Objective To investigate the application of white light emitting diode (LED) in magnetic resonance room, in order to resolve the damageable problem of incandescent lights under the high magnetic field. Methods The white LEDs and the incandescent lights were installed in MR room, the number of damaged lights was compared after 300 hours. Chi-square test was used for the statistical analysis. And the illuminance and 50 000 hours electricity consumption between LED and incandescent lights were calculated. Results The number of damaged LED and incandescent lights was 2 and 32, respectively and there was a significant difference (χ~2 =48.813 ,P =0.000). The illuminance of the LED and incandescent lights was 155 lx and 100 lX at the 0.75 m horizontal level and the 50 000 hours electricity consumption was 200 kW and 5000 kW, respectively. Conclusion It is feasible and a great advantage to use the white LEDs in MR room lighting.

Objective To study the expression and significance of nuclear factor-kappa B(NF-κB)and proliferating cell nuclear antigen(PCNA)in uterine cervix cancer tissues.Methods The expression of NF-κB p65 and PCNA in the uterine cervix cancer tissues(n=45)and normal cervix tissues(n=30)were detected by immunohisto chemistry method.Results The expression rate of NF-κB p65 and PCNA in the uterine cervix cancer tissues were significantly higher than that in normal cervix tissues(P＜0.05).The expression of NF-κB p65 and PCNA in stage Ⅰ b,Ⅱa were significantly higher than that in stageⅠ a(P＜0.05),they were significantly higher in poorly differentiated than those in moderately differentiated,well-differentiated(P ＜ 0.05),they were significantly higher in existing lymphnode metastasis than those in non-existing lymphnode metastasis(P ＜0.05);and the expression of NF-κB p65 was positively related to PCNA in uterine cervix cancer tissues(r=0.705,P＜0.05).Conclusion The invasion,infestation and metastasis maybe dosely related to NF-κB and PCNA.

Objective To investigate the efficacy and safety of tropisetron combined with sulpiride in treatment of chemotherapy-induced cisplatin program nausea and vomiting,so as to explore the effect to motilin and gastrin.Methods A total of 84 patients with chemotherapy-induced cisplatin program nausea and vomiting were divided into study group (44 cases) and control group (40 cases) by random digits table method,the patients in two groups were given tropisetron hydrochloride intravenous injection,and the study group was added sulpiride.The efficacy and side effects and effect to motilin and gastrin were observed.Results The fully control rate and efficient rate in acute nausea was 59.09％ (26/44),37.50％ (15/40),and 90.91％ (30/44),72.50％ (29/40) in study group and control group,and there was significant difference (P ＜ 0.05).The fully control rate and efficient rate in acute vomiting was 61.36 ％ (27/44),37.50％ (15/40),and 88.64％ (39/44),67.50％ (27/40) in study group and control group,and there was significant difference (P ＜0.05).The fully control rate and efficient rate in delayed nausea was 54.54％ (24/44),32.50％ (13/40),and 79.55％ (35/44),57.50％ (23/40) in study group and control group,and there was significant difference (P ＜ 0.05).The fully control rate and efficient rate in delayed vomiting was 45.45 ％ (20/44),22.50％ (9/40),and 75.00％ (33/44),52.50％ (21/40) in study group and control group,and there was significant difference (P＜ 0.05).The plasma motilin after treatment was lower than that before treatment in study group and control group[(308.35 ± 14.59) ng/L vs.(370.59 ± 15.72) ng/L and(341.87 ± 18.38) ng/L vs.(365.36 ± 23.72) ng/L],gastrin was higher than that before treatment in study group and control group [(206.97 ± 12.29) ng/L vs.(164.56 ± 14.17) ng/L and (171.58 ± 13.53) ng/L vs.(158.42 ± 17.29) ng/L],and there was significant difference (P ＜ 0.05).There was significant difference in the plasma motilin and gastrin after treatment between two groups (P ＜ 0.05).There was no significant difference in the occurrence of adverse drug reactions between two groups (P ＞ 0.05).Conclusion Tropisetron combined with sulpiride than the routine use of tropisetron can obtain the better the antiemetic effect.

Objective To observe the effect of Dachengqi granule on degree of illness, blood levels of inflammatory mediators, incidence rate and mortality of multiple organ dysfunction syndrome (MODS) so as to discuss its therapeutic mechanism on MODS. Methods A total of 51 patients with systemic inflammatory response syndrome in intensive care unit (ICU) were randomly divided into treatment group (n=26) and control group (n=25) for an observation of clinical manifestation and prognosis. The plasma levels of endotoxin, tumor necrosis factor-? (TNF-?), interleukin-1? (IL-1?), interleukin-4 (IL-4), interleukin-6 (IL-6), interleukin-10 (IL-10) and human leukocyte antigen DR (HLA-DR) of each patient were measured in order to determine the curative effect of Dachengqi granule. Results The plasma level of endotoxin in treatment group was ameliorated more significantly than that in the control group. Dachengqi granule could down-regulate the levels of proinflammatory mediators including TNF?, IL-1? and IL-6 and antiinflammatory mediators including IL-4 and IL-10 and up-regulate the expression of HLA-DR (P

Total gastrectomy is a very important mode of therapy for gastric cancer.Many different types of reconstruction have been proposed,but there is no definitive conclusions as to which procedure is the best because of the postoperative complications,such as dumping syndrome,regurgitant esophagitis,malnutrition and so on.In this review,the author summarized recent clinical studies addressing gastrointestinal reconstruction following total gastrectomy.There is still some debate on preserving duodenal passage and the pouch reconstruction can provide improvement of the quality of life in patients receiving total gastrectomy.

