1.Surgical Treatment of Hemangioblastoma in the Pituitary Stalk: An Extremely Rare Case.
Jaejoon LIM ; Sunghyun NOH ; Kyung Gi CHO
Yonsei Medical Journal 2016;57(2):518-522
Hemangioblastoma (HBL) in the pituitary stalk is extremely rare. Only 16 such cases have been reported in the past and 5 cases have been treated with surgical procedure. Here, we report surgical case of HBL in the pituitary stalk diagnosed in a 34-year-old woman. The patient underwent a gross-total resection via the modified lateral supra-orbital approach. No recurrence was observed in two years after surgery. To our knowledge, this is the 17th case of HBL in the pituitary stalk and the 6th surgical case. If the tumor is symptomatic and the volume is over 5 cubic centimeters as in our case, we recommend that the surgical resection of the HBL in the pituitary stalk is a more safe and reasonable than radiotherapy.
Adult
;
Cerebellar Neoplasms/pathology/*surgery
;
Female
;
Hemangioblastoma/pathology/*surgery
;
Humans
;
Pituitary Gland/*pathology
;
Treatment Outcome
2.Dysplastic gangliocytoma of cerebellum (Lhermitte-Duclos disease): report of a case.
Chinese Journal of Pathology 2005;34(10):694-695
Adolescent
;
Cerebellar Cortex
;
metabolism
;
pathology
;
Cerebellar Neoplasms
;
metabolism
;
pathology
;
surgery
;
Female
;
Follow-Up Studies
;
Ganglioneuroma
;
metabolism
;
pathology
;
surgery
;
Humans
;
Neurofilament Proteins
;
metabolism
;
Synaptophysin
;
metabolism
4.Medulloblastoma with extensive nodularities: report of a case.
Qiu-ping GUI ; Xin SONG ; Huai-yu TONG
Chinese Journal of Pathology 2007;36(9):644-645
Cerebellar Neoplasms
;
diagnosis
;
pathology
;
radiotherapy
;
surgery
;
Follow-Up Studies
;
Humans
;
Infant
;
Magnetic Resonance Imaging
;
Male
;
Medulloblastoma
;
diagnosis
;
pathology
;
radiotherapy
;
surgery
5.A Case of Medullomyoblastoma of Cerebellopontine Angle Mimicking Acoustic Neuroma.
Sang Yoo PARK ; Jin Hyung KIM ; Ki Taek KIM ; Yoo Jung KIM ; Tae Hwan KIM ; Keum HWANG ; Ki Jun SUNG ; Kwang Hwa PARK
Yonsei Medical Journal 2004;45(4):719-722
Medulloblastoma is a common malignant central nervous system neoplasm found mainly in children. One the contrary, medulloblastoma of the cerebellopontine angle, the location of the tumor is very unusual. This is the the first case of the medullomyoblastoma, a rare form of medulloblastoma, occurring in the cerebellopontine angle. A 15-year-old boy experienced a sudden hearing loss in the left ear. Conservative medical treatment failed, and temporal MR imaging revealed a heterogeneously enhancing mass at the left cerebellopontine angle cistern and in the internal auditory canal; therefore, the lesion was regarded as a typical acoustic neuroma. Few days before surgery, an ipsilateral facial palsy developed, and a follow-up MR imaging showed a rapid growth of the previous lesion. The extended translabyrinthine approach permitted surgical removal. And under pathological diagnosis of malignancy, radiation therapy and series of chemotherapy was performed.
Adolescent
;
Cerebellar Neoplasms/*pathology/surgery
;
Cerebellopontine Angle/*pathology
;
Diagnosis, Differential
;
Humans
;
Magnetic Resonance Imaging
;
Male
;
Medulloblastoma/*pathology/surgery
;
Neuroma, Acoustic/*pathology
6.The report and pathologic analysis of 2 cases of Von Hippel-Lindau disease in twins of brother.
Xiao-Mei LIU ; Yin-Ping WANG ; Li-Ping ZHAN ; Jing QIAO ; Jun-Ge ZHANG ; Shou-Shui XU
Chinese Journal of Pathology 2005;34(11):760-761
Adult
;
Carcinoma, Renal Cell
;
pathology
;
surgery
;
Cerebellar Neoplasms
;
pathology
;
surgery
;
Cystadenoma, Papillary
;
pathology
;
surgery
;
Diseases in Twins
;
pathology
;
surgery
;
Epididymis
;
pathology
;
surgery
;
Genital Neoplasms, Male
;
pathology
;
surgery
;
Hemangioblastoma
;
pathology
;
surgery
;
Humans
;
Kidney Neoplasms
;
pathology
;
surgery
;
Male
;
von Hippel-Lindau Disease
;
pathology
;
surgery
7.Gliosarcoma of the Cerebellar Hemisphere: a Case Report and Review of the Literature.
Sung Kyoung MOON ; Eui Jong KIM ; Woo Suk CHOI ; Chang Woo RYU ; Bong Jin PARK ; Juhie LEE
Korean Journal of Radiology 2010;11(5):566-570
Gliosarcoma is a rare central nervous system tumor usually located in the supratentorial area. Here we report a rare case of a gliosarcoma that developed in the cerebellar hemisphere in a 70-year-old woman. Computed tomography (CT) and magnetic resonance imaging (MRI) of the brain revealed an infratentorial mass of which radiological features were similar to those of glioblastoma. The tumor was diagnosed by pathology as a gliosarcoma. Though rare, gliosarcoma should be considered in the differential diagnosis of infratentorial tumors with radiological features of glioblastoma or metastasis in elderly patients.
