3.Diagnosis and treatment of primary ectopic thyroid carcinoma: report of 3 cases and literature review.
Yaqi ZHOU ; Minfei QIAN ; Zheng ZHOU ; Ting GONG ; Jiadong WANG
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2014;28(3):151-153
OBJECTIVE:
Discuss the clinical features of primary ectopic thyroid carcinoma.
METHOD:
The clinical data of three cases diagnosed of primary ectopic thyroid carcinoma in our department since 1990 were analyzed ret respectively and related literature was reviewed.
RESULT:
All three patients were young females that had cervical lumps before surgery. The pathology results confirmed the diagnosis of ectopic thyroid papillary carcinoma. All cases had followed up till now and no relapse signs occurred.
CONCLUSION
Ectopic thyroid tissue is resulting from developmental defects at early stages of thyroid gland embryogenesis. They can cancerization, the treatment of ectopic thyroid carcinoma is also controversial. Here,we report 3 cases of primary ectopic thyroid papillary carcinoma, all of which were removed by surgery, take thyroxin orally after surgery and have a great prognosis.
Adult
;
Carcinoma
;
diagnosis
;
therapy
;
Carcinoma, Papillary
;
Female
;
Humans
;
Thyroid Cancer, Papillary
;
Thyroid Neoplasms
;
diagnosis
;
therapy
6.Diagnosis and treatment of thyroid microcarcinoma.
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2014;28(24):1911-1917
Papillary thyroid microcarcinoma (PTMC) is defined as a papillary thyroid carcinoma measuring less than 10 mm in diameter. With the development of ultrasonic technology and the popularization of physical examination, the incidence of PTMC increased dramatically. Routine preoperative diagnostic methods include clinical examination, thyroid ultrasound and fine needle aspiration biopsy. But its treatment methods are still controversal. In this paper, we review literatures in recent years and discuss the clinical common problems of PTMC.
Biopsy, Fine-Needle
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Carcinoma
;
diagnosis
;
surgery
;
Carcinoma, Papillary
;
diagnosis
;
surgery
;
Humans
;
Incidence
;
Thyroid Cancer, Papillary
;
Thyroid Neoplasms
;
diagnosis
;
surgery
;
Thyroidectomy
7.CT Findings in the Differential Diagnosis of Benign and Malignant Thyroid Tumor.
Hye Weon JUNG ; Moon Hee HAN ; Hong Dae KIM ; Kee Hyun CHANG ; Heung Sik KANG ; Jung Gi IM
Journal of the Korean Radiological Society 1996;34(4):457-462
PURPOSE: We analysed CT findings of thyroid mass to determine the difference between a benign and a malignant mass and to evaluate the differential findings, if any. MATERIALS AND METHODS: The subjects were 87 cases with apathologically proven thyroid mass (malignancy in 66 cases, benign mass in 21 cases). CT findings were retrospectively analysed. For the primary masses, bilaterality, size, margin, attenuation of the mass, spotty portion with distinct high attenuation(which may suggest calcification), necrosis, cystic change, solid portion within the cyst, and invasion of adjacent structures were evaluated. For the lymph nodes, size, high attenuated spotty portion, necrosis, cystic change, and solid portion within the cyst were evaluated. CT findings of thyroid masses and lymph nodes were evaluated in order to determine whether these were benign or malignant. Statistical analysis was performed using the Mann-Whitney U-Wilcoxon rank sum test. RESULTS: In malignant masses, compared with benign, an indistinct margin of the mass(48% vs 19%), invasion of adjacent structures(53% vs 0%), and associated lymph node enlargement(50% vs 0%) were more frequent. With regard to bilaterality, size, attenuation, high-attenuated spotty portion(which may suggest calcification), necrosis, cystic change, and solid portion within the cyst, there was no significant difference between benign andmalignant masses. In masses of the former type, enlarged lymph node or invasion of adjacent structure were not seen at all. When the papillary solid portionwithin the cystic mass was additionally evaluated, papillany carcinoma was the most common finding(77% 14\18). CONCLUSION: General findings of malignancy such as margin, invasion of the mass, and lymph node enlargement are of help in the differential diagnosis of a malignant mass. High attenuated spotty portion, which may suggest calcification within the mass, or size of the mass are non-specific findings, and are not helpful in differential diagnosis. The papillary solid portion within the cyst of the mass could suggest papillary carcinoma as a first possibility and could be helpful in differential diagnosis.
