1.Influence of heating rate on the flexural strength of monolithic zirconia
The Journal of Advanced Prosthodontics 2019;11(4):202-208
PURPOSE: Fabrication of zirconia restorations with ideal mechanical properties in a short period is a great challenge for clinicians. The purpose of the study was to investigate the effect of heating rate on the mechanical and microstructural properties of monolithic zirconia. MATERIALS AND METHODS: Forty monolithic zirconia specimens were prepared from presintered monolithic zirconia blanks. All specimens were then assigned to 4 groups according to heating rate as Control, Group 15℃, Group 20℃, and Group 40℃. All groups were sintered according to heating rates with the sintering temperature of 1500℃, a holding time of 90 minutes and natural cooling. The phase composition was examined by XRD analysis, three-point bending test was conducted to examine the flexural strength, and Weibull analysis was conducted to determine weibull modulus and characteristic strength. Average grain sizes were determined by SEM analysis. One-way ANOVA test was performed at a significance level of 0.05. RESULTS: Only tetragonal phase characteristic peaks were determined on the surface of analyzed specimens. Differences among the average grain sizes of the groups were not statistically significant. The results of the three-point bending test revealed no significant differences among the flexural strength of the groups (P>.05). Weibull modulus of groups was ranging from 3.50 to 4.74. The highest and the lowest characteristic strength values were obtained in Group 20℃ and Control Group, respectively. CONCLUSION: Heating rate has no significant effect on the flexural strength of monolithic zirconia. Monolithic zirconia restorations can be produced in shorter sintering periods without affecting the flexural strength by modifying the heating rate.
Heating
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Hot Temperature
2.The effects of different lighting conditions on the accuracy of intraoral scanning
Mehmet KARAKUZU ; Caner ÖZTÜRK ; Züleyha Başar KARAKUZU ; Mustafa ZORTUK
The Journal of Advanced Prosthodontics 2024;16(5):311-318
PURPOSE:
This study aimed to investigate the extent to which intraoral scanning are affected by clinical conditions, and whether ambient lighting and different color temperatures have an impact on the accuracy of intraoral scanner, as well as to evaluate scanning time.
MATERIALS AND METHODS:
Twelve different environments were created using various ambient lighting conditions (0, 500, 1000 and 1500 lux) and color temperatures (white, blue and yellow). A partially edentulous mandibular model with two implants and a three-unit bridge was scanned under each environment until 10 digital models were obtained, and scanning times were recorded using a virtual stopwatch. A 3D analysis was performed on the obtained digital models, and the data were analyzed using a software. The generalized linear model analysis and Tukey multiple comparison test were used to analyse the data (P < .05).
RESULTS:
The effect of lux, color temperature, and scanning times on RMS data was found to be significant (P < .001). The mean RMS value was the highest in the 0 lux group and the lowest in the 500 lux group. Regarding the color temperature, the highest RMS value was in the white color group and the lowest in the yellow color group. Scanning times were similar among the 0, 500 and 1000 lux groups, with a significant increase in the 1500 lux group.
CONCLUSION
Different ambient lighting conditions and color temperatures have significant effect on the accuracy of intraoral scanning.
3.The effects of different lighting conditions on the accuracy of intraoral scanning
Mehmet KARAKUZU ; Caner ÖZTÜRK ; Züleyha Başar KARAKUZU ; Mustafa ZORTUK
The Journal of Advanced Prosthodontics 2024;16(5):311-318
PURPOSE:
This study aimed to investigate the extent to which intraoral scanning are affected by clinical conditions, and whether ambient lighting and different color temperatures have an impact on the accuracy of intraoral scanner, as well as to evaluate scanning time.
MATERIALS AND METHODS:
Twelve different environments were created using various ambient lighting conditions (0, 500, 1000 and 1500 lux) and color temperatures (white, blue and yellow). A partially edentulous mandibular model with two implants and a three-unit bridge was scanned under each environment until 10 digital models were obtained, and scanning times were recorded using a virtual stopwatch. A 3D analysis was performed on the obtained digital models, and the data were analyzed using a software. The generalized linear model analysis and Tukey multiple comparison test were used to analyse the data (P < .05).
