsequently grouped into one of two categories for each subscale: low-to-moderate PSS and high PSS. CIPN was prospectively evaluated using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Chemotherapy-Induced Peripheral Neuropathy 20 (CIPN20) at five time points. A linear mixed-effects model with square root transformation was employed to investigate whether the CIPN20 scales varied by PSS level and time point. Results: Statistical analysis of the MSPSS total scale and subscales revealed a significant effect of the friends subscale group and time point on the CIPN20 sensory scale. The sensory scale score of CIPN20 was found to be lower in participants with high PSS from friends in comparison to those with low-to-moderate PSS at 1 month post-chemotherapy (p=0.010). Conclusion This is the first study to prospectively follow the long-term effect of pre-treatment PSS from friends on CIPN. Further studies based on larger samples are required to analyze the effects of PSS on the pathophysiology of CIPN.

Objective: Previous studies have reported an association between cancer-related symptoms and perceived social support (PSS). The objective of this study was to analyze whether Chemotherapy-Induced Peripheral Neuropathy (CIPN), a prevalent side effect of chemotherapy, varies according to PSS level using a validated tool for CIPN at prospective follow-up. Methods: A total of 39 breast cancer patients were evaluated for PSS using the Multidimensional Scale of Perceived Social Support (MSPSS) prior to chemotherapy and were subsequently grouped into one of two categories for each subscale: low-to-moderate PSS and high PSS. CIPN was prospectively evaluated using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Chemotherapy-Induced Peripheral Neuropathy 20 (CIPN20) at five time points. A linear mixed-effects model with square root transformation was employed to investigate whether the CIPN20 scales varied by PSS level and time point. Results: Statistical analysis of the MSPSS total scale and subscales revealed a significant effect of the friends subscale group and time point on the CIPN20 sensory scale. The sensory scale score of CIPN20 was found to be lower in participants with high PSS from friends in comparison to those with low-to-moderate PSS at 1 month post-chemotherapy (p=0.010). Conclusion This is the first study to prospectively follow the long-term effect of pre-treatment PSS from friends on CIPN. Further studies based on larger samples are required to analyze the effects of PSS on the pathophysiology of CIPN.

Objective: Previous studies have reported an association between cancer-related symptoms and perceived social support (PSS). The objective of this study was to analyze whether Chemotherapy-Induced Peripheral Neuropathy (CIPN), a prevalent side effect of chemotherapy, varies according to PSS level using a validated tool for CIPN at prospective follow-up. Methods: A total of 39 breast cancer patients were evaluated for PSS using the Multidimensional Scale of Perceived Social Support (MSPSS) prior to chemotherapy and were subsequently grouped into one of two categories for each subscale: low-to-moderate PSS and high PSS. CIPN was prospectively evaluated using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Chemotherapy-Induced Peripheral Neuropathy 20 (CIPN20) at five time points. A linear mixed-effects model with square root transformation was employed to investigate whether the CIPN20 scales varied by PSS level and time point. Results: Statistical analysis of the MSPSS total scale and subscales revealed a significant effect of the friends subscale group and time point on the CIPN20 sensory scale. The sensory scale score of CIPN20 was found to be lower in participants with high PSS from friends in comparison to those with low-to-moderate PSS at 1 month post-chemotherapy (p=0.010). Conclusion This is the first study to prospectively follow the long-term effect of pre-treatment PSS from friends on CIPN. Further studies based on larger samples are required to analyze the effects of PSS on the pathophysiology of CIPN.

Background: The prevalence of scabies, a contagious parasitic skin disease, has decreased to ＜1% in South Korea.However, an increase in the elderly population has led to occasional outbreaks. This study aimed to analyze the epidemiological changes and clinical features of scabies diagnosed in Ulsan over the past decade. Objective: This study aimed to analyze the epidemiological changes and clinical features of scabies infections diagnosed at a tertiary hospital in Ulsan over the past decade. Methods: We conducted a retrospective study at Ulsan University Hospital that reviewed 235 cases from 2013 to 2022.We analyzed the medical records of patients diagnosed with scabies by dermoscopy and microscopic examination. Results: Among 55,430 patients, 235 were confirmed to have scabies, with an overall prevalence of 0.42%. The highest annual incidence was in 2018 (35 cases), with a subsequent decrease but a gradual increase from 2019 to 2022. The most common infection route was through nursing facilities (32.3%). The elderly (≥70 years) comprised 32.3% cases, and typical clinical manifestations were papules (80.4%) of the trunk and extremities. Eosinophilia was observed in 31.4% inpatients. The mean treatment duration was 29.15 days. Conclusion We report a declining but significant prevalence of scabies in Ulsan, with many cases occurring among the elderly in nursing facilities. This study underscores the need for continued surveillance and education regarding the diagnosis and management of scabies in healthcare and community facilities.

Background: The prevalence of scabies, a contagious parasitic skin disease, has decreased to ＜1% in South Korea.However, an increase in the elderly population has led to occasional outbreaks. This study aimed to analyze the epidemiological changes and clinical features of scabies diagnosed in Ulsan over the past decade. Objective: This study aimed to analyze the epidemiological changes and clinical features of scabies infections diagnosed at a tertiary hospital in Ulsan over the past decade. Methods: We conducted a retrospective study at Ulsan University Hospital that reviewed 235 cases from 2013 to 2022.We analyzed the medical records of patients diagnosed with scabies by dermoscopy and microscopic examination. Results: Among 55,430 patients, 235 were confirmed to have scabies, with an overall prevalence of 0.42%. The highest annual incidence was in 2018 (35 cases), with a subsequent decrease but a gradual increase from 2019 to 2022. The most common infection route was through nursing facilities (32.3%). The elderly (≥70 years) comprised 32.3% cases, and typical clinical manifestations were papules (80.4%) of the trunk and extremities. Eosinophilia was observed in 31.4% inpatients. The mean treatment duration was 29.15 days. Conclusion We report a declining but significant prevalence of scabies in Ulsan, with many cases occurring among the elderly in nursing facilities. This study underscores the need for continued surveillance and education regarding the diagnosis and management of scabies in healthcare and community facilities.