Carcinoma, Papillary
;
Diagnosis, Differential*
;
Lymph Nodes
;
Necrosis
;
Thyroid Gland*
8.Papillary Cancer Arising in Remnant Thyroglossal Duct.
Sung Woo BAE ; Hyung Ho KIM ; Sang Soon KIM
Journal of the Korean Surgical Society 1999;56(Suppl):1038-1042
Remnant thyroglossal ducts are common developmental abnormalities of the thyroid gland. The malignant transformation of these structures is extremely rare. Even though a malignancy it is highly suspected in elderly patients with midline neck swelling, the diagnosis is seldom made preoperatively. In thyroglossal duct carcinomas, a papillary carcinoma is the most common pathologic finding. The etiology of such tumors is unclear, but a de novo origin and spread from primary thyroid-gland tumors has been suggested. There are different theories regarding the origin of and the therapy for these malignancies. This has important significance for therapeutic approaches. We report a case of a papillary cancer arising in a remnant thyroglossal duct which was managed by Sistrunk's operation and right thyroid lobectomy.
Aged
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Carcinoma, Papillary
;
Diagnosis
;
Humans
;
Neck
;
Thyroid Gland
9.A case of Primary Serous Papillary Carcinoma of the Peritoneum..
Moon Cheol PARK ; Jong Ho SHIN ; Jong Min LEE ; Young Yuk KIM ; Chan Yong PARK ; Sang Ik NAM ; Hyuni CHO
Korean Journal of Gynecologic Oncology and Colposcopy 1999;10(2):190-193
Although the peritoneum is rare site for a primary neoplasm, certain malignant neoplasms may arise from it. A case of 63-year-old woman who had a serous papillary carcinoma of peritoneal origin is reported. Extraovarian peritoneal serous papillary carcinoma was characterized by ascites, malignant washings, and omental involvement with bulky infiltration and/or multiple tumor nodules. The symptoms caused by diffuse spreading of the neoplasm over the peritoneum are the most important manifestation for clinical diagnosis of malignant primary neoplasm of peritoneum, especially serous papillary carcinoma. This behaving tumor was at least partially responded to therapy. In this report, we describe a case of serous papillary carcinoma of peritoneum carring on proper management with brief review.
Ascites
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Carcinoma, Papillary*
;
Diagnosis
;
Female
;
Humans
;
Middle Aged
;
Peritoneum*
10.Differential Diagnosis of a Follicular Carcinoma and Papillary Carcinoma of the Thyroid Gland Based on Sonographic Findings .
Kyung Sik YI ; Il Hun BAE ; Seung Young LEE ; Min Hee JEON
Journal of the Korean Society of Medical Ultrasound 2007;26(4):183-188
PURPOSE: The purpose of this study was to evaluate and compare the sonographic findings of a conventional papillary carcinoma, follicular carcinoma and a follicular variant of a papillary carcinoma. MATERIALS and METHODS: A total of 308 nodules from 231 patients that were diagnosed with a papillary carcinoma and a follicular carcinoma by surgery after sonography were analyzed. The nodules consisted of a conventional papillary carcinoma (255, 83%), a follicular variant of a papillary carcinoma (25, 8%), and a follicualar carcinoma (28, 9%). We compared and analyzed the sonographic findings of each nodule for content, margin, echotexture, shape, calcification and halo sign. RESULTS: A conventional papillary carcinoma showed significant different sonographic findings than a follicular carcinoma and a follicular variant of a papillary carcinoma for an ill-defined or well-defined spiculated margin (63.1%), marked hypoechogenicity (85.9%) and microcalcification (49%). A follicular carcinoma showed a significant difference than a conventional papillary carcinoma for a well-defined smooth margin (92.9%), iso, hypo- or hyperechogenicity (89.3%), wider than tall shape (100%) and halo sign (82.1%). The follicular variant of a papillary carcinoma showed similar findings to a follicular carcinoma except for marked hypoechogenicity (44%, p = 0.006) and taller than wide shape (16%, p = 0.027). CONCLUSION: The follicular carcinoma and follicular variant of a papillary carcinoma showed similar sonographic findings, but findings of a conventional papillary carcinoma were different.
Carcinoma, Papillary*
;
Diagnosis, Differential*
;
Humans
;
Thyroid Gland*
;
Ultrasonography*