1.Ginseng may modify the progression of degenerative cerebellar ataxia: A report of two case
Min Jung Oh ; Min-Wook Kim ; Manho Kim
Neurology Asia 2015;20(3):313-318
Cerebellar degeneration is a group of diseases that manifests as progressive ataxia, that finally led to
death without specific treatment. We report here two patients with cerebellar degeneration, who had
shown an improvement and less progressive course, which is associated with panax ginseng intake.
Patient 1 was a 60-year-old woman with multisystem atrophy (MSA) type C with 5 year history of
ginseng ingestion. Patient 2 was a 54-year-old woman with spinocerebellar ataxia (SCA) type 6,
who had a history of ginseng intake for 30 months. Both the patients showed atrophic change in the
cerebellum by brain magnetic resonance imaging. Cerebellar functions had been semi-quantified by
International Cooperative Ataxia Rating Scale (ICARS) and monitored before and after the ginseng
ingestion every 6 to 12 months. In Patient 1 with MSA type C, ICARS had improved from 21 to 17.5
± 1.8 in the following 5 years. In Patient 2 with SCA, ICARS also showed an improvement from
22 to 6.0 ± 1.0 over 30 months. However, when she stopped taking ginseng, it progressed up to 13
points in two years. These observations provide a potential disease-modifying effect of ginseng on
patients with cerebellar degeneration.
Cerebellar Ataxia
;
Cerebellar Diseases
2.A Case of Progressive Ataxia and Palatal Tremor.
Suk Woo YONG ; Phil Hyu LEE ; Seung Hyun YEO ; Jae Hyuk LEE
Journal of the Korean Neurological Association 2005;23(4):568-570
Progressive ataxia and palatal tremor (PAPT) is a subgroup of symptomatic palatal tremors which is characterized by palatal tremor and idiopathic progressive cerebellar ataxia. Here, we report a 59 year-old-male who presented with a 5 months history of progressive cerebellar ataxia, and was discovered to have both a symptomatic palatal tremor and torsional nystagmus. Various studies searching for the cause of the ataxia and the palatal tremor all came out negative, thus defining this patient as a PAPT.
Ataxia*
;
Cerebellar Ataxia
;
Humans
;
Tremor*
3.Reversible Cerebellar Ataxia Secondary to Carcinoid Tumor.
Venugopalan Y VISHNU ; Santosh CHIKKODI ; Harkant SINGH ; Nandita KAKKAR ; Manish MODI ; Manoj Kumar GOYAL ; Vivek LAL
Journal of Clinical Neurology 2016;12(4):505-506
No abstract available.
Carcinoid Tumor*
;
Cerebellar Ataxia*
4.Spinocerebellar Ataxia Type 8 Presenting as Ataxia without Definite Cerebellar Atrophy.
Yong Jun EO ; Sung Keun KIM ; Sung Hun KIM ; Jae Won JANG
Journal of the Korean Neurological Association 2017;35(1):55-57
No abstract available.
Ataxia*
;
Atrophy*
;
Cerebellar Ataxia
;
Spinocerebellar Ataxias*
5.Cerebellar type Ataxia in Middle Cerebral Artery Territory Infarction.
Sang Won SEO ; Ji Hoe HEO ; Ji Hyun KIM ; Seung Min KIM
Journal of the Korean Neurological Association 2001;19(6):671-673
No abstract available.
Ataxia*
;
Cerebellar Ataxia
;
Infarction*
;
Middle Cerebral Artery*
6.A Cses of Hereditary Cerebellar Ataxia in Brothers.
In Bok LEE ; Jon Gerl LEE ; Chang Soo RA
Journal of the Korean Pediatric Society 1979;22(3):239-244
We experienced two suspected cases of hereditary cerebellar ataxia of ten years and right years aged boys who brothers. The patients manifested progressive wide base ataxic gait, incordination, intention tremor, impaired balance and dysarthria. A bries review of related literature is also presented.
