1.Changes of the T peak-T end interval, the heart function and left ventricular remodeling after partial revascularization in the elderly patients with multivessel coronary artery disease
Xiangru LIU ; Chunshi TANG ; Caian WANG ; Shihuang LI ; Ying CHEN ; Lu PENG ; Kan XIAO
Clinical Medicine of China 2013;(1):24-26
Objective To evaluate the outcome of incomplete revasculariszation by percutaneous coronary intervention (PCI) in elderly patients with coronary artery disease.Methods Data of 48 patients (age≥75 years old) underwent incomplete coronary revascularization during the period from 2008 to 2011 were collected.Their data before PCI and the 6 months follow-up results were comparatively analyzed.Results Six months after incomplete coronary revascularization,the LVEF was higher than that before revascularization ((48.10 ± 7.19)% vs (39.82 ± 8.23)%) and BNP declined significantly ((575.17 ± 67.27) ng/L vs (793.57 ± 87.53)ng/L).T peak-T end (Tp-Te) √RR and Tp-Te/QT also declined significantly (Tp-Te √RR:(96.38 ± 10.79)ms vs (147.81 ± 17.32)ms;Tp-Te/QT:(0.25 ±0.05) vs (0.30 ±0.07)) (P <0.05).Six months after PCI,LVEDV and LVESV were higher than those before surgery,but there was no significant difference(P > 0.05).Conclusion Incomplete coronary revascularization can improve heart function and stability of cardiac electrophysiology in elderly patients with coronary artery disease,but it can not prevent the development of left ventricular remodeling.
2.Influence of nifedipine controlled release tablets combined with indapamide on renal function of elderly patients with refractory isolated systolic hypertension
Xiangru LIU ; Caian WANG ; Chunshi TANG ; Shihuang LI ; Kan XIAO ; Lu PENG ; Chaoxiong CHEN
Journal of Clinical Medicine in Practice 2014;(7):79-80,93
Objective To explore the influence of nifedipine controlled release tablets com-bined with indapamide on renal function of elderly patients with refractory isolated systolic hyper-tension.Methods 96 elderly patients with isolated systolic hypertension were randomly divided in-to two groups according to the admission odd and even day,48 cases in each group.Control group was treated with nifedipine controlled release tablets,while the observation group was treated with nifedipine controlled release tablets combined with indapamide on the basis of control group.Result After treatment,blood pressure in both groups decreased,and decreasing range of blood pressure in observation group was significantly greater than the control group(P <0.05).There were signif-icant differences of serum creatinine,creatinine clearance rate and microalbuminuria detection result before and after treatment in observation group (P <0.05).Conclusion Nifedipine controlled re-lease tablets combined with indapamide can effectively reduce blood pressure and promote renal func-tion in elderly patients with refractory isolated systolic hypertension,so it is worthy of clinical popu-larization.
3.Influence of nifedipine controlled release tablets combined with indapamide on renal function of elderly patients with refractory isolated systolic hypertension
Xiangru LIU ; Caian WANG ; Chunshi TANG ; Shihuang LI ; Kan XIAO ; Lu PENG ; Chaoxiong CHEN
Journal of Clinical Medicine in Practice 2014;(7):79-80,93
Objective To explore the influence of nifedipine controlled release tablets com-bined with indapamide on renal function of elderly patients with refractory isolated systolic hyper-tension.Methods 96 elderly patients with isolated systolic hypertension were randomly divided in-to two groups according to the admission odd and even day,48 cases in each group.Control group was treated with nifedipine controlled release tablets,while the observation group was treated with nifedipine controlled release tablets combined with indapamide on the basis of control group.Result After treatment,blood pressure in both groups decreased,and decreasing range of blood pressure in observation group was significantly greater than the control group(P <0.05).There were signif-icant differences of serum creatinine,creatinine clearance rate and microalbuminuria detection result before and after treatment in observation group (P <0.05).Conclusion Nifedipine controlled re-lease tablets combined with indapamide can effectively reduce blood pressure and promote renal func-tion in elderly patients with refractory isolated systolic hypertension,so it is worthy of clinical popu-larization.