1.Prognostic significance of DNA ploidy in colorectal cancer.
Chae Yong LIM ; Kwon Mook CHAE
Journal of the Korean Surgical Society 1991;41(4):467-472
No abstract available.
Colorectal Neoplasms*
;
DNA*
;
Ploidies*
2.Immunohistochemical and Ultrastructural Observation on Small Round Cell Tumors.
Chae Hong SUH ; Jeong Yeol YANG ; Sung Chul LIM ; Yong Lim KIM
Korean Journal of Pathology 1997;31(11):1200-1213
Small round cell tumors such as neuroblastoma, rhabdomyosarcoma, Ewing's tumor, malignant lymphoma and small cell carcinoma are often confused clinically and histologically. To clarify the similarites and differences and to get more information on the histogenesis among the small round cell tumors, we examined histological, immunohistochemical and ultrastructural features of ten cases of neuroblastomas, twenty Ewing's tumors, ten embryonal rhabdomyosarcomas and twelve small cell carcinomas in children and young adults. Antibodies against desmin, vimentin, cytokeratin, neuron-specific enolase, synaptophysin, neurofilament, S-100 protein, chromogranin and HBA 71 were used in biotin streptavidin procedures. The results of the immunohistochemical and electron microscopical examinations yielded virtually identical findings in each group as followings. 1) Among the twenty cases of Ewing's tumors, eighteen cases were positive in staining for HBA-71. The staining for HBA-71 was negative in neuroblastoma, embryonal rhabdomyosarcoma and small cell carcinoma. 2) Neuroblastomas had marked interdigitating cytoplasmic processes containing many microtubules and dense-core secretory granules, however, they were sparse and rare in Ewing's tumor. 3) Embryonal rhabdomyosarcoma showed actin-myosin bundles. According to differentiation, well differentiated rhabdomyosarcoma exhibited Z-band materials and external lamina. 4) Neuroblastoma showed ultrastructural evidence of a neuronal differentiation, but neuronal differentration is a sparse and rare in Ewing's tumor. This ultrastructural feature strengthens the hypothesis that Ewing's tumor is derived not only from an undifferentiated neuroectodermal stem cell but from primitive cell of neuroectodermal origin.
Antibodies
;
Biotin
;
Carcinoma, Small Cell
;
Child
;
Cytoplasm
;
Desmin
;
Humans
;
Immunohistochemistry
;
Keratins
;
Lymphoma
;
Microtubules
;
Neural Plate
;
Neuroblastoma
;
Neurons
;
Phosphopyruvate Hydratase
;
Rhabdomyosarcoma
;
Rhabdomyosarcoma, Embryonal
;
S100 Proteins
;
Sarcoma, Ewing
;
Secretory Vesicles
;
Stem Cells
;
Streptavidin
;
Synaptophysin
;
Vimentin
;
Young Adult
3.Iliac Crest Reconstruction after Harvesting Autogenous Iiac Bone Grafts for Anterior Spinal Fusion
Ki Soo KIM ; Yong Soo CHOI ; Chae In LIM ; Ssng Wook RYU ; Sun Yong JUNG
The Journal of the Korean Orthopaedic Association 1996;31(4):711-719
Potentially, some donor site complications are associated with the harvesting of autogenous tricortical iliac bone grafts for anterior spinal fusion. The purpose of this study was to evaluate the reliability of the anterior iliac crest reconstruction after harvesting autogenous iliac grafts for anterior spinal fusion. We devided into two groups : the study group were the anterior iliac crest reconstruction in 57 patients with minimal twelve months follow up period, the control group were not the anterior iliac crest reconstruction in 21 patients who could not obtain the rib from retroperitoneal approach. The average follow up was obtained at 43.3 months(12 to 72 months) in study group, at 41.6 months(12 to 60 months) in control group. The study group had a tendency to improve the donor site pain after incorporation of the rib graft and the control group tend to remain the donor site pain till late especially in the thinner group and combined disease group. In residual deformity of the donor site, the study group was superior to the control group. Residual deformity of the study group was associated with the complications such as displacement and resorption of the grafts. Cosmetic residual deformity tends to be higher in the thinner group. Radiographically all rib gragts incorporated in situ in 51 patients despite of some cases of migration(Average 11 weeks and 4 days) and clinical results did not affect by biological behavior of rib grafts on the follow up radiogram. The authors attempted anterior iliac crest reconstruction using the implants (Mennen plate in 3 patients, threaded pin in 3 patients) after large harvesting of autogenous tricortical graft in 6 patients who could not obtain the rib from retroperitoneal approach or could not fit the rib too the defect. In those cases the results were satisfactory clinically. These results suggest anterior iliac crest reconstruction can minimize painful deformity after the harvesting of autogenous tricortical iliac grafts for anterior spinal fusion.