With the scientific and technological progress and rapid development of the social economy, the extensive application of various electronic equipments has gradually intensified the possibility of ELF-EMF(extreme low frequency electromagnetic fields) exposure, the relationship between ELF-EMF exposure and health effects attracted more and more eyes and many corresponding researches have been finished. In recent years, a lot of epidemiological researches about the relationship between ELF-EMF and leukemia, brain tumor, breast cancer and other tumors have been done at home and abroad, in the present paper the research results were reviewed and the possible mechanism of the effect of ELF-EMF exposure on tumors was discussed.

Intercellular adhesion molecule-1 (ICAM-1) is one of the major molecules in mediating the adhesion between leucocytes and endothelial cells. The article mainly elaborates the expression of ICAM-1 and its effect during cerebral ischemia; it also discusses the interaction between ICAM-1 and other inflammatory cytokines. Anti-ICAM-1 treatment is expected to become one of effective methods in the management of cerebral ischemic injury.

Leukoaraiosis is caused by a variety of diseases. It presents diffuse low density areas in periventricular and subcortical areas (centrum semiovale) on CT or presents diffuse high signals on T2-weighted imaging. Demyelination of white matter fibers caused by arteriopathy is one of the major causes of leukoaraiosis. This article reviews the clinical manifestation, imaging and pathological features of leukoaraiosis, as well as its pathogenesis.

Objective:To explore the influence of granulocyte-colony stimulating factor(G-CSF) combined with adrenocortical steroid and/or immunosuppressants on immune system of donor mice during hematopoietic stem cell mobilization.Methods: The donor C57BL/6 mice were divided into 4 groups according to the mobilization strategies,namely,the G-CSF group((250 ?g/kg) for 4 days),G-CSF(250 ?g/kg for 4 days) + methylprednisolone group(100 mg/kg on day 3),G-CSF((250 ?g/kg) for 4 days) + methylprednisolone group(100 mg/kg on day 3) + cyclosporine A(100 mg/kg on day 3),and PBS control group.The post-mobilization T lymphocytes of C57BL/6 mice and the splenocytes of BALB/c mice were subjected to mixed lymphocyte reactions(MLR).The levels of IFN-?,IL-4,and TGF-?_(1) were determined in the supernatants of donor mice splenocytes by ELISA method and the mRNA levels of IFN-? and IL-4 were determined by RT-PCR.Results: The results showed that the MLR-inhibitory activities in the 3(G-CSF) mobilized groups were 42%,21%, and 39%,respectively;all lower than that in PBS control group(68%).IFN-? levels in the 3 G-CSF mobilized groups were lower than that in PBS control group,but he levels of IL-4 and TGF-?_(1)were significantly higher than those in PBS group(P

Objective To determine if the fibrinogen/C reactive protein (CRP) ratio could be used in sepsis patients as a predictor for disseminated intravascular coagulation.Methods A total of 61 patients with sepsis admitted to emergency intensive care unit (EICU) were enrolled.C reactive protein (CRP) and variables of coagulation such as Platelet (PLT),prothrombin time (PT),activated partial thrombopastin time (APTT),fibrinogen and D-dimer were analyzed during 24 hours after admission to EICU.APACHE Ⅱ score,ISTH score and JAAM score were evaluated.According to DIC score (JAAM score and ISTH score),the patients were divided into two groups:overt DIC and no overt DIC.Data were expressed in mean ±standard deviation and were statistically analyzed by SPSS 17.0.The differences of CRP,PLT,PT,APTT,fibrinogen and D-dimer of patients in each group were analyzed by independent samples t test.The receiver-operating characteristics (ROC) analysis was performed to predict the diagnostic power of the variables fibrinogen,CRP,and fibrinogen/C reactive protein (CRP) ratio.In addition,the odds ratios (OR) were estimated by chi-square test and the 95％ confidence intervals were calculated.Results In overt DIC group fibrinogen/C reactive protein (CRP) ratio was significantly lower.The receiver-operating characteristic analysis showed for the fibrinogen/C reactive protein (CRP) ratio (area under the curve:ISTH criteria 0.691 and JAAM criteria 0.814) significantly better discriminative power than for fibrinogen (area under the curve:ISTH criteria 0.608 and JAAM criteria 0.429) and CRP (area under the curve:ISTH criteria 0.561 and JAAM criteria 0.788).The odds ratio for fibrinogen/C reactive protein (CRP) ratio (＜ 45) was 11.14 and CRP (＞ 70 mg/L) was 8.05.Conclusions We suggest that the fibrinogen/C reactive protein (CRP)ratio could be a diagnostic factor for the occurrence of disseminated intravascular coagulation in sepsis patients.