Cerebellar Ataxia*
;
Dysarthria
;
Gait
;
Humans
;
Siblings*
;
Tremor
7.Antibodies to the Antiganglioside GD1b in a Guillain-Barre Syndrome Patient with Bilateral Cerebellar Lesions.
Sang Gon LEE ; Jung Geun OH ; Hyung Kyun IM ; Hojin CHOI ; Seong Ho KOH ; Kyu Yong LEE ; Young Joo LEE
Journal of the Korean Neurological Association 2014;32(4):345-347
No abstract available.
Antibodies*
;
Cerebellar Ataxia
;
Guillain-Barre Syndrome*
;
Humans
8.A Case of Familial Spinocerebellar Ataxia Type 8.
Sang Hyeon LEE ; Chang Seok KI ; Hyung In CHO ; Pyung Won LEE ; Jong Won KIM ; Won Yong LEE
Journal of the Korean Neurological Association 2004;22(6):659-662
Spinocerebellar ataxia type 8 (SCA8), originally described in a family characterized by pure cerebellar ataxia, is caused by the expansion of combined CTA/CTG repeats on chromosome 13q21. We experienced a 26-year-old man who presented with a 10-years history of slowly progressive gait ataxia, dysarthria and blepharospasm. We performed genetic studies for SCA1, 2, 3, 6, 7 and 8, and detected CTA/CTG repeat expansion in the SCA8 gene. We now report the first Korean familial case of SCA8 confirmed by genetic study.
Adult
;
Blepharospasm
;
Cerebellar Ataxia
;
Dysarthria
;
Gait Ataxia
;
Humans
;
Spinocerebellar Ataxias*
9.A Case of Early Onset Cerebellar Ataxia with Retained Tendon Reflexes.
Jong Bum LEE ; Hae Yong LEE ; Jae Seung YANG ; Baek Keun LIM
Journal of the Korean Pediatric Society 1997;40(1):129-133
Early onset cerebellar ataxia with retained tendon reflexes is clinical syndrome characterized by progressive cerebelar ataxia of unknown etiology with an onset within the first two decades. This disorder was distinguished from Friedreich's ataxia by the preservation of the tendon reflexes. We have experienced a case of early onset cerebellar ataxia with retained tendon reflexes which was diagnosed by clinical features, eletrophysiologic studies, and MRI scan. This 8 year-old male patient had suffered from gait ataxia with delayed growth and development since 3 years of age. A brief review of the related literatures was also made.
Ataxia
;
Cerebellar Ataxia
;
Child
;
Friedreich Ataxia
;
Gait Ataxia
;
Growth and Development
;
Humans
;
Magnetic Resonance Imaging
;
Male
;
Reflex, Stretch*
;
Spinocerebellar Degenerations*
;
Tendons*
10.A Case of Early Onset Cerebellar Ataxia with Retained Tendon Reflexes.
Jong Bum LEE ; Hae Yong LEE ; Jae Seung YANG ; Baek Keun LIM
Journal of the Korean Pediatric Society 1997;40(1):129-133
Early onset cerebellar ataxia with retained tendon reflexes is clinical syndrome characterized by progressive cerebelar ataxia of unknown etiology with an onset within the first two decades. This disorder was distinguished from Friedreich's ataxia by the preservation of the tendon reflexes. We have experienced a case of early onset cerebellar ataxia with retained tendon reflexes which was diagnosed by clinical features, eletrophysiologic studies, and MRI scan. This 8 year-old male patient had suffered from gait ataxia with delayed growth and development since 3 years of age. A brief review of the related literatures was also made.
Ataxia
;
Cerebellar Ataxia
;
Child
;
Friedreich Ataxia
;
Gait Ataxia
;
Growth and Development
;
Humans
;
Magnetic Resonance Imaging
;
Male
;
Reflex, Stretch*
;
Spinocerebellar Degenerations*
;
Tendons*