No abstract available.
Cross Infection*

The authors examined 9 condylomas, 26 cervical intraepithelial neoplasms(CIN) and 22 invasive squamous cell carcinomas for the presence of human papillomavirus(HPV) DNA sequences by DNA-DNA in situ hybridization. In situ hybridization revealed target HPV DNA sequences mostly in the nuclei of the superficial cells from epithelium which contained either maturation or koilocytotic atypias. With the use of biotinylated HPV DNA probes 6/11, 16/18 and 31/33/35, 42 of the 57(73.7%) were positive with HPV-6/11, 23 with HPV-16/18, 32 with HPV-31/33/35 and 18 with two or more mixed probes. HPV-31/33/35 was wht most prevalent in CIN and invasive squamous cell carcinomas, follwed by HPV-16/18. The incidence of HPV DNA increased from 66.7% to 86.4% with increasing severity of the lesions from condylomas to invasive squamous cell carcinomas. Flat condyloma was most freuently accompanied by CIN.
Humans ; Incidence

Tensiomyography (TMG) is known as non-invasive method which assesses the muscular characteristics such as contraction velocity or maximal displacement of the belly. The aim of this study was to evaluate muscular responses by TMG after muscle injury and to introduce using TMG first in Korea. This study was performed with a subject who was diagnosed with muscular injury and consent measuring and following up TMG analyses. A female patient, who was diagnosed left hip adductor muscle strain, underwent magnetic resonance imaging (MRI) and TMG at intervals of two weeks. We obtained decreased in displace maximum (Dm, 4.14 vs. 5.69) and altered curve shape in the injured muscle at the initial TMG assessment in comparison to the non-injured side. After two weeks, MRI findings and symptom were improved and Dm in the injured side increased as in the non-injured muscle. These findings suggest that a decrease in Dm indicate increased in muscle stiffness after muscle injury, and an increase in Dm as in the non-injured side after two weeks indicate recovered status. TMG may be useful as a simple and non-invasive device for monitoring muscle function after muscle injury and during the recovery.
Female ; Hip ; Humans ; Korea ; Magnetic Resonance Imaging

Recurrence in patients with superficial bladder tumor is a serious problem. In one series, the recurrence rate was 73%, and invasive cancer developed in 10% of patients with recurrences. To eliminate or reduce the rate of recurrence, topical chemotherapy has been tried and showed adjunct effects. We studied to evaluate prophylactic effects of topical chemotherapy in 51 patients with superficial bladder tumor admitted to the Department of Urology, Kyung Hee University Hospital during the period from April, 1979 to April, 1984. Patients were divided into 2 groups. Group A comprised 19 patients (Adriamycin; 8, Thio-TEPA; 11) treated with topical chemotherapy following initial TUR and 27 patients treated by TUR only. Group B comprised 5 patients treated with topical chemotherapy (Adriamycin) after repeated TUR and 7 patients among 27 patients who had repeated TUR for recurrence. Patients treated by TUR only were defined as control group. Recurrence rate was analyzed in each group. Following results were obtained. 1. In group A, recurrence rate was 2.54 in patients with chemotherapy comparing to 3.35 in control patients. Average interval of recurrence was 39.3 months in chemotherapy patients and 29.8 months in control patients. 2. In group B, recurrence rate was higher in chemotherapy patients than in control patients with rate of 6.6 and 5.3, respectively. But recurrence rate was diminished to 6.6 after chemotherapy comparing to pre-chemotherapy period (10.3). 3. There was no difference in recurrence rate relating to multiplicity of tumor as a whole.
Drug Therapy* ; Humans ; Recurrence ; Thiotepa ; Urinary Bladder Neoplasms* ; Urinary Bladder* ; Urology

BACKGROUND: There are cases in which shoulder pain persists long after shoulder joint surgery and this pain can not be reduced by intravenous patient controlled analgesia (IVPCA). Our purpose was to evaluate the effect of stellate ganglion block (SGB) on postoperative shoulder pain and also to investigate the effect of preventive SBG on complex regional pain syndrome (CRPS). METHODS: Forty patients, who were evaluated to ASA class 1 and 2 and who were scheduled for shoulder joint surgery under general anesthesia, were randomly divided into 2 groups. The experimental group of patients (n = 20) received SGB with 0.5% mepivacaine 8 ml after induction of general anesthesia. The control group of patients (n = 20) received only general anesthesia. Their postoperative pain was assessed using the visual analog scale (VAS) at 30 min, 1, 2, 6, 12, 24 and 48 hours postoperatively. Whenever patients wanted supplemental analgesia, diclofenac sodium 75 mg was injected intramuscularly and the need for supplemental analgesia was recorded. RESULTS: The experimental group of patients had significantly lower pain scores at 30 min, 1, 2 and 6 hours and also significantly lower analgesic requirement at 1, 2 and 6 hours. CONCLUSIONS: We found SGB was effective for controlling postoperative pain after shoulder joint surgery. Also, we could expect that SGB reduced the incidence of CRPS.
Analgesia ; Analgesia, Patient-Controlled ; Anesthesia, General ; Diclofenac ; Humans ; Incidence ; Mepivacaine ; Pain, Postoperative* ; Shoulder Joint* ; Shoulder Pain ; Shoulder* ; Stellate Ganglion* ; Visual Analog Scale