No abstract available.
Cefazolin* ; Vasculitis*

No abstract available.
Cefazolin* ; Erythromycin* ; Latency Period (Psychology)* ; Membranes* ; Rupture*

The minimal inhibitory concentration(MIC) of cephalosporin derivatives, (cephaloridine, cefazolin sodium, cephradine, cephapirin aodium, cephacetrile sodium, and cephalexin from various Korean drug companies) for Staphykcoccus aureus ATCC 25923 and Escherichia coli ATCC 25922 was measured by the tube dilution method, using Mueller-Hinton broth. The results obtained were as follows: 1) The MIC of each individual cephalosporin derivative, although produced by different manufacturers, was similiar or equal. 2) Against Staphyloeoccus aureus, cephaloridine and cephapirin had the lowest MIC while cephradine and, cephalexin the highest. Against E. coli, cephaloridine and cefazolin had the lowest MIC while cephradine and cephalexin the highest. 3) The MIC against Staphylococcus aureus was l5.6 to 250 times lower than that against E. coli in all cephalosporin derivatives. 4) The MIC against Staphylococcus aureus ranges from 0.0125 to l.0ug/ml and against E. coli from 1. 56 to 25ug/ml in all cephalasporin derivatives.
Cefazolin ; Cephacetrile ; Cephalexin ; Cephaloridine ; Cephapirin ; Cephradine ; Escherichia coli ; Staphylococcus aureus

7-ACA(7-aminocephalosporanic acid) and ACT(aminocephalosporanic thiazine) are basic materials for development of 2nd and 3rd generation cephalosporin. Occupational asthmas(OA) induced by these materials have been very rarely reported. We had experienced 2 cases of OA by them. One was 26 year-old male laboratorian involving 7ACA manufacturing directly. The other case was 40 year-old male asthmatics working at the ware house keeping 7ACA and ACT, not directly making these. The result of skin prick test with 55 common inhalant allergens and 7ACA, ACT and several cephalosporins including Cefazolin, Cefuroxime, Ceftazidime, Cefotaxime, Ceftriaxone and Cefotetan. First case revealed positive reactions to 7ACA and Ceftriaxone, but second case, only positive to ACT. In first case, bronchial challenge with 7ACA only showed positive, but in second, those with 7ACA and ACT both showed positive, though negative to 7ACA in skin test.
Adult ; Allergens ; Asthma, Occupational* ; Cefazolin ; Cefotaxime ; Cefotetan ; Ceftazidime ; Ceftriaxone ; Cefuroxime ; Cephalosporins ; Humans ; Male ; Skin ; Skin Tests

OBJECTIVE: Post-craniotomy seizure (PCS) is reported only rarely. However, our department noted a 433% increase in PCS for a year beginning September 2010, especially after cerebrovascular surgery. Our goal was to identify the cause of our unusual outbreak of PCS. METHODS: For almost one year after September 2010, cases of PCS increased significantly in our department. We analyzed 973 patients who had received a major craniotomy between January 2009 and November 2011. We included seizures that occurred only in the first 24 postoperative hours, which we defined as early PCS. After verifying the presence of PCS, we analyzed multiple seizure-provoking factors and their relation to the duration and character of seizure activity. RESULTS: Overall PCS incidence was 7.2% (70/973). Cefazolin (2 g/L saline) was the antibiotic drug used for intraoperative irrigation in 88.4% of the operations, and no PCS occurred without intraoperative cefazolin irrigation. When analyzed by operation type, clipping surgery for unruptured aneurysms was the most frequently associated with PCS (80%). Using logistic regression, only 2 g cefazolin intraoperative irrigation (p=0.024) and unruptured aneurysm clipping surgery (p<0.001) were associated with early PCS. The seizure rate of unruptured aneurysm clipping surgery using 2 g cefazolin intraoperative irrigation was 32.9%. CONCLUSION: Intraoperative cefazolin irrigation must be avoided in patients undergoing craniotomy, especially for clipping of unruptured aneurysms, because of the increased risk of early PCS.
Aneurysm ; Anti-Bacterial Agents* ; Cefazolin ; Craniotomy ; Humans ; Incidence ; Logistic Models ; Seizures*

This paper is presented to report the results of urinary quantitative culture and drug sensitivity tests for isolated micro-organisms in this study. Studies were done on 172 cases from the department of Urology, Eul Ji General Hospital during the period from Jan. 1979 up to Dec. 1980. 1. Quantitative urine culture in 172 cases were performed and of these, 89 cases grew micro-organism wile the remaining 83 cases showed no growth. Among the 89 cases, 67 cases (75. 2%) revealed significant bacteriuria with colony count over 10 5/ml in urine while 22 cases (24. 8%) were below 10 5/ml. Radio of Male: Female is 29 : 38 2. 55 cases (82. 1%) among the 67 cases with significant bacteriuria could the bacteria be identified on a smear and Gram stain. 54 cases (80.6%) of the 67 significant bacteriuria casts revealed pyuria of more than 5/HPF while 13 cases (19.4%) were below 5/HPF 3. 60 cases (89. 6%) of the 67 cases significant bacteriuria has Gram (-) bacilli while 7 cases(10.4 %) were Gram (+) cocci by direct smear. The frequency of isolated organism were as following E. coli ....33 cases (49. 3%). Pseudomonas ....11 cases (16. 4%) Enterobactor ....6 cases(9.0%) Proteus and stapbylo. Aureus .....4 cases (5.8%) respectively. 4. On the whole, all isolated micro-organisms showed considerable susceptibility to panimycin (82. 7%) and then frequency of susceptible drug were and then the frequency of susceptible drug were Cefamezine, Kedacillin, Gentamicin.
Anti-Bacterial Agents ; Bacteria ; Bacteriuria ; Cefazolin ; Female ; Gentamicins ; Hospitals, General ; Humans ; Male ; Proteus ; Pseudomonas ; Pyuria ; Urology

