The question, “what does life mean?" used to be considered as a paradigm of philosophical investigation. As a researcher, life is meaningless without paradigm and perspective. These are indispensable in peoples' lives as we encounter research in our daily lives. According to James Tartaglia (Veal, 2017), when properly defined, the topic of life's purpose is "the keystone of philosophy," serving to "lock its traditional preoccupations in place" and "allow them to bear weight in an intellectual culture dominated by science." He also contends that we should consider this idea as he rejects the premise of the question and draw the conclusion that "life is meaningless." More precisely, James Tartaglia is one philosopher who is not at all happy about it; in fact, he appears to be absolutely furious about it, as readers who have read this journal's recent symposium on Thaddeus Metz's book Meaning in Life: An Analytic Study would be aware. What enrages Tartaglia the most, it seems, is that the "traditional" topic of life's meaning has been completely disregarded by what he refers to as the "new paradigm" in analytic philosophy, which is purportedly devoted to exploring this question. He further states that the conventional question of life's purpose is not only the only genuine, legitimately philosophical inquiry of life's meaning, but it is also the most important one.
COVID-19

Introduction: Globally, COVID – 19 (SARS COV -2) became an enormous challenge with serious threat to the healthcare workers. This study aimed to provide the psychological coping mechanisms among healthcare workers in tertiary hospital during the COVID-19 pandemic in the locale of Eastern Visayas. Objective: This study was conducted to determine the psychological coping mechanisms among healthcare workers in tertiary hospital during the COVID-19 pandemic. The secondary objectives were to determine the demographic profile of health care workers as to: age, sex, civil status, profession and area of assignment, to identify the issues of concern that contribute to the mental or psychological stress affecting the healthcare workers, to identify the psychological coping mechanisms of healthcare workers to ease their stress and to determine the correlation between issues of concern and coping mechanisms to the demographic profile of the healthcare workers. Methods: Utilized a cross-sectional descriptive study with analytical component. Sample size of 142 was computed using the Epi Info 7 software with confidence interval of 95% and the margin of error of 5%. Descriptive analysis was utilized to identify the socio- demographic profile of HCWs and Pearson r tests in SPSS used in correlation to issues of concern and psychological coping mechanisms. Results: One hundred forty two healthcare workers were included in the study. Of these, almost all respondents belong to aged 20-39 (92.3%). Majority were female and single. As to profession, many were physicians and nurses while as to area of assignments, some in the COVID Ward (24.6%). As to issues of concern, the results showed moderately in physical issues (2.55), mental and emotional issues (2.12). With regards to coping mechanisms, appraisal- focused (adaptive –cognitive) (3.55), emotion- focused (3.50) and problem- focused (adaptive – behavioral) coping mechanisms (3.18) were all very important. The correlational analysis showed that issues of concern and psychological coping mechanisms experienced by HCWs were not significantly related or associated to their demographics profile. Conclusion Based on the findings, the appraisal- focused (adaptive – cognitive), emotion- focused and problem- focused (adaptive – behavioral) coping mechanisms were all very important coping mechanisms among HCWs. Demographic profiles were not significantly associated with issues of concern and psychological coping mechanisms of HCWs in a tertiary hospital during COVID-19 pandemic.
COVID-19

Introduction: The coronavirus pandemic has affected millions worldwide. Better understanding of COVID-19 in pediatric hematology-oncology patients in a resource-limited setting is crucial to improve care as the pandemic ensues. Objectives: This study describes the clinical profile and outcomes of pediatric hematology oncology patients with COVID-19 seen at the Philippine General Hospital (PGH). Methods: A retrospective, descriptive review of pediatric hematology oncology patients with COVID-19 seen between March 2020 to March 2021 in PGH was done. Results: Forty patients were identified. Seventeen percent had non-malignant hematologic conditions, 40% had leukemias, and 42.5% had solid tumors. Fever and cough were the most common manifestations. Seventy-six percent were on treatment, 9% were newly diagnosed, and 7% were in relapse or disease progression. Fifty-five percent had mild COVID-19; 5% and 2.5% had severe and critical COVID-19, respectively. Thirty-seven percent were asymptomatic. Cancer-related therapy was placed on hold for most patients. There were two mortalities, none was due to COVID-19. Conclusion Results suggest that patients with hematologic and oncologic conditions have a mild course, with majority showing recovery from COVID-19. Delays in cancer-related therapy however, may contribute to disease progression and mortality.
COVID-19

Background: The internet contains both accurate and false coronavirus-related information. Is the public equipped with electronic health literacy in navigating online material to make informed health decisions? Objective: This study measured Filipino adults’ perceived level of COVID-19-related eHealth literacy, and how this affects their adherence to preventive practices against COVID-19 infection. Methods: In this analytical cross-sectional study, data were collected from 345 adult respondents who were patients, and their companions, consulting in Healthway Family Clinics in Marikina and Rizal. They answered self-administered electronic questionnaires in English or Filipino. The data collection tool was adapted from the Coronavirus-Related eHealth Literacy Scale (CoV-eHEALS) with permission from the authors. Pearson correlation determined the relationship between mean CoV-eHEALS and mean Protective Behavior Adherence (PBA) score. ANOVA determined the relationship of CoV-eHEALS and PBA with sociodemographic variables. Results: Higher Covid-related eHealth literacy is associated with better adherence to protective behaviors against COVID-19. The overall mean CoV-eHEALS is 23.67 while the overall mean PBA score is 3.81 (r=0.32). Younger age, female sex, and high educational attainment are associated with high CoV-eHEALS. Female sex and high educational attainment are associated with high PBA score Conclusion eHealth literacy is essential for COVID-19 awareness since it influences the public‘s engagement in preventive behavior. Sociodemographic variables should be considered in health education, targeting individuals of younger age, male sex, and lower education. Evaluation of the reliability of online sources Filipinos use to gather health-related information is a possible focus for future research.
COVID-19

