1.Periampullary Carcinoma-A Rare Histopathological Variant
Fazl QP ; Mozzain IK ; Shakeel ur RK ; Mubashir AS ; Sajjad AD ; Abdul Rashid L ; Zubaida R
Journal of Surgical Academia 2015;5(2):36-39
Signet ring cell adenocarcinomas may be encountered in various parts of gastrointestinal tract but are almost unheard
of in the region of ampulla of vater. In the region of ampulla of vater even if we come across an adenocarcinoma, it
is usually a well differentiated variant. A 56-year-old female with features of obstructive jaundice on evaluation was
diagnosed to have a peri-ampullary carcinoma.The patient was subjected to a laparotomy. On exploration patient was
found to have a malrotation of gut. Patient was subjected to a pylorus preserving pancreatico-duodenectomy.
Histopathology of the resected specimen revealed a signet ring morphology which is a rare variant in periampullary
region.
Adenocarcinoma
;
Carcinoma, Signet Ring Cell
2.A Case of a Gastric Hyperplastic Polyp with a Signet Ring Cell Carcinoma.
Han Seung RYU ; Sae Ron SHIN ; Ki Hoon KIM ; Geom Seog SEO ; Suck Chei CHOI
Korean Journal of Gastrointestinal Endoscopy 2008;36(6):376-379
Gastric polyps can be categorized as hyperplastic or adenomatous. Hyperplastic gastric polyps account for 28~77% of gastric polyps. Adenomatous polyps are recommended for removal due to their premalignant potential. However, there is no consensus on treatment and endoscopic surveillance of hyperplastic gastric polyps. The incidence of malignant neoplasms found in hyperplastic polyps has been reported to be about 2.1%; most of the reported cases of hyperplastic gastric polyps with malignant transformation were histologically well differentiated. We report a rare case of a gastric hyperplastic polyp with a signet ring cell carcinoma, with a review of the literature.
Adenomatous Polyps
;
Carcinoma, Signet Ring Cell
;
Consensus
;
Incidence
;
Polyps
3.CT Finding of Signet Ring Cell Carcinoma of the Stomach.
Ki Nam LEE ; Jong Cheol CHOI ; Kyung Jin NAM ; Jae Ik KIM ; Byeung Ho PARK ; Duck Hwan JEUNG ; Seu Hee NA
Journal of the Korean Radiological Society 1994;30(2):325-330
PURPOSE: Signet-ring cell carcinoma is rather invasive and infiltrative than other histologic types of gastric cancer. We evaluated the characteristic CT findings of signet-ring cell carcinoma especially in the intensity and pattern of contrast enhancement. MATERIALS AND METHODS: We analyzed the CT findings of 22 cases with histologically proven signet-ring cell carcinoma, and compared them with those of 35 cases with histologically proven tubular adenocarcinoma. RESULTS: The double ring enhancement of the gastric mass was seen in 12 cases of signet-ring cell carcinoma and only one case of tubular adenocarcinoma. The masses of signet-ring cell carcinoma were enhanced more by the CT number of 10.2 than those of tubular adenocarcinoma. Of the masses of signet-ring cell carcinoma, those showed double ring enhancement were more intensely enhanced than those showed diffuse enhancement by the CT number of 22.9. CONCLUSION: We thought that neovascularity and different infiltration of the tumor cells in the gastric wall were responsible for the intense enhancement and double ring sign of signet-ring cell carcinoma. The possiblity of signet-ring cell carcinoma is high if a gastric mass show double ring sign and strong contrast enhancement.
Adenocarcinoma
;
Carcinoma, Signet Ring Cell*
;
Stomach Neoplasms
;
Stomach*
4.Signet Ring Cell Carcinoma Arising from a Solitary Juvenile Polyp in the Colon.
Hae Jung KIM ; Min Kwan KANG ; Hee Suk LEE ; Do Sun KIM ; Du Han LEE
Journal of the Korean Society of Coloproctology 2010;26(5):365-367
Juvenile polyps are relatively common polyps that affect predominantly young patients and may occur in isolated, multiple, and/or familial forms. They have been considered to be benign lesions without neoplastic potential, but for patients with multiple juvenile polyposis, the cumulative malignant risk is greater than fifty percents. In patients with a solitary polyp, the risks are minimal, and only a few cases of malignant change from a solitary juvenile polyp have been reported. We describe the case of a twenty one year old female with one solitary juvenile polyp, which contained a signet ring cell carcinoma in the mucosal layer.
Carcinoma, Signet Ring Cell
;
Colon
;
Colonic Polyps
;
Female
;
Humans
;
Polyps
5.Cytologic Features of Signet Ring Cell Carcinoma of the Uterine Cervix: A Report of Two Cases.
Hyun Yee CHO ; Seung Yeon HA ; Jaegul CHUNG ; Young Ha OH ; Dong Hae CHUNG ; Na Rae KIM ; Jong Min LEE ; Eui Don LEE
Korean Journal of Cytopathology 2003;14(2):66-70
Signet ring cell carcinoma is a rare type of mucinous adenocarcinoma of the uterine cervix. To the best of our knowledge, there is no report on cytologic findings of primary signet ring cell carcinoma of the uterine cervix in the literature. Recently, we experienced two cases of signet ring cell carcinoma of the uterine cervix. The finding of characteristic signet ring cells on cervicovaginal smear led to the diagnosis of signet ring cell carcinoma. However, primary signet ring cell carcinoma could not be cytologically distinguished from more common metastatic tumor. Therefore, diagnosis rests upon the recognition of signet ring cells and the absence of signet ring cell carcinoma elsewhere.
Adenocarcinoma, Mucinous
;
Carcinoma, Signet Ring Cell*
;
Cervix Uteri*
;
Diagnosis
;
Female
6.Radiologic findings of metastatic signet ring cell carcinoma to the breast from stomach.