Background: The prevalence of scabies, a contagious parasitic skin disease, has decreased to ＜1% in South Korea.However, an increase in the elderly population has led to occasional outbreaks. This study aimed to analyze the epidemiological changes and clinical features of scabies diagnosed in Ulsan over the past decade. Objective: This study aimed to analyze the epidemiological changes and clinical features of scabies infections diagnosed at a tertiary hospital in Ulsan over the past decade. Methods: We conducted a retrospective study at Ulsan University Hospital that reviewed 235 cases from 2013 to 2022.We analyzed the medical records of patients diagnosed with scabies by dermoscopy and microscopic examination. Results: Among 55,430 patients, 235 were confirmed to have scabies, with an overall prevalence of 0.42%. The highest annual incidence was in 2018 (35 cases), with a subsequent decrease but a gradual increase from 2019 to 2022. The most common infection route was through nursing facilities (32.3%). The elderly (≥70 years) comprised 32.3% cases, and typical clinical manifestations were papules (80.4%) of the trunk and extremities. Eosinophilia was observed in 31.4% inpatients. The mean treatment duration was 29.15 days. Conclusion We report a declining but significant prevalence of scabies in Ulsan, with many cases occurring among the elderly in nursing facilities. This study underscores the need for continued surveillance and education regarding the diagnosis and management of scabies in healthcare and community facilities.

Background: The prevalence of scabies, a contagious parasitic skin disease, has decreased to ＜1% in South Korea.However, an increase in the elderly population has led to occasional outbreaks. This study aimed to analyze the epidemiological changes and clinical features of scabies diagnosed in Ulsan over the past decade. Objective: This study aimed to analyze the epidemiological changes and clinical features of scabies infections diagnosed at a tertiary hospital in Ulsan over the past decade. Methods: We conducted a retrospective study at Ulsan University Hospital that reviewed 235 cases from 2013 to 2022.We analyzed the medical records of patients diagnosed with scabies by dermoscopy and microscopic examination. Results: Among 55,430 patients, 235 were confirmed to have scabies, with an overall prevalence of 0.42%. The highest annual incidence was in 2018 (35 cases), with a subsequent decrease but a gradual increase from 2019 to 2022. The most common infection route was through nursing facilities (32.3%). The elderly (≥70 years) comprised 32.3% cases, and typical clinical manifestations were papules (80.4%) of the trunk and extremities. Eosinophilia was observed in 31.4% inpatients. The mean treatment duration was 29.15 days. Conclusion We report a declining but significant prevalence of scabies in Ulsan, with many cases occurring among the elderly in nursing facilities. This study underscores the need for continued surveillance and education regarding the diagnosis and management of scabies in healthcare and community facilities.

Background: and Purpose Recent studies suggested an increased incidence of cerebral venous thrombosis (CVT) during the coronavirus disease 2019 (COVID-19) pandemic. We evaluated the volume of CVT hospitalization and in-hospital mortality during the 1st year of the COVID-19 pandemic compared to the preceding year. Methods: We conducted a cross-sectional retrospective study of 171 stroke centers from 49 countries. We recorded COVID-19 admission volumes, CVT hospitalization, and CVT in-hospital mortality from January 1, 2019, to May 31, 2021. CVT diagnoses were identified by International Classification of Disease-10 (ICD-10) codes or stroke databases. We additionally sought to compare the same metrics in the first 5 months of 2021 compared to the corresponding months in 2019 and 2020 (ClinicalTrials.gov Identifier: NCT04934020). Results: There were 2,313 CVT admissions across the 1-year pre-pandemic (2019) and pandemic year (2020); no differences in CVT volume or CVT mortality were observed. During the first 5 months of 2021, there was an increase in CVT volumes compared to 2019 (27.5%; 95% confidence interval [CI], 24.2 to 32.0; P<0.0001) and 2020 (41.4%; 95% CI, 37.0 to 46.0; P<0.0001). A COVID-19 diagnosis was present in 7.6% (132/1,738) of CVT hospitalizations. CVT was present in 0.04% (103/292,080) of COVID-19 hospitalizations. During the first pandemic year, CVT mortality was higher in patients who were COVID positive compared to COVID negative patients (8/53 [15.0%] vs. 41/910 [4.5%], P=0.004). There was an increase in CVT mortality during the first 5 months of pandemic years 2020 and 2021 compared to the first 5 months of the pre-pandemic year 2019 (2019 vs. 2020: 2.26% vs. 4.74%, P=0.05; 2019 vs. 2021: 2.26% vs. 4.99%, P=0.03). In the first 5 months of 2021, there were 26 cases of vaccine-induced immune thrombotic thrombocytopenia (VITT), resulting in six deaths. Conclusions During the 1st year of the COVID-19 pandemic, CVT hospitalization volume and CVT in-hospital mortality did not change compared to the prior year. COVID-19 diagnosis was associated with higher CVT in-hospital mortality. During the first 5 months of 2021, there was an increase in CVT hospitalization volume and increase in CVT-related mortality, partially attributable to VITT.