OBJECTIVES: Gonadal hormone is essential for the health of postmenopausal women, however, few studies have focused on the epidemiological distribution of gonadal hormones in postmenopausal women in very late postmenopausal women. This study aims to investigate and analyze the differences of serum gonadal hormone content and its influential factors among female centenarians in Hainan, China. METHODS: The questionnaire and physical examination data of 741 female centenarians and 401 elderly females in Hainan Province were collected, and venous blood samples were taken to detect the indexes of lipid metabolism, bone metabolism, and gonadal hormone. The differences of gonadal hormones and relavant factors in female centenarians were analyzed and compared. RESULTS: The serum levels of estradiol and progesterone of female centenarians were significantly higher than those of the elderly females (both P<0.001). The serum levels of estradiol and testosterone of ethnic minority centenarians were higher than those in Han nationality (P<0.001), and the serum estradiol and testosterone concentrations were relatively higher when the daily activities were more than 10 min (both P<0.05). Serum estradiol concentration was negatively correlated with apolipoprotein A-I, high density lipoprotein, triglyceride and bone formation markers such as calcium, inorganic phosphorus and vitamin D3, and was positively correlated with the special sequence of β-collagen (markers of bone resorption) (all P<0.01). CONCLUSIONS For the extremely late postmenopausal women (such as centenarians), there may be characteristic expressions of gonadal hormones, especially estradiol. There is an unprotective correlation of serum estradiol with lipid metabolism index and bone metabolism index in female centenarians, so it is necessary to evaluate the estrogen content and the use of estrogen therapy in postmenopausal women.
Aged ; Aged, 80 and over ; Centenarians ; China ; Cross-Sectional Studies ; Estradiol ; Estrogens ; Ethnicity ; Female ; Humans ; Minority Groups ; Testosterone

Introduction: Basal cell carcinoma (BCC) is the most common type of malignancy worldwide. The incidence of BCC is positively associated with increasing age; thus, centenarians, defined as those aged 100 years and above, become a vulnerable population to developing malignancy. As a person ages, risk factors such as chronic sun exposure, ionizing radiation, and immunosuppres- sion induce mutations that contribute to tumor formation. Impaired DNA repair capacity in response to carcinogens and immune function dysfunction also increases BCC risk in the elderly. Currently, studies among centenarians with high-risk basal cell car- cinoma treated with surgical interventions are limited. Case report: Presented herewith is a case of a 101-year-old female with a 15-year history of hyperpigmented, hyperkeratotic plaque over the right malar area and a one-year history of progressive pain (PS 10/10) and enlargement of the lesion, forming an ulcerated, hyperpigmented tumor. Laboratory workup showed normal findings. Histopathology was signed out as a pigmented nodulocystic basal cell carcinoma. Moh’s micrographic surgery (MMS) and cheek advancement flap were performed with good wound healing and no perioperative complications. Conclusion Despite the limited options of medical and physical management due to decreased life expectancy of centenar- ians, MMS remains the standard of therapy in high-risk BCC. MMS with reconstructive surgery is generally a safe and effective modality with no increased risk of peri- and post-operative complications.
Carcinoma, Basal Cell ; Centenarians

Objective: To investigate body mass index (BMI) level, identify the main type of nutritional problem, and describe the population distribution characteristics of BMI among Chinese people aged 80 years or above. Methods: The data of 9 481 oldest-old individuals were obtained from the 2017-2018 Chinese Longitudinal Healthy Longevity Survey. The Lambda-Mu-Sigma method, weighted estimates of BMI, and comparisons by BMI quintiles were used to describe the BMI level and distribution characteristics among the oldest-old. Results: The average age of the participants was (91.9±7.7) years, with P₅₀ of the weighted BMI at 21.9 (95%CI: 21.8-22.0) kg/m². The result of BMI level showed a decreasing trend with age, with a rapid decline before age 100, and then the trend became slower. There are about 30% of the oldest-old classified as undernutrition, but the prevalence of overnutrition is only about 10%. The population distribution characteristics by BMI quintiles showed the oldest-old with lower BMI levels were likely to have the following characteristics: sociodemographically, to be older, female, ethnic minority, unmarried/divorced/widowed, rural residents, illiterate, with inadequate living expenses, located in Central, South, or Southwest China; regarding lifestyles, lower BMI levels were observed for participants who were smoking, not exercising, lack of leisure activities, or with poor dietary diversity; considering functional status, participants with lower BMI levels were those who have poor chewing ability, disability in activities of daily living, cognitive impairment, hearing loss, visual impairment, or poor self-rated health status. The oldest-old with higher BMI levels were likely to have heart disease, hypertension, cerebrovascular disease, and diabetes. Conclusions: The overall BMI level was low among the Chinese oldest-old and it showed a downward trend with age. Currently, the main nutritional problem among the Chinese oldest-old was undernutrition rather than overweight or obesity. Management of healthy lifestyles, functional status, and diseases would be helpful to reduce the risk of undernutrition among the oldest-old.
Aged, 80 and over ; Female ; Humans ; Activities of Daily Living ; Body Mass Index ; East Asian People ; Ethnicity ; Malnutrition ; Minority Groups ; Male ; Centenarians ; Nonagenarians

