No abstract available.
Cerebral Palsy* ; Early Diagnosis* ; Neurologic Examination*

OBJECTIVETo study the clinical features of non-epileptic seizures associated with cerebral palsy (CP) in children.

METHODSA total of 1 198 children with CP (age: 9 months to 6 years) were enrolled. The children with paroxysmal events were monitored by 24 hrs video-EEG (VEEG) to make sure the seizures were epileptic or non-epileptic. The symptoms, age, CP types and EEG features were observed in children with non-epileptic CP.

RESULTSFive hundred and seventy-eight children (48.24%) presented paroxysmal events. The seizures were epileptic in 231 children (19.28%) and non-epileptic in 322 cases (26.88%). In the 322 cases of non-epileptic CP, the paroxysmal events were of various kinds, including non-epileptic seizure tonic, seizure shake head, shrug shoulder or head hypsokinesis, cry or scream, panic attacks, sleep myoclonic and stereotyped movement. One hundred and fifty-eight (49.1%) out of the 322 children demonstrated nonspecific EEG abnormalities. One hundred and eleven children (34.5%) were misdiagnosed as epilepsy in primary hospitals. The CP children less than one year old showed higher frequency of non-epileptic seizures than the age groups over 1 year and 3 to 6 years. The frequency of non-epileptic seizures was the highest in children with spastic CP (168 cases, 52.2%), followed by dyskinetic CP (69 cases, 21.4%) and mixed type CP (65 cases, 20.2%).

CONCLUSIONSThe paroxysmal events in children with CP partially are non-epileptic seizures and it is important to differentiate non-epileptic from epileptic seizures. The frequencies of non-epileptic seizures may be associated with a child's age and CP type.

Cerebral Palsy ; Diagnostic Errors ; Electroencephalography ; Epilepsy ; diagnosis ; Humans ; Seizures ; diagnosis

The aims of this paper were to define (1) criteria of cerebral palsy; (2) classification of cerebral palsy; (3) etiology, neuroimaging, and epidemiology of cerebral palsy; (4) different kinds of treatments of cerebral palsy. Data were drawn from an international survey of PUBMED (1994-2014) and CNKI (1994-2014). An expert panel used a consensus building technique. The10-point Jadad scale was used to assess the quality of the trials based on the following items, including allocation sequence generation, randomization concealment, methods of blinding, and descriptions of withdrawals and dropouts. Our clinical experience was also summarized. Below is a summary. (1) Further work is warranted to reach agreement for the classification of cerebral palsy. (2) A worldwide prevalence of 1.5-4.0 per 1 000 live births, with an average lifetime cost of 1 million dollars per person in the United States, while it is 1.8-6.0 per 1000 live births in China. (3) Comparison of clinical efficacy of different treatments. In this review, the current advances in different kind of treatments of brain injury are discussed with specific relevance to cerebral palsy.
Cerebral Palsy ; classification ; diagnosis ; therapy ; China ; Humans ; Prevalence ; United States

Cerebral Palsy ; diagnosis ; etiology ; therapy ; Humans ; Magnetic Resonance Imaging ; Prognosis

OBJECTIVE: To review the medical utilization in children with cerebral palsy according to age and discern particularities METHODS: From January 2007 to December 2007, 10,659 children and adolescents between 1 and 18 years of age who had filed national insurance claims for a diagnosis of cerebral palsy were selected. Age was chosen as an independent variable, and the population was categorized into specific age groups to verify any differences in medical service utilization. Admission duration to rehabilitation, number of visits to rehabilitation outpatient clinics, numbers of admission dates and outpatient clinic visits for general medical services, number of rehabilitation utilizations, and type of rehabilitations treatment were selected as dependent variables. One-way ANOVA was used for statistical evaluation, and analysis was done with SAS software. RESULTS: In general medical use, adolescences diagnosed with cerebral palsy had the highest mean admission duration (p<0.001). The mean visit day to outpatient clinics for general medical services was highest for infants (p<0.001). In rehabilitation treatment, infants diagnosed with cerebral palsy had the highest mean admission duration (p<0.001). The mean visit day to outpatient clinics for rehabilitation treatment was highest for infants (p<0.001). CONCLUSION: Significant differences in use of general and rehabilitation medical services among pediatric age groups with cerebral palsy were evident. This implies that particular attention is necessary when setting up a national medical care policy for patient with cerebral palsy.
Adolescent ; Ambulatory Care Facilities ; Cerebral Palsy* ; Child* ; Diagnosis ; Humans ; Infant ; Insurance ; Rehabilitation* ; Sensitivity and Specificity*