RESULTS:
The effect of lux, color temperature, and scanning times on RMS data was found to be significant (P < .001). The mean RMS value was the highest in the 0 lux group and the lowest in the 500 lux group. Regarding the color temperature, the highest RMS value was in the white color group and the lowest in the yellow color group. Scanning times were similar among the 0, 500 and 1000 lux groups, with a significant increase in the 1500 lux group.
CONCLUSION
Different ambient lighting conditions and color temperatures have significant effect on the accuracy of intraoral scanning.
4.The effects of different lighting conditions on the accuracy of intraoral scanning
Mehmet KARAKUZU ; Caner ÖZTÜRK ; Züleyha Başar KARAKUZU ; Mustafa ZORTUK
The Journal of Advanced Prosthodontics 2024;16(5):311-318
PURPOSE:
This study aimed to investigate the extent to which intraoral scanning are affected by clinical conditions, and whether ambient lighting and different color temperatures have an impact on the accuracy of intraoral scanner, as well as to evaluate scanning time.
MATERIALS AND METHODS:
Twelve different environments were created using various ambient lighting conditions (0, 500, 1000 and 1500 lux) and color temperatures (white, blue and yellow). A partially edentulous mandibular model with two implants and a three-unit bridge was scanned under each environment until 10 digital models were obtained, and scanning times were recorded using a virtual stopwatch. A 3D analysis was performed on the obtained digital models, and the data were analyzed using a software. The generalized linear model analysis and Tukey multiple comparison test were used to analyse the data (P < .05).
RESULTS:
The effect of lux, color temperature, and scanning times on RMS data was found to be significant (P < .001). The mean RMS value was the highest in the 0 lux group and the lowest in the 500 lux group. Regarding the color temperature, the highest RMS value was in the white color group and the lowest in the yellow color group. Scanning times were similar among the 0, 500 and 1000 lux groups, with a significant increase in the 1500 lux group.
CONCLUSION
Different ambient lighting conditions and color temperatures have significant effect on the accuracy of intraoral scanning.
5.The effects of different lighting conditions on the accuracy of intraoral scanning
Mehmet KARAKUZU ; Caner ÖZTÜRK ; Züleyha Başar KARAKUZU ; Mustafa ZORTUK
The Journal of Advanced Prosthodontics 2024;16(5):311-318
PURPOSE:
This study aimed to investigate the extent to which intraoral scanning are affected by clinical conditions, and whether ambient lighting and different color temperatures have an impact on the accuracy of intraoral scanner, as well as to evaluate scanning time.
MATERIALS AND METHODS:
Twelve different environments were created using various ambient lighting conditions (0, 500, 1000 and 1500 lux) and color temperatures (white, blue and yellow). A partially edentulous mandibular model with two implants and a three-unit bridge was scanned under each environment until 10 digital models were obtained, and scanning times were recorded using a virtual stopwatch. A 3D analysis was performed on the obtained digital models, and the data were analyzed using a software. The generalized linear model analysis and Tukey multiple comparison test were used to analyse the data (P < .05).
RESULTS:
The effect of lux, color temperature, and scanning times on RMS data was found to be significant (P < .001). The mean RMS value was the highest in the 0 lux group and the lowest in the 500 lux group. Regarding the color temperature, the highest RMS value was in the white color group and the lowest in the yellow color group. Scanning times were similar among the 0, 500 and 1000 lux groups, with a significant increase in the 1500 lux group.
CONCLUSION
Different ambient lighting conditions and color temperatures have significant effect on the accuracy of intraoral scanning.
6.The effects of different lighting conditions on the accuracy of intraoral scanning
Mehmet KARAKUZU ; Caner ÖZTÜRK ; Züleyha Başar KARAKUZU ; Mustafa ZORTUK
The Journal of Advanced Prosthodontics 2024;16(5):311-318
PURPOSE:
This study aimed to investigate the extent to which intraoral scanning are affected by clinical conditions, and whether ambient lighting and different color temperatures have an impact on the accuracy of intraoral scanner, as well as to evaluate scanning time.
