1.A study on the bonding strength of resilient denture liners.
Sang Hoon LEE ; Chae Heon CHUNG
The Journal of Korean Academy of Prosthodontics 1992;30(3):411-436
No abstract available.
Denture Liners*
;
Dentures*
2.Diagnostic Efficiency of Lactate Dehydrogenase, Crreatine Kinase and Troponin T in Acute Myocardial Infarction.
Chae Hoon LEE ; Kyung Dong KIM ; Chung Sook KIM
Yeungnam University Journal of Medicine 1995;12(1):48-55
The present study was designed to evaluate the efficiency of total lactate dehydrogenase, total creatine kinase, LD1/LD2 ratio, CK-MB and newly developed troponin T in acute myocardial infarction. The level of troponin T was 0.010.02 pg/L in 34 healthy person, but the peak vaule of acute myocardial infarction ranged in 4.7-24.2 pg/L. Total lactate dehydrogenase was peaked in 1 to 3 days after chest pain and then progressively decreased, but LD1/LD2 ratio was persistently higher than 1.0 for 10 days in most patients. Total creatine kinase and CK-MB were peaked in 1-2 days, and normalized in 3-4 days, so they, were useful in early diagnosis of acute myocardial infarction, but not for the late stages of acute myocardiz l infarction. Troponin T is early elevated and persistently high level for more than 10 days. Comparing with total lactate dehydrogenase, total creatine kinase, LD1/LD2 ratio and CK-MB, troponin-T test improves the efficiency of serodiagnostic method for the detection of ischemic myocardial damage.
Chest Pain
;
Creatine Kinase
;
Early Diagnosis
;
Humans
;
Infarction
;
L-Lactate Dehydrogenase*
;
Lactic Acid*
;
Myocardial Infarction*
;
Phosphotransferases*
;
Troponin T*
;
Troponin*
3.Results of secondary antibiotics susceptibility test for gram negative bacilli resistant to primary susceptibility test in Yeungnam University Hospital.
Chung Sook KIM ; Kyung Dong KIM ; Chae Hoon LEE
Yeungnam University Journal of Medicine 1993;10(1):28-36
Major pathogenic Gramnegative organisms such as P. aeruginosa, Serratia species, E. coli, Enterobacter species which are isolated from the specimens in large medical centers are greatly resistant to the commonly used antibiotics. Gramnegative bacilli, which had been isolated in Yeungnam Uni rersity Hospital during the period from December 1992 to April 1993 and turned out to be resistant to the primary antibiotics susceptibility test for chloramphenicoi, ampicillin, eephaiothin,- geniamicitt, tetracyclin, amikin and tobramycin, were subjected to the secondary antibiotics susceptibility test for aztreonam, ceftazidime, ciprofloxacine, cefotaxime, cefamandole, piperacillin, ticarcillin and sulfamethoxazole trimethopime. Out of 315 tested organisms, 167 organisms (53%) were resistant to all secondary antibiotics in vitro. Antimicrobial activity of ceftazidime (37.1%), aztreonam (11. %), ciprofloxacine (7.9%) against Gram negative bacilli were slightly more active than other antibiotics tested, while cefamandole was not active to all the Gramnegative bacilli tested. According to the specimens, E. coli was the most frequently resistant organisms to the primary antibiotics from urine, A. baumanii, from respiratory system and wounds, and P. aeruginosa from various specimens. In summary, Gram negative bacilli resistant to the primarily applied antibiotics also were resistant to the secondary antibiotics. Rearrangement of the antibiotics disks for the antibiotic susceptibility test should be considered.
Amikacin
;
Ampicillin
;
Anti-Bacterial Agents*
;
Aztreonam
;
Cefamandole
;
Cefotaxime
;
Ceftazidime
;
Ciprofloxacin
;
Enterobacter
;
Piperacillin
;
Respiratory System
;
Serratia
;
Sulfamethoxazole
;
Ticarcillin
;
Tobramycin
;
Wounds and Injuries
4.Prevalence of HBV DNA in Packed Red Blood Cells.
Chae Hoon LEE ; Chung Sook KIM ; Dal Ho SONG
Yeungnam University Journal of Medicine 1995;12(2):339-346
Assays for HBsAg, HBV DNA, anti-HBc and anti-HBs of 285 units of packed red blood cells supplied by Taegu Red Cross Blood Center were performed to evaluate the correlation between the prevalence of HBV DNA and the serologic markers for hepatitis B virus. None of 285 plasma samples was positive for HBsAg, however, HBV DNA were detected by polymerase chain reaction in 2 samples which both presented only with anti-HBc positivity.. Of 204 samples tested for anti-HBs, 96 samples(47.1%) were positive and among 216 samples tested for anti-HBc, 80 samples(37.0%) were positive. Of 193 samples tested for both anti-HBs and anti-HBc, 80(41.1%) were all negative and 48(24.9%) were positive on both tests. Those samples which showed positivity only to anti-HBc were 25(13.0%). Considering the above results, transfusion-transmitted hepatitis B virus infection could be prevented by discarding anti-HBc positive blood, however, that may bring insufficient supply of donor bloods in the country like Korea where the prevalence of anti-HBc is high. Anti-HBc positive blood unequivocally positive for anti-HBs should be considered noninfectious for HBV and should be allowed to be transfused. It would reduce the amount of discarding donor blood as the routine blood donor screening tests presently used at Korea Red Cross Blood Center supplemented by anti-HBs and anti-HBc testing.
