1.A Campylobacteriosis Outbreak Caused by One Asymptomatic Food Handler Carrier.
Ai Xia YAN ; Gui Lan ZHOU ; Peng GAO ; Ying KANG ; Shou Fei LI ; Yuan Yuan WANG ; Feng Shuang WANG ; Hai Rui WANG ; Ying LI ; Mao Jun ZHANG
Biomedical and Environmental Sciences 2023;36(8):779-782
In August 2021, three students with diarrhea from the same school visited a local hospital in the S district of Beijing. An epidemic investigation showed that there were more students with diarrhea in the same school and they had one meal together. Campylobacter jejuni was isolated from both patients with diarrhea and asymptomatic food handlers; however, the latter also carried Campylobacter coli. Phylogenomic analysis showed that there was a campylobacteriosis outbreak among the students, and the asymptomatic food handler may have been the source of the infection. Routine inspection and surveillance for Campylobacter is needed for the food producing staff, particularly those cooking in the cafeteria in schools or other public food services.
Humans
;
Campylobacter Infections/epidemiology*
;
Gastroenteritis
;
Diarrhea
;
Campylobacter
;
Disease Outbreaks
4.Two Cases of Campylobacter fetus Septicemia.
Yunsop CHONG ; Yoon Chung KIM ; Samuel Y LEE ; Young Myoung MOON
Yonsei Medical Journal 1979;20(1):56-60
Campylobacter fetus subsp. intestinalis was isolated from the blood of two different patients. One patient was a 46-year-old male with liver cirrhosis and the other a 44-year-old male with co1on carcinoma. These are the second and third documented infections of this kind in Korea. Difficulties of their isolation were well illustrated. For instance, the growth was detected after a long incubation of 4 to 6 days. All of the 3 blood cultures from the carcinoma patient, but on1y 2 of 3 specimens from the other patient, yielded the organism.
Adult
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Campylobacter/isolation & purification*
;
Campylobacter Infections/microbiology
;
Campylobacter fetus/isolation & purification*
;
Colonic Neoplasms/microbiology
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Culture Media
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Human
;
Liver Cirrhosis/microbiology
;
Male
;
Middle Age
;
Septicemia/microbiology*
5.Campylobacter jejuni Bacteremia in a Liver Cirrhosis Patient and Review of Literature: A Case Study.
Jin Gu YOON ; Saem Na LEE ; Hak Jun HYUN ; Min Joo CHOI ; Ji Ho JEON ; Eunju JUNG ; Seonghui KANG ; Jeeyong KIM ; Ji Yun NOH ; Won Suk CHOI ; Joon Young SONG ; Hee Jin CHEONG ; Woo Joo KIM
Infection and Chemotherapy 2017;49(3):230-235
Campylobacter infection causes gastrointestinal symptoms such as abdominal pain or diarrhea. Occasionally, Campylobacter bacteremia affects immunocompromised patients; however, serious outcomes are known to be rare. Here, we present a case of a patient with Campylobacter bacteremia who had underlying liver cirrhosis. The patient had fever and diarrhea. These symptoms subsided after treatment with cefotaxime. Campylobacter jejuni was isolated in the blood culture after 10 days. In addition, previously reported cases of Campylobacter bacteremia in Asian countries were reviewed with respect to antimicrobial sensitivities.
Abdominal Pain
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Asian Continental Ancestry Group
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Bacteremia*
;
Campylobacter Infections
;
Campylobacter jejuni*
;
Campylobacter*
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Cefotaxime
;
Diarrhea
;
Fever
;
Humans
;
Immunocompromised Host
;
Liver Cirrhosis*
;
Liver*
6.Clinical manifestation of Campylobacter enteritis in children.
Joon Yeol BAE ; Dong Hyuk LEE ; Kyung Ok KO ; Jae Woo LIM ; Eun Jeong CHEON ; Young Hwa SONG ; Jung Min YOON
Korean Journal of Pediatrics 2018;61(3):84-89
PURPOSE: Timely antibiotic therapy in selected cases of diarrhea associated with bacterial infections can reduce the duration and severity of illness and prevent complications. The availability of a predictive index before identification of causative bacteria would aid in the choice of a therapeutic agent. METHODS: The study included patients admitted to the pediatrics unit at Konyang University Hospital for acute inflammatory diarrhea from August 1, 2015 to July 31, 2016 who underwent multiplex polymerase chain reaction testing. Of 248 patients, 83 had positive results. The clinical symptoms and blood test results were examined in 61 patients with Campylobacter spp. (25 patients), Salmonella spp. (18 patients), and Clostridium perfringens (18 patients) infections. The mean age of the 61 patients (male:femal=31:30) was 84.0±54.8 months, and the mean hospital stay was 4.6±1.7 days. RESULTS: There were no statistical differences in sex, age, clinical symptoms, or signs. Patients with Campylobacter infection were significantly older (P=0.00). C-reactive protein (CRP) levels in patients with Campylobacter infection were higher than those in the other 2 groups, at 9.6±6.1 mg/dL. The results of receiver-operating characteristic curve analysis showed that the cutoff age was ≥103.5 months (sensitivity, 72%; specificity, 86%) and the CRP cutoff level was ≥4.55 mg/dL (sensitivity, 80%; specificity, 69%). CONCLUSION: Age (≥103.5 months) and higher CRP level (≥4.55 mg/dL) were good predictors of Campylobacter enterocolitis. If neither criterion was met, Campylobacter enterocolitis was unlikely (negative predictive value 97.2%). When both criteria were met, Campylobacter enterocolitis was highly likely.