MATERIALS AND METHODS:
Twelve different environments were created using various ambient lighting conditions (0, 500, 1000 and 1500 lux) and color temperatures (white, blue and yellow). A partially edentulous mandibular model with two implants and a three-unit bridge was scanned under each environment until 10 digital models were obtained, and scanning times were recorded using a virtual stopwatch. A 3D analysis was performed on the obtained digital models, and the data were analyzed using a software. The generalized linear model analysis and Tukey multiple comparison test were used to analyse the data (P < .05).
RESULTS:
The effect of lux, color temperature, and scanning times on RMS data was found to be significant (P < .001). The mean RMS value was the highest in the 0 lux group and the lowest in the 500 lux group. Regarding the color temperature, the highest RMS value was in the white color group and the lowest in the yellow color group. Scanning times were similar among the 0, 500 and 1000 lux groups, with a significant increase in the 1500 lux group.
CONCLUSION
Different ambient lighting conditions and color temperatures have significant effect on the accuracy of intraoral scanning.
7.Prognostic factors of adult granulosa cell tumors of the ovary: a Turkish retrospective multicenter study
Okan OKTAR ; Vakkas KORKMAZ ; Alp TOKALIOĞLU ; Çağatayhan ÖZTÜRK ; Özgür ERDOĞAN ; Yeşim UÇAR ; Hande Esra KOCA YILDIRIM ; Candost HANEDAN ; Fatih KILIÇ ; Burak ERSAK ; Necim YALÇIN ; Fatma ÖZMEN ; Alper KAHRAMAN ; Selin Aktürk ESEN ; Sevda BAŞ ; Emel Doğan ÖZDAŞ ; İlker SELÇUK ; Gökhan UÇAR ; Özgür KOÇAK ; Caner ÇAKIR ; Sevgi KOÇ ; Çiğdem KILIÇ ; Günsu Kimyon CÖMERT ; Işın ÜREYEN ; Tayfun TOPTAŞ ; Mehmet Ali NARIN ; Tolga TAŞÇI ; Salih TAŞKIN ; Nurettin BORAN ; Muzaffer SANCI ; Fahriye Tuğba KÖŞ ; Özlem Moraloğlu TEKIN ; Yaprak Engin ÜSTÜN ; Fırat ORTAÇ ; Taner TURAN
Journal of Gynecologic Oncology 2024;35(3):e39-
Objective:
To define the clinical, histopathological features and the prognostic factors affecting survival in patients with adult granulosa cell tumors of the ovary (AGCT).
Methods:
A 322 patients whose final pathologic outcome was AGCT treated at nine tertiary oncology centers between 1988 and 2021 participated in the study.
Results:
The mean age of the patients was 51.3±11.8 years and ranged from 21 to 82 years.According to the International Federation of Gynecology and Obstetrics 2014, 250 (77.6%) patients were stage I, 24 (7.5%) patients were stage II, 20 (6.2%) patients were stage III, and 3 (7.8%) were stage IV. Lymphadenectomy was added to the surgical procedure in 210(65.2%) patients. Lymph node involvement was noted in seven (3.3%) patients. Peritoneal cytology was positive in 19 (5.9%) patients, and 13 (4%) had metastases in the omentum. Of 285 patients who underwent hysterectomy, 19 (6.7%) had complex hyperplasia with atypia/ endometrial intraepithelial neoplasia, and 8 (2.8%) had grade 1 endometrioid endometrial carcinoma. It was found that 93 (28.9%) patients in the study group received adjuvant treatment. Bleomycin, etoposide, cisplatin was the most commonly used chemotherapy protocol. The median follow-up time of the study group was 41 months (range, 1–276months). It was noted that 34 (10.6%) patients relapsed during this period, and 9 (2.8%)patients died because of the disease. The entire cohort had a 5-year disease-free survival (DFS) of 86% and a 5-year disease-specific survival of 98%. Recurrences were observed only in the pelvis in 13 patients and the extra-abdominal region in 7 patients. The recurrence rate increased 6.168-fold in patients with positive peritoneal cytology (95% confidence interval [CI]=1.914–19.878; p=0.002), 3.755-fold in stage II–IV (95% CI=1.275–11.063; p=0.016), and 2.517-fold in postmenopausal women (95% CI=1.017–6.233; p=0.046) increased.
