1.Congenital Café-au-Lait Spot and Sequentially Occurred Nevus Spilus.
Annals of Dermatology 2004;16(4):191-193
No abstract available.
Cafe-au-Lait Spots
;
Nevus*
2.Histopathological Observation of Cafe au Lait Spots.
Sung Jun CHOI ; Hee Joon YU ; Sook Ja SOHN
Korean Journal of Dermatology 1986;24(4):506-509
We observed 17 cases of cafe au lait spots histopathplogi ally. Out of 17 cases, 9 cases were neurofibromatosis with neurofibromas, 6 cases were neurofibromatosis without neurofibroma, and 2 cases were normal healthy persons. The results were as follows. l. In all 17 cases, melanin pigment was increased in melanocytes and keratinocytes. 2. Griant pigment granules were identified only in 3 cases of neurofibromatosis with neurofibromas.
Cafe-au-Lait Spots*
;
Humans
;
Keratinocytes
;
Melanins
;
Melanocytes
;
Neurofibroma
;
Neurofibromatoses
3.Isodicentric Chromosome 15 Syndrome in a Korean Patient With Cafe-au-lait Spots.
John Hoon RIM ; Hee Jung CHUNG ; Saeam SHIN ; Seo Jin PARK ; Jong Rak CHOI
Annals of Laboratory Medicine 2015;35(4):474-476
No abstract available.
Cafe-au-Lait Spots*
;
Chromosomes, Human, Pair 15*
;
Humans
4.Treatment of Hyperpigmented Disease with 4-Isopropylcatechol.
Dong Gil BYUN ; Joung Hoe KIM ; Yang Ja PARK ; Soon Bok LEE
Korean Journal of Dermatology 1975;13(1):5-7
Disfiguring hyperpigmentation of the exposed areas may have impartant and lasting effects on the emotional well-being of the patient. And many attempts to treat areas of hyperpigmentation have been earried out, but all of them are not very successful. Recently 4-isopropylcatechol has been known to inhibit melanin pigmentation with a selective action on melanocytes either destroying or inactivating the melanocytes experimentally. There is no report on its clinical trial till now. In this study, 1% 4-isopropylcatechol cream was topieally applied to the hyperpigmented lesions of 29 patieots of melasma, freckle, and cafe-au-lait spot. The bleaching effect on meiasmas was very satisfactory in all patients but coantact dermatltis in 3 patients and reticular hyperpigmentation with areas of depigmented spots in one patient were developed as the side effects of the drug. Freckle and cafe-au-Iait spots were not bleached.
Cafe-au-Lait Spots
;
Humans
;
Hyperpigmentation
;
Melanins
;
Melanocytes
;
Melanosis
;
Pigmentation
5.A Case Congenital Pseudarthrosis of Tibia
Te Hyun YOON ; Young Hwan SHIN ; Ok Suck KIM
The Journal of the Korean Orthopaedic Association 1979;14(4):648-652
Congenital pseudarthrosis of the tibia is a condition most often combined with cafe-au-lait spots and neurofibromatosis. It is notoriously difficult to attain a sound bony union. Compression plating and screw fixation with massive bone graft resulted in successful union in our case.
Cafe-au-Lait Spots
;
Neurofibromatoses
;
Pseudarthrosis
;
Tibia
;
Transplants
6.A Case of Segmental Neurofibromatosis.
Gwang Seong CHOI ; Jeung LEE ; Duck Hwan WON ; Sang Wahn KOO ; Joo Heung LEE ; Young Keun KIM
Annals of Dermatology 1999;11(2):109-111
Segmental neurofibromatosis is a rare disorder characterized by cafe-au-lait spots and neurofibrobmas, or only neurofibroma, limited to one region of the body. Disease-associated systemic involvement is uncommon. Most patients with segmental neurofibromatosis do not have a family history of neurofibromatosis. In Korea, there have been 3 reported cases of segmental neurofibromatosis. None of them had caf6-au-fait spots, systemic involvement, or family history. This report describes a case of segmental neurofibromatosis in a 25-year-old woman who had Becker's nevus-like cafe-au-lait spots and this was linked to the presence of Fanconi's syndrome in a second degree relative of the patient.
