1.Effective analysis on the treatment of severe acute pancreatitis withXueBiJing injection and conventional therapy of western medicine
International Journal of Traditional Chinese Medicine 2015;(5):405-408
Objective To evaluate the effects of treating severe acute pancreatitis (SAP) with XueBiJing injection and conventional therapy of western medicine.Methods This study was a randomized controlled study. 104 patients meet the inclusion criteria of SAP were randomly divided into a routine treatment group (52 cases) and aXuebijing treatment group (52 cases). Patients of both groups received immediate rescue together with performing ECG monitoring, fasting food, inhaling oxygen. On such basis, the conventional treatment group was treated with inhibiting enzyme activity and resisting infection; WhileXuebijing treatment group was treated withXuebijing injection on the basis of the conventional treatment group. After 7 days treatment, the therapeutic effect, WBC, CRP, blood and urinary amylase, TNF-α, LPS, and IL-6 were observed in both groups.Results The total effective rates in the treatment group and the control group were 92.31%(48/52)and 73.08%(38/52), respectively, with statistical difference(χ2=5.442,P=0.020). After the treatment, WBC (9.2 ×109/L ± 2.1 ×109/Lvs.12.2 ×109/L ± 3.1 ×109/L;t=5.778,P=0.000), amylase blood serum (305.4 ± 100.9 U/Lvs. 403.5 ± 197.8 U/L;t=3.186,P=0.002) and urine (702.3 ± 98.5 U/Lvs.1 102.4 ± 202.6 U/L;t=12.807,P=0.000), TNF-α (21.2 ± 9.1 ng/mlvs.27.5 ± 13.4 ng/ml;t=2.805,P=0.006), CPR (7.6 ±3.8 mg/Lvs.15.2 ± 9.8 mg/L;t=5.214,P=0.000), LPS (146.3 ± 52.1 EU/Lvs.281.2 ± 91.7 EU/L;t=9.224, P=0.000), and IL-6 (143.4 ± 52.4 ng/mlvs. 203.7 ± 79.8 ng/ml;t=4.555,P=0.000) in the treatment group were significantly reduced than those in the control group. The times to remission of abdominal distension (5.3 ± 1.3 d vs.6.1 ± 2.5 d;t=2.047,P=0.043) and abdominal paln (4.9 ± 2.3 dvs.6.0 ± 3.1 d;t=2.055,P=0.042), return to normal body temperature (4.3 ± 1.8 dvs.5.5 ± 2.1 d;t=3.129,P=0.002) in the treatment group were all significantly decreased than those in the control group.ConclusionXueBiJinginjection adjuvant to conventional therapy can effectively improve reduction of amylase in blood serum and urine, and symptoms remission,and also shorten treatment time in patients with SAP.
2.Sunsimiao's Medical Morality and Chinese Humane Spirit
Chinese Medical Ethics 1995;0(04):-
Sumsimiao's medical morality thoughts attach great importance to the internal life and its quality.It is what the essence of medical humane spirit is,and also what people of the age need.In spite of technology developing in a fantastic speed,modern medicine tends to shrink in humane spirit.Whereupon,it's the medical personnel and whole society's duty to advocate Sumsimiao's thoughts,ponder the function and quality of medicine,and restore the medical humane spirit.
3.Influence of maternal H1N1 influenza on perinatal outcomes
Chinese Journal of Perinatal Medicine 2010;13(5):371-374
Objective To discuss the influence of H1N1 influenza on maternal and fetal outcomes and obstetric management. Methods Totally, data were collected on 19 women, affected by H1N1 influenza and admitted to Shengjing Hospital of China Medical University from November 7, 2009 to December 15,2009, and retrospective analysis was performed on the maternal and fetal outcomes. Results Among the 19 cases, three were( 15. 8%, 3/19) in puerperium, who were all mild cases and recovered. Sixteen (84.2%, 16/19)women were diagnosed as H1N1 influenza during pregnancy, among which two in early pregnancy (12. 5%), seven (43. 8%) in mid-term pregnancy and seven (43. 8%) in late pregnancy. According to the severity of H1N1 influenza, six were mild cases (37. 5% ,6/16), two (12. 5% ,2/16)were severe cases and eight (50. 0% ,8/16)were critical. For these 16 pregnant women, thc two cases in early pregnancy (mild cases) were terminated after recovery from H1N1 influenza. Among the seven mid-term cases, four mild and one of the three severe and critical cases delivered till term, and two of the three severe and critical cases were delivered abdominally because of fetal death intrauterine or maternal severe complications at 27 or 23 weeks of gestation. All of the seven late pregnant cases underwent emergent cesarean section due to maternal or fetal reasons, and two fetuses died in the uterus at late pregnancy and five survived including four preterm babies and one full term baby. Altogether, nine cases (56. 3%, 9/16)underwent emergent cesarean section, and six babies born alive and five survived without any symptom of influenza, two women died (10. 5%,2/19) after the operation. Conclusions Pregnant women during late pregnancy infected by H1N1 influenza are susceptible to develop into severe and critical conditions. Termination of the pregnancy in time is effective in both life-saving of the mothers and babies and prevent neonatal infection against H1N1.