No abstract available.
Aged, 80 and over* ; Humans

A case of radicular pain that resulted from a gas-filled intradural cyst in an 80-year-old male is described. Temporary improvement of radicular pain was observed after CT-guided aspiration. However, recurrent radicular pain led to surgical treatment. In this report, the authors document the radiologic and intraoperative features of a gas-filled intradural cyst that migrated into the nerve root, and propose an optimal treatment plan based on a review of the literature.
Aged, 80 and over ; Humans ; Male

This study aims to determine pre-morbid parameters as possible predictors of outcome of hip fracture in octogenarians with unstable intertrochanteric fracture treated operatively. Presence of co-morbidities, pre-injury level of ambulation, type of surgery, and period of delay in surgery were considered, and their effect on the post-operative outcome was evaluated using the Harris Hip Score. The computed probability of survival of octogenarians who had surgery was approximately 11 months. In patients with two or more co-morbidities, there is a significant effect on Harris Hip Score in terms of pain and deformity. Delay in surgery of more than two weeks significantly decreased the distance travelled at one year. The overall recovery is correlated to preinjury level of ambulation and delay in surgery. Patients with intertochanteric fracture in this age group, who have less co-morbidities and with more independent ambulation, are good candidates for timely operative treatment.
Aged, 80 and over ; Hip Fractures

No abstract available.
Aged, 80 and over* ; Dementia* ; Humans

Background: Maintaining optimal well-being of the elderly is now a major concern since their numbers are expected to swell in the next decades. Thus, there is a need to focus on the health and psychosocial status and needs of our older persons. Objective: To describe the biopsychosocial profile and needs of older persons in Davao City. Methodology: This study utilized secondary data obtained from the OPS 2009 survey after informed consent was sought from the DCOP-RG. The OPS 2009 survey was developed by a multidisciplinary group of professionals commissioned by the Davao City Sangguniang Panglungsod in order to create a basis for the implementing rules of the expanded senior citizen act for Davao City. It included 398 respondents age 60 and above who gave consent, representing the population of older persons from the different areas in Davao City. Data gathering was done by a team of trained interviewers. Anonymized gathered in OPS 2009 survey was utilized for this present study. Descriptive statistics were used to summarize the data. Results: There was an equal sex distribution among the respondents. Majority were married, widowed and Roman Catholics, 76.6% of the respondents believed that they were in good health. 60.1% of the respondents had previous admissions but even so, majority (87.9%) had someone to help take care of them during their admissions. Psychosocial status of the older persons was favorable in general. Majority (72.2%) still engage in recreational activities. Furthermore, the respondents have a happy disposition in life wherein majority have a perceived happy mood left contented and at peace. Almost all (98%) still feels needed by their kin and friends. Perceived health needs include better medical benefits while perceived psychosocial needs include financial and moral support. Conclusion: The study showed that older persons in Davao City perceived themselves to be happy, contented, calm, at peace and important to their families. However, since most were diagnosed with chronic illnesses such as hypertension, arthritis, diabetes, and asthma; health related needs and provision of better medical benefits topped their list. Financial support and psychosocial support from their families, government and non-government institutions were also listed as needs. In general, they envisioned Davao to be an older person friendly place with program that put elderly welfare, safety and protection at the forefront.
Aged 80 and over ; Aged ; FRAIL ELDERLY

Primary carcinoma of the urethra is quite rare. The causes of the disease are poorly understood. It is the only urologic malignancy. known to be less common in males than females, despite of the greater length and complexity of the urethra in the male. We report a case of carcinoma of the urethra in 81 years old male patient.
Aged, 80 and over ; Female ; Humans ; Male* ; Urethra*

We report a case of an 81 year-old man with multiple, giant porokeratosis, who had variable-sized erythematous, scaly plaques, ranging from 3x4cm to 10x2cm, on his trunk, extremities and genital area. The skin lesions appeared 20 years ago and had increased gradually and slowly, both in size and number. Histologic examination revealed a typical cornoid lamella and loss of the underlying granular layer. Giant porokeratosis was diagnosed on the basis of overwhelming clinical features and characteristic histologic findings. Giant porokeratosis is a rare clinical condition among several subtypes of porokeratosis.
Aged, 80 and over ; Extremities ; Humans ; Porokeratosis* ; Skin