Despite improvement in perinatal practice during the past several decades, the incidence of cerebral palsy has remained essentially unchanged. The cause of cerebral palsy is thought to be multifactorial, including prematurity, inflammation, genetic cause and environmental factors. Although evidences suggest that 70-80% of cerebral palsy is due to prenatal factors and birth asphyxia plays a relatively minor role (<10%), development of cerebral palsy is frequently attributed to the obstetric misstep. Therefore, it is of critical importance to keeping in touch with recent trend and advances regarding cerebral palsy. In this background, this review was mainly focused on the articles published from Jan 2006 to June 2007, excluding the orthopedic and rehabilitational aspects. The subjects are arbitrary divided into the following four categories; 1) recent epidemiologic studies of cerebral palsy, 2) recent evidences of antenatal risk factors, 3) cerebral palsy and placental pathology, 4) role of MRI in diagnosis of cerebral palsy.
Asphyxia ; Cerebral Palsy* ; Diagnosis ; Epidemiology ; Incidence ; Inflammation ; Magnetic Resonance Imaging ; Orthopedics ; Parturition ; Pathology ; Risk Factors

OBJECTIVETo evaluate the prospective validity and predictive value of cerebral palsy during infancy, using 'Infant Motor Malfunction Profile'.

METHODSItems of motor milestone in the profile was used as the first step to screen cerebral palsy on 8137 infants who were screened at 3, 6, 9, 12 months of age. The positive cases who had one of 7 developmental abnormal motor milestone items were examined using the items of primitive reflexes or postural reaction as the secondary step of cerebral palsy screening. The cases who had at least one abnormal item of primitive reflex or postural reaction received neurological examination by doctors to diagnose cerebral palsy.

RESULTSAccording to our data, sensitivity, specificity, positive prospective value, positive and negative likelihood ratio of the profile in screening cerebral during infancy were 94.1%, 99.8%, 48.5%, 449.6 and 0.06, respectively.

CONCLUSIONThe profile seemed to be an acceptable instrument for early identification of cerebral palsy.

Cerebral Palsy ; diagnosis ; Female ; Humans ; Infant ; Male ; Mass Screening ; methods ; Prospective Studies ; Sensitivity and Specificity

Cerebral Palsy ; diagnosis ; etiology ; physiopathology ; Hearing Disorders ; etiology ; Humans ; Interleukin-6 ; analysis ; Prognosis ; Research Report

Under the guidance and support of national policies in recent years, the community medical system has been developed rapidly, among which primary child healthcare is carried out routinely in community hospitals, greatly alleviating the pressure of specialized pediatric hospitals and departments of pediatrics in secondary and tertiary general hospitals. However, due to the lack of professional training for primary child healthcare personnel in community medical institutions, early symptoms of children with cerebral palsy cannot be identified and so children with cerebral palsy are often unable to receive early diagnosis and intervention, which may affect their prognosis. An article about international expert consensus and recommendations on early identification and referral of cerebral palsy in community medical institutions was published in
Cerebral Palsy/diagnosis* ; Child ; China ; Early Intervention, Educational ; Family ; Humans ; Referral and Consultation

OBJECTIVE: To investigation the further inquiry the reasons of cerebral palsy child's hearing lose, and giving the hearing lose children of cerebral palsy overall medical treatments in time, this paper has given the academic comprehensive analysis of the reasons of this synthetic symptom above. METHOD: By the means of the medical checks of ABR, OAE and acoustic immittance measurements, we have investigated the reasons, and analyzed the types of all cerebral palsy children in our hospital from January to December in 2005. RESULT: The result of medical checks in 484 cerebral palsy children showed that there were 160 abnormal cases (33.06%), and we marked OAE medical check to the 92 abnormal cerebral palsy children, there are 36.90% passing rates. among which the passing rate of slight hearing lose (72.00%) is obviously higher than that of the serious hearing lose (4.20%). CONCLUSION The symptoms of serious suffocation, premature delivery, and jaundice are not only the main factors given rise to the cerebral palsy, but also are the main reasons led to cerebral palsy child's hearing lose.
Cerebral Palsy ; physiopathology ; Child ; Child, Preschool ; Female ; Hearing Loss ; diagnosis ; etiology ; Humans ; Infant ; Male