2.Feasibility of ultrasound-guided absorbable retaining thread needle localization for nonpalpable breast lesions
Seo Young PARK ; Hye Jung KIM ; Won Hwa KIM ; Hye Jin CHEON ; Hoseok LEE ; Ho Yong PARK ; Jin Hyang JUNG ; Ji Young PARK
Ultrasonography 2019;38(3):272-276
PURPOSE: Absorbable retaining thread (ART) needle localization utilizes a guiding needle with a thread; this technique was invented to reduce patient discomfort and wire migration. We investigated the feasibility of ultrasound (US)-guided ART needle localization for nonpalpable breast lesions. METHODS: ART needle localization was performed for 26 nonpalpable breast lesions in 26 patients who were scheduled to undergo surgical excision the day after localization. Seventeen breast lesions were initially diagnosed as invasive ductal carcinoma, six as ductal carcinomas in situ, and one as fibrocystic change. The other two cases without an initial pathologic diagnosis had suspicious US features, and excision was planned concomitantly with contralateral breast cancer surgery. The primary outcome was the technical success rate of ART needle localization confirmed by US immediately after the procedure, and the secondary outcomes were the percentage of clear margins on pathology and the complication rate of ART needle localization. RESULTS: The technical success rate of ART needle localization was 96.2% (25 of 26 patients), and the ART was located 1 cm away from the mass in one patient (3.8%). The lesions were successfully removed with clear margins in all 26 patients. No significant complications related to ART needle localization were observed. CONCLUSION: ART needle localization can be an alternative to wire needle localization for nonpalpable breast lesions.
Breast Neoplasms
;
Breast
;
Carcinoma, Ductal
;
Diagnosis
;
Humans
;
Needles
;
Pathology
;
Surgery, Computer-Assisted
;
Ultrasonography
3.Transformation of breast micropapillary ductal carcinoma in situ into invasive micropapillary carcinoma after recurrence in chest wall: report of a case.
Hong Lan ZHANG ; Cong Ying YANG ; Shun Qin LI ; Chun Fang ZHANG ; Yong Gang ZHAO ; Chang ZHANG ; Hao CHEN
Chinese Journal of Pathology 2023;52(2):175-177
4.Surgical margins assessment reduces re-excision rates in breast-conserving surgery.
Chang Yi WOON ; Serene Si Ning GOH ; Lin Seong SOH ; Chloe Fu Cui YEO ; Marc Weijie ONG ; Benjamin WONG ; Joelle Hoi Ting LEONG ; Jerry Tiong Thye GOO ; Clement Luck Khng CHIA
Annals of the Academy of Medicine, Singapore 2023;52(1):48-51
5.Treatment analysis of 26 patients with breast ductal carcinoma in situ.
Lan-bo ZHANG ; Yu-xiu XU ; Jian-li GENG ; Yu-hai ZHANG
Chinese Journal of Oncology 2003;25(2):195-197
OBJECTIVETo study the appropriate surgical treatment for breast ductal carcinoma in situ (DCIS).
METHODSTwenty-six such patients treated between 1992 and 2001 were retrospectively analyzed. Among them, 3 patients were treated by simple mastectomy, 23 patients by mastectomy and axillary lymph node dissection, 8 patients by chemotherapy and one patient by radiotherapy after operation. Median follow-up was 42 m (rang 12 - 112 m).
RESULTSExcept 3 of these 26 patients lost in follow-up and 1 patient died from diabetes mellitus, all the other 22 patients survived over 5 years. All lymph nodes dissected from 23 patients were negative. After surgery, 3 patients developed lymph edema of the arm.
CONCLUSIONDCIS, lacking the potential of metastasis, is not invasive. Conservative breast surgery without lymph node dissection is feasible for most DCIS patients.
Adult ; Aged ; Breast Neoplasms ; mortality ; pathology ; surgery ; Carcinoma in Situ ; mortality ; pathology ; surgery ; Carcinoma, Ductal, Breast ; mortality ; pathology ; surgery ; Female ; Humans ; Lymph Node Excision ; Mastectomy ; Middle Aged ; Retrospective Studies
8.Clinical application of MRI-guided puncture of breast microlesions.
Xin WANG ; Wenyan WANG ; Jie WANG ; Ying SONG ; Xiang WANG ; Feng YE
Chinese Journal of Oncology 2015;37(9):682-685
OBJECTIVETo explore the clinical indications of MRI-guided puncture positioning or biopsy, and evaluate the clinical practical value.
