1.Risk Factor Analysis for Development of Asymptomatic Carotid Stenosis in Koreans.
Yun Jeong LIM ; Young Wook KIM ; Yeon Hyen CHOE ; Chang Seok KI ; Sue Kyung PARK
Journal of Korean Medical Science 2006;21(1):15-19
Many risk factors for atherosclerosis have been proposed to identify high risk individuals. We conducted a retrospective study to determine the risk factors for development of carotid stenosis (CS) in Koreans. Database of 2,805 subjects who underwent a check up of carotid artery for health examination were analyzed. Stenosis (%) of common carotid artery or proximal internal carotid artery was examined with ultrasonography. Subjects were divided into 2 groups (Group I; CS <10%, Group II; CS > or =30%). We compared demographic, laboratory and clinical data between 2 groups to determine the risk factors of CS. One hundred ninety seven subjects (7.0%) were categorized as Group II. At age- and sex-adjusted multivariate analysis, diabetes mellitus, hypertension, cerebrovascular disease, ischemic heart disease, hyperlipidemia, aspirin medication, current smoking, fasting glucose, total cholesterol, low density lipoprotein-cholesterol (LDL-C) and leukocyte count were significant risk factors of CS. At stepwise logistic regression analysis, age, hypertension, hyperlipidemia, LDL-C and leukocyte count were independent risk factors. At subgroup analysis by smoking, age and leukocyte count were independent risk factors in smoker and age and hypertension in nonsmoker.
Adult
;
Age Factors
;
Aged
;
Carotid Stenosis/blood/*epidemiology/etiology
;
Cholesterol/blood
;
Comparative Study
;
Female
;
Humans
;
Korea/epidemiology
;
Lipoproteins, LDL Cholesterol/blood
;
Logistic Models
;
Male
;
Middle Aged
;
Multivariate Analysis
;
Prevalence
;
Retrospective Studies
;
Risk Factors
;
Smoking/adverse effects