1.A study on the medical care expenditure of the uterine cervix carcinoma by clinical stage and treatment modality.
Hyo Ki MIN ; Doo Chae JUNG ; Soo Yong CHOI ; Je Ho LEE ; Jae Kyu LIM
Korean Journal of Epidemiology 1992;14(2):160-174
No abstract available.
Cervix Uteri*
;
Female
;
Health Expenditures*
2.Notes on Species of the Laboulbeniales from Yunnan Province of China.
Mycobiology 2000;28(2):110-114
Six species of the genus Laboulbenia were collected from some regions of Yunnan Province, China, in July, 1994. They are as follows; Laboulbenia acupapi Spegazzini was collected on Abacetus submetallicus (Nietner) and Stenolophus iridicolor Redtenbacher. The host of this fungus has been only found on genus Acupalpus in the world so far, but it was newly found on genus Abacetus and Stenolophus. Laboulbenia anoplogenii Thaxter subsp. abaceti Santamaria was collected on Abacetus submetallicus (Nietner). Laboulbenia elaphri Spegazzini was collected on Nebria ochotica Sahlberg, but the host of this fungus has been only found on genus Elaphrus in the world so far. It was newly collected on genus Nebria. Laboulnebia flagellata Peyritsch was collected on Harpalus platynotus Bates and Platynus sculptipes (Bates). Laboulbenia polyphaga Thaxter was collected on Harpalus bungii Chaudoir. Laboulbenia vulgaris Peyritsch was collected on Bembidion misellum Harold and Bembidon scopulium (Kirby).
Beetles
;
China*
;
Fungi
3.Diagnosis of Malaria Using Automatic Hematology Analyzer.
Kyu Sung SHIN ; Kyung Ran MA ; Chae Seung LIM
Journal of Laboratory Medicine and Quality Assurance 2004;26(1):171-176
BACKGROUND: For the diagnosis of malaria, examination of blood smear slides by light microscopy is used as standard, and commercial kits detecting malarial antibodies and antigens are available, and molecular methods such as polymerase chain reaction (PCR) are used additionally. But, these diagnostic methods can be performed when clinicians request them, so problems of misdiagnosing the patients who are not suspected malaria may be occurred. METHODS: In 42 Korean patients with malaria, the author analyzed the characteristic signals of malaria using granularity (90 degrees depolarized) versus lobularity (90 degrees polarized) graph of Cell-Dyn 4000 (CD4000) automatic hematologic analyzer. And, the author examined the presence of malaria in 421 random samples by CD4000 and Giemsa stain. RESULTS: The usefulness of CD4000 in diagnosing malaria are as follows, 93.0% sensitivity, 99.3% specificity, 93.0% positive-predictive value, and 99.3% negative-predictive value. CONCLUSION: CD4000 automatic hematology analyzer has high diagnostic sensitivity and specificity in diagnosing malaria. Because complete blood count (CBC) is the routine test for most patients, this method has advantage of time and cost effectiveness and can even detect malaria in unsuspected cases.
Antibodies
;
Azure Stains
;
Blood Cell Count
;
Cost-Benefit Analysis
;
Diagnosis*
;
Hematology*
;
Humans
;
Malaria*
;
Microscopy
;
Polymerase Chain Reaction
;
Sensitivity and Specificity
4.Posttraumatic Stress Disorder Among Occupational Accident Patients.
Kyeong Sook CHOI ; Chae Ki LIM ; Jae Wook CHOI ; Seong Kyu KANG ; Yong Tae YUM
Journal of Korean Neuropsychiatric Association 2002;41(3):461-471
OBJECTIVES: This study was conducted to assess the development of posttraumatic stress disorder (PTSD) after occupational physical injuries and the risk factors in occupational accident patients for PTSD. METHODS: Forty-seven occupational accident patients with physical injuries were administered BDI, STAI I and II, SCL-90-R, IES and questionnaires for risk factors and Clinician-Administered PTSD Scale(CAPS). RESULTS: 1) 12 patients(25%) were diagnosed as PTSD. 2) The BDI, STAI I and II and IES scores are significantly high(<0.05) in PTSD group than non-PTSD group. 3) The subscales of SCL-90-R, with an exception of PAR subscale, showed higher scores(<0.05) in PTSD group. 4) The loss of consciousness(LOC) was only significant risk factor in the occupational accident-related factors(<0.05). CONCLUSION: The results of this study show the development of PTSD among occupational accident patients. The loss of consciousness(LOC) was the only signiticant risk factor for PTSD in occupational accident patients.
Accidents, Occupational*
;
Humans
;
Surveys and Questionnaires
;
Risk Factors
;
Stress Disorders, Post-Traumatic*
5.Clinical Analysis of Female Patients Under 20 Years of Age with Benign Breast Masses.
