1.Syphilis Prevalence in Teagu Hope Village.
You Ho CHAE ; Sung Hwa KIM ; Sang Won KIM
Korean Journal of Dermatology 1986;24(2):249-253
Serologic tests for syphilis, including VDRL and TPHA tests, and Physical examination were carried out on 1, 605 subjects who lived in Taegu Hope Village, a social welfare center, from April, 198R to May, 1985. We prepared this study comparing with previous reports for healthy individuals and prostitutes. The results were as follows, The reactive rate of VDRL. qualitative test was 11. 6% in total, 10. 3%, in men and l3. 5%. in women. The reactive rates of VDRL. qualitative tests were highest in 7 th decade as 28, 7% and followed by 6 th decade as 16. 7% the decacile as 16. 0% 8 th decade as 14,3% 4th decade as 8. 8% and 3rd decade as 5. 9%, 3 In ]Hg sero-positive subjects, VDRL quantitative tests were done, and 35. 5% were reacted with 1: 8 or high and 29. 0% had one or more syphilitic lesions. 4 In 54 subjects who had one or more syphilitic lesions, 19 had chancres, 17 had alopecia syphilitica, 7 had rnaculopapular syphilid, 7 had condylomata lata. 3 had papular syphilid, and 1 had maculopapular syphilid and alopecia syphilitica. The biological false positive rate was 10. 1,4 in 138 VDRL reactive subjects, using 1;he TPHA test standard.
Alopecia
;
Chancre
;
Daegu
;
Female
;
Hope*
;
Humans
;
Male
;
Physical Examination
;
Prevalence*
;
Serologic Tests
;
Sex Workers
;
Social Welfare
;
Syphilis*
;
Syphilis, Cutaneous
2.Two Cases of Keratosis Palmaris et Plantaris.
You Ho CHAE ; Sung Hwa KIM ; Sang Won KIM
Korean Journal of Dermatology 1985;23(2):229-234
We described here-in a 36-year-old male patient (case 1) with a severe form of keratosis palmaris et plantaris(Thost-Unna type) which was diffuse hyperkeratosis with hyperhidrosis on the entire surface of the palms and soles. His son, 8-year- old boy, showed symmetrical distribution of hyperkeratotic patches on the inner sides of both great toes(case 2). Therefore, it was suggested this genodermatosis occured in two generations of a family. The biopsy taken from the right palm of case 1 showed features of epidermal hyperplasia with hyperkeratosis, hypergranulosis and acanthosis. We tried the oral Vit. A therapy(50,000 unit, daily) in case 2. The hyperkeratotic lesions became slightly improved in 4 months after therapy.
Adult
;
Biopsy
;
Family Characteristics
;
Humans
;
Hyperhidrosis
;
Hyperplasia
;
Keratoderma, Palmoplantar*
;
Keratosis*
;
Male
3.Undifferentiated Sarcoma of the Liver in an Adult: A case report.
Young Chae CHU ; Yong Hwa MOON ; In Sun KIM
Korean Journal of Pathology 1987;21(1):34-39
Undifferentiated sarcoma of the liver is a highly malignant neoplasm that occurs almost exclusively in children. We present a case of adult undifferentiated sarcoma in a 33-year-old man. The neoplasm was typically hypovascular on hepatic angiography and a globular, cystic and mucoid mass separated from the adjacent liver by a psedocapsule was removed from the left lobe of the liver. Necrosis and hemorrhage were found. Microscopically the neoplasm consisted of myxoid and cellular areas and the basic neoplastic cells were stellate cells showing variable degree of anaplasia and pleomorphism. Eosinophilic globules were PAS-positive and immunohistochemically negative for alpha-fetoprotein. Extramedullary hematopoiesis was present and normal-appearing bile ducts and hepatic cell cords were noted.
Child
;
Adult
;
Male
;
Female
;
Humans
4.A Case of Benign Hemangioendothelioma.
