1.Advances in cancer patients' supportive care needs
Chinese Journal of Practical Nursing 2014;30(33):4-7
This paper aimed to describe the concept of the cancerous person's supportive care needs and the current situation of the study on this issue abroad so that we can analyze the factors which influence the needs,and we also try to elaborate the shortcomings and study expectation on cancerous person's sup portive care study.
2.From Moral Experience to Care giving: the Theoretical and Practical Paths of Medical Humanities
Chinese Medical Ethics 2017;30(6):676-681
Most of the current medical humanities education focuses on the moral aspects without good theoreti-cal basis and specific practices on the medical institution and daily life.The article dates back to the origins of So-cial Science based on the concept caregiving put forward by the medical anthropologist Arthur Kleinman,and states that the ultimate purpose of Social Science is to make response to the social suffering and provide caregiving for it.Caregiving as moral experience is response to social suffering and attracts much importance,because it pro-vides both the theoretical basis and practical means for the current medical humanities education.Its characteristics of caregiving as moral experience to social suffering and caregiving as reciprocity meet the demands of current notion of Big health in China.
3.Jion - Up Community in Health Services
Chinese Medical Ethics 1994;0(06):-
Joint -Up Community is crucial to the community health services. Joint - Up is an kind of co -operation, but it is neither the co - operation of bureaucracy nor that of the market model. The new relationship of Joint - Up is based neither on responsibility nor on contract, but on equal partnership. It is vital to solve the ethical plight of health services in country.
4.Different effects of clozapine and risperidone on levels of blood glucose in patients with schizophrenia
Chinese Journal of Tissue Engineering Research 2001;5(23):144-145
Objective To investigate the different effects of clozapine and risperidone on levels of blood glucose in patients with schizophrenia. Method 200 qualified cases selected from psychiatric department were divided into two groups randomly, of which 100 cases accepted the treatment with clozapine and the other 100 cases with risperidone. Blood glucose tests were used before treatment ,4 weeks after treatment and 8 weeks after treatment Results There was significantly higher blood glucose level in clozapine- treated group than in risperidone- treated group after 4 or 8 weeks treatment. The number of cases who had elevated blood glucose level (>6.1 mmol/L) in clozapine- treated group was significantly more than in risperidone- treated group. Conclusion The glucoregulatory abnormality which leads to glucose elevation in clozapine- treated patients is greater than in risperidone- treated patients. Additional motivation to clinical monitor for antipsychotic treatment- related hyperglycemia is indicated.
5.Study on correlation between exposure dose and image quality of X-ray chest radiography
Yunxi CAO ; Xiaotao CAI ; Jindong XIE ; Xin CAO
Chinese Journal of Radiological Medicine and Protection 2014;34(3):225-227
Objective To investigate optimal radiation dose for digital radiography by researching the correlation between radiation dose and image quality of high kV chest radiography.Methods The kV of chest radiography was setted on 120 kV while mAs was changed.The chest radiography phantom and the contrast detail phantom CDRAD2.0 were exposed by DR with different mAs from 1 to 25 mAs.The entrance doses were measured for all exposures and the images were read independently by 5 observers on a higher resolution monitor of diagnosis work station.The image quality figure (IQF) was measured for each image.Comparison of the mean IQFs with different exposure doses were conducted in order to determined which was the optimal exposure condition for high kV radiography.The image quality of normal adult using different mAs,4 and 10 mAs for high KV chest radiography was compared.Results When the mAs was increased from 1 to 25 mAs,the entrance doses varied from 0.067 to 1.468 mGy.With the entrance doses increasing,the value of IQF was decreased (F =31.00,P < 0.05).The values of IQF were statistically different between 1 and 4 mAs(F =15.3,P <0.05),and between 10 and 25 mAs(F =9.74,P <0.05).At 4 and 10 mAs with the entrance dose 0.250 and 0.606 mGy,the synthesis score of chest high kV radiography from two kinds of exposure dose was (24.8 ± 1.64),(25.8 ± 2.05),with no statistically significant difference.Conclusions For digital radiography,increasing radiation dose can improve image information.The optimal entrance dose of high kV chest radiography for standard body was about 0.250 mGy.
7.Prevalence and risk factors of thyroid carcinoma
Lingzhi CAO ; Jianping XIE ; Xiaodong PENG
Journal of International Oncology 2014;41(4):267-270
The incidence of thyroid carcinoma is associated with a variety of factors.Radiation is the clear risk factor,the relationship between iodine intake and thyroid carcinoma remains controversial.Researches show that the genetic and epigenetic changes of many signaling pathways are the key of molecular pathogenetic mechanism of thyroid carcinoma.In addition,thyroid stimulating hormone,body mass index and chronic lymphocytic thyroiditis are also associated with thyroid carcinoma.
