5.Current Status of Endoscopic Papillectomy for Ampullary Tumors.
Jong Ho MOON ; Hyun Jong CHOI ; Yun Nah LEE
Gut and Liver 2014;8(6):598-604
Detection of tumors of the ampulla of Vater, including ampullary adenoma, has been improved by routine screening endoscopic procedures and imaging modalities. Endoscopic resection by endoscopic papillectomy is rapidly replacing classic surgical resection and is a less invasive procedure. Endoscopic resection can have a role not only in the final histopathologic diagnosis but also as a definite therapeutic option. However, the indications for endoscopic resection are not fully established, and endoscopic procedures are not standardized. Significant complications, including severe pancreatitis, intractable bleeding and duodenal perforation, are rare but can occur, especially in less experienced hands. Severe pancreatitis is the most feared complication, but it can be prevented by pancreatic duct stent insertion in most cases. However, in some cases, pancreatic stenting can be challenging after resection. Incomplete resections are sometimes performed to avoid complications. Endoscopic surveillance is also important for identifying and managing remnant adenomatous tissue or recurrent lesions. Further technical development is needed to expand the indications for this procedure, minimize complications and ensure a high success rate.
Adenoma/pathology/*surgery
;
Ampulla of Vater/pathology/*surgery
;
Carcinoma/pathology/*surgery
;
Common Bile Duct Neoplasms/pathology/*surgery
;
Endoscopy, Digestive System
;
Humans
6.Simultaneous medullary carcinoma, papillary carcinoma and granulomatous inflammation of the thyroid.
Kamal KATARIA ; Rajni YADAV ; Chitra SARKAR ; Asis Kumar KARAK
Singapore medical journal 2013;54(7):e146-8
Thyroid tumours with both papillary and medullary carcinoma features are rare and represent less than 1% of all thyroid malignancies. These tumours have a different clinical presentation and biological behaviour from tumours that have only papillary or medullary carcinoma features. The phenomenon of mixed thyroid tumours can be observed in two settings--a mixed tumour showing dual differentiation, or a collision tumour. For a precise diagnosis of this rare mixed thyroid carcinoma, fine needle aspiration cytology results should be correlated with serum calcitonin and thyroglobulin levels. The diagnosis should also be confirmed using immunocytochemistry. Surgery is the treatment of choice, and the role of postoperative radioiodine is controversial. We herein report the case of a 35-year-old man with a mixed medullary-papillary carcinoma of the thyroid, which presented with C-cell hyperplasia, granulomatous inflammation and metastasis to the cervical lymph nodes. The patient was treated with total thyroidectomy and nodal clearance. This case highlights the need for awareness of coexistent entities as they warrant separate treatments.
Adult
;
Carcinoma, Medullary
;
pathology
;
surgery
;
Carcinoma, Papillary
;
pathology
;
surgery
;
Humans
;
Inflammation
;
pathology
;
Lymphatic Metastasis
;
Male
;
Neoplasms, Multiple Primary
;
pathology
;
surgery
;
Photomicrography
;
Thyroid Neoplasms
;
pathology
;
surgery
;
Thyroidectomy
7.Diagnosis and substaging of pT1 bladder cancer.
Liang CHENG ; Wen-bin HUANG ; Su-qin ZHENG ; Jie ZHENG
Chinese Journal of Pathology 2007;36(9):636-639
9.A Case of Combined Hepatocellular-Cholangiocarcinoma with Underlying Schistosomiasis.
Chang Kyun HONG ; Jin Mo YANG ; Bong Koo KANG ; Jin Dong KIM ; Young Chul KIM ; U Im CHANG ; Jin Young YOO
The Korean Journal of Internal Medicine 2007;22(4):283-286
Combined hepatocellular-cholangiocarcinoma is a rare form of primary liver cancer showing features of both hepatocellular and biliary epithelial differentiation. We report here on a case with collision tumor, which apparently was the coincidental occurrence of both hepatocellular carcinoma and cholangiocarcinoma underlying schistosomiasis. A 39-year-old-Philippine female was transferred to our hospital for evaluation of a liver mass that was found on ultrasonography at a local hospital. HBsAg and Anti-HCV were negative and serum alpha-fetoprotein (AFP) level was normal. The tumor mass was histologically diagnosed as adenocarcinoma by sono-guided biopsy before the operation. Partial lobectomy was performed and we histologically identified the concurrent occurrence of hepatocellular carcinoma and cholangiocarcinoma, (a "collision type carcinoma").
Adenocarcinoma/diagnosis/pathology/surgery
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Adult
;
Carcinoma, Hepatocellular/*diagnosis/pathology/surgery
;
Cholangiocarcinoma/*diagnosis/pathology/surgery
;
Female
;
Humans
;
Schistosomiasis/*physiopathology
10.Salivary duct carcinoma in the neck.
Mohd Izani SHIYUTI ; Irfan MOHAMAD ; Shah Jihan Wan DIN ; Venkatesh R NAIK ; Venkata M K BHAVARAJU
Annals of the Academy of Medicine, Singapore 2011;40(10):473-474
Carcinoma, Ductal
;
pathology
;
surgery
;
Female
;
Head and Neck Neoplasms
;
pathology
;
surgery
;
Humans
;
Middle Aged
;
Neck Dissection
;
Salivary Ducts
;
pathology
;
surgery