1.Application of empowerment theory in health education for patients with coronary heart disease after percutaneous coronary intervention in community
Chinese Journal of Practical Nursing 2012;28(31):45-47
Objective To explore the application of empowerment theory in health education for patients with coronary heart disease after percutaneous coronary intervention(PCI).Methods 68 patients were allocated into the intervention group and the control group with 34 patients in each group.The intervention group received health education guided by empowerment theory and the control group received only traditional health education.Coronary heart disease empowerment scale was recorded before and after intervention for both groups.Clinical symptoms and coronary angiography were observed 6 months after PCI for both groups.Results The total coronary heart disease empowerment scale score and all subscales of the intervention group were improved after intervention,as well as the control group.After 6 months,rate of angina pectoris and the rate of restenosis examined by coronary angiography were lower than those of the control group.Conclusions The health education guided by empowerment theory can effectively improve the psychosocial status as well as the long-term effect of PCI.
2.Simultaneous improvement to solubility and bioavailability of active natural compound isosteviol using cyclodextrin metal-organic frameworks.
Xiaojin CHEN ; Tao GUO ; Kaikai ZHANG ; Jiacai CHEN ; Caifen WANG ; Xiaohong REN ; Qin WANG ; Yingchao YANG ; Chongjing LIU ; Wen TAN ; Shuangying GUI ; Li WU ; Jiwen ZHANG
Acta Pharmaceutica Sinica B 2021;11(9):2914-2923
Cyclodextrin metal-organic framework (CD-MOF) as a highly porous supramolecular carrier could be one of the solutions to the insolubility of isosteviol (STV). The solubility of STV was lower than 20.00 ng/mL at pH 1.0 and pH 4.5, whilst its solubility increased to 20,074.30 ng/mL at pH 6.8 and 129.58 ng/mL in water with a significant pH-dependence. The