Congenital Abnormalities
;
Follow-Up Studies
;
Humans
;
Ribs
;
Spinal Fusion
;
Tissue Donors
;
Transplants
4.The effect of Large for Gestational Age on Asymmetrical Ventricular Septal Hypertrophy in the Newborn.
Yong Soo KIM ; Soo Ahn CHAE ; In Seok LIM ; Byoung Hoon YOO
Journal of the Korean Society of Neonatology 1998;5(1):40-44
PURPOSE: It has been known for a long time that infants of insulin dependent diabetic mothers are prone to develop macrosornia, organomegaly, hyperbilirubinemia, respiratory distress syndrome, hypoglycemia, hypocalcemia, septicemia and congenital anomalies in the neonatal period. And echocardiographic asymmetrical- ventricular septal hyper- trophy(ASH) has been observed in the newborn infants of diabetic mothers. The etiology of the ASH remains unknown, although fetal hyperglycemia and subsequent glycogen deposits have been postulated as contributing factors. Therefore, we have studied whether large for gestational age(LGA) has played an important role of developing ASH. METHODS: We compared echocardiographic findings in neonates of LGA and appro- priate for gestational age(AGA), who were admitted to the Department of Pediatrics, Chung Ang University Hospital from April 1994 to March 1997. RESULTS: 1) Mean LVED in LGA and AGA were 1.96+0.06cm and 1.94+0.04cm, respectively. 2) Mean LVPW in LGA and AGA were 0.37+0.05cm and 0.370.05cm, respectively. 3) Mean IVS in LGA and AGA were 0.400.09cm and 0.380.09cm, respectively. 4) Mean IVS/ LVPW in LGA and AGA were 1.09+0.12 and 1.040.17, respectively. There was no statistical significance between two groups in echocardiographic findings. CONCLUSION: There is no relation between LGA and ASH in the neonate. According- ly, we may not need to perform echocardiography LGA routinely.
Echocardiography
;
Gestational Age*
;
Glycogen
;
Humans
;
Hyperbilirubinemia
;
Hyperglycemia
;
Hypertrophy*
;
Hypocalcemia
;
Hypoglycemia
;
Infant
;
Infant, Newborn*
;
Insulin
;
Mothers
;
Pediatrics
;
Sepsis
5.A Novel Method to Measure Superior Migration of the Humeral Head: Step-off of the C-line.
Kyoung Jin PARK ; Hyeon Jun EUN ; Yong Min KIM ; Jun Il YOO ; Chae Ouk LIM
Clinics in Shoulder and Elbow 2016;19(3):125-129
BACKGROUND: Superior migration of humeral head has been conventionally determined by measuring the acromiohumeral distance (AHD), We sought to devise a novel measurement system more reliably and accurately than AHD. We described a structural landmark called 'C-line'. In this study, we investigated the clinical usefulness of 'step-off of the C-line (SOC)' compared to that of AHD. METHODS: The C-line formed from the medial margin of the proximal humeral head continuing up to the inferior margin of the articular glenoid and then to the lateral border of the scapula. The superior migration of the humeral head triggered by a rotator cuff tear introduces a discontinuity in this C-line. We measured the distance of this discontinuity. We enrolled 144 patients who underwent a rotator cuff repair. We selected 58 controls who didn't have any cuff lesions apparent on magnetic resonance imaging. Using radiographs derived from standardized true anteroposterior views of the shoulder, we measured the SOC and the AHD. We used t-tests for statistical analyses. RESULTS: A rotator cuff tear was associated with an increase in SOC and a decrease in AHD. In control group, the mean SOC was 1.29 ± 1.71 mm and AHD was 9.71 ± 2.65 mm. In cuff tear group, the mean SOC was 3.15 ± 3.41 mm and AHD was 8.28 ± 1.76 mm. The mean SOCs of the patient group in relation to the mean SOC of the control group according to tear size, the SOCs of medium tear and lager groups showed statistically significant increase (p<0.05). CONCLUSIONS: The SOC may be a similarly effective to diagnose cuff tears of medium size and larger compared with AHD.
Humans
;
Humeral Head*
;
Magnetic Resonance Imaging
;
Methods*
;
Rotator Cuff
;
Scapula
;
Shoulder
;
Tears
6.A study on the medical care expenditure of the uterine cervix carcinoma by clinical stage and treatment modality.
Hyo Ki MIN ; Doo Chae JUNG ; Soo Yong CHOI ; Je Ho LEE ; Jae Kyu LIM
Korean Journal of Epidemiology 1992;14(2):160-174
No abstract available.
Cervix Uteri*
;
Female
;
Health Expenditures*
7.Notes on Species of the Laboulbeniales from Yunnan Province of China.
