1.Self-expandable Graft Stenting in an Iatrogenic Fistula between Common Carotid Artery and Internal Jugular Vein.
Sung Chul JIN ; Dong Hyuk LEE ; Chae Wook HUH
Journal of Cerebrovascular and Endovascular Neurosurgery 2017;19(3):213-216
A 47-year-old woman with stage IV chronic kidney disease developed a fistula between common carotid artery (CCA) and internal jugular vein (IJV) during central catheterization of the right IJV. The patient was treated with a self-expandable graft stent, which achieved successful closure of the carotid-jugular fistula. As demonstrated in our case, self-expandable graft stents could be a feasible treatment option for CCA-IJV fistulas without additional interventional procedures such as balloon angioplasty.
Angioplasty, Balloon
;
Carotid Artery, Common*
;
Catheterization, Central Venous
;
Female
;
Fistula*
;
Humans
;
Jugular Veins*
;
Middle Aged
;
Renal Insufficiency, Chronic
;
Stents*
;
Transplants*
2.Therapeutic effect of transarterial chemoembolization using cisplatin-lipiodol mixture in hepatocelluar carcinoma.
Mi Sun KIM ; Ki Bum CHO ; Moo In PARK ; In Ki WOO ; Soo Jung LEE ; Sang Wook LEE ; Byung Hoon HAN ; Byung Chae PARK ; Jin Do HUH ; Young Duk CHO
Journal of the Korean Cancer Association 1993;25(4):494-500
No abstract available.
3.Endosaccular Treatment of Very Large and Giant Intracranial Aneurysms with Parent Artery Preservation: Single Center Experience with Long Term Follow-up
Chae Wook HUH ; Jae Il LEE ; Chang Hwa CHOI ; Tae Hong LEE ; Jae Young CHOI ; Jun Kyeung KO
Journal of Korean Neurosurgical Society 2018;61(4):450-457
OBJECTIVE: Very large (20–25 mm) and giant (≥25 mm) intracranial aneurysms have an extremely poor natural course, and treatment of these aneurysms remains a challenge for endovascular and surgical strategies. This study was undertaken to describe our experiences of endosaccular treatment of very large and giant intracranial aneurysms with parent artery preservation.METHODS: From January 2005 to October 2016, twenty-four very large or giant aneurysms in 24 patients were treated by endosaccular coil embolization with parent artery preservation. Nine (37.5%) aneurysms were ruptured and 15 were unruptured, and of these 15, 11 were symptomatic cases and 4 were incidentally discovered. The cohort comprised 17 women and 7 men of mean age 58.5 years (range, 26–82). Mean aneurysm size was 26.0 mm (range, 20–39) and 13 of the 24 aneurysms were giant.RESULTS: Immediate angiographic results were complete occlusion in nine (37.5%) cases, remnant neck in six (25.0%), and remnant sac in nine (37.5%). Overall procedural related morbidity and mortality rates were 12.5% and 4.2%, respectively. Angiographic follow-up was available in 16 patients (66.7%). Mean and median follow-up periods were 27.2 (range, 2–77) and 10.5 months, respectively. In 12 cases (12/16, 75%) stable occlusion was achieved, four cases (4/16, 25%) had recanalized, and two of these were retreated with additional coiling. At clinical follow-up of the nine ruptured cases, three patients (33.3%) achieved a good clinical outcome (Glasgow outcome scale [GOS] score of 4 or 5), two (22.2%) a poor outcome (GOS score of 2 or 3), and four patients (44.4%) expired (GOS 1). On the other hand, of the 15 unruptured cases, 13 patients (86.7%) achieved a good clinical outcome (GOS 4 or 5), one patient a poor outcome (GOS score of 2 or 3), and one patient expired (GOS 1).CONCLUSION: The present study shows endosaccular treatment of very large or giant intracranial aneurysms with parent artery preservation is both feasible and effective with acceptable morbidity and mortality.