Eung Joo SUH ; You Ho CHAE ; Sung Hwa KIM ; Sang Won KIM
Korean Journal of Dermatology 1985;23(4):521-525
We report here-in a case of benign hemangioendothelioma occurring in a 2 day-old male neonate on central portion of lumbar area. The lesion was movable, and elevated firm nodule, measuring 1.5x2.0 cm in size. For the purpose of diagnosis and therapy, excisional biopsy was performed, which revealed typical histopathologic pictures in the deep dermis and subcutaneous area. The lesion showed no recurrence at follow-up check after 6 months.
Biopsy
;
Dermis
;
Diagnosis
;
Follow-Up Studies
;
Hemangioendothelioma*
;
Hemangioma
;
Humans
;
Infant, Newborn
;
Male
;
Recurrence
5.Morphological Changes of Hepatic Microcirculation in N-diethylnitrosamine Induced Cirrhotic Rat Liver.
Sang Han LEE ; Ji Hwa KIM ; Ik Su KIM ; Jong Min CHAE
Korean Journal of Pathology 1995;29(2):197-204
Morphological changes of hepatic microcirculation, especially in the peribiliary plexus, in cirrhotic livers of rats induced by repeated intraperitoneal injections of N-diethyinitrosamine (DEN) (100mg/kg/week) were studied by scanning electron microscopy. Control rats were treated with saline. The livers were perfused with saline and injected with methyl-methacrylated resin (Mercox CL-2B) through the thoracic aorta. Diffuse nodular changes mimicking human cirrhosis were seen in the livers six weeks after injections of DEN. The cirrhotic livers showed an increase of vascular channels composed mainly of venous branches around the regenerating nodules and increased arterioloportal anastonloses. Peribiliary plexi of the cirrhotic livers had more vessels than those of the controls. Many dilated veins and ramificating portal vein branches were also Present. Direct connections between peribiliary plexi and sinusoids or between peribiliary plexi and portal veins were increased in the cirrhotic liver. These results suggest that the peribiliary plexi in experimentally induced cirrhotic liver might play a role in a collateral circulation under a state of portal hypertension.
Humans
;
Rats
;
Animals
6.The PPARgamma Agonist Rosiglitazone Inhibits Glioma Cell Proliferation and Migration in vitro and Glioma Tumor Growth in vivo.
Chang Hwa CHOI ; Chae Hwa KWON ; Yong Keun KIM
Experimental Neurobiology 2009;18(2):112-122
Peroxisome proliferator-activated receptor-gamma (PPARgamma) has been implicated in the growth inhibition of a number of cancer cells. In the present study, we investigated the antitumor effect of the PPARgamma agonist rosiglitazone in U87MG human glioma cells. Rosiglitazone treatment in vitro reduced cell proliferation without induction of cell death in a dose- and time-dependent manner. Rosiglitazone decreased cell migration and mRNA level of MMP-9. Rosiglitazone treatment also induced marked changes in glioma cell morphology. Oral administration of rosiglitazone in animals with subcutaneous U87MG glioma cells reduced tumor volume. Subsequent tumor tissue analysis showed that rosiglitazone decreased the number of PCNA-positive staining cells and MMP-9 expression and induced apoptosis of tumor cells. These data suggest that rosiglitazone exerts antineoplastic effect in U87MG cells and may serve as potential therapeutic agent for malignant human gliomas.
Administration, Oral
;
Animals
;
Apoptosis
;
Cell Death
;
Cell Movement
;
Cell Proliferation
;
Glioma
;
Humans
;
Peroxisomes
;
PPAR gamma
;
RNA, Messenger
;
Thiazolidinediones
;
Tumor Burden
7.The comparative study for occlusal plane between articulated cast model and cephalogram in orthogantihic surgery patients.