Mycobiology 2000;28(2):110-114
Six species of the genus Laboulbenia were collected from some regions of Yunnan Province, China, in July, 1994. They are as follows; Laboulbenia acupapi Spegazzini was collected on Abacetus submetallicus (Nietner) and Stenolophus iridicolor Redtenbacher. The host of this fungus has been only found on genus Acupalpus in the world so far, but it was newly found on genus Abacetus and Stenolophus. Laboulbenia anoplogenii Thaxter subsp. abaceti Santamaria was collected on Abacetus submetallicus (Nietner). Laboulbenia elaphri Spegazzini was collected on Nebria ochotica Sahlberg, but the host of this fungus has been only found on genus Elaphrus in the world so far. It was newly collected on genus Nebria. Laboulnebia flagellata Peyritsch was collected on Harpalus platynotus Bates and Platynus sculptipes (Bates). Laboulbenia polyphaga Thaxter was collected on Harpalus bungii Chaudoir. Laboulbenia vulgaris Peyritsch was collected on Bembidion misellum Harold and Bembidon scopulium (Kirby).
Beetles
;
China*
;
Fungi
8.A case of bone cryptococcosis in a patient with SLE.
Sang Won SHIN ; Sae Yong KANG ; Heung Jeong WOO ; Yoon Sang CHOI ; Woo Joo KIM ; Seung Chull PARK ; Chae Seung LIM ; Jun Mi KIM ; Yang Seuk CHAE
Korean Journal of Infectious Diseases 1991;23(3):201-206
No abstract available.
Cryptococcosis*
;
Humans
9.Posterior Lumbar Intebody Fusion with Unilateral Transpedicular Screw and Contralateral Translaminar Facet Screw Fixation in Lumbar Spinal Stenosis.
Ki Soo KIM ; Yong Soo CHOI ; Chae Hyun LIM ; Kyung Ho PARK
Journal of Korean Society of Spine Surgery 2007;14(3):171-177
STUDY DESIGN: A retrospective study. OBJECTIVES: To describe the surgical procedure and assess the results of an unilateral transpedicular screw and contralateral translaminar facet screw fixation in degenerative lumbar stenosis. SUMMARY OF LITERATURE REVIEW: A drawback of conventional lumbar fusion is the extensive soft-tissue destruction that is essential when inserting a screw and preparing the fusion bed. The development of a procedure that minimizes the tissue trauma without compromising the effectiveness of the conventional posterior lumbar interbody fusion (PLIF) should be pursued in lumbar spinal stenosis. MATERIALS AND METHODS: From August 2004 to November 2005, PLIF was performed on 25 consecutive patients who had lumbar spinal stenosis. Among them, 10 patients underwent with unilateral transpedicular screw and contralateral translaminar facet screw fixation (Group 1), and 15 patients underwent traditional bilateral transpedicular screw fixation (Group 2). The clinical and radiological results in the two groups were compared. RESULTS: The mean follow-up was 17.6 and 20.5 months in Groups 1 and 2, respectively. Group 1 had less blood loss, fewer transfusion requirements (P.0.05) in the surgical procedure, and less postoperative back pain (P.0.05). There was no significant difference between the two groups in the clinical results such as the VAS score for back pain and the Kirkadly-Willis criteria at the last follow-up, and the radiological results such as the changes in the disc height and interbody fusion. CONCLUSION: The PLIF with unilateral transpedicular screw and contralateral translaminar facet screw fixation in lumbar spinal stenosis has advantages over conventional PLIF of less soft tissue injury, and produces good clinical results.
Back Pain
;
Constriction, Pathologic
;
Follow-Up Studies
;
Humans
;
Retrospective Studies
;
Soft Tissue Injuries
;
Spinal Stenosis*
10.Posttraumatic Stress Disorder Among Occupational Accident Patients.
Kyeong Sook CHOI ; Chae Ki LIM ; Jae Wook CHOI ; Seong Kyu KANG ; Yong Tae YUM
Journal of Korean Neuropsychiatric Association 2002;41(3):461-471
OBJECTIVES: This study was conducted to assess the development of posttraumatic stress disorder (PTSD) after occupational physical injuries and the risk factors in occupational accident patients for PTSD. METHODS: Forty-seven occupational accident patients with physical injuries were administered BDI, STAI I and II, SCL-90-R, IES and questionnaires for risk factors and Clinician-Administered PTSD Scale(CAPS). RESULTS: 1) 12 patients(25%) were diagnosed as PTSD. 2) The BDI, STAI I and II and IES scores are significantly high(<0.05) in PTSD group than non-PTSD group. 3) The subscales of SCL-90-R, with an exception of PAR subscale, showed higher scores(<0.05) in PTSD group. 4) The loss of consciousness(LOC) was only significant risk factor in the occupational accident-related factors(<0.05). CONCLUSION: The results of this study show the development of PTSD among occupational accident patients. The loss of consciousness(LOC) was the only signiticant risk factor for PTSD in occupational accident patients.
Accidents, Occupational*
;
Humans
;
Surveys and Questionnaires
;
Risk Factors
;
Stress Disorders, Post-Traumatic*