1.Comparison of the Clinical Features of Apical Hypertrophic Cardiomyopathy Versus Asymmetric Septal Hypertrophy in Korea.
Hyun Suk YANG ; Jae Kwan SONG ; Jong Min SONG ; Duk Hyun KANG ; Cheol Whan LEE ; Myeong Ki HONG ; Jae Joong KIM ; Seong Wook PARK ; Seung Jung PARK
The Korean Journal of Internal Medicine 2005;20(2):111-115
BACKGROUND: We sought to test whether patients with apical hypertrophic cardiomyopathy (APH) have different clinical features compared to those with typical asymmetric septal hypertrophy (ASH). METHODS: Among 32, 534 patients who underwent routine echocardiography at Asan Medical Center from January 2000 to December 2001, 305 patients (0.9%), who were finally diagnosed with hypertrophic cardiomyopathy (HCMP), were evaluated. The type of HCMP was classified according to the echocardiographic findings. RESULTS: ASH was the most frequent type (n=160, 53%, group I), and APH was the second most frequent (n=91, 30%, group II). Mean age (60.8 +/- 10 vs. 48.2 +/- 14 years, p< 0.001) and prevalence of hypertension (32% vs. 19%, p=0.022) were significantly higher in group II than in group I. Family history of HCMP (4.4% vs. 0% p=0.043) and sudden cardiac death (8.8% vs. 1.1% p=0.014) was more prevalent in group I. During the follow-up period of 32.0 +/- 37.2 months, cardiac events occurred at a significantly higher rate in group I (25.5% vs. 8.8%, p=0.003). CONCLUSION: APH comprises a significant proportion of HCMP in Korea and patients with APH show different clinical features compared to those with ASH.
Cardiomyopathy, Hypertrophic/epidemiology/*ultrasonography
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Comparative Study
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Echocardiography
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Female
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Follow-Up Studies
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*Heart Septum/ultrasonography
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*Heart Ventricles/ultrasonography
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Humans
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Korea/epidemiology
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Male
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Middle Aged
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Prevalence
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Retrospective Studies