Man Kyu CHAE ; Chul Wan LIM ; Kyung Yul HUR ; Kyung Kyu PARK ; Min Hyuk LEE
Journal of the Korean Surgical Society 1999;56(1):43-48
BACKGROUND: Breast lesions in children and adolescents are rare and develop mainly in females. The management of breast masses in children and adolescents can be a perplexing problem for pediatricians and surgeons. It is well documented that breast lesions in females under 20 years of age rarely represent malignant disease. However, they frequently are a source of discomfort and anxiety for the patient, particularly when they do not resolve spontaneously. METHODS: To determine the frequency of different breast masses in females under 20 years of age on whom surgery was performed, we carried out a retrospective study of females under 20 years who were admitted to the Department. of Surgery of Soonchunhyang University Hospital for surgery between 1993 and 1995. RESULTS: The mean age was 17.9 years. A total of 44 surgical procedures were performed in 40 patients. The masses ranged in size from 0.8 cm through 7.0 cm. As to the location, the mass was in the right breast of 22 patients (50%) and in the left breast of 22 (50%). The most common location of the mass was in the right upper outer quadrant (13 patients, 29.5%). Of the 44 masses, fine-needle aspiration cytology was performed in 33 masses. Of them, 28 were fibroadenomas, 4 were fibrocystic disease, and 1 was a lipoma. Excisional biopsy was performed on 44 masses. Of them, 33 were fibroadenomas, 4 were fibrocystic disease, 5 was fibroadenoma and fibrocystic disease, 1 was a lipoma, and 1 was a lymphangioma. There were no malignancies. CONCLUSIONS: In female patients under 20 years of age, we suggest that benign breast should be studied for diagnosis, treatment, and histological feature.
Adolescent
;
Anxiety
;
Biopsy
;
Biopsy, Fine-Needle
;
Breast*
;
Child
;
Diagnosis
;
Female*
;
Fibroadenoma
;
Humans
;
Lipoma
;
Lymphangioma
;
Retrospective Studies
6.Serum Alkaline Phosphatase Levels in 10-20 Year Old Healthy Korean Children and Adolescents: Based on the 2009 Korean National Health and Nutrition Examination Survey.
Ji Young SEO ; Jeong Don CHAE ; Hong Kyu PARK ; Dong Ho KIM ; Jun Ah LEE ; Jung Sub LIM
Annals of Pediatric Endocrinology & Metabolism 2012;17(1):39-44
PURPOSE: Serum alkaline phosphatase (sALP) levels show great variation with age and sex in children and adolescents. We aimed to study pediatric age- and sex-specific reference ranges for sALP and how the pattern changed according to age . METHODS: Cross-sectional results from 1366 healthy Korean children and adolescents (10-19.9 years) from the Korean National Health and Nutrition Examination Survey were analyzed. We constructed age- and sex-specific reference data for sALP with a Hitachi Automatic Analyzer 7600 using Pureauto S ALP. We assessed its peak both in relation to age. RESULTS: Reference values for sALP according to age were constructed. Peak sALP levels were found at 12-13 years in boys (P < 0.001). Total sALP levels decreased to the adult level at the age of 17 in boys and 15 in girls, respectively. CONCLUSION: This study provides reference values for sALP by age for Korean children and adolescents. This normative data that includes upper and lower limits will provide a basis from which to better evaluate sALP levels, especially for bone disorders such as rickets and vitamin D deficiency. However, caution should be made in interpreting sALP levels because different buffers might lead to different values in the same serum.
Adolescent
;
Adult
;
Alkaline Phosphatase
;
Buffers
;
Child
;
Humans
;
Nutrition Surveys
;
Reference Values
;
Rickets
;
Sex Characteristics
;
Vitamin D Deficiency
7.The Transmission Performance Evaluation of Remote Healthcare Data over Secure Satellite Network.
Dong kyu LIM ; Sun K YOO ; Dong keun KIM ; Jung chae KIM ; Min hong CHOA
Journal of Korean Society of Medical Informatics 2008;14(4):439-449
OBJECTIVES: We have not only examined telemedicine scenario but also applied IPSec(AH, ESP) algorithms under VPN(Virtual Private Network) for performance evaluation of telemedicine system's security and transmission. METHODS: In this study, we applied IPSec(AH, ESP) algorithms under VPN(Virtual Private Network) protocol when transmit healthcare data through Satellite Network. At that time, we evaluated performance of telemedicine system through RTT(Round Trip Time), Jitter, Bandwidth that indicate to QoS(Quality Of Service). RESULTS: It is possible to transfer remote healthcare data over Satellite Network under provided image of 15 frame and bio-signal of 10 kbps and RTT(Round Trip Time) of 774.53ms, Jitter of 25.2ms. But applying IPsec(AH, ESP) under VPN(Virtual Private Network), it is frequently happened distortion of image data affected SHA-1 and 3DES algorithm. CONCLUSION: In this study, it is possible to use telemedicine system for Secure Satellite Network, but demand to be based QoS(Quality Of Service) limited. We expected that it is possible to use the designed system in the disaster area.
Delivery of Health Care
;
Disasters
;
Telemedicine
8.Acute Pulmonary Infarction Complicated with Thromboembolism as the First Manifestation of Hepatocellular Carcinoma.