Aneurysm
;
Arteries
;
Cohort Studies
;
Embolization, Therapeutic
;
Female
;
Follow-Up Studies
;
Hand
;
Humans
;
Intracranial Aneurysm
;
Male
;
Mortality
;
Neck
;
Parents
4.Feasibility and efficacy of coil embolization for middle cerebral artery aneurysms
Jae Young CHOI ; Chang Hwa CHOI ; Jun Kyeung KO ; Jae Il LEE ; Chae Wook HUH ; Tae Hong LEE
Yeungnam University Journal of Medicine 2019;36(3):208-218
BACKGROUND: The anatomy of middle cerebral artery (MCA) aneurysms has been noted to be unfavorable for endovascular treatment. The purpose of this study was to assess the feasibility and efficacy of coiling for MCA aneurysms.METHODS: From January 2004 to December 2015, 72 MCA aneurysms (38 unruptured and 34 ruptured) in 67 patients were treated with coils. Treatment-related complications, clinical outcomes, and immediate and follow-up angiographic outcomes were retrospectively analyzed.RESULTS: Aneurysms were located at the MCA bifurcation (n=60), 1st segment (M1, n=8), and 2nd segment (M2, n=4). Sixty-nine aneurysms (95.8%) were treated by neck remodeling techniques using multi-catheter (n=44), balloon (n=14), stent (n=8), or combination of these (n=3). Only 3 aneurysms were treated by single-catheter technique. Angiographic results were 66 (91.7%) complete, 5 (6.9%) remnant neck, and 1 (1.4%) incomplete occlusion. Procedural complications included aneurysm rupture (n=1), asymptomatic coil migration to the distal vessel (n=1), and acute thromboembolism (n=10) consisting of 8 asymptomatic and 2 symptomatic events. Treatment-related permanent morbidity and mortality rates were 4.5% and 3.0%, respectively. There was no bleeding on clinical follow-up (mean, 29 months; range, 6-108 months). Follow-up angiographic results (mean, 26 months; range, 6-96 months) in patients included 1 major and 3 minor recanalizations.CONCLUSION: Coiling of MCA aneurysms could be a technically feasible and clinically effective treatment strategy with acceptable angiographic and clinical outcomes. However, the safety and efficacy of this technique as compared to surgical clipping remains to be ascertained.
Aneurysm
;
Embolization, Therapeutic
;
Follow-Up Studies
;
Hemorrhage
;
Humans
;
Intracranial Aneurysm
;
Middle Cerebral Artery
;
Mortality
;
Neck
;
Retrospective Studies
;
Rupture
;
Stents
;
Surgical Instruments
;
Thromboembolism
5.Feasibility and efficacy of coil embolization for middle cerebral artery aneurysms
Jae Young CHOI ; Chang Hwa CHOI ; Jun Kyeung KO ; Jae Il LEE ; Chae Wook HUH ; Tae Hong LEE
Yeungnam University Journal of Medicine 2019;36(3):208-218
BACKGROUND:
The anatomy of middle cerebral artery (MCA) aneurysms has been noted to be unfavorable for endovascular treatment. The purpose of this study was to assess the feasibility and efficacy of coiling for MCA aneurysms.
METHODS:
From January 2004 to December 2015, 72 MCA aneurysms (38 unruptured and 34 ruptured) in 67 patients were treated with coils. Treatment-related complications, clinical outcomes, and immediate and follow-up angiographic outcomes were retrospectively analyzed.
RESULTS:
Aneurysms were located at the MCA bifurcation (n=60), 1st segment (M1, n=8), and 2nd segment (M2, n=4). Sixty-nine aneurysms (95.8%) were treated by neck remodeling techniques using multi-catheter (n=44), balloon (n=14), stent (n=8), or combination of these (n=3). Only 3 aneurysms were treated by single-catheter technique. Angiographic results were 66 (91.7%) complete, 5 (6.9%) remnant neck, and 1 (1.4%) incomplete occlusion. Procedural complications included aneurysm rupture (n=1), asymptomatic coil migration to the distal vessel (n=1), and acute thromboembolism (n=10) consisting of 8 asymptomatic and 2 symptomatic events. Treatment-related permanent morbidity and mortality rates were 4.5% and 3.0%, respectively. There was no bleeding on clinical follow-up (mean, 29 months; range, 6-108 months). Follow-up angiographic results (mean, 26 months; range, 6-96 months) in patients included 1 major and 3 minor recanalizations.
CONCLUSION
Coiling of MCA aneurysms could be a technically feasible and clinically effective treatment strategy with acceptable angiographic and clinical outcomes. However, the safety and efficacy of this technique as compared to surgical clipping remains to be ascertained.
6.The Impact of Engorged Vein within Traumatic Posterior Neck Muscle Identified in Preoperative Computed Tomography Angiography to Estimated Blood Loss during Posterior Upper Cervical Spine Surgery.
