A case of a woman aged 42 years old with abdomen pain under the navel and bilateral pelvis tumors indentified by CT scanner as post-peritoneal tumors and AFP level increased was treated at Viet Duc hospital with the diagnosis of embryonary carcinoma based on a mature malignant teratoma. Some aspects of the diagnosis and treatment of post-peritoneal teratoma with embryonary carcinoma were received. Authors concluded that up to now in adults for post peritoneal tumor under the group of germ cell tumors, the treatment of choice is a surgery of through removal of the tumor, then the formula of BEP, PEL or VAC chemiotherapy will be carried.
Carcinoma, Embryonal ; Teratoma ; Diagnosis ; Therapeutics

Primary germ cell tumor of extragonadal origin are rare, accounting for approximately 3 to 5 percent of all germ tumors. Extragonadal germ cell tumors usually originate in midline body structures. We report a case of extragonadal germ cell tumor from the left superficial inguinal area, a nonmidline structure and a case of from the superficial suprapubic area unusual site of extragonadal germ cell tumor-with brief of the literature.
Carcinoma, Embryonal* ; Germ Cells ; Neoplasms, Germ Cell and Embryonal

A case of a 20-year old Korean adolescent who had large (child-head sized) embryonal carcinoma of left testis was presented. Literature was also briefly reviewed.
Adolescent ; Carcinoma, Embryonal ; Humans ; Testis ; Young Adult

This case reports of nasopharyngeal embryonal rhabdomyosarcoma mainly for a stuffy nose, runny nose with blood, and without typical clinical manifestations. Electronic laryngoscopy tip: nasopharyngeal neoplasm. MRI tip: nasopharyngeal carcinoma. By pathological and immunohistochemical examinations, it finally was diagnosed with nasopharyngeal embryonal rhabdomyosarcoma.
Carcinoma ; Humans ; Nasopharyngeal Carcinoma ; Nasopharyngeal Neoplasms ; diagnosis ; Rhabdomyosarcoma, Embryonal ; diagnosis

Primary germ cell tumor of the testis is rare, which occupies 1 to 2% of all reported malignant male neoplasms. Combined primary germ cell tumor of the testis composed of embryonal carcinoma and seminoma is more rare tumor. The authors experienced a case of 50-year old male who presented with painless enlargement of right testicle. He has had radical orchiectomy and diagnosed by pathologically as combined germ cell tumor of testis. The testicle is measuring 180 gm in weight and 9×6×5 cm in dimension, and almostly replaced by tumor mass. Grossly the tumor is rubbery solid smooth tumor mass, with variegated cut surface with geographically outlined diffuse necrotic area. Histologically the tumor is composed of two components of tumor, which are solid growth pattern of large round to polyhedral cells with clear or granular cytoplasm and distinct cell border, and anastomosing glandular and papillary arrangement of anaplastic epithelial cells. The former corresponds to seminoma, and the latter to embryonal carcinoma. Each tumor lobule is separated by abundant fibrous stroma.
Carcinoma, Embryonal ; Cytoplasm ; Epithelial Cells ; Germ Cells* ; Humans ; Male ; Neoplasms, Germ Cell and Embryonal* ; Orchiectomy ; Seminoma ; Testis*

For evaluation on the histopathologic studies and age distribution of the testicular tumors in the Taegu area, the inguinal orchidectomized materials were collected at the Department of Pathology, College of Medicine, Yeungnam University, and the analyzed results were as follows: 1. In total of 11 cases of orchidectomized materials, germ cell tumors are 10 cases (90.9%). In germ cell tumors according to the histologic types, seminoma was 5 cases (45.5%), and embryonal carcinoma, 3 (27.2%). 2. The highest age incidence of the group is 20th and 30th, and the next, 50th and 10th.
Age Distribution ; Carcinoma, Embryonal ; Daegu* ; Incidence ; Neoplasms, Germ Cell and Embryonal ; Pathology ; Seminoma ; Testicular Neoplasms ; Testis*

Teratoma is one of germ cell tumor, common neoplasm in women of reproductive age, but it can arise at any age. Its malignant transformation is rare, less than 2%, frequently at older age. Nearly all the cases are squamous, sarcomatous and adenomatous transformation. Here we present a case of mixed transformation, adeno-squamous cell carcinoma with brief review of the concerned literature.
Carcinoma, Squamous Cell* ; Female ; Humans ; Neoplasms, Germ Cell and Embryonal ; Teratoma*

Mature cystic teratoma of the ovary is the most common ovarian germ cell tumor and almost benign, but malignant transformation occurs in less than 2% of benign mature teratoma. Of the malignancies arising in teratomas, squamous cell carcinoma is the most common (70-80%). The presentation in stage I disease dose not differ from that of benign cystic teratoma. In the early stage, the treatment is possible through surgical intervention alone. We experienced a case of squamous cell carcinoma of the ovary arising in mature cystic teratoma, which is presented with a brief review of literature.
Carcinoma, Squamous Cell* ; Female ; Neoplasms, Germ Cell and Embryonal ; Ovary* ; Teratoma*

A case of testicular embryonal carcinoma developed in s cryptorchid testis is presented with a review of the literature. According to Campbell's series, the incidence of malignant cryptorchid testis was 11.6%. and his statistical evaluation was similar to Gilbert and Hamilton's series of 7,000 cases of testicular neoplasms where 840 tumors were developed in undescended testes(12%). Both authors agree that the chance of neoplastic development in a cryptorchid testis is approximately 48 times greater then that developing in a normally descended testis. Several cases of testicular tumor were reported sporadically in Korea, but malignant tumors in cryptorchism were rarely seen in the literatures Only two cases of malignant cryptorchid testis were already reported in Korea.
Carcinoma, Embryonal* ; Cryptorchidism ; Incidence ; Korea ; Male ; Testicular Neoplasms ; Testis*

Primary germ cell tumors of the mediastinum are rare, accounting 1-5% among all germ cell tumors and 10% of all neoplasms in this area. Approximately 85% of these tumors occur in men with a mean age 29 years. These tumors are mainly found in the anterior mediastinum and appear grossly as large lobulated masses. They are frequently invasive at the time of diagnosis and almost 90% of patients are symptomatic. Primary nonseminomatous germ cell tumor arising in the posterior mediastinum is very rare. We report a case of 37- year old male arising from the posterior mediastinum. Serum tumors markers including alpha-fetoprotein and beta-hCG which are usually elevated in germ cell tumor were not elevated. He was found to have a primary mediastinal embryonal carcinoma with pulmonary metastasis at open exploration. He was treated with debulking surgery and cisplatin-based chemotherapy, died of sepsis after 15 months postoperatively.
alpha-Fetoproteins ; Carcinoma, Embryonal* ; Diagnosis ; Drug Therapy ; Humans ; Male ; Mediastinum* ; Neoplasm Metastasis ; Neoplasms, Germ Cell and Embryonal ; Sepsis