1.Clinical evaluation of therapeutic trial for unresectable hepatocellular carcinoma.
Hung Jun KIM ; Hee Jung WANG ; Hyucksang LEE
Journal of the Korean Surgical Society 1991;40(5):601-610
No abstract available.
Carcinoma, Hepatocellular*
2.Radiofrequency Thermal Ablation of Hepatocellular Carcinoma.
Journal of the Korean Medical Association 2001;44(8):866-874
No abstract available.
Carcinoma, Hepatocellular*
3.Treatment of Hepatocellular carcinoma.
Korean Journal of Medicine 2001;61(6):583-589
No abstract available.
Carcinoma, Hepatocellular*
4.The Tissue Expression of HBsAg and HBcAg in Hepatocellular Carcinoma and Peritumoral Liver.
Jee Young HAN ; Woo Hee JUNG ; Chae Yoon CHON ; Chan Il PARK
Korean Journal of Pathology 1993;27(4):371-378
To evaluate the tissue expression rate and pattenr of HBsAg and HBcAg in tumors and peritumoral livers, an immunohistochemical study was undertaken on 47 surgically resected hepatocellular carcinomas(HCCs). The results are as follows. 1. Patient's sera were positive for HBsAg in 40 cases(85.1%). In the remaining 7 cases, the tumor and peritumoral liver expressed neither HBcAg nor HbSaG, suggesting that they were caused by other etiologies than hepatitis B virus. 2. The peritumoral liver had HBsAg and HBcAg in 95.0% and 27.5% among the 40 cases, respectively. But the tumor expressed HBsAg in 50.0% and HBcAg in none. 3. The expression of HBsAg within the tumor and both HBsAg and HBcAg in the peritumoral liver tended to be more frequent in the pretreated cases before surgery. 4. Edmondson-Steiner grade IV tumors revealed a lower expression rate of HBsAg than the low grade tumors(p<0.05). Incases with cirrhosis at peritumoral tissues, HBcAg was less frequently found than in those without cirrhosis. The majority of tissue HBsAg and HBcAg was represented as groups of positive cells. These results suggest that, during the development and progression of HCCs, the HBcAg containing cells are repeatedly removed and the HBcAg negative cells are selected, because cellular expression of HBcAg is the target of host immune response.
Carcinoma, Hepatocellular
5.Dynamic CT Finding of Pelioid HCC; Case Report.
Rak Chae SON ; Jae Woon KIM ; Jae Chun CHANG
Yeungnam University Journal of Medicine 2010;27(2):146-149
Pelioid hepatocellular carcinoma (HCC), a type of atypical HCC, is a rare histologic type of HCC. The radiologic findings of the pelioid HCC is differ from the typical type of HCC. To our knowledge, this case report is the second literature to show the enhancing features of a pelioid HCC on dynamic computed tomography (CT). Here we describe the dynamic CT findings in a case of surgically confirmed pelioid HCC.
Carcinoma, Hepatocellular
6.Acute Hydrothorax Due to HCC Involving Diaphragm during Peritoneal Dialysis.
Yong Sung AHN ; Jin KANG ; Moo Gon SONG ; Ki Tae PARK ; Tae Ik PARK ; Seung Jae AHN ; Sang Heon SONG ; Dong Won LEE ; Soo Bong LEE ; Ihm Soo KWAK
Korean Journal of Nephrology 2006;25(5):851-855
Massive hydrothorax is uncommon but well recognized complication of peritoneal dialysis. Possible mechanisms include a disorder of lymphatic drainage, pleuro-peritoneal pressure gradient, and congenital diaphragmatic defects. Hydrothorax in a CAPD patient caused by infiltrative disease or malignancy is very rare. Recently, two cases of hydrothorax in CAPD patients caused by systemic amyloidosis involving diaphragm were reported. However, no case of pleuro-peritoneal communication secondary to HCC infiltrating diaphragm was reported. This case was of a hydrothorax due to HCC in a CAPD patient. We performed video-assited thoracoscopic resection of diaphragmatic mass, diaphragmatic repair and thoracoscopic talc pleurodesis. This case showed that malignancy might be considered as a cause of a hydrothorax in a CAPD patient.