Mahn Jeong HA ; Byung Chul KIM ; Chae Wook HUH ; Jae Il LEE ; Won Ho CHO ; Hyuk Jin CHOI
Korean Journal of Neurotrauma 2016;12(2):135-139
OBJECTIVE: Injuries of upper cervical spine are potentially fatal. Thus, appropriate diagnosis and treatment is essential. In our institute, preoperative computed tomography angiography (CTA) has been performed for evaluation of injuries of bony and vascular structure. The authors confirmed the engorged venous plexus within injured posterior neck muscle. We have this research to clarify the relationship between the engorged venous plexus and engorged vein. METHODS: A retrospective review identified 23 adult patients who underwent 23 posterior cervical spine surgeries for treatment of upper cervical injury between 2013 and 2015. Preoperative CTA was used to identify of venous engorgement within posterior neck muscle. The male to female ratio was 18:5 and the mean age was 53.5 years (range, 25-78 years). Presence of venous engorgement and estimated blood loss (EBL) were analyzed retrospectively. RESULTS: The EBL of group with venous engorgement was 454.55 mL. The EBL of group without venous engorgement was 291.67 mL. The EBL of group with venous engorgement was larger than control group in significant. CONCLUSION: The presence of engorged venous plexus is important factor of intraoperative bleeding. Preoperative CTA for identifying of presence of engorged venous plexus and fine operative techniques is important to decrease of blood loss during posterior cervical spine surgery.
Adult
;
Angiography*
;
Blood Loss, Surgical
;
Diagnosis
;
Female
;
Hemorrhage
;
Humans
;
Hyperemia
;
Male
;
Neck Muscles*
;
Neck*
;
Retrospective Studies
;
Spinal Injuries
;
Spine*
;
Veins*
7.A case of chronic diarrhea caused by duodenocolic fistula.
Jeong KIM ; Je Wook CHAE ; Hyun Joo SUH ; Jun Haeng LEE ; Young Ho KIM ; Jong Chul RHEE ; Jin Suk HUH
Korean Journal of Medicine 2004;67(Suppl 3):S718-S721
The four basic mechanisms that cause chronic diarrhea are osmotic, secretory and exudative factors, and abnormal intestinal transit. A gastrointestinal fistula cause chronic diarrhea by abnormal intestinal transit, and it must be included differential diagnosis for unknown cause of chronic diarrhea. Duodenocolic fistula is an uncommon cause of chronic diarrhea. The most common cause of duodenocolic fistula is a colon cancer. Benign duodenocolic fistula is a rare disease, which the most common cause is a duodenal ulcer. Patients usually complain of diarrhea, weight loss. Physical examinations are nonspecific. Barium enema is the most useful diagnostic procedure. Prognosis is good if surgery is undertaken at an early stage. We present a case of a 66-years old man in whom a duodenocolic fistula maybe caused by recurrent microperforation of duodenal ulcer. He complained of chronic diarrhea and weight loss. He had an operation on his fistula, and remained well.
Aged
;
Barium
;
Colonic Neoplasms
;
Diagnosis, Differential
;
Diarrhea*
;
Duodenal Ulcer
;
Enema
;
Fistula*
;
Humans
;
Physical Examination
;
Prognosis
;
Rare Diseases
;
Weight Loss
8.Post Traumatic Pseudoaneurysm Arising from V4 Segment of Vertebral Artery: A Case Report.
Chae Wook HUH ; Kyoung Hyup NAM ; Chang Hwa CHOI ; Jae Il LEE
Korean Journal of Neurotrauma 2015;11(2):154-157
This case report describes a traumatic pseudoaneurysm arising from the right V4 segment of the vertebral artery, near the origin of the posterior inferior cerebellar artery. Post-traumatic vertebral artery pseudoaneurysm is rare, but associated with a high mortality rate. We report on an extremely rare case of post-traumatic pseudoaneurysm of the vertebral artery with delayed manifestation. A 9-year-old child was admitted to the emergency room after a pedestrian car accident. A computed tomography (CT) scan showed subarachnoid hemorrhage with intraventricular hemorrhage (IVH), multiple facial bones, and temporal bone fracture. External ventricular drainage and decompressive suboccipital craniectomy were performed for acute hydrocephalus and posterior fossa swelling. The patient's clinical condition became suddenly aggravated on the 15th hospital day, and brain CT confirmed appearance of a new 4th ventricle IVH. Digital subtraction angiography revealed a ruptured pseudoaneurysm arising from the right V4 segment of the vertebral artery. Parent artery occlusion using detachable coils was achieved. Despite intensive care, the patient's clinical condition showed continuous deterioration and the patient died of respiratory complications on the 52nd hospital day.