The Covid pandemic nearly brought our lives into a different dimension beyond our imagination. Measures to ensure the safety of everyone have never been stricter. The education system had to deal with similar restrictions. Everyone shifted to online virtual classes, which has never been easy to both the teachers and students. Not only are we concerned of our responsibilities as educators but responsive to the needs of students and patients as well during these times of uncertainties. This article briefly describes my personal insight on teaching medicine and how patients continue to take part in the learning process of students despite restrictions.

Introduction: Cancer patients are more susceptible to coronavirus disease-19 (COVID-19) infection because they are immunosuppressed by their disease or therapy, most of them have coexisting medical conditions, and they frequently visit hospitals for treatment and surveillance. Objective: The objective of this study was to determine the prevalence of COVID-19 infection among gynecologic oncology patients receiving treatment in a COVID-19 referral hospital. Materials and Methods: A descriptive, cross-sectional study involving 47 gynecologic cancer patients receiving treatment from June 2020 to December 2020 was performed. All patients underwent SARS-CoV-2 reverse transcription-polymerase chain reaction (RT-PCR) swab test and symptom and exposure assessment before the start of cancer treatment. Patients with negative SARS-CoV-2 RT-PCR swab test results received their planned treatment, and a repeat swab test and triage assessment were done midtreatment and after treatment. Results: Five (10.6%) patients had positive baseline SARS-CoV-2 RT-PCR swab results, but all proceeded with treatment after negative results were obtained. Only 1 (2.13%) patient had a positive SARS-CoV-2 RT-PCR swab test result at midtreatment. All patients had no COVID-19-associated symptoms and none of them tested positive for COVID-19 infection posttreatment. Conclusion The prevalence of COVID-19 infection among gynecologic cancer patients receiving cancer treatment is 2.13%. All patients who had positive SARS-CoV-2 RT-PCR swab test results at baseline or midtreatment were able to continue and complete treatment. There were no severe clinical events or mortalities among those affected with COVID-19 infection.
COVID-19

This case illustrates the myriad neuropsychiatric symptoms associated with the direct and indirect exposure to COVID-19 infection. The disruption in our daily routines, the uncertainty brought on by the then novel and unknown condition, the specter of death and the “horror” stories that spread through the grapevine during the lockdown shook the foundations of our existence. To make matters even worse, the government protocols required those infected to move away from the comfort of the familiar and the emotional support of family and friends.
COVID-19

This document offers guidance to help the ophthalmologist plan for the safe resumption of elective surgical care. There are 4 sections: (I) COVID-19 Awareness, (II) Preparedness, (III) Patient Issues, and (IV) Delivery of Safe and High-Quality Care. Each section contains key issues to be addressed before elective surgery may be safely reinstituted. Understanding the capabilities of health facilities (e.g., testing, operating rooms) as well as the potential limitations in manpower and supplies will remain important, while keeping an eye out on subsequent waves of COVID-19.
COVID-19

With the resumption of elective surgeries during this COVID-19 pandemic, surgeons and facilities should implement infection prevention and control measures to ensure the safety of patients and health care workers. This advisory highlights the key principles, risk stratification considerations, and recommended approach regarding Covid-19 testing prior to elective ophthalmic surgeries.
COVID-19

Key Findings There is some short-term benefit from the use of mesenchymal stem cell therapy for severe COVID-19 in a lowquality, small randomized controlled trial (RCT). Further studies, ideally with good quality RCTs, are needed to confirm benefit and safety. • Mesenchymal stem cells (MSCs) are non-hematopoietic adult stem cells that are able to self-renew and differentiate into various cells of any cell lineage. MSCs have the ability to migrate (homing) to damaged tissue for repair and regeneration, as well as signal other cells to help in tissue repair. It can effect cellular differentiation, consequently shifting the immune system from Th1 to Th2 responses.1,2 • A recent review showed improved disease-associated parameters in experimental acute respiratory distress syndrome (ARDS).3 • We found three studies (one case report, one prospective cohort, and one small randomized controlled trial) reporting the effects of MSC on COVID-19. Based on low-quality evidence, it appeared that human umbilical cord blood-derived MSC, given after failure to improve with standard treatment, had beneficial effects in terms of earlier onset of clinical improvement among individuals with severe or critical COVID-19. However, 28-day clinical improvement and mortality were not significantly different compared to standard treatment. There was no reported adverse reaction. • There are 52 registered and ongoing clinical trials to investigate the efficacy and safety of mesenchymal stem cells as treatment for COVID-19. • Mesenchymal stem cell therapy is not included in any of the existing guidelines for the treatment of COVID-19.
Covid-19