Conclusion
In this study, lymph node involvement was detected in 3.3% of patients with AGCT. Therefore, it was concluded that lymphadenectomy can be avoided in primary surgical treatment. Positive peritoneal cytology, stage, and menopausal status were independent prognostic predictors of DFS.
8.Prognostic factors of adult granulosa cell tumors of the ovary: a Turkish retrospective multicenter study
Okan OKTAR ; Vakkas KORKMAZ ; Alp TOKALIOĞLU ; Çağatayhan ÖZTÜRK ; Özgür ERDOĞAN ; Yeşim UÇAR ; Hande Esra KOCA YILDIRIM ; Candost HANEDAN ; Fatih KILIÇ ; Burak ERSAK ; Necim YALÇIN ; Fatma ÖZMEN ; Alper KAHRAMAN ; Selin Aktürk ESEN ; Sevda BAŞ ; Emel Doğan ÖZDAŞ ; İlker SELÇUK ; Gökhan UÇAR ; Özgür KOÇAK ; Caner ÇAKIR ; Sevgi KOÇ ; Çiğdem KILIÇ ; Günsu Kimyon CÖMERT ; Işın ÜREYEN ; Tayfun TOPTAŞ ; Mehmet Ali NARIN ; Tolga TAŞÇI ; Salih TAŞKIN ; Nurettin BORAN ; Muzaffer SANCI ; Fahriye Tuğba KÖŞ ; Özlem Moraloğlu TEKIN ; Yaprak Engin ÜSTÜN ; Fırat ORTAÇ ; Taner TURAN
Journal of Gynecologic Oncology 2024;35(3):e39-
Objective:
To define the clinical, histopathological features and the prognostic factors affecting survival in patients with adult granulosa cell tumors of the ovary (AGCT).
Methods:
A 322 patients whose final pathologic outcome was AGCT treated at nine tertiary oncology centers between 1988 and 2021 participated in the study.
Results:
The mean age of the patients was 51.3±11.8 years and ranged from 21 to 82 years.According to the International Federation of Gynecology and Obstetrics 2014, 250 (77.6%) patients were stage I, 24 (7.5%) patients were stage II, 20 (6.2%) patients were stage III, and 3 (7.8%) were stage IV. Lymphadenectomy was added to the surgical procedure in 210(65.2%) patients. Lymph node involvement was noted in seven (3.3%) patients. Peritoneal cytology was positive in 19 (5.9%) patients, and 13 (4%) had metastases in the omentum. Of 285 patients who underwent hysterectomy, 19 (6.7%) had complex hyperplasia with atypia/ endometrial intraepithelial neoplasia, and 8 (2.8%) had grade 1 endometrioid endometrial carcinoma. It was found that 93 (28.9%) patients in the study group received adjuvant treatment. Bleomycin, etoposide, cisplatin was the most commonly used chemotherapy protocol. The median follow-up time of the study group was 41 months (range, 1–276months). It was noted that 34 (10.6%) patients relapsed during this period, and 9 (2.8%)patients died because of the disease. The entire cohort had a 5-year disease-free survival (DFS) of 86% and a 5-year disease-specific survival of 98%. Recurrences were observed only in the pelvis in 13 patients and the extra-abdominal region in 7 patients. The recurrence rate increased 6.168-fold in patients with positive peritoneal cytology (95% confidence interval [CI]=1.914–19.878; p=0.002), 3.755-fold in stage II–IV (95% CI=1.275–11.063; p=0.016), and 2.517-fold in postmenopausal women (95% CI=1.017–6.233; p=0.046) increased.
