Objective To investigate the angioarchitecture and the efficacy of endovascular embolization of uterine fibroids. Methods Bilateral internal iliac and uterine arteriography were performed to domonstrate the angioarchitecture in uterine fibroids with Seldinger technique. The feeding arteries of uterine fibroids were super-selectively embolized. Results The uterine arteries of 30 patients all originated from the iliac arteries of the ipsilateral side. The feeding arteries of uterine fibroids showed bilateral dominance in 16 cases (53%), unilateral dominance in 11 (37%) and unilateral feeding in only 3(10%). All symptoms disappeared after embolization. The fibroids masses decreased averagely by 40% in size at 3-month with ultrasound follow-up, by 55% at 6 months and by 60% at 12 months with a total clinical efficacy of 100%. Conclusions The key to efficacy and prevention of relapse is to understand the angioarchitecture in order to occlude all the pathological vessels in uterine fibroids.

Objective To explore the clinical significance of plasma fibrinogen(FIB)and plasma D-dimer (D-D)changes involved in lung cancer patients before and after interventional therapy.Methods 23 patients with lung cancer,27 cases of normal control group collected at the same time,to compared the difference of plasma FIB between patients with lung cancer and the normal control group.All enrolled patients were treated with bronchial artery infusion chemotherapy.Plasma FIB and D-D of all patients were meas-ured before the first and the third interventional therapy.Results Plasma FIB value of patients before interventional therapy was sig-nificantly higher than that of the normal control group and the group after interventional therapy.The difference between the group after interventional therapy and the normal control group was no significant;Plasma D-D value of patients before and after interven-tional therapy was significant.Conclusion Changes of plasma FIB and D-D before and after interventional therapy in patients with lung cancer are significantly correlated with the severity of the disease and interventional therapy efficacy,which can be used as a ver-y meaningful indicator of interventional therapy.

Ethylene vinyl alchohol copolymer can be developed into new kinds of liquid embolization material possessing a great number of advantages in comparison with the current embolization substarces. The authors reviewed the advancement of ethylene vinyl alchohol copolymer in the treatment of cerebral arteriovenous malformation in recent years.

Objective To explore the correlation between the change of CT value of osteolytic bone metastasis after the treatment of zoledronic acid and bone metabolism before treatment in breast cancer patients.Methods Twenty breast cancer patients with osteolytic bone metastases were diagnosed by 99m Tc-MDP bone scintigraphy and 99m Tc-MDP SPECT/CT ( contain 16-slice spiral CT) for the first time entered this study.After treatment of zoledronic acid for 3-12 months with the same method, 99m Tc-MDP bone scintigraphy and 99mTc-MDP SPECT/CT were peformed in the 20 breast cancer patients again with the same CT scan parameters(voltages:120kV, tube currents:80mA, pitches:3.75mm).With using regions of interesting (ROI)technique, the T/NT value of osteolytic bone metastases in the first 99m Tc-MDP bone scintigraphy were measured.The CT value of same ROI before and after zoledronic acid therapy were measured (CT1 and CT2), and the change of CT value (△CT,△CT=CT2-CT1) were calculated.The correlation between them were analyzed. SPSS 16.0 was applied for variance and linear correlation analyses.Results (1)A total of 30 lesions of osteolytic bone metastases were detected in the 20 breast cancer patients by the first 99m Tc-MDP bone scintigraphy and 99m Tc-MDP SPECT/CT.The CT value before therapy was significantly higher than that after therapy(425 ±152HU vs 120 ±73HU, t=9.95, P<0.01).(2)The change of CT value after therapy was positively correlated with and the T/NT value of osteolytic bone metastasis(r=0.907, P<0.01).(3)The change of CT value of positive lesions after therapy was significantly higher than that of negative lesions by 99mTc-MDP bone scan(W=15,P=0.001). Conclusion 99m Tc-MDP bone scintigraphy provides an effective method to predict the efficacy of zoledronic acid for breast cancer pa-tients with osteolytic bone metastases.The breast cancer patients with high bone metabolism should be recommended zoledronic acid thera-py, conversely should not be recommended.