4.ANALYSIS AND EVALUATION OF THE NUTRITIONAL COMPONENTS OF SALICORNIA BIGELOVII TORR.
Meizhen CHEN ; Weizhou CHEN ; Caixia SONG
Acta Nutrimenta Sinica 1956;0(03):-
464 g/kg.Conclusion The nutrients of Salicornia bigelovii Torr.are rich,safe to eat,and worth to develop and utilize.
5.A Study of Semantic Memory in Early Alzheimer's Disease
Wenwei XU ; Caixia CHEN ; Zaohuo CHENG
Chinese Journal of Clinical Psychology 2006;0(05):-
Objective: To evaluate the impairment of semantic memory in Alzheimer's disease.Methods: 22 Alzheimer's disease patients were examined by means of a longitudinal study and compared with 22 normal elders.Two semantic tasks,lexical decision task and semantic knowledge task were used,to evaluate the integrity of the same concepts.Results: In each session,the MMSE scores of the Alzheimer's disease group were significantly worse(P
6.Effect of compound-fluoride preparation (Co-F) on synthetic hydroxyapatite
Jixu HOU ; Caixia ZHANG ; Demin CHEN
Journal of Practical Stomatology 2001;0(01):-
砄bjective: To compare the effects of compound fluoride preparation(Co F) on the inorganic phases of the teeth with those of ZnF 2 .Methods: Synthetic hydroxyapatite(HA) was immersed into Co F containing ZnF 2, SrF 2. LiF and CaF 2, and with F - concentration of 3 500 mg/L, or into saturated ZnF 2 solution with F - concentration of 3 200 mg/L or into NaF solution with F - concentration of 3 500 mg/L for 1 and 10 days respectively. Fluoride absorption into HA was measured by X ray diffraction analysis. Results: F - absorption (?g/g) of HA in NaF solution for 1 day and 10 days were 781.81?94.38 and 805.25?87.11; that in ZnF 2 5 764.93?726.58 and 7 177.33?1 498.37, in Co F 4 901.68?680.02 and 7 136.19?461.56, respectively. KOH F(?g/g) of HA in NaF solution for 1 and 10 days were 94.96?8.28 and 151.10?19.79, that in ZnF 2 230.8?25.08 and 6 576.89?1 440.17, in Co F 1 168.18?69.42 and 4 336.72?363.16, respectively. Conclusion: ZnF 2 contained in the Co F is very important in respect of the increase of fluoride absorption.
7.Effect of Gongxuening capsule on inflammation and bleeding of instant placement IUD in cesarean section
Caixia WANG ; Ningshuang JI ; Tingting CHEN
Chinese Journal of Biochemical Pharmaceutics 2016;36(8):85-87
Objective To explore the effect of Gongxuening capsule on inflammation,postpartum hemorrhage and the amount of lochia duration of instant placement intrauterine device(IUD)in patients with cesarean section.Methods 210 cases of cesarean section immediately placed IUD patients as the research object,were divided into the observation group and the control group by simple random number table method,control group of 105 patients with cesarean section immediate postplacental IUD, observation group were given Gongxuening gapsule on the basis of the patients in the control group.The inflammatory cytokines(IL-6,IL-8,IL-10,TNF-α)levels,the amount of postpartum hemorrhage,puerperal pathology and duration of lochia related indicators were compared between two groups of patients.Results After treatment,the IL-6,IL-8,IL-10,TNF-αlevels in observation group were significantly lower than that of control group(P<0.05),postpartum hemorrhage 24h were significantly less than the control group(P<0.05).There was no significant difference in average body temperature,white blood cell count,neutrophil ratio and puerperal disease rate between observation group and control group.The maternal postpartum <28 days wa 33 cases,which was higher than 26 cases in control were,the difference was statistically significant (P<0.05).There was no significant difference in maternal postpartum from 28 d to 42 d,or >42 d between two groups.Conclusion Gongxuening capsule helps reduce postpartum hemorrhage,the degree of inhibition of inflammatory reaction in patients of cesarean section immediately placed IUD.