8.Therapeutic Effect Evaluation of Acupuncture and Chinese Patent Medicine on Rheumatoid Arthritis
Hongliang XIE ; Zhao SHI ; Xuemei CAO
Journal of Acupuncture and Tuina Science 2007;5(1):55-58
Objective: To evaluate the therapeutic effect of combining use of acupuncture and drugs on rheumatoid arthritis(RA) in the early and the active stages of by the imaging of bone and joint with 99m TC-methlene diphosphate(MDP). Methods: 102 cases of RA in the early and the active stages were randomly allocated into the compound Fengshining group (Group A),acupuncture group(Group B), and compound Fengshining plus acupuncture group(Group C).They were treated for 30 days. All patients were examined before treatment and after treatment by 99m TC-MDP imaging of the whole body, hands and feet, and analyzing method of random interested region was used to count the ratio of radioactivity in the affected area of RA to radioactivity in adjacent normal bone(T/TN). Meanwhile, joint swelling index, joint tenderness index, morning stiffness, gripping force, and erythrocyte sedimentation rate (ESR) were also observed. Results: T/TN of the Group A after treatments had no significant difference comparing with that before treatment(t = 1.35, P>0.05), while the Group B and C had significant differences(t = 5.31, t=8.97, P<0.01). The changes of clinical and experimental examination in the Group C had more significant differences than those in the Group A and B(P<0.05).Conclusion: Acupuncture therapy could promote RA recovery, and combining use of acupuncture and compound Fengshining had better effect.
9.Effects of Tongxinluo capsule on endodermis function and the expression of CD40, CD40L in artherosclerosis rabbits
Jiahuai CAO ; Xiongwei XIE ; Shuren MA
Chinese Journal of Primary Medicine and Pharmacy 2010;17(19):2605-2607
Objective To investigate the therapeutic effects of Tongxinluo and its influence on the expression of CD40 and CD40L in artherosclerosis rabbits. Methods 60 male rabbits were divided into three groups randomly,20 of each group: normal control group, model group and Tongxinluo group. The rabbits in model group and Tongxinluogroup were used to prepare the atherosclerosis model induced by high-cholesterol diet. The levels of ET-1, NOwere measurde. Before and 12 weeks after durg treatment,serum total cholesterol ,plaque areas and ratios of intima/media thickness were detected. The expression of CD40 and CD40L mRNA were determinated by quantitive RT-PCR. Results Serum total cholesterol level of Tongxinluo group was decreased compared with model group ( P < 0. 05 ), and they were both much higher than those of normal control group ( P < 0. 01 ); as compared with the model group, aortic plaque areas and ratios of intima/media thickness in Tongxinluo group reduced significantly [ (0.56 ± 0. 07) vs ( 1.16±0.08),P<0.01;(36.88±2.38)% vs (76.58 ±2.86) %,P <0. 0l] ;The expression of CD40 and CD40L mRNA also decreased in Tongxinluo group with statistic significance[ (0.798 ± 0.115 )、 (0. 592 ± 0. 132) vs (0.686±0. 132) 、(0.498 ±0. 108) ,P <0. 01 ) ]. Conclusion Tongxinluo had the ability to anti-artherosclerosis and its possible mechanism was down-regulate the expression of CD40 and CD40L.
10.Influence of alveolar ventilation changes on gastric intramucosal pH in neurosurgical patients
Xiaoying CAO ; Weirmin LIANG ; Zhi XIE
Chinese Journal of Anesthesiology 1996;0(07):-
Objective To assess the influence of changes in alveolar ventilation on gastro-intestinal perfusion measured via a nasogastric tonometer.Methods Sixteen ASA Ⅰ - Ⅱ patients ( 7 male, 9 female) aged 15-67 yr, undergoing elective intracranial operation were included in this study. The patients were premedicated with oral ranitidine 150 mg and intramuscular phenobarbital 0.1 g and atropine 0.5 mg. Anesthesia was induced with midazolam 1-2 mg, fentanyl 2 ?g? kg-1 , propofol 1.5-2.0 mg ? kg-1 and vecuronium 0.1 mg ? kg-1 , and maintained with 0.5%-2.0% isoflurane inhalation and intermittent iv boluses of fentanyl and vecuronium. The patients were intubated and mechanically ventilated after induction of anesthesia. The ventilatory settings were : RR 10 bpm; FGF 1 L? min-1; I: E = 1:2; the initial VT was 7 ml? kg-1 (T1 ) which was gradually increased to 8 ml ?kg-1(T2), 9ml?kg-1(T3) and 10 ml?kg-1 (T4) and then returned to 7 ml ? kg-1 again. Each VT was maintained for 1 h. A nasogastric tonometer (Tonocap, Datex-Ohmeda, Finland) was inserted into stomach and automatically measured gastric intramucosal CO2 tension (PgCO2) every 10 min. Radial artery was cannulated for direct MAP monitoring and blood sampling. Blood gas analysis was performed every hour at various VT levels. Gastric-to-arterial pH gap and gastric-to-arterial PCO2 gap [P(g-a)CO2] were calculated.Results PgCO2 decreased during T2_4 (hyperventilation phase) (P