1.Primary Pyogenic Psoas Abscess in Child
Chin Hong KO ; Su Chan LEE ; Sang Gyu KIM
The Journal of the Korean Orthopaedic Association 1995;30(4):1092-1098
Primary pyogenic psoas abscess is rare lesion, and often is not suspected. Reasons for delayed diagnosis are unfamility with the lesion and the fact that symptoms often resemble those of primary disease of the hip. We present a case of primary pyogenic psoas abscess in child, which was diagnosed by MRI, and completely recovered after surgical treatment.
Child
;
Delayed Diagnosis
;
Hip
;
Humans
;
Magnetic Resonance Imaging
;
Psoas Abscess
2.Effects of dexamethasone on salivary function following irradiation.
Hoon Sang CHANG ; Won Pyo HONG ; Gyu Jong CHO ; Young Chan KIM ; Ho Ki LEE
Korean Journal of Otolaryngology - Head and Neck Surgery 1991;34(5):968-977
No abstract available.
Dexamethasone*
3.A Case of Cughing's Disease which Responded to the Combined Treatment of Ketoconazole and Octreotide.
Chan Soo SHIN ; Chang Hoon YIM ; Jae Jun KOH ; Sung Yeon KIM ; Bo Yeon CHO ; Hong Gyu LEE
Journal of Korean Society of Endocrinology 1998;13(1):94-98
The treatment of choice for Cushing's disease is surgical removal of tumor, the source of ACTH overproduction. In occasional patients in whom a surgical approach including total adrenalectomy is not feasible or surgical removal of tumor is not complete, medical treatment may be necessary because pituitary irradiation requires a long 1ag time to remission. Although ketoconazole, an imidazole derivative with inhibitory activity on adrenal steroidogenesis has been reported to be effective in the treatment of Cushing's disease, the limited effectiveness in lowering very high level of cortisol and occasional hepatotoxicity restrains its wide use. In this report, we describe a woman with Cushing's disease due to pituitary microadenoma. Transsphenoidal pituitary adenomeetomy followed by ketoconzole treatment had been unsuccessful in achieving remission of the disease, but combined treatment with ketoconazole and octreotide accomplished successful reduction in cortisol production.
Adrenalectomy
;
Adrenocorticotropic Hormone
;
Female
;
Humans
;
Hydrocortisone
;
Ketoconazole*
;
Octreotide*
;
Pituitary Irradiation
4.Family Function and Children of Alcoholics Screening Test Score in High School Students .
In Wook JUNG ; Jong Sung KIM ; Jin Gyu JUNG ; Keun Bae KIM ; Chan Il PARK ; Won Ki HONG ; Sung Soo KIM
Journal of the Korean Academy of Family Medicine 2007;28(6):436-441
BACKGROUND: Parent's alcohol drinking not only influences their health but also their children. This research was designed to assess the family function of children who were affected by parent's alcohol drinking. METHODS: Questionnaire survey was performed on 208 high school students (129 males and 79 females) in Daejeon from March to April, 2005. We defined the students whose CAST (Children of Alcoholics Screening Test) score was 6 or more as children of alcoholics (COA) group. Then, we evaluated the family function by family APGAR score between the COA group and the control group. RESULTS: Among the total, 36 (27.9%) male and 27 (34.1%) female students were in COA group. There was a significant (P<0.01) negative correlation between the CAST score and the family APGAR score in all students. In boys, there was no significant correlation between the CAST score and the family APGAR score, but in girls, there was significant negative correlation (P<0.01). Mean family APGAR score of the COA group was significantly (P<0.05) lower than that of the control group in all students. In boys, there was no significant difference, but in girls, the COA group's family APGAR score was significantly lower than the control group's score (P<0.05). CONCLUSION: The high school students, especially girl students, who were affected by parent's alcohol drinking showed a lower family APGAR score. Therefore, family physicians need to evaluate the family function when encountering students similar to COA group.