Objective To study the efficiency of inhaling nitrogen monoxide in labor on pain relief and its effect on mother and fetus. Methods Two hundred term primiparas were randomly divided into the observational and control group.The control group was given the same treatments as that in the observational group except for inhaling of nitrogen monoxide. The degree of labor pains, duration of labor, mode of delivery, Apgar scores, the volume of intrapartum bleeding, the rate of postpartum hemorrhage and other outcomes were compared between the two groups. Results The scores of labor pains in the observational group was significantly lower(P

The root canals of 95 maxillary second primary molars were explored by 10#file combined with 17%EDTA.The canal orifice was observed and orientated by endoscope.Hand instruments were used for root canal preparation and screw conveyor was used to fill the ca-nal with Vitapex paste.MB2 was found in 14 of the 95 molars(14.7%).MB2 orifice was usually located mesially along MB-P.

Objective To investigate the kinetics of PML-RARα fusion gene in acute promyelocytic leukemia(APL)to monitor minimal residual disease(MRD). Methods In induction therapy,consolidation and maintenance therapy courses, PML-RARα fusion gene was performed by RT-PCR. Results The long-term follow-up of 18 cases achieved complete remission (CR),two cases experienced molecular relapse. One case relapsed at 4 months after CR1 and achieved CR2 after induction therapy. However, molecular and hematology relapsed again at 2 months after CR2 and re-achieved CR3. The other case relapsed at 74 months after CR1 and achieved CR2 after induction treatment, who had survived for 106 months until the end of follow-up. Conclusion RT-PCR assay for detection of PML-RARα should be performed regularly during CR period so as to find molecular relapse eady. Hematological relapse could potentially be averted through treatment modification according to molecular monitoring results of PML-RARα.

Objective To evaluate CRP,peripheral WBC and neutrophil for the risk of coronary heart disease.Methods Plasma CRP levels,peripheral WBC and neutrophil count of 68 acute coronary syndrome(ACS)patients,28 stable angina(SA)patients and 33 controls were measured.Results There were significant differences of CRP levels,peripheral WBC and neutrophil count between the ACS group and the SA group or control group;CRP levels,peripheral WBC and neutrophil count in acute myocardial infarction(AMI)patients were much higher than those in unstable angina(UA)patients,SA patients and controls(P

OBJECTIVE To inquire into the risk factors of uremia patients with fungus infection and search for the effective methods to prevent and control it.METHODS All the cases of the 82 uremia patients with fungus infection in the clinic of our hospital were analyzed.RESULTS The sites of the fungus infection were intestines and stomach,blood vessel,respiratory tract,oral cavity,reproductive tract,skin soft tissue and urinary tract.The common fungus infection was Candida albicans,about 60.61 per cent.The risk factors of uremia patients with fungus infection were the old age,several underlying diseases,hypoimmunity,not using medicine properly during the treatment and invasive operation.CONCLUSIONS The effective methods to prevent and control fungus infection are as the follows: to improve the staff′s awareness of the danger of fungus infection,be strict to the rules of hospital isolation and sterilization,and be try to reduce invasive operation.We should strengthen the cleaning of the wards and the crew's hands,strengthen the monitoring of quality and pay more attention to the primary treatment.We should use the medicine properly,especially the use of antibiotics,immune suppressants and hormones,and pay attention to result of culture from the microbiological laboratory.We should cure the underlying diseases actively and improve the suffers′ immunity function.

Objective To establish a test method for determining the vitamin B4 tablets dissolution.Methods Paddle method was used to 900 mL pH6.8 phosphate buffer solution as the dissolution medium, the temperature of 37℃, the speed of 50 r/min, take time for 45 min.Taking the filtrate through the 0.45μm microporous membrane filtration, vitamin B4 tablets dissolution quantity determined by ultraviolet spectrophotometry, determined the wavelength of 262 nm, dissolution limit for 80% of the labeled amount.Results Vitamin B4 concentration had a good linear relationship with the absorbance in 4~16μg/mL, r=0.9999 (n =5), the average recovery was 100.1%, RSD =1.0% (n=9).Conclusion The method is simple, sensitive and accurate, has certain effect on prescription and study of the process of different production enterprises, can be used for the dissolution determination of vitamin B4 tablets.