Aneurysm, False*
;
Angiography, Digital Subtraction
;
Arteries
;
Brain
;
Child
;
Craniocerebral Trauma
;
Drainage
;
Emergency Service, Hospital
;
Facial Bones
;
Hemorrhage
;
Humans
;
Hydrocephalus
;
Critical Care
;
Mortality
;
Parents
;
Subarachnoid Hemorrhage
;
Temporal Bone
;
Vertebral Artery*
9.Diagnostic Yield of Tissue Sampling Using a Bite-On-Bite Technique for Incidental Subepithelial Lesions.
Jeong Seon JI ; Bo In LEE ; Kyu Yong CHOI ; Byung Wook KIM ; Hwang CHOI ; Min HUH ; Woo Chul CHUNG ; Hiun Suk CHAE ; In Sik CHUNG
The Korean Journal of Internal Medicine 2009;24(2):101-105
BACKGROUND/AIMS: Techniques for endoscopic evaluation of gastrointestinal subepithelial lesions include conventional endoscopy, jumbo biopsy, endoscopic ultrasonogrphy (EUS), EUS-guided fine needle aspiration, and endoscopic submucosal resection. However, these procedures have many limitations, such as low diagnostic yields and high complication rates. We therefore evaluated the diagnostic yield for tissue sampling of incidental subepithelial lesions using the bite-on-bite technique. METHODS: One hundred and forty subepithelial lesions were found in 129 patients during conventional diagnostic esophagogastroduodenoscopy by one examiner from October 2003 to November 2004. Bite-on-bite biopsies with conventional-sized forceps were taken from 36 patients having 37 lesions that did not appear to be hypervascular or to have a thick overlying epithelium. Two to eight bites were performed to obtain submucosal tissue for one lesion. RESULTS: The bite-on-bite technique was diagnostic in 14 of the 37 lesions (38%). Blood oozing for more than 30 seconds occurred in five cases, but was easily controlled by epinephrine injection (2 cases) or hemoclip (3 cases). The diagnostic yield tended to be higher in the esophagus than in the stomach and duodenum (54% vs. 28%, p=0.109). CONCLUSIONS: The bite-on-bite technique for subepithelial lesions is an effective and safe method in selected cases. This technique may be useful for incidental subepithelial lesions, especially those of the esophagus, except for ones with a high risk of bleeding or thick overlying epithelium.
Adult
;
Aged
;
Biopsy/adverse effects/instrumentation/*methods
;
Duodenum/*pathology
;
*Endoscopy, Digestive System/adverse effects
;
Esophagus/*pathology
;
Female
;
Gastric Mucosa/pathology
;
Hemorrhage/etiology/prevention & control
;
Hemostatic Techniques
;
Humans
;
*Incidental Findings
;
Intestinal Mucosa/pathology
;
Male
;
Middle Aged
;
Predictive Value of Tests
;
Prospective Studies
;
Stomach/*pathology
;
Surgical Instruments
10.The Effect of Oral Administration of Black Sticky Rice with Giant Embryo on Brain GABA Concentrations
Woo Young JUNG ; Sung Gon KIM ; Hyeon Kyeong KIM ; Sung Young HUH ; Dae Wook KIM ; Dong Uk YOON ; Chae Ha YANG ; Hee Young KIM ; Eun Young JANG
Psychiatry Investigation 2019;16(8):615-620
OBJECTIVE: Black sticky rice with giant embryo (BSRGE) contains high GABA content and affects alcohol-related indices among social drinkers, and alcohol intake and anxiety-related behavior of mice. However, it is unknown whether the intake of BSRGE affects GABAergic activity of brain directly. The purpose of this study is to elucidate the effect of oral administration of BSRGE on brain GABA concentrations compared with commercially available GABA compound and regular feeds. METHODS: Twenty-one male C57BL/6 mice were assigned to BSRGE, a regular feed (AIN-76) lacking GABA, and a regular feed containing GABA compound. After feeding freely for 48 h, the cortex and striatum were separated from the brain. An enzyme-linked immunosorbent assay was conducted to measure GABA and glutamate concentrations in mouse brain. RESULTS: The GABA concentration of the BSRGE group was higher than that of regular feed and GABA compound group (p<0.001). However, the GABA compound group showed no significant difference from the regular feed group (p=0.50). CONCLUSION: Intake of BSRGE containing high GABA content increased GABA concentrations in mouse brain compared with regular feed unlike GABA compound. The results of this study constitute an important basis for further investigations into the clinical applications of BSRGE.
Administration, Oral
;
Animals
;
Brain
;
Embryonic Structures
;
Enzyme-Linked Immunosorbent Assay
;
gamma-Aminobutyric Acid
;
Glutamic Acid
;
Humans
;
Male
;
Mice