Bacteria
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Bacterial Infections
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C-Reactive Protein
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Campylobacter Infections
;
Campylobacter*
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Child*
;
Clostridium perfringens
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Diarrhea
;
Enteritis*
;
Enterocolitis
;
Hematologic Tests
;
Humans
;
Length of Stay
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Multiplex Polymerase Chain Reaction
;
Pediatrics
;
Salmonella
;
Sensitivity and Specificity
7.Emerging Infectious Disease by Industrialization and Technology.
Korean Journal of Infectious Diseases 1999;31(1):65-78
Nowadays, industrialization caused a new sort of infectious diseases which had not been noticed before. Most of them can be included into category of food-borne zoonosis, for example, Salmonella, Escherichia coli O157: H7, Campylobacter, Cyclospora cayetanensis, and new variant creutzfeldt-Jakob's disease (nvCJD). Development of diagnostic technology revealed the causative pathogen of many diseases which used to be regarded as non-infectious. The management of opportunistic infections in the increasing population of immunocompromised hosts accompanied with the progress in transplantation became a new challenge to the clinical field.
Campylobacter
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Communicable Diseases
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Communicable Diseases, Emerging*
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Cyclospora
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Escherichia coli O157
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Immunocompromised Host
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Opportunistic Infections
;
Salmonella
8.Pyogenic arthritis of the hip due to Campylobacter fetus: a case report.
Chan Dong HAN ; Jin Woo LEE ; Yunsop CHONG
Yonsei Medical Journal 1992;33(1):87-90
Septic arthritis of the hip caused by Campylobacter fetus subsp. fetusis very rare. The authoris isolated C. fetus subsp. fetus from a specimen of the left hip. The patient was a 53-year old man with a history of heavy drinking, diabetes, and chronic hepatitis, and had been suffering from avascular necrosis of both femoral heads. It was considered that the organism invaded already damaged tissue of the joint. The patient was treated with intravenous antibiotics and later received successful total hip replacement.
Arthritis, Infectious/*etiology
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*Campylobacter Infections
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Campylobacter fetus/*isolation & purification
;
Case Report
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Femur Head Necrosis/etiology
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Hip/*microbiology
;
Human
;
Male
;
Middle Age
9.Role of Cytolethal Distending Toxin in Altered Stool Form and Bowel Phenotypes in a Rat Model of Post-infectious Irritable Bowel Syndrome.
Venkata POKKUNURI ; Mark PIMENTEL ; Walter MORALES ; Sam Ryong JEE ; Joel ALPERN ; Stacy WEITSMAN ; Zachary MARSH ; Kimberly LOW ; Laura HWANG ; Reza KHOSHINI ; Gillian M BARLOW ; Hanlin WANG ; Christopher CHANG
Journal of Neurogastroenterology and Motility 2012;18(4):434-442
BACKGROUND/AIMS: Campylobacter jejuni infection is a leading cause of acute gastroenteritis, which is a trigger for post-infectious irritable bowel syndrome (PI-IBS). Cytolethal distending toxin (CDT) is expressed by enteric pathogens that cause PI-IBS. We used a rat model of PI-IBS to investigate the role of CDT in long-term altered stool form and bowel phenotypes. METHODS: Adult Sprague-Dawley rats were gavaged with wildtype C. jejuni (C+), a C. jejuni cdtB knockout (CDT-) or saline vehicle (controls). Four months after gavage, stool from 3 consecutive days was assessed for stool form and percent wet weight. Rectal tissue was analyzed for intraepithelial lymphocytes, and small intestinal tissue was stained with anti-c-kit for deep muscular plexus interstitial cells of Cajal (DMP-ICC). RESULTS: All 3 groups showed similar colonization and clearance parameters. Average 3-day stool dry weights were similar in all 3 groups, but day-to-day variability in stool form and stool dry weight were significantly different in the C+ group vs both controls (P < 0.01) and the CDT- roup (P < 0.01), but were not different in the CDT- vs controls. Similarly, rectal lymphocytes were significantly higher after C. jejuni (C+) infection vs both controls (P < 0.01) and CDT-exposed rats (P < 0.05). The counts in the latter 2 groups were not significantly different. Finally, c-kit staining revealed that DMP-ICC were reduced only in rats exposed to wildtype C. jejuni. CONCLUSIONS: In this rat model of PI-IBS, CDT appears to play a role in the development of chronic altered bowel patterns, mild chronic rectal inflammation and reduction in DMP-ICC.
Adult
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Animals
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Bacterial Toxins
;
Campylobacter Infections
;
Campylobacter jejuni
;
Colon
;
Gastroenteritis
;
Humans
;
Inflammation
;
Interstitial Cells of Cajal
;
Irritable Bowel Syndrome
;
Lymphocytes
;
Models, Animal
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Phenotype
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Rats
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Rats, Sprague-Dawley
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Weights and Measures
10.A case of chronic inflammatory demyelination polyradiculopathy related to Campylobacter jejuni infection in human and animals.
Chao LIU ; Fang-cheng CAI ; Qin LI ; Li LI ; Ping YIN
Chinese Journal of Pediatrics 2004;42(4):308-309
Animals
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Antibodies, Bacterial
;
blood
;
Campylobacter Infections
;
complications
;
microbiology
;
Campylobacter jejuni
;
isolation & purification
;
Child, Preschool
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Enzyme-Linked Immunosorbent Assay
;
Fatal Outcome
;
Humans
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Male
;
Polyradiculoneuropathy, Chronic Inflammatory Demyelinating
;
etiology
;
Swine