Alcohol Drinking
;
Alcoholics*
;
Apgar Score
;
Child*
;
Female
;
Humans
;
Male
;
Mass Screening*
;
Physicians, Family
;
Surveys and Questionnaires
5.Clinical Analysis of Diverticulosis of the Cecum and Ascending Colon.
Gyu Yeol KIM ; Chang Woo NAM ; Byung Kyun KO ; Hong Rae CHO ; Chan Jin PARK ; Dae Hwan CHOI
Journal of the Korean Society of Coloproctology 1998;14(3):595-604
BACKGROUND: Diverticulosis of the cecum and ascending colon is a rare disease in Western countries, it is more common in the Orient. Making the diagnosis preoperatively could be difficult, and the intraoperative assessment and decision of optimal treatments are difficult. METHODS: Therefore, we reviewed the patient's charts of diverticulosis of the cecum and ascending colon at our hospital from 1992 to 1997. RESULTS: During the past 5 years, a total of 53 cases of diverticulosis of the cecum and ascending colon had been treated at this hospital. Mean age was 41.8 years (range 20-70). The male to female ratio was 1.8 : 1. Frequent complaints were abdominal pain (46 cases, 86.8%), followed by diarrhea (5 cases, 9.3%), indigestion (4 cases, 7.5%), and bowel habits change (2 cases, 3.8%). Mean duration of illness was 3.5 days(range 24 hours~15 days). In non-surgical cases, diagnoses were established with barium enema, CT scan, or ultrasonography. The accuracy of these methods was 91%, 75%, and 25%. In surgical cases, the preoperative diagnoses were appendicitis(13 cases, 50.1%), diverticulitis (7 cases, 31.8%), and abscess (2 cases, 9.1%). Treatments of the cecum and ascending colon diverticulitis were conservative management (3 teases,58.5%) and surgical treatment (22 cases,41.5%). The operative procedures were right hemicolectomies (2 cases), ileocecal resections (2 cases), diverticulectomies (6 cases) and appendectomies only (11 cases). CONCLUSION: These results suggest that correct diagnosis of the diverticulitis of the cecum and ascending colon made before treatment is very important because correct assessment of diverticulitis intraoperatively is difacut. Liberal use of diagnostic modalities could facilitate to make correct diagnosis to set a proper plan for treatment.
Abdominal Pain
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Abscess
;
Appendectomy
;
Barium
;
Cecum*
;
Colon, Ascending*
;
Diagnosis
;
Diarrhea
;
Diverticulitis
;
Diverticulum*
;
Dyspepsia
;
Enema
;
Female
;
Humans
;
Male
;
Rare Diseases
;
Surgical Procedures, Operative
;
Tomography, X-Ray Computed
;
Ultrasonography
6.Analysis of fMRI Signal Using Independent Component Analysis.
Chan Hong MOON ; Dong Gyu NA ; Hyun Wook PARK ; Jae Wook RYOO ; Eun Jung RHEE ; Hong Sik BYUN
Journal of the Korean Society of Magnetic Resonance in Medicine 1999;3(2):188-196
The fMRI signals are composed of many various signals. It is very difficult to find the accurate parameter for the model of fMRI signal containing only neural activity, though we may estimating the signal patterns by the modeling of several signal components. Besides the nose by the physiologic motion, the motion of object and noise of MR instruments make it more difficult to analyze signals of fMRI. Therefore, it is not easy to select an accurate reference data that can accurately reflect neural activity, and the method of an analysis of various signal patterns containing the information of neural activity is an issue of the post-processing methods for fMRI. In the present study, fMRI data was analyzed with the Independent Component Analysis(ICA) method that doesn't need a priori-knowledge or reference data. ICA can be more effective over the analytic method using cross-correlation analysis and can separate the signal patterns of the signals with delayed response or motion related components. The Principal Component Analysis (PCA) threshold, wavelet spatial filtering and analysis of a part of whole images can be used for the reduction of the freedom of data before ICA analysis, and these preceding analyses may be useful for a more effective analysis. As a result, ICA method will be effective for the analysis of signal patterns in fMRI and the pre-filtering may be necessary for the reduction of the degree of freedom of the data.
