1.Synchronous Triple Primary Lung Cancers: A Case Report.
Hyun Jung YOON ; Ho Yun LEE ; Joungho HAN ; Yoon La CHOI
Korean Journal of Radiology 2014;15(5):646-650
Synchronous primary lung cancers are relatively rare. The accurate diagnosis remains challenging, despite of the routine use of bronchoscopy and computed tomography (CT) of the chest. Herein we report a case of synchronous triple primary cancers of the right lung in a 72-year-old male patient in whom each tumor presented distinct CT imaging findings.
Adenocarcinoma/*diagnosis/pathology/radiography
;
Adenocarcinoma, Mucinous/*diagnosis/pathology/radiography
;
Aged
;
Bronchoscopy
;
Carcinoma, Squamous Cell/*diagnosis/pathology/radiography
;
Diagnosis, Differential
;
Humans
;
Lung Neoplasms/*diagnosis/pathology/radiography
;
Male
;
Neoplasm Staging
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Neoplasms, Multiple Primary
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Positron-Emission Tomography
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Tomography, X-Ray Computed
2.CT Findings of Gallbladder Metastases: Emphasis on Differences According to Primary Tumors.
Won Seok CHOI ; Se Hyung KIM ; Eun Sun LEE ; Kyoung Bun LEE ; Won Jae YOON ; Cheong Il SHIN ; Joon Koo HAN
Korean Journal of Radiology 2014;15(3):334-345
OBJECTIVE: To describe computed tomography (CT) features of metastatic gallbladder (GB) tumors (MGTs) from various primary tumors and to determine whether there are differential imaging features of MGTs according to different primary tumors. MATERIALS AND METHODS: Twenty-one patients who had pathologically confirmed MGTs and underwent CT were retrospectively enrolled. Clinical findings including presenting symptoms, type of surgery, and interval between primary and metastatic tumors were recorded. Histologic features of primary tumor and MGTs including depth of invasion were also reviewed. Imaging findings were analyzed for the location and morphology of MGTs, pattern and degree of enhancement, depth of invasion, presence of intact overlying mucosa, and concordance between imaging features of primary and metastatic tumors. Significant differences between the histologies of MGTs and imaging features were determined. RESULTS: The most common primary tumor metastasized to the GB was gastric cancer (n = 8), followed by renal cell carcinoma (n = 4) and hepatocellular carcinoma (n = 3). All MGTs (n = 21) manifested as infiltrative wall thickenings (n = 15) or as polypoid lesions (n = 6) on CT, similar to the features of primary GB cancers. There were significant differences in the morphology of MGTs, enhancement pattern, enhancement degree, and depth of invasion according to the histology of primary tumors (p < 0.05). Metastatic adenocarcinomas of the GB manifested as infiltrative and persistently enhancing wall thickenings, while non-adenocarcinomatous metastases usually manifested as polypoid lesions with early wash-in and wash-out. CONCLUSION: Although CT findings of MGTs are similar to those of primary GB cancer, they are significantly different between the various histologies of primary tumors.
Adenocarcinoma/pathology/radiography/secondary
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Adult
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Aged
;
Carcinoma, Hepatocellular/pathology/radiography/secondary
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Carcinoma, Renal Cell/pathology/radiography/secondary
;
Carcinoma, Squamous Cell/pathology/radiography/secondary
;
Diagnosis, Differential
;
Female
;
Gallbladder Neoplasms/pathology/*radiography/*secondary
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Humans
;
Kidney Neoplasms/pathology
;
Liver Neoplasms/pathology
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Male
;
Melanoma/pathology/radiography/secondary
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Middle Aged
;
Neoplasm Invasiveness/radiography
;
Retrospective Studies
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Stomach Neoplasms/pathology
;
*Tomography, X-Ray Computed
3.A Case of Basaloid Squamous Cell Carcinoma of Rectosigmoid Colon.
Tae Hwan HA ; Tae Joo JEON ; Ji Young PARK ; Yong Ho JANG ; Deok Hee KIM ; Mi Jin RYU ; Dong Hyun SINN ; Tae Hoon OH
The Korean Journal of Gastroenterology 2013;62(6):375-378
Basaloid squamous cell carcinoma is a rare and aggressive variant of squamous cell carcinoma, which mostly occurs in the upper aerodigestive tracts. Basaloid squamous cell carcinoma also typically arises in the anal canal, but is extremely rare in the lower gastrointestinal tract. A 70-year-old man presented with loose stool and intermittent hematochezia 2 months ago. Colonoscopy showed an ulceroinfiltrative mass on the rectosigmoid colon from 16 cm to 18 cm above the anal verge. Conventional colonoscope could not pass through the lesion but it was possible with pediatric colonoscope. Abdominal CT scan showed 1.6 cm sized wall thickening with circumferential luminal narrowing in the rectosigmoid colon and multiple ill-defined low density masses in both lobes of the liver. Therefore, colon cancer with liver metastasis was suspected. However, basaloid cells were noted on histologic examination, and they were weakly positive for synaptophysin on immunohistochemical study. After palliative lower anterior resection, histologic examination of the resected specimen revealed basaloid differentiation with keratin pearls, and tumor cells were positively stained with high molecular weighted cytokeratin (34BE12) and CK 5/6. Thus, the patient was finally diagnosed with basaloid squamous cell carcinoma of rectosigmoid colon with distant metastases.
Aged
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Carcinoma, Squamous Cell/*diagnosis/pathology/surgery
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Colonoscopy
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Colorectal Neoplasms/*diagnosis/pathology/surgery
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Humans
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Immunohistochemistry
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Keratins/metabolism
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Liver Neoplasms/radiography/secondary
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Lung Neoplasms/radionuclide imaging/secondary
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Male
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Positron-Emission Tomography
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Synaptophysin/metabolism
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Tomography, X-Ray Computed
4.Diagnostic value of CT-guided extrapleural locating transthoracic automated cutting needle biopsy of lung lesions.
Yue-hua WEI ; Mei-yan LIAO ; Li-ying XU
Chinese Journal of Oncology 2011;33(6):473-475
Adenocarcinoma
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diagnosis
;
pathology
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Adolescent
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Adult
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Aged
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Aged, 80 and over
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Biopsy, Needle
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methods
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Carcinoma, Squamous Cell
;
diagnosis
;
pathology
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False Negative Reactions
;
Female
;
Granuloma
;
diagnosis
;
pathology
;
Humans
;
Lung Diseases
;
diagnosis
;
pathology
;
Lung Neoplasms
;
diagnosis
;
pathology
;
Male
;
Middle Aged
;
Radiography, Interventional
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Tomography, X-Ray Computed
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Tuberculosis, Pulmonary
;
diagnosis
;
pathology
;
Young Adult