Kyung Suk SEO ; Mi Hwa PARK ; Ju Hyun LEE ; Chul Hwan KIM ; Jong Moon CHAE
Journal of the Korean Association of Oral and Maxillofacial Surgeons 2003;29(4):239-244
The common errors in preoperative treatment plan for the orthognathic surgery can be occurred during cast impression, cast mounting procedure with face-bow transfer, surgical stent fabrication, and so on. One of the most common errors exists during mounting process of the model on the articulator. Accurate mounting of dental casts to articulator should be achieved by transferring the 3- dimensional spatial relationship of the maxillary arch to an articulator. A face-bow is used for transfer this relationship to articulator, usually by relating the face-bow to a plane of reference of maxillary cast. The purpose of this study is evaluation of the accuracy of face-bow transferring of maxillary model to the articulator. The maxillary casts of thirty patients for orthognathic surgery were mounted on articulator with an face-bow instrument. The relationship of occlusal plane angle to Frankfort horizontal plane relations were compared the cephalogram with the cast-mounted articulator. As a result of this study, the significant difference between the maxillary occlusal planes angle in the cephalogram and articulator were found . The results were followed,1. The mean occlusal plane angle in cast-mounted articulator was 13.5.(SD+/-5.4).2. The mean occlusal plane angle in cephalogram was 10.4.(SD+/-4.3).3. The mean difference of occlusal plane angle between cast-mounted articulator and cephalogram was 3.3.(SD+/-4.6).According to the result, we should suggest that the occlusal plane angle to Frankfort plane in cast-mounted articulator is more steeper than that of cephalogram.And then, maxillofacial surgeon should try to get a more predictable result by suggesting the proper correction method and mounting the cast accurately.
Dental Articulators
;
Dental Occlusion*
;
Humans
;
Orthognathic Surgery
;
Stents
8.A clinical study on inverted papilloma of the nose and paranasal sinuses.
Yang Gi MIN ; Sung Hwa HONG ; Hong Jong KIM ; Chae Seo RHEE
Korean Journal of Otolaryngology - Head and Neck Surgery 1991;34(5):962-967
No abstract available.
Nose*
;
Papilloma, Inverted*
;
Paranasal Sinuses*
9.Sparganosis in Subcutaneous Tissue of Thigh: A Case Report.
Soon Yong KWON ; Seung Koo RHEE ; Hwa Sung LEE ; Ki Won KIM ; Yoon CHAE
The Journal of the Korean Orthopaedic Association 1998;33(1):207-210
A case of rare subcutaneous sparganosis in thigh treated by surgical excision is reported. In this 49year-old male with a palpable mass on the anteromedial aspect of mid-thigh (5x7x5cm sized) which was misdiagnosed with a soft tissue tumor initially, a sparganosis was suspected by a plain x-rays, bone scan and his past history which he frequently had raw snakes, frogs and raw fishes before but confirmed by MRI and surgical excision. This represents tor warning to some Koreans who have frequently comsumed raw fishes, snakes or frogs etc., and to some doctors because it is easily confused with a soft tissue tumor.
Fishes
;
Humans
;
Magnetic Resonance Imaging
;
Male
;
Snakes
;
Sparganosis*
;
Subcutaneous Tissue*
;
Thigh*
10.A Case of Combined Ectopic Gestation with Cervical and Tubal Components.
Seung Hwa HONG ; Hye Eun KWON ; Sung Hoon KIM ; Hee Dong CHAE ; Chung Hoon KIM ; Byung Moon KANG
Korean Journal of Fertility and Sterility 2003;30(3):249-254
Ectopic pregnancy is a common medical problem that is difficult to diagnose and potentially may lead to significant mortality or morbidity. The incidence of ectopic pregnancy is definitely increasing due to the rise in pelvic inflammatory disease (PID), pelvic surgery, intrauterine device (IUD), and assisted reproductive technologies, such as in vitro fertilization and embryo transfer (IVF-ET). Combined ectopic gestations are much rare and their true incidence is unknown. Multiple ectopic gestations may occur in a variety of locations. The majority involve one or both fallopian tubes. We report a case of combined tubal and cervical pregnancies, and discuss their management.
Embryo Transfer
;
Fallopian Tubes
;
Female
;
Fertilization in Vitro
;
Incidence
;
Intrauterine Devices
;
Mortality
;
Pelvic Inflammatory Disease
;
Pregnancy*
;
Pregnancy, Ectopic
;
Reproductive Techniques, Assisted