Freedom
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Magnetic Resonance Imaging*
;
Noise
;
Nose
;
Principal Component Analysis
7.A Study of Optimal SOAmin for Motor and Language Tasks in Event-related fMRl using Stochastic Design.
Chan Hong MOON ; Jae Wook RYOO ; Dong Gyu NA ; Eung Jung RHEE ; Hong Sik BYUN
Journal of the Korean Society of Magnetic Resonance in Medicine 2002;6(1):28-34
PURPOSE: The minimum stimulus onset asynchronoy(SOAmin) is one of important experimental parameters for an event-related fMRl experiment designed with the stochastic stimulus. In this study, the most efficient SOAmin is explored for the stronger activation in motor and language tasks with the stimulus designed stochastically. MATERIALS AND METHODS: The event-related fMRl during motor and language tasks were obtained in four normal right-handed subjects. EPI-BOLD sequence is used at 1.5 Tesla MR system for the acquisition of event-related fMRl. For each task the subjects are responded for the stimulus' with 2, 3, 4, and 6 seconds SOAmin. The obtained images are processed with SPM99, and the p value is set as 0.05 for the significant activation detection. The Z value and the number of activated pixels are compared for each task. RESULTS: For the motor task, the primary and supplementary motor areas are activated, and for the language task the consistent activated signals are detected in the Broca's. The activated signal is to be stronger for the shorter SOAmin for both motor and language tasks. At primary motor area, the activated signals is the strongest for 3 seconds SOAmin and for the supplementary motor area the result with 2 seconds SOAmin shows the strongest activation. And the result of language task shows the strongest activation at the 2 seconds SOAmin. CONCLUSION: In the event-related fMRl of motor and language tasks with the stochastically designed stimulus, the 2 or 3 seconds SOAmin is efficient for more activated and clustered activation.
8.Influence of Early Age at Menopause on Bone Mineral Density and Biochemical Bone Marker.
Young Joo PARK ; Chan Soo SHIN ; Do Joon PARK ; Jung Koo KIM ; Sung Yeon KIM ; Bo Yeon CHO ; Hong Gyu LEE ; Jae Hyun KIM ; In Kyung CHUNG
Journal of Korean Society of Endocrinology 1999;14(2):346-354
BACKGROUND: Among the various factors affecting bone mass and bone metabolism, aging and menopause play a major role. After the disappearance of the menstrual cycle, estrogen deficiency is the most important factor in bone loss. It is still unclear whether women with early menopause have a rate of bone loss different from women whose menopause has occurred later. Various biochemical bone markers are increased after menopause but it is still unclear whether women with early menopause have biochemical bone markers different from women whose menopause has occurred later. The aim of this study was to establish whether healthy women with early or normal menopause have different bone mass, biochemical bone markers and rates of bone loss. METHODS: Postmenopausal healthy women were divided into two groups according to their age at menopause(AAM): one group with AAM > 43 years, and the other group with AAM 50 years. Bone mass was measured using a dual energy X-ray absorptiometry(DEXA) in the lumbar, femur neck, femur trochanter, and Wards triangle. Serum levels of bone alkaline phosphatase and osteocalcin, and urine levels of calcium, deoxypyridinoline and type I collagen N-telopeptide were measured using a commercial kit. RESULTS: Age and body mass index in the early menopause group were different from those in the normal menopause group. All the bone mass and the biochemical bone markers in the early menopause group were not different from those in the normal menopause group. We selected 15 subjects from the two groups matched by age and BML Bone mass of femur neck in the early menopause group was lower than in the normal menopause group matched by age and BMI. Bone mass in lumbar, femur trochanter, and Wards triangle was lower in the early menopause group than in the normal menopause group, but the difference between the two groups was not significant. After adjusting years since menopause, we didnt find the difference of bone mass between the two groups. All the bone biochemical markers were not different in the two groups matched by age and BMI. CONCLUSION: Our data suggest that women with early menopause dont lose bone faster than women with normal menopause.