This paper is presented to report the results of urinary quantitative culture and drug sensitivity tests for isolated micro-organisms in this study. Studies were done on 172 cases from the department of Urology, Eul Ji General Hospital during the period from Jan. 1979 up to Dec. 1980. 1. Quantitative urine culture in 172 cases were performed and of these, 89 cases grew micro-organism wile the remaining 83 cases showed no growth. Among the 89 cases, 67 cases (75.2%) revealed significant bacteriuria with colony count over 10 5/ml in urine while 22 cases (24. 8%) were below 105/ml. Radio of Male: Female is 29: 38 2. 55 cases (82.1%) among the 67 cases with significant bacteriuria could the bacteria be identified on a smear and Gram stain. 54 cases (80.6%) of the 67 significant bacteriuria casts revealed pyuria of more than 5/HPF while 13 cases (19.4%) were below 5/HPF 3. 60 cases(89. 6%) of the 67 cases significant bacteriuria has Gram (-) bacilli while 7 cases(10.4 %) were Gram (+) cocci by direct smear. The frequency of isolated organism were as following E. coli 33 cases (49. 3%). Pseudomonas 11 cases(16.4%) Enterobactor 6 cases(9.0%) Proteus and stapbylo. Aureus 4 cases(5.8%) respectively. 4. On the whole, all isolated micro-organisms showed considerable susceptibility to panimycin (82. 7%) and then frequency of susceptible drug were and then the frequency of susceptible drug were Cefamezine, Kedacillin, Gentamicin.
Bacteria ; Bacteriuria ; Cefazolin ; Female ; Gentamicins ; Hospitals, General ; Humans ; Lymphography* ; Male ; Proteus ; Pseudomonas ; Pyuria ; Urology

The antibacterial activity of 11 domestic topical antibiotic eye drops were examed by use of Reddish method, in vitro test. 5 clinical strains which were recovered as common pathogens of corneal ulcer, were inoculated into the diluted antibiotics added with 1% human serum, and 0.01 ml were plated for bacterial survival at 0.5, 1, 2, 4, 8, 16. and 24 hours. Our result showed that gentamicin eye drops effective in Gram negative strains and penicil-line and cefazoline eye drops were effective in Gram positive strains. These results indicated that gentamicin and cefzolin eye drops in combination would be covered the common ocular pathogenic bacteria.
Anti-Bacterial Agents* ; Bacteria ; Cefazolin ; Corneal Ulcer ; Gentamicins ; Humans ; Ophthalmic Solutions

A 52-year-old man undergoing continuous ambulatory peritoneal dialysis presented with two consecutive episodes of peritonitis caused by unusual organisms, namely, Brevibacterium and Pantoea agglomerans. The patient was successfully treated with a 2-week course of cefazolin and ceftazidime for the Brevibacterium-associated peritonitis, and a 3-week course of gentamicin for the P. agglomerans-associated peritonitis. Although these environmental organisms are rarely responsible for human infection, the number of reported cases of human infection by these unusual organisms has increased. This report emphasizes the potential for infection by environmental organisms in patients undergoing peritoneal dialysis.
Brevibacterium ; Cefazolin ; Ceftazidime ; Gentamicins ; Humans ; Middle Aged ; Pantoea ; Peritoneal Dialysis ; Peritoneal Dialysis, Continuous Ambulatory ; Peritonitis

A bacterial study of the conjunctival sac of 115 patients with an anophthalmic eye has compared the kinds of normal flora in the conjunctival sac of normal and anophthalmic eyes and investigated the susceptibility of the isolated bacteria to various antibiotics. Detection rate of bacteria were 35.7% and 69.6% in normal and anophthalmic eyes, respectively. In normal eyes S. epidermidis(40.4%) were isolated more frequently than S. aureus(21.3%), but the detection rate for each bacteria in anophthalmic eyes showed no significant differences. The incidence rate in kinds of bacterial flora in both conjunctival sacs of a person who has one anophthalmic eye was 37.5%, lower than that of a person with normal eyes(71.4% to 96.5%). Bacteria isolated from normal and anophthalmic conjunctiva were similarly sensitive to amikacin, cefazolin, erythromycin, oxacillin. and tobramycin and were resistant to ampicillin and penicllin.
Amikacin ; Ampicillin ; Anophthalmos ; Anti-Bacterial Agents ; Bacteria ; Cefazolin ; Conjunctiva ; Erythromycin ; Eye ; Humans ; Incidence ; Oxacillin ; Tobramycin