Adult
;
Cafe-au-Lait Spots
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Female
;
Humans
;
Korea
;
Neurofibroma
;
Neurofibromatoses*
;
Neurofibromatosis 1
7.A Case of Elephantiasis Neuromatosa.
Sae Hyun PYUN ; Dong Seok KIM ; Sang Won KIM
Korean Journal of Dermatology 1988;26(2):241-246
We report herein a case of elephantiasis neuromatosa seen in neurofibromatosis patient, who was a 33-year-old male and had been diagnosed at the age of 13. Since that time on, small nodule present on the mid-back area led to develop grotesquely large, dark-brown colored, flabby mass with thick verucoid skin change, measuring about 30 * 20cm in size. Histopathologic examination of excised mass demonstrated moderate hyperplasia of epidermis and typical neurofibroma findings with soft tissue and fibrous tissue overgrowth, but no atypical cells. The electron microscopic study showed many perineurial cells surrounded by the continuous bssal lamina of fibroblsst in the dermal lesion and numerous giant pigmented granules in melanocyte and basal keratinocyte in the cafe-au-lait spot.
Adult
;
Cafe-au-Lait Spots
;
Elephantiasis*
;
Epidermis
;
Humans
;
Hyperplasia
;
Keratinocytes
;
Male
;
Melanocytes
;
Neurofibroma
;
Neurofibromatoses
;
Skin
8.A Case of Segmental Neurofibromatosis.
Tae Kyung LEE ; Doo Chan MOON ; Kyung Sool KWON ; Tae Ahn CHUNG
Korean Journal of Dermatology 1987;25(5):696-699
A 61-year-old female had neurofibromas situated on the right side of upper trunk, shoulder and neck in the distribution of dermatomes C3 and C4(right), which developed 3 years ago. There were not cafe-au-lait spots, axillary frecklings, or Lisch nodule (iris pignented hamartoma). Biopsy specimen showed collagenous wavy fibrils among which spindle-shaped and round cells were embedded as seen in the typical neurofibroma. This case was considered to be a segmental form of von Recklinghausen's disease.
Biopsy
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Cafe-au-Lait Spots
;
Collagen
;
Female
;
Humans
;
Middle Aged
;
Neck
;
Neurofibroma
;
Neurofibromatoses*
;
Neurofibromatosis 1
;
Shoulder
9.A Case of Malignant Melanoma in a Patient with Segmental Neurofibromatosis.
Hyo Chan JANG ; Gun PARK ; Joon Soo PARK ; Sung Woo LEE ; Hyun CHUNG ; Sang Won KIM
Korean Journal of Dermatology 2005;43(6):800-803
Neurofibromatosis, like malignant melanoma, is believed to be a disorder of neural crest origin, but a definite association between these two diseases has not been established. We report a patient with malignant melanoma and with segmental neurofibromatosis. The malignant melanoma was not related to neurofibromas. Physical examination revealed no cafe-au-lait spots, axillary freckles, or Lish nodules. His family history was negative for neurofibromatosis or malignant melanoma.
Cafe-au-Lait Spots
;
Humans
;
Melanoma*
;
Melanosis
;
Neural Crest
;
Neurofibroma
;
Neurofibromatoses*
;
Physical Examination
10.A Case of Neurofibromatosis with Giant Pigmentation, Diffuse Neurofibromas and a Pigmented Neurofibroma.
Yun Deok CHOI ; Mi Seon KANG ; Si Hyung CHO ; Sung Wook PARK
Korean Journal of Dermatology 2004;42(11):1517-1520
A 31-year-old man presented with an erythematous tumor within a giant pigmentation on the left arm, which was partially covered with hairs and had a few subcutaneous nodules within it. Also he had a bluish tumor on the left palm, multiple tumors and cafe au lait spots on the upper trunk. Histologic examination from the tumor, pigmentation and subcutaneous nodules on the left arm, and the tumors on the upper trunk and left palm all revealed neurofibromas. Interestingly, the rare types of the neurofibromas, diffuse and pigmented neurofibroma were included in these.
Adult
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Arm
;
Cafe-au-Lait Spots
;
Hair
;
Humans
;
Neurofibroma*
;
Neurofibromatoses*
;
Pigmentation*