1.Treatment of Hemichoreoathetosis with Arrhythmic Proximal Tremor after Stroke: The Role of Zona Incerta as a Target for Deep Brain Stimulation
Andrei KOERBEL ; Augusto Radünz DO AMARAL ; Helena Bedatti ZEH ; Eduardo WOLLMANN ; Renata Fabiola Heil KOERBEL ; Carla MORO ; Alexandre Luiz LONGO
Journal of Movement Disorders 2019;12(1):47-51
Deep brain stimulation (DBS) of the zona incerta has shown promising results in the reduction of medically refractory movement disorders. However, evidence supporting its efficacy in movement disorders secondary to hemorrhagic stroke or hemichoreoathetosis is limited. We describe a 48-year-old man who developed progressive hemichoreoathetosis with an arrhythmic, proximal tremor in his right arm following a thalamic hemorrhagic stroke. Pharmacological treatment was carried out with no change in the Abnormal Involuntary Movement Scale (AIMS) score after 4 weeks (14). After six sessions of botulinum toxin treatment, a subtle improvement in the AIMS score (13) was registered, but no clinical improvement was noted. The arrhythmic proximal movements were significantly improved after DBS of the zona incerta with a major decrease in the patient’s AIMS score (8). The response to DBS occurring after the failure of pharmacological and botulinum toxin treatments suggests that zona incerta DBS may be an alternative for postthalamic hemorrhage movement disorders.
Abnormal Involuntary Movement Scale
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Arm
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Botulinum Toxins
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Chorea
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Deep Brain Stimulation
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Hemorrhage
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Herpes Zoster
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Humans
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Middle Aged
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Movement Disorders
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Stroke
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Tremor
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Zona Incerta
2.Pearls and Potential Pitfalls for Correct Diagnosis of Ovarian Cystadenofibroma in MRI:A Pictorial Essay
Giacomo AVESANI ; Gianluca CALIOLO ; Benedetta GUI ; Federica PETTA ; Camilla PANICO ; Viviana La MANNA ; Francesca MORO ; Antonia Carla TESTA ; Giovanni SCAMBIA ; Riccardo MANFREDI
Korean Journal of Radiology 2021;22(11):1809-1821
Ovarian cystadenofibroma is a benign ovarian tumor that is characterized by a consistent percentage of masses, which remain indeterminate in ultrasonography and require magnetic resonance (MR) investigation; they may mimic borderline or malignant lesions. Three main morphologic patterns, resembling different ovarian neoplasms, can be identified in cystadenofibromas:multilocular solid lesions, unilocular cystic lesions with parietal thickening, and purely cystic masses. However, a cystoadenofibroma has typical features, such as T2-weighted hypointensity associated with no restrictions in diffusion-weighted imaging (the so-called “dark-dark appearance”) and progressive post-contrast enhancement (type I perfusion curve). The purpose of this study was to review the features of ovarian cystadenofibromas in MR imaging and to suggest pearls and pitfalls regarding their correct diagnosis.