A 32-year-old woman with a long-standing systemic lupus erythematosus had multiple subcutaneous nodules on her axillae, iliac crests and limbs. Three years ago, these nodules began to appear and slowly became larger. Some of them amassed to form a large, fungating, lobulated mass on her right iliac crest. Roentgenographic and histological examination showed that they were calcium deposits. She was initially treated with aluminum hydroxide administration for nine months, which resulted in moderate decrease in size and softening in consistency, but not complete resolution. Then, the mass on the right iliac crest was excised, with an excellent early result.
Administration, Oral ; Adult ; Aluminum Hydroxide/therapeutic use* ; Biopsy ; Calcinosis/therapy* ; Calcinosis/etiology ; Calcinosis/diagnosis ; Case Report ; Female ; Human ; Lupus Erythematosus, Systemic/complications* ; Skin Diseases/therapy* ; Skin Diseases/etiology ; Skin Diseases/diagnosis

A 32-year-old woman with a long-standing systemic lupus erythematosus had multiple subcutaneous nodules on her axillae, iliac crests and limbs. Three years ago, these nodules began to appear and slowly became larger. Some of them amassed to form a large, fungating, lobulated mass on her right iliac crest. Roentgenographic and histological examination showed that they were calcium deposits. She was initially treated with aluminum hydroxide administration for nine months, which resulted in moderate decrease in size and softening in consistency, but not complete resolution. Then, the mass on the right iliac crest was excised, with an excellent early result.
Administration, Oral ; Adult ; Aluminum Hydroxide/therapeutic use* ; Biopsy ; Calcinosis/therapy* ; Calcinosis/etiology ; Calcinosis/diagnosis ; Case Report ; Female ; Human ; Lupus Erythematosus, Systemic/complications* ; Skin Diseases/therapy* ; Skin Diseases/etiology ; Skin Diseases/diagnosis

Calcinosis ; Cardiomyopathies ; complications ; pathology ; Heart Ventricles ; Humans ; Male ; Middle Aged ; Tachycardia, Ventricular ; etiology

A 16-year-old female patient with systemic lupus erythematosus (SLE) presented with abdominal pain and oliguria, after one month of hospital treatment with methylprednisolone and cyclophosphamide. Computed tomography of the abdomen revealed the calcification of bilateral superior segmental ureteral wall. Computed tomography urography revealed stenosis of bilateral ureters. This calcification may be associated with lupus-induced inflammatory reaction of ureteral endomembrane. By receiving the ureteral catheters, her abdominal pain and oliguria had been completely resolved. After discharge, she underwent the surgery of cutaneous ureterostomy in the local hospital. During two years follow-up, her condition is stable without any symptom of the urinary system.
Adolescent ; Calcinosis ; diagnosis ; etiology ; Female ; Humans ; Lupus Erythematosus, Systemic ; complications ; Ureter ; pathology

The authors investigated the relationship between anger and the calcification of the coronary artery in individuals with and without risk factors for coronary artery disease in Korea. Sixty-one subjects with risk factors of coronary artery disease and 31 subjects without risk factors were enrolled in this study. Electron Beam Computed Tomography was used to measure the calcium level of coronary artery. The anger expression scale was used to measure the anger levels. The anxiety, depression, hostility, and somatization subscales of the symptom checklist-90-revised (SCL-90-R) and the global assessment of recent stress (GARS) scale were used to assess the psychopathology and perceived stress. The logistic regression analysis results showed that only the anger-total score was significantly associated with the coronary calcification regardless of the risk factors. These results suggest that anger plays an important role in the calcification of the coronary artery.
Adult ; Aged ; *Anger ; Calcinosis/*etiology ; Coronary Arteriosclerosis/*etiology ; Female ; Human ; Lipids/blood ; Male ; Middle Aged ; Risk Factors

Calcinosis ; etiology ; Cardiomyopathies ; etiology ; Heart Septum ; pathology ; Heart Valve Prosthesis ; adverse effects ; Humans ; Male ; Middle Aged ; Mitral Valve ; surgery

Tympanosclerosis is the middle ear tissue hyalinization and calcification caused by chronic middle ear inflammation, which mainly results in conductive deafness with unobvious clinical symptom. Etiology is unclear. The treatment is given priority to surgical treatment at present, while long-term effect reported mostly poor. This article analyzed etiology and treatment of the tympanic cavity sclerosis.
Calcinosis ; Chronic Disease ; Ear, Middle ; Hearing Loss, Conductive ; etiology ; Humans ; Myringosclerosis ; complications ; etiology ; therapy ; Otitis Media ; Sclerosis

Hypercalcemia in accelerated phase of chronic myelogenous leukemia (CML) is very rare. Its pathogenesis is considered humoral hypercalcemia of malignancies mediated by parathyroid hormone-related protein (PTHrP). In severe hypercalcemia, calcifications in kidneys, skin, vessels, heart, and stomach may occur. Our two cases were admitted because of severe hypercalcemia in accelerated phase of CML. On Tc-99m methylene diphosphonate (MDP) bone scintigraphies, a marked tracer accumulation was seen in the lung, heart, stomach and kidney. We report increased tracer accumulation of multiple organs on Tc-99m MDP bone scintigraphy in two rare hypercalcemic patients with CML.
Adult ; Bone Diseases/radionuclide imaging* ; Bone Diseases/etiology* ; Calcinosis/radionuclide imaging ; Calcinosis/etiology ; Case Report ; Human ; Hypercalcemia/radionuclide imaging* ; Hypercalcemia/etiology* ; Leukemia, Myeloid, Chronic/metabolism ; Leukemia, Myeloid, Chronic/complications* ; Male ; Middle Age ; Proteins/metabolism ; Technetium/diagnostic use

Fresh dental calculus were scratched and rinsed with distilled water, and then dissolved by HNO3. Simulated body fluid was used as control. Aqueous ammonia was added to step up the pH. FSEM and FI-IR were used to analyze the crystal character of deposition. Turbid occurred when pH = 5.4 and deposition occurred when pH = 5.6. Ribbon-like crystal, which was the same as the crystal in natural dental calculus was observed in experimental group and was evidenced to be hydroxyapatite (HAP) by FT-IR. HAP formation through homogeneous phase redeposition of dissolved dental subgingival calculus may be related with the existing template molecules in dental subgingival calculus resolution, which induce the biomineralization of HAP formation.
Calcinosis ; pathology ; Calcium Phosphates ; chemistry ; Crystallography ; Dental Calculus ; chemistry ; Dental Plaque ; chemistry ; Gingival Diseases ; etiology ; Humans ; Hydroxyapatites ; chemistry

Adolescent ; Basal Ganglia ; pathology ; Calcinosis ; Child ; Child, Preschool ; Female ; Humans ; Infant ; Male ; Risk Factors ; Stroke ; etiology ; Wounds and Injuries