1.Congenital Café-au-Lait Spot and Sequentially Occurred Nevus Spilus.
Annals of Dermatology 2004;16(4):191-193
No abstract available.
Cafe-au-Lait Spots
;
Nevus*
2.Isodicentric Chromosome 15 Syndrome in a Korean Patient With Cafe-au-lait Spots.
John Hoon RIM ; Hee Jung CHUNG ; Saeam SHIN ; Seo Jin PARK ; Jong Rak CHOI
Annals of Laboratory Medicine 2015;35(4):474-476
No abstract available.
Cafe-au-Lait Spots*
;
Chromosomes, Human, Pair 15*
;
Humans
3.Treatment of Hyperpigmented Disease with 4-Isopropylcatechol.
Dong Gil BYUN ; Joung Hoe KIM ; Yang Ja PARK ; Soon Bok LEE
Korean Journal of Dermatology 1975;13(1):5-7
Disfiguring hyperpigmentation of the exposed areas may have impartant and lasting effects on the emotional well-being of the patient. And many attempts to treat areas of hyperpigmentation have been earried out, but all of them are not very successful. Recently 4-isopropylcatechol has been known to inhibit melanin pigmentation with a selective action on melanocytes either destroying or inactivating the melanocytes experimentally. There is no report on its clinical trial till now. In this study, 1% 4-isopropylcatechol cream was topieally applied to the hyperpigmented lesions of 29 patieots of melasma, freckle, and cafe-au-lait spot. The bleaching effect on meiasmas was very satisfactory in all patients but coantact dermatltis in 3 patients and reticular hyperpigmentation with areas of depigmented spots in one patient were developed as the side effects of the drug. Freckle and cafe-au-Iait spots were not bleached.
Cafe-au-Lait Spots
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Humans
;
Hyperpigmentation
;
Melanins
;
Melanocytes
;
Melanosis
;
Pigmentation
4.Histopathological Observation of Cafe au Lait Spots.
Sung Jun CHOI ; Hee Joon YU ; Sook Ja SOHN
Korean Journal of Dermatology 1986;24(4):506-509
We observed 17 cases of cafe au lait spots histopathplogi ally. Out of 17 cases, 9 cases were neurofibromatosis with neurofibromas, 6 cases were neurofibromatosis without neurofibroma, and 2 cases were normal healthy persons. The results were as follows. l. In all 17 cases, melanin pigment was increased in melanocytes and keratinocytes. 2. Griant pigment granules were identified only in 3 cases of neurofibromatosis with neurofibromas.
Cafe-au-Lait Spots*
;
Humans
;
Keratinocytes
;
Melanins
;
Melanocytes
;
Neurofibroma
;
Neurofibromatoses
5.A Case Congenital Pseudarthrosis of Tibia
Te Hyun YOON ; Young Hwan SHIN ; Ok Suck KIM
The Journal of the Korean Orthopaedic Association 1979;14(4):648-652
Congenital pseudarthrosis of the tibia is a condition most often combined with cafe-au-lait spots and neurofibromatosis. It is notoriously difficult to attain a sound bony union. Compression plating and screw fixation with massive bone graft resulted in successful union in our case.
Cafe-au-Lait Spots
;
Neurofibromatoses
;
Pseudarthrosis
;
Tibia
;
Transplants
6.A Case of Eyelid Neurofibroma in yon Recklinghausen's Disease.
Moon Cheon HAH ; Yeong Ja HAN ; Seung Ho HONG
Journal of the Korean Ophthalmological Society 1974;15(4):361-363
We experienced a case of eyelid neurofibroma in von Recklinghausen's disease, which had a typical sign, cafe-au-lait spots on generalized skin. The patient was a five year old girl who had no family history, and whose mentality was subnormal. The right eyelid, in which the neurofibroma involved, was thickened, and was ptotic. The surgical correction of the right eyelid ptosis was not satisfied.
Blepharoptosis
;
Cafe-au-Lait Spots
;
Eyelids*
;
Female
;
Humans
;
Neurofibroma*
;
Neurofibromatosis 1
;
Skin
7.Retroperitoneal Malignant Peripheral Nerve Sheath Tumors Complicated with Type I Neurofibromatosis.
