Cardiomyopathies ; diagnosis ; pathology ; Humans

Cardiomyopathies ; diagnosis ; etiology ; therapy ; Humans

Cardiomyopathies ; diagnosis ; etiology ; Child ; Humans

BACKGROUND: The weight, shape and consistency of the heart, and the thickness of the ventricular wall are used as parameters for evaluating postmortem heart and diagnosing cardiomyopathy at autopsy. METHODS: The weight and volume of the ventricles and the thickness of the left ventricular wall of 58 hearts were measured and analyzed. RESULTS: In the group of dilated hearts, the ventricular weight, ventricular volume, ventricular volume/ventricular weight, and left ventricular volume/right ventricular volume increased, whereas ventricular wall thickness decreased. In the group of hypertrophied hearts, the ventricular weight, ventricular volume, and thickness of the ventricular wall increased but ventricular volume/ventricular weight and left ventricular volume/right ventricular volume did not change significantly. In the group of undetermined hearts, it was later found that four of the cases should have been included in the dilated heart group and another two cases in the hypertrophied heart group. CONCLUSIONS: In addition to conventional methods, the measuring ventricular volume is useful for evaluating a postmortem heart and may suggest postmortem differential diagnoses of dilated or hypertrophied forms of secondary cardiomyopathies.
Autopsy ; Cardiomyopathies ; Diagnosis, Differential ; Heart

Amyloidosis ; classification ; diagnosis ; Cardiomyopathies ; classification ; diagnosis ; Humans

This paper introduces the troponin, a new gold standard for diagnosis of myocardial infarction and role of troponin in other diseases. The authors introduced also some new standards for diagnosis of the myocardial infarction such as cut-off value, isoenzyme CK-MB, GOT, myoglobin and LDH
Troponin ; Cardiomyopathies ; Infarction ; diagnosis ; Myocardial Infarction

Cardiomyopathies ; diagnosis ; therapy ; Child ; Eosinophilia ; diagnosis ; therapy ; Humans ; Male

Cardiomyopathies ; diagnosis ; Diagnostic Imaging ; Humans ; Ventricular Dysfunction, Left ; diagnosis

Amyloid Neuropathies, Familial/diagnosis* ; Cardiomyopathies/diagnosis* ; Humans ; Prealbumin

Carnitine is essential for the transfer of long-chain fatty acids from the cytosol into mitochondria for subsequent beta-oxidation. A lack of carnitine results in impaired energy production from long-chain fatty acids, especially during periods of fasting or stress. Primary carnitine deficiency (PCD) is an autosomal recessive disorder of mitochondrial beta-oxidation resulting from defective carnitine transport and is one of the rare treatable etiologies of metabolic cardiomyopathies. Patients affected with the disease may present with acute metabolic decompensation during infancy or with severe cardiomyopathy in childhood. Early recognition of the disease and treatment with L-carnitine may be life-saving. In this review article, the pathophysiology, clinical presentation, diagnosis, treatment and prognosis of PCD are discussed, with a focus on cardiac involvements.
Cardiomyopathies* ; Carnitine* ; Cytosol ; Diagnosis ; Fasting ; Fatty Acids ; Humans ; Mitochondria ; Prognosis