1.Synchronous primary carcinomas of the bladder and prostate.
Sheng-Hui LEE ; Phei-Lang CHANG ; Shao-Ming CHEN ; Guang-Huan SUN ; Chien-Lun CHEN ; Biing-Yir SHEN ; Ya-Shen WU ; Ke-Hung TSUI
Asian Journal of Andrology 2006;8(3):357-359
AIMTo determine the incidence of adenocarcinoma of the prostate for patients undergoing radical cystoprostatectomy for bladder cancer in Taiwan.
METHODSA total of 248 patients in Taiwan who were histologically confirmed for transitional cell carcinoma of the bladder underwent cystoprostatectomy. Histopathologic evaluation of the prostate specimens sectioned at 5 mm intervals was performed.
RESULTSOf the 248 patients, 10 (4.03%) were found to have prostate cancer. Of the 10 cases of unsuspected prostate cancer, eight proved to be at stage T1 or T2, and two at T3 and T4, respectively. This rate of incidentally found prostate cancer amongst our bladder cancer patients appeared to be lower than that found in bladder cancer patients in similar studies in USA.
CONCLUSIONAlthough the incidence of incidental prostate cancer in patients in Taiwan with bladder cancer is not high compared with that in Western countries, we suggest that digital rectal examination and prostate-specific antigen (PSA) are important screening tools for men with bladder cancer, especially for those aged 60 years and older in Taiwan.
Carcinoma, Transitional Cell ; pathology ; surgery ; Humans ; Male ; Neoplasm Staging ; Prostatectomy ; Prostatic Neoplasms ; complications ; surgery ; Urinary Bladder Neoplasms ; complications ; pathology ; surgery
2.Ipsilateral synchronous renal cell carcinoma and transitional cell carcinoma.
Jin Woo LEE ; Moon Jae KIM ; Joon Ho SONG ; Ju Hong KIM ; Joon Mee KIM
Journal of Korean Medical Science 1994;9(6):466-470
*Carcinoma, Renal Cell/pathology/surgery
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*Carcinoma, Transitional Cell/pathology/surgery
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Case Report
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Human
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Hypercalcemia/etiology
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Kidney Calculi/complications/surgery
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*Kidney Neoplasms/pathology/surgery
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Kidney Pelvis
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Male
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Middle Age
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*Neoplasms, Multiple Primary/pathology/surgery
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Nephrectomy
3.Metastatic bladder cancer presenting as duodenal obstruction.
Katherine HAWTIN ; Alex KENT ; Carole COLLINS ; Dominic BLUNT
Annals of the Academy of Medicine, Singapore 2009;38(10):914-912
INTRODUCTIONBladder cancer is a common malignancy but presentation with metastatic disease is rare. This is the fi rst reported case of duodenal obstruction as a presentation of metastatic bladder cancer.
CLINICAL PICTUREA middle-aged woman presented with nausea, vomiting, weight loss and intermittent haematuria. Radiology and histology confirmed metastatic bladder cancer to the retroperitoneum encasing the duodenum and causing obstruction.
TREATMENTInsertion of a duodenal stent relieved the obstruction and palliative chemoradiotherapy was initiated.
OUTCOMEThe patient died 15 months after diagnosis.
CONCLUSIONSClinicians and radiologists should be aware of atypical presentations of common malignancies.
Adult ; Carcinoma, Transitional Cell ; drug therapy ; secondary ; Diagnosis, Differential ; Duodenal Obstruction ; diagnosis ; etiology ; surgery ; Fatal Outcome ; Female ; Humans ; Palliative Care ; Retroperitoneal Neoplasms ; complications ; diagnosis ; secondary ; Stents ; Urinary Bladder Neoplasms ; drug therapy ; pathology
4.Predictive value of pretreatment inflammation-based prognostic scores (neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and lymphocyte-to-monocyte ratio) for invasive bladder carcinoma.
Su Min LEE ; Andrew RUSSELL ; Giles HELLAWELL
Korean Journal of Urology 2015;56(11):749-755
PURPOSE: Inflammation-based prognostic scores including neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and lymphocyte-to-monocyte ratio (LMR) are associated with oncologic outcomes in diverse malignancies. We evaluated the predictive value of pretreatment prognostic scores in differentiating nonmuscle invasive (NMIBC) and muscle invasive bladder cancer (MIBC). MATERIALS AND METHODS: Consecutive transurethral resection of bladder tumour (TURBT) cases from January 2011 to December 2013 were analysed retrospectively. Patient demographics, tumour characteristics and prognostic scores results were recorded. Receiver operating characteristics curves were used to determine prognostic score cutoffs. Univariate and multivariate binomial logistic regression analysis was performed to evaluate the association between variables and MIBC. RESULTS: A total of 226 patients were included, with 175 and 51 having NMIBC (stages Ta and T1) and MIBC (stage T2+) groups, respectively. Median age was 75 years and 174 patients were male. The NLR cutoff was 3.89 and had the greatest area under the curve (AUC) of 0.710, followed by LMR (cutoff<1.7; AUC, 0.650) and PLR (cutoff>218; AUC, 0.642). Full blood count samples were taken a median of 12 days prior to TURBT surgery. Multivariate logistic regression analysis identified tumour grade G3 (odds ration [OR], 32.848; 95% confidence interval [CI], 9.818-109.902; p=0.000), tumour size> or =3 cm (OR, 3.353; 95% CI, 1.347-8.345; p=0.009) and NLR> or =3.89 (OR, 8.244; 95% CI, 2.488-27.316; p=0.001) as independent predictors of MIBC. CONCLUSIONS: NLR may provide a simple, cost-effective and easily measured marker for MIBC. It can be performed at the time of diagnostic flexible cystoscopy, thereby assisting in the planning of further treatment.
Aged
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Aged, 80 and over
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Blood Platelets/pathology
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Carcinoma, Transitional Cell/complications/pathology/*surgery
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Female
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Humans
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Inflammation/diagnosis/*etiology
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Leukocyte Count
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Lymphocyte Count
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Male
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Muscle, Smooth/pathology
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Neoplasm Grading
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Neoplasm Invasiveness
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Neoplasm Staging
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Neutrophils/pathology
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Platelet Count
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Predictive Value of Tests
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Prognosis
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Retrospective Studies
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Urinary Bladder Neoplasms/complications/pathology/*surgery