Campylobacter Infections ; Guillain-Barre Syndrome ; microbiology ; Humans

Campylobacter fetus subsp. intestinalis was isolated from the blood of two different patients. One patient was a 46-year-old male with liver cirrhosis and the other a 44-year-old male with co1on carcinoma. These are the second and third documented infections of this kind in Korea. Difficulties of their isolation were well illustrated. For instance, the growth was detected after a long incubation of 4 to 6 days. All of the 3 blood cultures from the carcinoma patient, but on1y 2 of 3 specimens from the other patient, yielded the organism.
Adult ; Campylobacter/isolation & purification* ; Campylobacter Infections/microbiology ; Campylobacter fetus/isolation & purification* ; Colonic Neoplasms/microbiology ; Culture Media ; Human ; Liver Cirrhosis/microbiology ; Male ; Middle Age ; Septicemia/microbiology*

Bacterial Typing Techniques ; Campylobacter Infections ; microbiology ; Campylobacter fetus ; classification ; isolation & purification ; Humans ; Multilocus Sequence Typing

OBJECTIVETo investigate the incidence of campylobacter jejuni (CJ) infection and the drug resistance of CJ in children with diarrhea in Guangzhou.

METHODSThe fecal samples of 3,351 children with diarrhea between July 2005 and June 2008 were collected for CJ culture. The species of CJ strains were identified by Lior methods. The drug susceptibility tests were performed by the Kirby-Bauer method.

RESULTSTwo hundred and sixty-seven CJ strains (8.0%) were isolated from 3,351 samples. The children at age of 1 month to 1 year were susceptible to CJ, accounting for 91.0%. A higher incidence of CJ infection (76.8%) was found in summer and autumn. The CJ strains were susceptible to imipenem, amikacin, cefoperazone/sulbactam, chloramphenicol, macrolides and lincomycins. Parts of CJ strains (20%-40%) were resistant to ampicillin, quinolones and ambramycin. All CJ strains were resistant to sulfamethoxazole/trimethoprim and cefditoren. Two hundred and one strains (75.3%) were CJ biotype I.

CONCLUSIONSCJ is an important pathogen of diarrhea in children from Guangzhou. CJ is resistant to some antibiotics used often in clinical practice, and so it is thus important to use antibiotics based on the results of drug susceptibility tests in children with CJ infection.

Campylobacter Infections ; microbiology ; Campylobacter jejuni ; classification ; drug effects ; isolation & purification ; Child, Preschool ; Diarrhea ; microbiology ; Female ; Humans ; Infant ; Male ; Microbial Sensitivity Tests

OBJECTIVETo understand the occurrence and distribution of Campylobacter jejuni in chicken in China, assess its health risk to the Chinese population, and provide recommendations for effective risk control.

METHODSData from the National Food Safety Risk Surveillance Network on Campylobacter jejuni between 2007 and 2010 and from published articles were analyzed. Eleven parameters were used based on the whole chicken preparation process and prevalence of Campylobacter jejuni for risk assessment by using the Ross-Sumner Method.

RESULTSThe detection rates of Campylobacter jejuni in raw chicken were between 0.29% and 2.28% during 2007-2010 in China (more than 20 provinces). The probability of illness caused by Campylobacter jejuni due to chicken consumption was around six out of one million consumers per day in urban areas and around one out of one million consumers per day in rural areas. Total predicted illnesses per year was about 736 000, accounting for 1.6‰ of the general population in urban areas and about 301 000, accounting for 0.37‰ of the total population in rural areas. The risk rankings of Campylobacter jejuni in chicken were 52 and 49 in urban and rural areas, respectively.

CONCLUSIONA high risk score for Campylobacter jejuni in chicken was obtained in China. This result may contribute to development of food safety management strategies. Key efforts should be made to control the risk of Campylobacter jejuni in chicken in China, especially in chick breeding and chicken preparation processes.

Animals ; Campylobacter Infections ; epidemiology ; veterinary ; Campylobacter jejuni ; Chickens ; China ; epidemiology ; Diet ; Food Handling ; Food Microbiology ; Poultry Diseases ; epidemiology ; Prevalence ; Risk Assessment ; Transportation

Septic arthritis of the hip caused by Campylobacter fetus subsp. fetusis very rare. The authoris isolated C. fetus subsp. fetus from a specimen of the left hip. The patient was a 53-year old man with a history of heavy drinking, diabetes, and chronic hepatitis, and had been suffering from avascular necrosis of both femoral heads. It was considered that the organism invaded already damaged tissue of the joint. The patient was treated with intravenous antibiotics and later received successful total hip replacement.
Arthritis, Infectious/*etiology ; *Campylobacter Infections ; Campylobacter fetus/*isolation & purification ; Case Report ; Femur Head Necrosis/etiology ; Hip/*microbiology ; Human ; Male ; Middle Age

Animals ; Antibodies, Bacterial ; blood ; Campylobacter Infections ; complications ; microbiology ; Campylobacter jejuni ; isolation & purification ; Child, Preschool ; Enzyme-Linked Immunosorbent Assay ; Fatal Outcome ; Humans ; Male ; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating ; etiology ; Swine

BACKGROUNDThere has been a marked global increase in the incidence of human Campylobacter enteritis in recent years. This study investigated the epidemiological and clinical features of Campylobacter enteritis in adult patients suffering from acute diarrhea.