Aged
;
Cerebellar Neoplasms/*diagnosis/pathology/surgery
;
Contrast Media/diagnostic use
;
Female
;
Gliosarcoma/*diagnosis/pathology/surgery
;
Humans
;
Magnetic Resonance Imaging
;
Tomography, X-Ray Computed
8.Disseminated Hemangioblastomatosis of the Central Nervous System without von Hippel-Lindau Disease: A Case Report.
Hong Rae KIM ; Yeon Lim SUH ; Jong Won KIM ; Jung Il LEE
Journal of Korean Medical Science 2009;24(4):755-759
We report a very rare case of hemangioblastomatosis that developed after surgical removal of a solitary cerebellar hemangioblastoma (HB). A 51-yr-old man presented with back pain 10 yr after undergoing surgery for cerebellar HB. Magnetic resonance imaging showed numerous mass lesions along the entire neuraxis accompanied by prominent leptomeningeal enhancement. Genomic DNA analysis showed no mutation in the von Hippel-Lindau (VHL) genes. A surgical specimen obtained from a lesion in the cauda equina showed pathological findings identical to those of the cerebellar HB that had been resected 10 yr earlier. External beam radiation therapy and radiosurgery were subsequently performed; however, the patient succumbed one year after receiving the diagnosis of hemangioblastomatosis. The reduction of tumor cell spillage during surgery and regular long-term follow-up are recommended for patients with HBs.
Central Nervous System Neoplasms/*diagnosis/pathology/surgery
;
Cerebellar Neoplasms/pathology/radiotherapy/surgery
;
Hemangioblastoma/*diagnosis/pathology/surgery
;
Humans
;
Magnetic Resonance Imaging
;
Male
;
Middle Aged
;
Recurrence
;
von Hippel-Lindau Disease/genetics
9.Malignant meningioma of the cerebellopontine angle in a 2-year-old girl: a case report and literature review.
Ming-Chao FAN ; Xin ZHANG ; Qiao-Ling WANG ; Lei CHENG ; Cai-Yun DAI ; Dan YU ; Peng SUN
Chinese Journal of Cancer 2013;32(7):415-417
Meningioma is a common intracranial tumor in adults. Pediatric cases account for approximately 1.5% of all intracranial meningiomas, and very few cases show malignant histological features. Primary pediatric malignant meningioma in the cerebellopontine angle is extremely uncommon. Herein, we report a 2-year-old girl with malignant meningioma in the cerebellopontine angle. The clinical features, diagnosis, and treatment protocol are discussed.
Cerebellar Neoplasms
;
diagnostic imaging
;
metabolism
;
pathology
;
surgery
;
Cerebellopontine Angle
;
Child, Preschool
;
Female
;
Follow-Up Studies
;
Humans
;
Meningeal Neoplasms
;
diagnostic imaging
;
metabolism
;
pathology
;
surgery
;
Meningioma
;
diagnostic imaging
;
metabolism
;
pathology
;
surgery
;
Mucin-1
;
metabolism
;
Radiography
;
S100 Proteins
;
metabolism
;
Vimentin
;
metabolism
10.Acute Comitant Esotropia in a Child With a Cerebellar Tumor.
Jong Min LEE ; Sin Hoo KIM ; Jeong Il LEE ; Ji Yong RYOU ; Sook Young KIM
Korean Journal of Ophthalmology 2009;23(3):228-231
We report a case of acute comitant esotropia in a child with a cerebellar tumor. A 3-year-old boy was referred for management of a 9 month history of acute acquired comitant esotropia. On first presentation, the patient's angle of esodeviation was 50 prism-diopters (PD) at distance and near fixation without any lateral incomitance. The cycloplegic refraction revealed +0.75 diopters in both eyes. Very mild bilateral papilledema was found on the fundus examination, but the neurological examination did not reveal any other pathological findings. Brain MRI showed a 5 cm mass located in the midline of the cerebellum as well as hydrocephalus. The mass was completely excised and histological examination confirmed the diagnosis of pilocytic astrocytoma. Despite neurosurgery, the patient's strabismus remained unresolved. One year after neurosurgery, both medial rectus muscles were surgically recessed by 6 mm, resulting in esotropia of 8PD at distant and near fixation without restoration of bifoveal fusion at follow-up 2 years after the eye muscle surgery. Therefore, acute onset comitant esotropia in a child can be the first sign of a cerebellar tumor, even without any other neurological signs and symptoms.
Acute Disease
;
Astrocytoma/*complications/surgery
;
Brain/pathology
;
Cerebellar Neoplasms/*complications/diagnosis/surgery
;
Child, Preschool
;
Esotropia/*etiology/pathology/physiopathology/surgery
;
Humans
;
Magnetic Resonance Imaging
;
Male
;
Neurosurgical Procedures
;
Oculomotor Muscles/surgery
;
Refraction, Ocular
;
Time Factors