Carcinoma, Hepatocellular
7.Analysis of DNA Ploidy Pattern of Hepatocellular Carcinoma with Comparison between Flow Cytometric and Image Cytometric Study.
Sung Sook KIM ; Seok Gun PARK ; Dong Sun HAN ; Man Ha HUH
Korean Journal of Pathology 1992;26(1):1-9
Fifty cases of hepatocellularcarcinoma were studied using retrospective flow cytometric(FCM) and image cytometric(ICM) DNA analysis to determine the prevalence of aneuploid cell population and whether they were associated with any particular clinico-pathologic findings. At the same time, we compared the difference between FCM and ICM. The materials were prepared from 50 micrometer cut of paraffin embedded blocks. The DNA modal values, which could be defined in 42 cases by FCM with 74% aneuploidy and in 50 cases by ICM with 76% aneuploidy. So 95% of the cases had concordant DNA ploidy results by both techniques of FCM and ICM. Abnormal DNA pattern was correlated with age(<50), presence of cirrhosis, pathologic grade and some pathologic types(p<0.05), but was not correlated with presence of HBsAg, sex, alphafeto protein, and alcohol history(p>0.05). Also we found that ICM technique was easier to perform and interprete.
Carcinoma, Hepatocellular
8.Effect of transarterial chemoembolization in postoperative recurrent hepatocellular carcinoma.
Joon Koo HAN ; Jae Hyung PARK ; Ho Chul KIM ; Hyun Kyung LEE ; Byung Ihn CHOI ; Man Chung HAN ; Dong Young NOH ; Soo Tae KIM
Journal of the Korean Radiological Society 1991;27(4):453-457
No abstract available.
Carcinoma, Hepatocellular*
9.Analysis of therapeutic effects of transarterial chemoembolization in hepatocellular carcinoma.
Myung Sook LEE ; Eun Joo AN ; Eun Chul CHUNG ; Jung Soo SUH ; Chung Sik RHEE
Journal of the Korean Radiological Society 1991;27(4):447-452
No abstract available.
Carcinoma, Hepatocellular*
10.Application of Argyrophilic Nucleolar Organizer Regions(AgNORs) in the Diagnosi of Hepatocellular Carcinoma.
Cheol Hee YUN ; Sang Sook LEE ; Eun Sook CHANG
Korean Journal of Pathology 1993;27(6):553-560
Necleolar organizer regions(NORs) ARE LOOPS OF DNA which transcribe to ribosomal RNA by RNA polymerase I. Since NOR-associated proteins are argyrophilic, silver staining method has been used for demonstration of AgNORs. The numbers and/or configurations of NORs may reflect the activities of cells in hyperplastic and neoplastic conditions. To evaluated the applicability of AgNORs in the diagnosis of hepatocellular carcinoma, the author had performed silver staining on the routinely processed, formalin-fixed, paraffin-embedded sections of 14 cases of normal liver(control), 23 cirrhotic liver, and 21 hepatocellular carcinoma. The results are summarized as follows: 1) The mean number of AgNORs per nucleus(mAgNOR) of normal liver, cirrhotic liver and hepatocellular carcinoma was 1.45+/-0.07, 2.53+/-0.38 and 5.52+/-1.63, respectively. The difference of mAgNOR between normal and cirrhotic liver, and between cirrhotic liver and hepatocellular carcinoma was statistically significant, respectively(p<0.01). 2) The percentage of nuclei showing five or more AgNORs per nucleus(pAgNOR) was 0.07% in normal liver, 7.59% in cirrhotic liver, and 60.49% in hepatocellular carcinoma. 3) AgNORs in hepatocellular carcinoma were large, pleomorphic and irregularly clumped, in addition to increase of mAgNOR and high pAgNOR. In conclusion, the increase of mAgNOR, high pAgNOR and large, irregular AgNORs are regarded as an additional helpful finding for the histopathological diagnosis of hepatocellular carcinoma.
Carcinoma, Hepatocellular