METHODSThis was a retrospective review of Campylobacter enteritis in adult patients with acute diarrhea presenting at Beijing University First Hospital, Beijing, China, in the summer and autumn (April to October) of 2005 to 2009. The data collected included the species of campylobacter identified, and the age, gender, clinical manifestations and results of laboratory test on stool samples collected from the patients. Campylobacter sensitivity tests to various antimicrobial agents were conducted on 80 specimens. Chi-square tests were applied using SPSS13.0 software and a two-sided P value of < 0.05 was considered statistically significant.

RESULTSCampylobacter spp. isolated from the stool specimens of 142 patients with diarrhea represented 14.9% of all the cases examined. C. jejuni was identified in 127 patients (89.4%) and C. coli in 15 others (10.6%). The infection incidence was highest in the age range of 21 - 30 years which comprised 21.7% of the total cases examined. Most cases of diarrhea (46 patients) occurred in June. Watery diarrhea (97.2%), abdominal pain (72.5%) and fever (64.8%) were the most common manifestations of enteric campylobacteriosis. Only four patients (2.8%) had bloody diarrhea. The antimicrobial resistance rates were: cefoperazone (100%), levofloxacin (61.3%), gentamicin (12.5%), erythromycin (6.3%), and azithromycin (2.5%).

CONCLUSIONSCampylobacter was prevalent among adults with acute diarrhea from 2005 to 2009 in Beijing, China. The large number of those afflicted by the disease warrants the commission of a large multicenter study to determine the extent of enteric campylobacteriosis in this region.

Adult ; Anti-Bacterial Agents ; therapeutic use ; Campylobacter ; drug effects ; isolation & purification ; pathogenicity ; Campylobacter Infections ; drug therapy ; microbiology ; China ; Diarrhea ; drug therapy ; microbiology ; Drug Resistance, Bacterial ; Female ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Young Adult

Vibrio fetus was isolated from blood specimens of a subacute bacterial endocarditis patient. The 38 year old male patient was admitted to Severance Hospital in January 1970 for 11 days and again in July 1970 for 13 days. Subacute bacterial endocarditis was the major condtion. Aortic insufficiency and cholestatic hepatitis were the accessory diagnosis. The organism was isolated during the second admission. V. fetus human infection is known to be very rare, and the present case appears to be the first case in Korea. V. fetus grows very slowly with increased carbon dioxide tension which favours the growth. It is a slightly curved, S-shaped and spiral gram-negative organism. Many antibiotics, effective to gram negative organisms, inhibit the growth of the organism. V. fetus is an animal pathogen causing disease in ruminants. The patient enjoyed raw beef dishes. He could be infected with the organism by eating raw beef.
Adult ; Campylobacter fetus/isolation & purification ; Endocarditis, Subacute Bacterial/etiology ; Endocarditis, Subacute Bacterial/microbiology* ; Human ; Male ; Vibrio/isolation & purification* ; Vibrio Infections/microbiology*

On July 6, 2009, an outbreak of gastroenteritis occurred among middle school students in Incheon. An investigation to identify the source and describe the extent of the outbreak was conducted. A retrospective cohort study among students, teachers, and food handlers exposed to canteen food in the middle school was performed. Using self-administered questionnaires, information was collected concerning on symptoms, days that canteen food was consumed, and food items consumed. Stool samples were collected from 66 patients and 11 food handlers. The catering kitchen was inspected and food samples were taken. Of the 791 people who ate canteen food, 92 cases became ill, representing an attack rate of 11.6%. Thirty-one (40.3%) of the 77 stool specimens were positive for Campylobacter jejuni. Interviews with kitchen staff indicated the likelihood that undercooked chicken was provided. This is the first recognized major C. jejuni outbreak associated with contaminated chicken documented in Korea.
Adolescent ; Adult ; Animals ; Campylobacter Infections/*epidemiology ; *Campylobacter jejuni ; Chickens ; Cohort Studies ; *Disease Outbreaks ; Electrophoresis, Gel, Pulsed-Field ; Environmental Exposure ; Female ; Food Contamination ; Humans ; Male ; Middle Aged ; Questionnaires ; Republic of Korea ; Retrospective Studies ; Risk Factors ; Water Microbiology