Conclusion
In this study, lymph node involvement was detected in 3.3% of patients with AGCT. Therefore, it was concluded that lymphadenectomy can be avoided in primary surgical treatment. Positive peritoneal cytology, stage, and menopausal status were independent prognostic predictors of DFS.
9.Prognostic factors of adult granulosa cell tumors of the ovary: a Turkish retrospective multicenter study
Okan OKTAR ; Vakkas KORKMAZ ; Alp TOKALIOĞLU ; Çağatayhan ÖZTÜRK ; Özgür ERDOĞAN ; Yeşim UÇAR ; Hande Esra KOCA YILDIRIM ; Candost HANEDAN ; Fatih KILIÇ ; Burak ERSAK ; Necim YALÇIN ; Fatma ÖZMEN ; Alper KAHRAMAN ; Selin Aktürk ESEN ; Sevda BAŞ ; Emel Doğan ÖZDAŞ ; İlker SELÇUK ; Gökhan UÇAR ; Özgür KOÇAK ; Caner ÇAKIR ; Sevgi KOÇ ; Çiğdem KILIÇ ; Günsu Kimyon CÖMERT ; Işın ÜREYEN ; Tayfun TOPTAŞ ; Mehmet Ali NARIN ; Tolga TAŞÇI ; Salih TAŞKIN ; Nurettin BORAN ; Muzaffer SANCI ; Fahriye Tuğba KÖŞ ; Özlem Moraloğlu TEKIN ; Yaprak Engin ÜSTÜN ; Fırat ORTAÇ ; Taner TURAN
Journal of Gynecologic Oncology 2024;35(3):e39-
Objective:
To define the clinical, histopathological features and the prognostic factors affecting survival in patients with adult granulosa cell tumors of the ovary (AGCT).
Methods:
A 322 patients whose final pathologic outcome was AGCT treated at nine tertiary oncology centers between 1988 and 2021 participated in the study.
Results:
The mean age of the patients was 51.3±11.8 years and ranged from 21 to 82 years.According to the International Federation of Gynecology and Obstetrics 2014, 250 (77.6%) patients were stage I, 24 (7.5%) patients were stage II, 20 (6.2%) patients were stage III, and 3 (7.8%) were stage IV. Lymphadenectomy was added to the surgical procedure in 210(65.2%) patients. Lymph node involvement was noted in seven (3.3%) patients. Peritoneal cytology was positive in 19 (5.9%) patients, and 13 (4%) had metastases in the omentum. Of 285 patients who underwent hysterectomy, 19 (6.7%) had complex hyperplasia with atypia/ endometrial intraepithelial neoplasia, and 8 (2.8%) had grade 1 endometrioid endometrial carcinoma. It was found that 93 (28.9%) patients in the study group received adjuvant treatment. Bleomycin, etoposide, cisplatin was the most commonly used chemotherapy protocol. The median follow-up time of the study group was 41 months (range, 1–276months). It was noted that 34 (10.6%) patients relapsed during this period, and 9 (2.8%)patients died because of the disease. The entire cohort had a 5-year disease-free survival (DFS) of 86% and a 5-year disease-specific survival of 98%. Recurrences were observed only in the pelvis in 13 patients and the extra-abdominal region in 7 patients. The recurrence rate increased 6.168-fold in patients with positive peritoneal cytology (95% confidence interval [CI]=1.914–19.878; p=0.002), 3.755-fold in stage II–IV (95% CI=1.275–11.063; p=0.016), and 2.517-fold in postmenopausal women (95% CI=1.017–6.233; p=0.046) increased.
Conclusion
In this study, lymph node involvement was detected in 3.3% of patients with AGCT. Therefore, it was concluded that lymphadenectomy can be avoided in primary surgical treatment. Positive peritoneal cytology, stage, and menopausal status were independent prognostic predictors of DFS.