Chae June LIM ; Ji Yun HONG ; Chung Hwan JUN ; Sung Kyu CHOI ; Sung Bum CHO
Journal of Liver Cancer 2017;17(2):163-167
Acute pulmonary infarction by tumoral thromboemboli is an extremely rare fatal complication as the first clinical manifestation of hepatocellular carcinoma (HCC) patient with tumoral thrombi in the inferior vena cava. The treatment method has not been established and shown to very poor prognosis despite of trying various modalities such as anticoagulation, radiotherapy and thromboembolectomy. Here, we describe a 74-year-old man who was diagnosed with HCC that presented as pulmonary thromboembolism and subsequent pulmonary infarction as the first manifestation.
Aged
;
Carcinoma, Hepatocellular*
;
Humans
;
Infarction
;
Methods
;
Prognosis
;
Pulmonary Embolism
;
Pulmonary Infarction*
;
Radiotherapy
;
Thromboembolism*
;
Vena Cava, Inferior
9.Performance Evaluation of LG AdvanSure HBV Real-Time QPCR Kit.
Jung Joo MOON ; Chae Seung LIM ; Chang Kyu LEE ; Heung Bum OH
Korean Journal of Blood Transfusion 2013;24(2):161-174
BACKGROUND: Accurate quantitative testing of HBV DNA is very important for choosing antiviral treatment targets and evaluating treatment response in chronic HBV patients. We evaluated the performance of LG AdvanSure HBV Real-Time QPCR kit (LG) utilizing real-time quantitative PCR. METHODS: The LG kit was conducted for 201 chronic hepatitis patients undergoing treatment at the Korea University Ansan hospital and 48 normal control volunteers. The precision, limit of detection, sensitivity, and specificity of LG Kit were evaluated. Correlation analysis was done with Abbott Real Time HBV kit (Abbott) and the Cobas Amplicor HBV Monitor kit (Cobas) and the concordances rate of the three methods were calculated. RESULTS: The LG assay showed linear range of detection from 10(2) to 10(6) and coefficient of variation (CV) was 1.10~0.52% at > or =1,000 IU/mL and 1.19% at 100 IU/mL. The coefficient of determination for precision analysis was 0.997. The limit of detection for detection of 95% of positive samples was 9.71 IU/mL (54.4 copies/mL). In 201 clinical samples, the log HBV DNA/ml showed good correlation between Roche vs Abott, Roche vs LG and Abott vs LG, respectively (n=105, 108, 133, r2=0.91, 0.89, 0.94, P<0.0001). The overall concordance rate of three methods were 79.1% (159/201), 82.1% (165/201), and 85.1% (171/201), respectively, showing no stastically significant difference (P>0.05). CONCLUSION: LG AdvanSure HBV Real-Time QPCR kit showed outstanding precision, linearity, limit of detection, good correlation with previous methods, and is a valuable tool in treatment monitoring of chronic HBV infections.
DNA
;
Hepatitis B
;
Hepatitis, Chronic
;
Humans
;
Korea
;
Limit of Detection
;
Organothiophosphorus Compounds
;
Sensitivity and Specificity
10.Autologous Frozen-thawed Blood Transfusion in the Bone Marrow Donors.
Chae Seung LIM ; Young Kee KIM ; Kap No LEE ; Byung Soo KIM ; Jun Seok KIM ; Kyu Seob HAN
Korean Journal of Blood Transfusion 1997;8(1):111-117
BACKGROUND: The cryopreservation of Red Blood Cells have been proved to have many advantages in western countries. However, in Korea, clinical application of frozen-thawed blood is still in its early stage. We tried autologous frozen-thawed blood transfusion and evaluated the effects and complications. METHODS: Nine units of whole blood were collected from the autologous (n=1) and allogeneic bone marrow donors (n=3) and made packed RBCs by a centrifugation method. We made frozen RBCs using high glycerol method and stored them in -80degrees C freezer for 1 month. Eight units of frozen RBCs were thawed and washed by Cobe spectra (Cobe, USA). Autologous transfusions were done to the patient and donors while the bone marrow collection procedures were in process for bone marrow transplantation and we carefully observed its effects and complications. RESULTS: The mean RBC recovery rate were 89.8% and the supernatant plasma hemoglobin, K+, LD, osmolality, and simulation test were satisfactory to the allowable limit. After transfusion, the hemoglobin value was significantly elevated being comparable to that of the fresh blood. A case showed mild hematuria related to this transfusion but soon it disappeared in a day. CONCLUSION: The autologous frozen-thawed blood transfusions were safe and as much effective as the fresh blood. It would be essential to have skillful techniques in post-thaw washing process.
Blood Transfusion*
;
Bone Marrow Transplantation
;
Bone Marrow*
;
Centrifugation
;
Cryopreservation
;
Erythrocytes
;
Glycerol
;
Hematuria
;
Humans
;
Korea
;
Osmolar Concentration
;
Plasma
;
Tissue Donors*