Aging
;
Alkaline Phosphatase
;
Biomarkers
;
Body Mass Index
;
Bone Density*
;
Calcium
;
Collagen Type I
;
Estrogens
;
Female
;
Femur
;
Femur Neck
;
Humans
;
Menopause*
;
Menstrual Cycle
;
Metabolism
;
Osteocalcin
9.Two Cases of Successful Surgical Treatment of Postmyocardial Infarction Ventricular Septal Defect-Repeated Performation After the First Operation.
Ji Hyun LEE ; Byung Gyu NA ; Sang Woo OH ; Gi Byoung NAM ; Dong Woon KIM ; Myeong Chan CHO ; Youn Woo NO ; Jong Myun HONG ; Jae Ho AN
Korean Circulation Journal 1997;27(2):234-240
Mechanical complications of acute myocardial infarction which may lead to heart failure or shock include ruptute of left ventricular free wall, ventricular septum and papillary muscle. The clinical characteristics of these lesions vary conservative management alone has high mortality rate, for which reason surgical repair of these defects are essential. Structural defects including rupture of the left ventricular free wall, ventricular septum, and papillary muscle, accout for 5% to 20% of all deaths from acute myocardial infarction. Among these, ventricular septal defects occur in approximately 1% of all myocardial infarction, and account for up to 2% of deaths subsequent to myocardial infarction. Rupture of the ventricular septum following acute myocardial infarction(AMI) is associated with high mortality rate, as 54% of the patients succumb within two weeks, 87% within two months and 92.5% during the first year. We experienced two cases of postinfarct ventricular septal defects(VSD) which had been repaired within 1 week after AMI due to progressive deterioration of patients` conditions, and were to be reoperated because of repeated septal ruptures in postoperation period and development of cardiogenic shock.
Heart Failure
;
Heart Septal Defects, Ventricular
;
Humans
;
Infarction*
;
Mortality
;
Myocardial Infarction
;
Papillary Muscles
;
Rupture
;
Shock
;
Shock, Cardiogenic
;
Ventricular Septum
10.Assessment of Imaging Distortion in Magnetic Resonance Imaging for Stereotactic Radiosurgery: Through Phantom Study.
Sun Won PARK ; Moon Hee HAN ; Dong Gyu KIM ; Hyun Tai CHUNG ; In Chan SONG ; Hong Dae KIM ; Kee Hyun CHANG
Journal of the Korean Society of Magnetic Resonance in Medicine 2000;4(1):7-13
PURPOSE: To assess the distortion of MRI with the Leksell stereotactic radiosurgery system in variable pulse sequence and imaging plane through phantom study, to find most adequate imaging plane and pulse sequence for stereotactic radiosurgery system. MATERIALS AND METHODS: We made the phantoms for MRI and get images in variable conditions and analyzed the image distortion using image analysis program, and statistically using paired student t-test. RESULTS: The transeverse plane images had acceptable error ranges (less than 1.5mm) in all pulse sequence in both the analysis of fiducial marker in stereotactic G-frame and the phantom study. The coronal plane images had unacceptable large errors (more than 1.5mm) in the analysis of fiducial marker in the stereotactic G-frame, but had corrected small errors (less than 1.5mm) in the phantom study. CONCLUSION: We find from the phantom study that the present MR machines are adequate for stereotactic surgery system in frequently used pulse sequences, and imaging planes.
Fiducial Markers
;
Humans
;
Magnetic Resonance Imaging*
;
Radiosurgery*