METHODSThe clinicopathological data of 30 patients who underwent MRI-guided puncture positioning or biopsy were retrospectively collected and analyzed, and the patients were followed up after operation.
RESULTSThe success rate of MRI-guided puncture was 100%. After biopsy or surgical resection, the pathological diagnoses were as follows: 6 cases (20.0%) of invasive carcinoma, 9 cases (30.0%) of ductal carcinoma in suit (DCIS), and 15 cases (50.0%) of benign lesions, and the false negative rate was 0.In the 30 patients, the lesions of 22 patients were not clear and difficult to analyze qualitatively by ultrasound or mammography imaging examination. After MRI-guided puncture positioning or biopsy, the pathological examination showed that 11 cases (50.0%) of them were malignant tumors. MRI examinations indicated as malignant in 21 cases, among them, seven cases were pathologically confirmed as benign pathology, with a false positive rate of 33.3%. MRI examination considered benign in 9 cases, in which one case was pathologically diagnosed as malignant, thus, the false negative rate was 11.1%.In the 30 patients, there were no hematoma, infection and other complications after the puncture. The median follow-up time was 7.5 months. One patient died due to breast cancer metastasis, one patient showed relapse by imaging examination and underwent surgery, one case was lost, and the remaining patients were normal in the regularly follow-up results.
CONCLUSIONSMRI-guided biopsy of breast microlesions is a safe, rapid and accurate diagnostic method. When the ultrasound and mammography can not find clear lesions or the lesions are difficult to analyze qualitatively, MRI-guided puncture positioning or biopsy can be applied to improve early diagnosis and treatment, and reduce false negative rate of breast cancer.
Biopsy ; methods ; Breast ; pathology ; Breast Neoplasms ; pathology ; surgery ; Carcinoma ; pathology ; surgery ; Carcinoma in Situ ; pathology ; surgery ; Carcinoma, Ductal, Breast ; pathology ; surgery ; Female ; Humans ; Magnetic Resonance Imaging, Interventional ; Mammography ; Punctures ; methods ; Retrospective Studies
9.Cystic hypersecretory carcinoma with microinvasive carcinoma and cystic hypersecretory hyperplasia of breast: report of a case.
Chinese Journal of Pathology 2010;39(1):54-55
Adenocarcinoma, Mucinous
;
pathology
;
Adult
;
Breast Neoplasms
;
metabolism
;
pathology
;
surgery
;
Carcinoma
;
pathology
;
Carcinoma in Situ
;
metabolism
;
pathology
;
surgery
;
Carcinoma, Ductal, Breast
;
metabolism
;
pathology
;
surgery
;
Diagnosis, Differential
;
Female
;
Fibrocystic Breast Disease
;
metabolism
;
pathology
;
surgery
;
Humans
;
Hyperplasia
;
Lactalbumin
;
metabolism
;
S100 Proteins
;
metabolism
10.A Case of Diode Laser Photocoagulation in the Treatment of Choroidal Metastasis of Breast Carcinoma.
Sang Joon LEE ; Soo Young KIM ; Shin Dong KIM
Korean Journal of Ophthalmology 2008;22(3):187-189
To report a single case of improvement on choroidal metastasis of breast cancer after laser photocoagulation. A 52-year-old female patient who complained of visual disturbance of the right eye with multiple states of metastasis of breast carcinoma. On initial examination, the right best-corrected visual acuity was 0.63. Right fundoscopy revealed an elevated mass-like lesion temporal to the macule with serous retinal detachment. The mass had a 3.5-disc diameter. A right fluorescein angiogram revealed hypofluorescence during the prearterial and arteriovenous phase and hyperfluorescence during the venous phase. The venous phase showed almost total masking of background choroidal fluorescence at the elevated lesion because of leakage and neovascularization. The patient was treated 4 times by diode laser photocoagulation in addition to chemotherapy. Fifty days after the diode laser treatments, the funduscopy examination and fluorescein angiogram revealed that the serous retinal detachment had been absorbed, the choroid had become flat, the lesion had been reduced in size and hyperfluorescence. The right best-corrected visual acuity was improved to 0.8. Laser photocoagulation appears not to cause any problems for the patient and may be an efficient treatment for patients with choroidal breast carcinoma.
Breast Neoplasms/pathology/*surgery
;
Carcinoma, Ductal, Breast/secondary/*surgery
;
Choroid Neoplasms/secondary/*surgery
;
Female
;
Fluorescein Angiography
;
Humans
;
Laser Coagulation/*methods
;
Lasers, Semiconductor/*therapeutic use
;
Middle Aged
;
Visual Acuity