Blood Donors
;
Daegu
;
DNA*
;
Erythrocytes*
;
Hepatitis B Surface Antigens
;
Hepatitis B virus
;
Humans
;
Korea
;
Mass Screening
;
Plasma
;
Polymerase Chain Reaction
;
Prevalence*
;
Red Cross
;
Tissue Donors
5.Evaluation of Automated ESR Measuring system, SEDIsystem(TM).
Jung Ee LEE ; Kyung Dong KIM ; Chae Hoon LEE ; Chung Sook KIM
Yeungnam University Journal of Medicine 1996;13(1):110-115
The ESR is one of the oldest laboratory test still in use. Although it lacks specificity in diagnosis, it can be effective for monitoring disease activity and following-up. The Westergren method is used for reference method, however coefficient of variation has been described 0.8% to 22.9% according to the literature. Since the ESR was invented in 1921, measurement technique has developed and automated measurement is introduced. We analyzed one hundred forty-three patient samples using SEDIsystem' automated ESR measuring system and compared with modified Westergren and Wintrobe methods. Comparison between SEDIsystem' and modified Westergren for ESR measurement yields the following regression equation; y = 0.863x - 1.69 (r=0.830), SEDIsystem'M and Wintrobe y'= 1.14x - 14.7 (r=0.789), rcspectively. We repeated measurement to evaluate reliability, results are not significant in statistically. In conclusion, SEDIsysten' automated ESR measurement correlated with modified Westergren and Wintro" ; methods, reveal reliable results after 4 hours and can report rapidly for large samples. Thus, these results indicate that SEDIsystenT"' automated ESR measurement may be useful tool for clinical practice.
Diagnosis
;
Humans
;
Sensitivity and Specificity
6.Bacterial growth in artificially contaminated packed red cells following room temperature exposure.
Bo Chan JEONG ; Chae Hoon LEE ; Kyung Dong KIM ; Chung Sook KIM ; Dal Hyo SONG
Korean Journal of Blood Transfusion 1993;4(1):89-95
No abstract available.
7.Comparison of Clinical Outcomes according to the Catheters undergoing Intrauterine Insemination.
Hee Dong CHAE ; Eun Hee KANG ; Chung Hoon KIM ; Byung Moon KANG ; Yoon Seok CHANG
Korean Journal of Obstetrics and Gynecology 2000;43(2):254-259
OBJECTIVE: To compare the clinical outcomes of intrauterine insemination (IUI) according to the catheter used. MATERIALS AND METHOD: From March 1998 to September 1998, total 95 infertile patients were included in this study. Patients were randomly allocated to TomCat group (n = 39) and Mackler group (n = 56) according to the catheter for insemination. The controlled ovarian hyperstimulation (COH) using luteal long protocol of gonadotropin releasing hormone agonist (GnRH-a) was used in all patients. Statistical analysis was performed using Student's t-test, Fisher's exact test, and x2 test as appropriate. Statistical significance was defined as p < 0.05. RESULTS: The total dose and duration of exogeneous gonadotropin required were similar between the two groups. There were also no significant differences in serum estradiol (E2) level, endometrial thickness and texture on the day of hCG administration between the two groups. However, the percentage of uterine souding due to failure of initial approach was significantly higher in TomCat group compared to Mackler group (23.1% vs. 0%, p < 0.01). The percentage of bleeding after IUI in TomCat group seemed to be higher than that in Mackler group (15.4% vs. 3.6%, p = 0.06), although there was no statistically significant difference between the two groups. There was also no significant difference in the clinical pregnancy rate per patient between the two groups. CONCLUSION: These results suggested that using Mackler catheter might be effective for IUI, especially for the patients with cervical factor infertility.
Catheters*
;
Estradiol
;
Gonadotropin-Releasing Hormone
;
Gonadotropins
;
Hemorrhage
;
Humans
;
Infertility
;
Insemination*
;
Pregnancy Rate
8.Comparison study of AAS and ISE method in the lithium analysis of serum and urine.