Bonuk GU ; Jin Woo PARK ; Lee Chan JANG ; Seok Hyung KIM ; Il Hun BAE ; Woo Yoon PARK ; Seung Tak KIM
Journal of the Korean Surgical Society 2006;71(5):365-370
Neurofibromatosis is an infrequent genetic disorder that was first clinically described by von Recklinghausen and it was classified into 7 types by Riccardi. Type I neurofibromatosis is the most common type, and it is characterized by neurofibromas of variable size and multiple cafe-au-lait spots with minimal CNS lesion, if any. Malignant tumors develop in 2 to 13% of patients with type I neurofibromatosis, but they are rarely found in the retroperitoneum. We surgically resected huge retroperitoneal malignant peripheral nerve sheath tumors in 2 patients with sporadic type I neurofibromatosis. One patient survived 10 months and the other survived 3 months after operation. Retroperitoneal malignant peripheral nerve sheath tumor shows a poor prognosis even after surgical resection because of frequent recurrence and the lack of effective adjuvant therapy. Early diagnosis and development of new adjuvant therapy are required to effectively treat this malady.
Cafe-au-Lait Spots
;
Early Diagnosis
;
Humans
;
Neurilemmoma*
;
Neurofibroma
;
Neurofibromatoses*
;
Neurofibromatosis 1
;
Peripheral Nerves
;
Prognosis
;
Recurrence
8.A Clinical Study on Neurofibromatosis Evaluation by Riccardi's Classification.
Myung Ki HYUN ; Doo Chan MOON ; Kyung Sool KWON ; Tae Ahn CHUNG
Korean Journal of Dermatology 1990;28(2):194-201
Clinical study on 62 patients (26 males and 36 females) with neurofibromatosis seen during past ten years at the Department of Dermatology, Pusan National Universitg Hospital, was made the variable clinical manifestations of the disease and Riccardis ciassification were emphasized. The results were as follows . 1) Family history was noted in 32 cases(51.6%) and exhibited autosomal dominant inheritance pattern. 2) Cutaneous neurofibromas were found in 52 cases(83.8%). 3) Cafe-au-lait spots, measuring greater than 1.5cm in its longest diameter, were found in 60 cases(96.8%) and 44 cases(71.0%) had more than 6 in number. 4) Among associated abnormalities were,' mental retardation(20,9%), skeletal abnormalities(11.2%), seizure, severe headache, etc. 5) According to Riccardis classification, 38 cases could be classified as type I, 28 cases(73.7%); type II, 0 case ; type III, 1 case(2.6%); type IV, 3 cases(7, 9%); type V, 1 case(2.6%); type VI, 4 cases(10.5%); type VII, l case(2.6%); and type VIII, 0 case.
Busan
;
Cafe-au-Lait Spots
;
Classification*
;
Dermatology
;
Headache
;
Humans
;
Inheritance Patterns
;
Male
;
Neurofibroma
;
Neurofibromatoses*
;
Seizures
9.A Case of Segmental Neurofibromatosis.
Jin Hyouk CHOI ; Soon Wook KWON ; Moo Kyu SUH ; Ho Chung LEE ; Sung Wook LIM ; Jeong Woo LEE ; Jung Ran KIM
Korean Journal of Dermatology 2003;41(6):820-822
Segmental neurofibromatosis(neurofibromatosis type V) is rare disorder characterized by limitation of cafe-au-lait spots and neurofibroma or only neurofibroma on a given unilateral segment of the body. We report a case of segmental neurofibromatosis that developed in a 58-year-old male. The skin lesion was situated on the right antecubital area and wrist in the distribution of dermatomes C5 and C6. Histopathologic examination showed well-demarcated, non-encapsulated tumor of the dermis was composed of thin wavy collagenous fibers and loosely spaced spindle cells with elongated wavy nuclei. The patient was treated with surgical excision and carbon dioxide laser.
Cafe-au-Lait Spots
;
Collagen
;
Dermis
;
Humans
;
Lasers, Gas
;
Male
;
Middle Aged
;
Neurofibroma
;
Neurofibromatoses*
;
Skin
;
Wrist
10.Two Cases of Plexiform Neurilemmoma.
Sung Eun CHANG ; Yeon Soon LIM ; Jee Ho CHOI ; Kyung Jeh SUNG ; Kee Chan MOON ; Jai Kyoung KOH
Korean Journal of Dermatology 1999;37(4):510-513
Plexiform neurilemmoma is a relatively rare, benign peripheral nerve sheath tumor, whieh usually arises in either the dermis or subcutaneous tissue. These tumors may occur singly or as multiple lesions (plexiform neurilemmomatosis), We report an unusual case of plexiform neurilemmomatosis associated with cafe au lait spots reminiscent of neurofibromatosis clinically and another case of plexiform neurilemmoma on the finger. A Biopsy revealed the characteristic palisaded arrangement of spindle cells within well circumscribed elongated nodules, The skin lesions were completely excised without recurrence thereafter.
Biopsy
;
Cafe-au-Lait Spots
;
Dermis
;
Fingers
;
Neurilemmoma*
;
Neurofibromatoses
;
Peripheral Nerves
;
Recurrence
;
Skin
;
Subcutaneous Tissue