8.Effects of Total Saponins of Panax Ginseng Combined with Icariin on Learning, Memory and Apoptosis of Hippocampal Neural Cells in Vascular Dementia Rats
Caixia ZHENG ; Xiping LI ; Liping CHEN
China Pharmacist 2014;(9):1444-1446,1447
Objective:To explore the effects of total saponins of panax ginseng ( TSPG) combined with icariin ( ICA) on learning and memory capability, oxygen free radical and apoptosis of hippocampal CA1 pyramidal cells in vascular dementia ( VD) rats. Meth-ods:The VD rats were obtained by occlusion of bilateral common carotid artery and reperfusion repeatedly combined with intraperitoneal injection of sodium nitroprusside. Spacial learning and memory ability was evaluated by 8-arm radial electric maze test on the 21st day af-ter the drug treatment, the activity of SOD and the level of MDA in the brain were determined, and the adjacent sections were used to de-tect fragmented DNA in apoptotic cells( TUNEL) . Results:The learning and memory ability of the model rats judged by the 8-arm radial electric maze test was significantly decreased compared with that in the sham-operated group (P <0.05). The combination treatment could significantly protect and improve all the evaluated indices of the model rats after the 3-week treatment (P<0. 05) with increased SOD (P<0. 05), and decreased MDA (P<0. 01) and TUNEL positive cells (P<0. 05). Conclusion:The combination drug treatment can significantly protect and improve the spacial learning and memory ability of VD rats, which is related with such effects as improving oxygen free radical metabolism and nerve cell injure in hippocampal CA1 region.
9.Clinical observation of curative effect of manual milk on acute mastitis caused by the milk siltation
Junlan WU ; Miaofen TANG ; Caixia CHEN
Chinese Journal of Primary Medicine and Pharmacy 2017;24(13):1988-1991
Objective To explore the clinical effect of manual milk on acute mastitis caused by the milk siltation.Methods 118 patients with galactostasis induced acute mastitis were selected as the research subjects.They were divided into two groups according to the treatment sequence number and the single number,59 cases in each group.The control group was treated with routine drug therapy,the observation group was treated with manual drainage.The clinical therapeutic effect was analyzed.Results The effective rate of observation group was 96.61%,which was significantly higher than 81.36% in the control group,the difference was statistically significant (χ2=6.83,P<0.05).The scores of symptom and sign in the control group and observation group were (14.22±1.45)points and (4.02±0.44)points,which were significantly reduced than before treatment (t=6.63,9.52,all P<0.05),and the difference between the two groups was statistically significant (t=8.68,P<0.05).The tumor dissipation time[(1.89±0.23)d],milk patency time[(3.29±0.38)d],local pain relief time[(2.18±0.54)d]and body temperature return to normal time[(3.55±0.43)d]in the observation group were significantly shorter than those in the control group,the differences were statistically significant (t=7.30,6.88,7.81,6.57,all P<0.05).Conclusion The effect is superior to conventional drugs in the treatment of acute mastitis caused by the milk siltation,it can rapidly improve clinical symptoms,shorten the treatment time,and can be used as the first choice for clinical treatment.
10.A study on Genetic Polymorphism of GPT loci by FLDAS-PCR and PCR-RFLP
Caixia ZHAO ; Hui CHEN ; Haiyan SONG
Chinese Journal of Forensic Medicine 1986;0(02):-
Objective To establish a new allele specific PCR method for GPT typing: and study GPT polymorphism by FLDAS-PCR and PCR-RFLP. Method 248 unrelated individuals of Han were genotyped using FLDAS-PCR and PCR-RFLP. Results Three genotypes were identified with DP of 0.631 in Han population. Typing results by FLDAS-PCR were completely consistent with those by PCR-RFLP. The allele frequencies were GPT * 1 = 0.5423 and GPT * 2 = 0.4577. The population data fitted the Hardy-Weinberg law. Conclusion GPT-FLDAS-PCR and GPT-RFLP method is useful for forensic identification.