Soo In LEE ; Chae Hoon LEE ; Kyung Dong KIM ; Chung Sook KIM
Yeungnam University Journal of Medicine 1993;10(2):409-416
In the method for lithium (Li) analysis, flame emission photometry and atomic absorption spectrophotometry (AAS) have been used most frequently. In addition, lithium can be analyzed by ion-selective electrode (ISE) or fluorscence polarization immunoassay. We evaluated the comparison between AAS method based on the principle of absorption of light at 670.8 nm by Li and ISE method based on the principle of voliage difference generated by Li in contact with lithium ionophore. We compared with those obtained by AAS (AA/AE Spectrophotometer 551, Instrumentation Laboratory Co.) and ISE (SYNCHRON EL-ISE, Beckman Co.) in the serum and urine of 6 pati,,:nts- and evaluated time-related changes of serum lithium concentration after dosing in both methods. The results are summarized-as follows: 1. In within-run precision study for lithium concentration, coefficient variations (CVs, %) ranged from 1.34 to 2.17 for AAS and from 0.34 to 0.85 for ISE method. In between-run precision study for lithium concentration, CVs ranged from 1.23 to 1.72 for AAS and from 0.61 to 1.38 for ISE method. 2. The correlation study between AAS and ISE method resulted in Y= 0.946X+ 0.137 (N = 32, r= 0. 933, X= AAS, Y= ISE) for serum lithium and Y= 1. 092X+ 0. 977 (N= 28, r= 0.943, X= AAS, Y= ISE) for urine lithium. 3. Time-related changes of serum lithium concentration in both AAS and ISE method resulted in peak serum levels about 2 hours after dosing and then rapidly decreased after the peak serum level and finally arrived at nearly initial levels about 9 hours after dosing. 4. The reference range of serum lithium was found as undetectable level for both AAS and ISE method and the reference range of urine lithium to the urine creatinine was 0 0.00014 mmol/mg(mean 0.00002 mmol/mg) for AAS method.
Absorption
;
Creatinine
;
Immunoassay
;
Ion-Selective Electrodes
;
Lithium*
;
Photometry
;
Reference Values
;
Spectrophotometry, Atomic
;
Statistics as Topic
9.Serum Angiotensin-Coverting Enzyme Levels in Coal Worker's Pneumoconiosis.
Kyung Dong KIM ; Myung Sook CHOI ; Chae Hoon LEE ; Chung Sook KIM ; Eun Kyung BAE
Yeungnam University Journal of Medicine 1989;6(1):109-119
We measured fasting Serum Angiotensin-Converting Enzyme (SACE) in 100 healthy controls and 75 coal worker's pneumoconiosis (CWP) patients by a commercial kits (ACEcolor®, Fujirio Inc., Japan) and evaluated this manual method. The linear range extends to an activity of 80U/L. Precision on a commercial control serum (ACE control-N®, Sigma Co.) with a mean value of 9.47U/L yielded a within-run and between-run CVs are 5.6% (N=15) and 6.9% (N=14) respectively. Save in 75 CWP was 20.3±5.7U/L (mean±s.d.); higher than in healthy controls (13.4±3.9U/L, P<0.01). No correlation was found between SACE, sex, and age. The results suggest that the measurement for SACE and follow-up SACE in coal workers may be a useful diagnostic tools for CWP.
Anthracosis*
;
Coal*
;
Fasting
;
Follow-Up Studies
;
Humans
;
Methods
10.Diagnostic Significance of Cold Agglutinin and Antimycoplasma Antibody for Mycoplasma pneumoniae Infection.
Chung Sook KIM ; Chae Hoon LEE ; Chang Ho JEON ; Eun Kyung BAE ; Seak il HONG
Yeungnam University Journal of Medicine 1987;4(1):97-103
A study to evaluate the diagnostic significance of M. pneumoniae Infection by measurements of cold agglutinin and antimycoplasma antibody titers is performed with 191 pediatric patients who have visited Yeungnam University Hospital during the period through January to July, 1987. Forty eight of 191 cases made follow up tests feasible. The results obtained are as follows: 1. It is necessary to perform routine combined measurements of cold agglutinin and antimycoplasma antibody titers for the all pediatric pneumonia caser since a large proportion of pneumonia in children is caused by M. pneumonia. 2. For the diagnosis of M. pneumoniae Infection, measurements of cold agglutinin titer alone seems to be less significant than to check both cold agglutinin and antimycoplasma antibody titers. 3. The measurement of antimycoplasma antibody titer appeared to be more specific than cold agglutinin test in the diagnosis of M. pneumoniae Infection. 4. The present study urges the necessity of follow up study of cold agglutinin and antimycoplasma antibody titer for those who initially presented with normal titers in both tests, but are clinically suspected for M. pneumoniae Infection.
Child
;
Diagnosis
;
Follow-Up Studies
;
Humans
;
Mycoplasma pneumoniae*
;
Mycoplasma*
;
Pneumonia
;
Pneumonia, Mycoplasma*