Jin Young KWAK ; Eun Kyung KIM ; Ki Keun OH
Yonsei Medical Journal 2000;41(5):669-672
Two Korean women (41 and 23-years of age) presented with painful breast enlargement and redness. The involved breast was confirmed as metastatic signet ring cell carcinoma. Although metastatic signet ring cell carcinoma of the breast shows similar clinical symptoms to inflammatory breast cancer, the difference between the two is that this malignancy showed no microcalcifications or mass on radiographic findings (mammograms and US). Therefore, after the confirmation of signet ring cell carcinoma of the breast has been made, metastatic signet ring cell carcinoma should be considered if there are no microcalcifications or masses evident on radiographic findings.
Adult
;
Breast Neoplasms/secondary*
;
Breast Neoplasms/radiography*
;
Breast Neoplasms/pathology
;
Carcinoma, Signet Ring Cell/secondary*
;
Carcinoma, Signet Ring Cell/radiography*
;
Carcinoma, Signet Ring Cell/radiography*
;
Case Report
;
Female
;
Human
;
Stomach Neoplasms/pathology*
;
Tomography, X-Ray Computed
;
Ultrasonography
7.Understanding Growth Patterns of Signet Ring Cell Carcinoma of the Stomach Is Necessary for Successful Endoscopic Resection.
Gut and Liver 2015;9(6):695-696
No abstract available.
Carcinoma, Signet Ring Cell/*pathology/*surgery
;
Dissection/*methods
;
Female
;
*Gastroscopy
;
Humans
;
Male
;
Stomach Neoplasms/*pathology/*surgery
8.Clinical and Colonoscopic Characteristics of Primary Signet Ring Cell Carcinoma in Colorectum.
Sung Hee PYO ; Jeong Sik BYEON ; Seung Jae MYUNG ; Suk Kyun YANG ; Hyung Joon LEE ; Seung Il PYO ; Jin Ho KIM ; Jin Cheon KIM ; Se Jin JANG
Korean Journal of Gastrointestinal Endoscopy 2006;33(5):278-284
BACKGROUND/AIMS: A primary signet ring cell carcinoma (SRCC) in the colorectum is unusual. This study evaluated the clinical and colonoscopic characteristics of primary colorectal SRCC. METHODS: Twenty-eight patients diagnosed with a primary colorectal SRCC and 100 patients diagnosed with a primary colorectal nonmucinous adenocarcinoma were enrolled in this study. The medical records and colonoscopic findings were reviewed. RESULTS: The mean age was younger in the SRCC patients than in the nonmucinous adenocarcinoma patients (47.3+/-15.5 years vs. 60.3+/-10.4 years, p<0.001). In SRCC, hematochezia was less frequent while abdominal pain was more common (p<0.001). Duke stages A or B was rare in SRCC (4/28, 14.3% vs. 58/100, 58.0%, p<0.001). The colonoscopic features of Borrmann type 4 was more common in SRCC (10/28, 35.7% vs. 3/100, 3.0%, p<0.001). The occurrence of a tumor in the right colon was more frequent in SRCC (17/28, 60.7% vs. 20/100, 20.0%, p<0.001). The diagnostic yield of the first colonoscopic biopsy was lower in the SRCC patients (85.7% vs. 98.0%, p=0.021). CONCLUSIONS: Primary colorectal SRCC appears to occur in younger patients compared with nonmucinous adenocarcinoma. A more advanced stage and an infiltrative lesion such as Borrmann type 4 appears to be common and the diagnostic yield of a colonoscopic biopsy tends to be low in primary colorectal SRCC.
Abdominal Pain
;
Adenocarcinoma
;
Biopsy
;
Carcinoma, Signet Ring Cell*
;
Colon
;
Colonoscopy
;
Gastrointestinal Hemorrhage
;
Humans
;
Medical Records
9.Perforated Early Gastric Cancer: A case report.
Moon Soo LEE ; Sung Yong KIM ; Sang Hyun OH ; Man Kyu CHAE ; Il Kwon CHUNG ; Moo Jun BAEK ; Kyung Kyu PARK ; Chang Ho KIM ; Moo Sik CHO
Journal of the Korean Gastric Cancer Association 2001;1(1):64-67
An exceedingly rare case of perforated early gastric cancer is reported. A 68-year-old man developed peritonitis due to perforation of early gastric cancer. An emergency radical operation was performed and was followed by an uneventful recovery. Histologic examination of the surgical specimen showed type III early gastric cancer composed of a signet ring cell carcinoma. Five years after surgery, the patients was alive with no evidence of tumor recurrence. The rarity of this complication in early gastric cancer is discussed, and a review of the literature is presented.
Aged
;
Carcinoma, Signet Ring Cell
;
Emergencies
;
Humans
;
Peritonitis
;
Recurrence
;
Stomach Neoplasms*
10.Primary Signet Ring Cell Adenocarcinoma of the Prostate.
Yoon Hee LA ; Jong Yeon PARK ; Ho Seong SHIN ; Ki Shin SONG ; Kil Hyun OH ; Suk Sahn PARK
Korean Journal of Urology 1989;30(4):604-606
A 61-year old man visited to our hospital due to gross hematuria and voiding difficulty. Microscopic examination of the prostatic tissue revealed a tumor composed predominantly of signet ring cells. Signet ring cell adenocarcinoma of the prostate is extremely rare disease. Recently we have experienced a case of signet ring cell adenocarcinoma of the prostate and report it with brief review of literature.
Adenocarcinoma*
;
Carcinoma, Signet Ring Cell
;
Hematuria
;
Humans
;
Middle Aged
;
Prostate*
;
Rare Diseases